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Items: 1 to 20 of 54

1.
Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
Marina Guillén-Yunta, Víctor Valcárcel-Hernández, Ángel García-Aldea, Guadalupe Soria, José Manuel García-Verdugo, Ana Montero-Pedrazuela, Ana Guadaño-Ferraz
Fluids Barriers CNS. 2023; 20: 79. Published online 2023 Nov 3. doi: 10.1186/s12987-023-00481-w
PMCID:
PMC10623792
ArticlePDF–12M
2.
Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice
Kenji Ohba, Melvin Khee-Shing Leow, Brijesh Kumar Singh, Rohit Anthony Sinha, Ronny Lesmana, Xiao-Hui Liao, Sujoy Ghosh, Samuel Refetoff, Judy Chia Ghee Sng, Paul Michael Yen
Endocrinology. 2016 Apr; 157(4): 1660–1672. Published online 2016 Feb 11. doi: 10.1210/en.2015-1848
PMCID:
PMC4816733
Article
3.
The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency
Alfonso Massimiliano Ferrara, Xiao-Hui Liao, Honggang Ye, Roy E. Weiss, Alexandra M. Dumitrescu, Samuel Refetoff
Endocrinology. 2015 Nov; 156(11): 3889–3894. Published online 2015 Aug 31. doi: 10.1210/en.2015-1234
PMCID:
PMC4606752
Article
4.
Placenta Passage of the Thyroid Hormone Analog DITPA to Male Wild-Type and Mct8-Deficient Mice
Alfonso Massimiliano Ferrara, Xiao-Hui Liao, Pilar Gil-Ibáñez, Juan Bernal, Roy E. Weiss, Alexandra M. Dumitrescu, Samuel Refetoff
Endocrinology. 2014 Oct; 155(10): 4088–4093. Published online 2014 Jul 22. doi: 10.1210/en.2014-1085
PMCID:
PMC4164925
Article
5.
Retinoic Acid Induces Expression of the Thyroid Hormone Transporter, Monocarboxylate Transporter 8 (Mct8)
Takahiko Kogai, Yan-Yun Liu, Laura L. Richter, Kaizeen Mody, Hiroyuki Kagechika, Gregory A. Brent
J Biol Chem. 2010 Aug 27; 285(35): 27279–27288. Published online 2010 Jun 23. doi: 10.1074/jbc.M110.123158
PMCID:
PMC2930727
ArticlePDF–3.4M
6.
A Thyroid Hormone Analog with Reduced Dependence on the Monocarboxylate Transporter 8 for Tissue Transport
Caterina Di Cosmo, Xiao-Hui Liao, Alexandra M. Dumitrescu, Roy E. Weiss, Samuel Refetoff
Endocrinology. 2009 Sep; 150(9): 4450–4458. Published online 2009 Jun 4. doi: 10.1210/en.2009-0209
PMCID:
PMC2736078
Article
7.
Importance of Monocarboxylate Transporter 8 for the Blood-Brain Barrier-Dependent Availability of 3,5,3′-Triiodo-l-Thyronine
Ainhoa Ceballos, Monica M. Belinchon, Eduardo Sanchez-Mendoza, Carmen Grijota-Martinez, Alexandra M. Dumitrescu, Samuel Refetoff, Beatriz Morte, Juan Bernal
Endocrinology. 2009 May; 150(5): 2491–2496. Published online 2009 Jan 15. doi: 10.1210/en.2008-1616
PMCID:
PMC2671898
Article
8.
The Differential Effect of a Shortage of Thyroid Hormone Compared with Knockout of Thyroid Hormone Transporters Mct8 and Mct10 on Murine Macrophage Polarization
Esmée Hoen, Franka M. Goossens, Kim Falize, Steffen Mayerl, Anne H. van der Spek, Anita Boelen
Int J Mol Sci. 2024 Feb; 25(4): 2111. Published online 2024 Feb 9. doi: 10.3390/ijms25042111
PMCID:
PMC10889717
ArticlePDF–3.5M
9.
Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function
Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Bente Siebels, Hartmut Schlüter, Steffen Mayerl, Heike Heuer, Daniel Robert Engel
Cells. 2023 Oct; 12(20): 2487. Published online 2023 Oct 19. doi: 10.3390/cells12202487
PMCID:
PMC10605308
ArticlePDF–3.5M
10.
Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice
Jiesi Chen, Eva Salveridou, Lutz Liebmann, Sivaraj M. Sundaram, Denica Doycheva, Boyka Markova, Christian A. Hübner, Anita Boelen, W. Edward Visser, Heike Heuer, Steffen Mayerl
Int J Mol Sci. 2023 Feb; 24(4): 3452. Published online 2023 Feb 9. doi: 10.3390/ijms24043452
PMCID:
PMC9966820
ArticlePDF–2.7M
11.
TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice
Jonathan Rochus Reinwald, Wolfgang Weber-Fahr, Alejandro Cosa-Linan, Robert Becker, Markus Sack, Claudia Falfan-Melgoza, Natalia Gass, Urs Braun, Christian Clemm von Hohenberg, Jiesi Chen, Steffen Mayerl, Thomas F. Muente, Heike Heuer, Alexander Sartorius
Int J Mol Sci. 2022 Dec; 23(24): 15547. Published online 2022 Dec 8. doi: 10.3390/ijms232415547
PMCID:
PMC9779161
ArticlePDF–6.0M
12.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome
Gandhari Maity-Kumar, Lisa Ständer, Meri DeAngelis, Sooyeon Lee, Anna Molenaar, Lore Becker, Lillian Garrett, Oana V. Amerie, Sabine M. Hoelter, Wolfgang Wurst, Helmut Fuchs, Annette Feuchtinger, Valerie Gailus-Durner, Cristina Garcia-Caceres, Ahmed E. Othman, Caroline Brockmann, Vanessa I. Schöffling, Katja Beiser, Heiko Krude, Piotr A. Mroz, Susanna Hofmann, Jan Tuckermann, Richard D. DiMarchi, Martin Hrabe de Angelis, Matthias H. Tschöp, Paul T. Pfluger, Timo D. Müller
Mol Metab. 2022 Dec; 66: 101616. Published online 2022 Oct 18. doi: 10.1016/j.molmet.2022.101616
PMCID:
PMC9626936
ArticlePDF–2.8M
13.
IGSF1 Deficiency Leads to Reduced TSH Production Independent of Alterations in Thyroid Hormone Action in Male Mice
Emilie Brûlé, Tanya L Silander, Ying Wang, Xiang Zhou, Beata Bak, Stefan Groeneweg, Daniel J Bernard
Endocrinology. 2022 Aug; 163(8): bqac092. Published online 2022 Jun 16. doi: 10.1210/endocr/bqac092
PMCID:
PMC9258739
Article
14.
Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone
Cristina Luongo, Lucile Butruille, Anthony Sébillot, Karine Le Blay, Markus Schwaninger, Heike Heuer, Barbara A. Demeneix, Sylvie Remaud
Stem Cell Reports. 2021 Feb 9; 16(2): 337–353. Published online 2021 Jan 14. doi: 10.1016/j.stemcr.2020.12.009
PMCID:
PMC7878696
ArticlePDF–2.5M
15.
Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling
Steffen Mayerl, Heike Heuer, Charles ffrench-Constant
Stem Cell Reports. 2020 May 12; 14(5): 845–860. Published online 2020 Apr 16. doi: 10.1016/j.stemcr.2020.03.014
PMCID:
PMC7220957
ArticlePDF–9.1M
16.
Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10)
David S. Sharlin, Lily Ng, François Verrey, Theo J. Visser, Ye Liu, Rafal T. Olszewski, Michael Hoa, Heike Heuer, Douglas Forrest
Sci Rep. 2018; 8: 4403. Published online 2018 Mar 13. doi: 10.1038/s41598-018-22553-w
PMCID:
PMC5849681
ArticlePDF–2.6M
17.
MCT8 Deficiency in Male Mice Mitigates the Phenotypic Abnormalities Associated With the Absence of a Functional Type 3 Deiodinase
J. Patrizia Stohn, M. Elena Martinez, Kassey Matoin, Beatriz Morte, Juan Bernal, Valerie Anne Galton, Donald St Germain, Arturo Hernandez
Endocrinology. 2016 Aug; 157(8): 3266–3277. Published online 2016 Jun 1. doi: 10.1210/en.2016-1162
PMCID:
PMC4967121
Article
18.
Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis
Steffen Mayerl, Julia Müller, Reinhard Bauer, Sarah Richert, Celia M. Kassmann, Veerle M. Darras, Katrin Buder, Anita Boelen, Theo J. Visser, Heike Heuer
J Clin Invest. 2014 May 1; 124(5): 1987–1999. Published online 2014 Apr 1. doi: 10.1172/JCI70324
PMCID:
PMC4001533
ArticlePDF–5.6M
19.
Mct8-Deficient Mice Have Increased Energy Expenditure and Reduced Fat Mass That Is Abrogated by Normalization of Serum T3 Levels
Caterina Di Cosmo, Xiao-Hui Liao, Honggang Ye, Alfonso Massimiliano Ferrara, Roy E. Weiss, Samuel Refetoff, Alexandra M. Dumitrescu
Endocrinology. 2013 Dec; 154(12): 4885–4895. Published online 2013 Sep 12. doi: 10.1210/en.2013-1150
PMCID:
PMC3836073
Article
20.
Increased Oxidative Metabolism and Neurotransmitter Cycling in the Brain of Mice Lacking the Thyroid Hormone Transporter Slc16a2 (Mct8)
Tiago B. Rodrigues, Ainhoa Ceballos, Carmen Grijota-Martínez, Barbara Nuñez, Samuel Refetoff, Sebastian Cerdán, Beatriz Morte, Juan Bernal
PLoS One. 2013; 8(10): e74621. Published online 2013 Oct 1. doi: 10.1371/journal.pone.0074621
PMCID:
PMC3788064
ArticlePDF–376K

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