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Select item 97404211.

Immunogenic Death of Hepatocellular Carcinoma Cells in Mice Expressing Caspase-Resistant ROCK1 Is Not Replicated by ROCK Inhibitors

Gregory Naylor, Linda Julian, Steven Watson-Bryce, Margaret Mullin, Robert J. Nibbs, Michael F. Olson

Cancers (Basel) 2022 Dec; 14(23): 5943. Published online 2022 Nov 30. doi: 10.3390/cancers14235943

PMCID:: PMC9740421

Article PDF–5.4M

Select item 96493782.

ROCK1 regulates insulin secretion from β-cells

Byung-Jun Sung, Sung-Bin Lim, Won-Mo Yang, Jae Hyeon Kim, Rohit N. Kulkarni, Young-Bum Kim, Moon-Kyu Lee

Mol Metab. 2022 Dec; 66: 101625. Published online 2022 Oct 29. doi: 10.1016/j.molmet.2022.101625

PMCID:: PMC9649378

Article PDF–2.1M

Select item 90471123.

Vascular Smooth Muscle ROCK1 Contributes to Hypoxia-Induced Pulmonary Hypertension Development in Mice

Krishna C. Penumatsa, Adit A. Singhal, Rod R. Warburton, Michael D. Bear, Chinmayee D. Bhedi, Sabina Nasirova, Jamie L. Wilson, Guanming Qi, Ioana R. Preston, Nicholas S. Hill, Barry L. Fanburg, Young-Bum Kim, Deniz Toksoz

Biochem Biophys Res Commun. Author manuscript; available in PMC 2023 May 14.

Published in final edited form as: Biochem Biophys Res Commun. 2022 May 14; 604: 137–143. Published online 2022 Mar 9. doi: 10.1016/j.bbrc.2022.02.064

PMCID:: PMC9047112

Article PDF–1.0M

Select item 88995664.

Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation

Minghui Li, Xing Lyu, James Liao, Victoria P. Werth, Ming-Lin Liu

Theranostics. 2022; 12(5): 2133–2149. Published online 2022 Feb 7. doi: 10.7150/thno.66457

PMCID:: PMC8899566

Article PDF–3.2M

Select item 80874485.

Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression

Linda Julian, Gregory Naylor, Grant R Wickman, Nicola Rath, Giovanni Castino, David Stevenson, Sheila Bryson, June Munro, Lynn McGarry, Margaret Mullin, Alistair Rice, Armandodel Del Río Hernández, Michael F Olson

eLife. 2021; 10: e61983. Published online 2021 Apr 19. doi: 10.7554/eLife.61983

PMCID:: PMC8087448

Article PDF–11M

Select item 67415686.

Streptococcal M1 Protein-Provoked CXC Chemokine Formation, Neutrophil Recruitment and Lung Damage Are Regulated by Rho-Kinase Signaling

Songen Zhang, Milladur Rahman, Su Zhang, Heiko Herwald, Zhongquan Qi, Bengt Jeppsson, Henrik Thorlacius

J Innate Immun. 2012 Jun; 4(4): 399–408. Published online 2012 Mar 16. doi: 10.1159/000336182

PMCID:: PMC6741568

Article PDF–1.1M

Select item 66333957.

Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure

Max B. Butler, Nina E. Short, Eirini Maniou, Paula Alexandre, Nicholas D. E. Greene, Andrew J. Copp, Gabriel L. Galea

J Cell Sci. 2019 Jul 1; 132(13): jcs230300. Published online 2019 Jul 1. doi: 10.1242/jcs.230300

PMCID:: PMC6633395

Article

Select item 58425038.

Chondroitin Sulfate Impairs Neural Stem Cell Migration Through ROCK Activation

Layla T. Galindo, Mayara T. V. V. Mundim, Agnes S. Pinto, Gabrielly M. D. Chiarantin, Maíra E. S. Almeida, Marcelo L. Lamers, Alan R. Horwitz, Marinilce F. Santos, Marimelia Porcionatto

Mol Neurobiol. 2018; 55(4): 3185–3195. Published online 2017 May 5. doi: 10.1007/s12035-017-0565-8

PMCID:: PMC5842503

Article PDF–1.6M

Select item 47408449.

ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

Hui Peng, Yuanqing Li, Cheng Wang, Jun Zhang, Yanru Chen, Wenfang Chen, Jin Cao, Yanlin Wang, Zhaoyong Hu, Tanqi Lou

Sci Rep. 2016; 6: 20304. Published online 2016 Feb 4. doi: 10.1038/srep20304

PMCID:: PMC4740844

Article PDF–1.6M

Select item 472087510.

Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway

H-G Moon, Y Cao, J Yang, J H Lee, H S Choi, Y Jin

Cell Death Dis. 2015 Dec; 6(12): e2016. Published online 2015 Dec 10. doi: 10.1038/cddis.2015.282

Correction in:: Cell Death Dis. 2020 Feb; 11(2): 116.

PMCID:: PMC4720875

Article PDF–2.7M

Select item 448991211.

Dissecting the Mechanisms of Doxorubicin and Oxidative Stress-Induced Cytotoxicity: The Involvement of Actin Cytoskeleton and ROCK1

Lei Wei, Michelle Surma, Gina Gough, Stephanie Shi, Nathan Lambert-Cheatham, Jiang Chang, Jianjian Shi

PLoS One. 2015; 10(7): e0131763. Published online 2015 Jul 2. doi: 10.1371/journal.pone.0131763

PMCID:: PMC4489912

Article PDF–9.7M

Select item 395692512.

Rho-Kinase Activation in Leukocytes Plays a Pivotal Role in Myocardial Ischemia/Reperfusion Injury

Katsunori Kitano, Soichiro Usui, Hiroshi Ootsuji, Shin-ichiro Takashima, Daisuke Kobayashi, Hisayoshi Murai, Hiroshi Furusho, Ayano Nomura, Shuichi Kaneko, Masayuki Takamura

PLoS One. 2014; 9(3): e92242. Published online 2014 Mar 17. doi: 10.1371/journal.pone.0092242

PMCID:: PMC3956925

Article PDF–3.6M

Select item 394248013.

ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment

Michelle Surma, Caitlin Handy, Jiang Chang, Reuben Kapur, Lei Wei, Jianjian Shi

PLoS One. 2014; 9(3): e90758. Published online 2014 Mar 4. doi: 10.1371/journal.pone.0090758

PMCID:: PMC3942480

Article PDF–1.5M

Select item 386530114.

Rho Associated Coiled-Coil Kinase-1 Regulates Collagen-Induced Phosphatidylserine Exposure in Platelets

Swapan K. Dasgupta, Anhquyen Le, Sandra B. Haudek, Mark L. Entman, Rolando E. Rumbaut, Perumal Thiagarajan

PLoS One. 2013; 8(12): e84649. Published online 2013 Dec 16. doi: 10.1371/journal.pone.0084649

PMCID:: PMC3865301

Article PDF–707K

Select item 367477315.

A Co-Receptor Independent Transgenic Human TCR Mediates Anti-Tumor and Anti-Self Immunity in Mice

Shikhar Mehrotra, Amir A. Al-Khami, Jared Klarquist, Shahid Husain, Osama Naga, Jonathan M. Eby, Anuradha K. Murali, Gretchen E. Lyons, Mingli Li, Natali D. Spivey, Håkan Norell, Telma Martins da Palma, Georgiana Onicescu, C. Marcela Diaz-Montero, Elizabeth Garrett-Mayer, David J. Cole, I. Caroline Le Poole, Michael I. Nishimura

J Immunol. Author manuscript; available in PMC 2013 Aug 15.

Published in final edited form as: J Immunol. 2012 Aug 15; 189(4): 1627–1638. Published online 2012 Jul 13. doi: 10.4049/jimmunol.1103271

PMCID:: PMC3674773

Article PDF–2.3M

Select item 352386516.

Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells

Frank A. Suprynowicz, Geeta Upadhyay, Ewa Krawczyk, Sarah C. Kramer, Jess D. Hebert, Xuefeng Liu, Hang Yuan, Chaitra Cheluvaraju, Phillip W. Clapp, Richard C. Boucher, Jr., Christopher M. Kamonjoh, Scott H. Randell, Richard Schlegel

Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49): 20035–20040. Published online 2012 Nov 19. doi: 10.1073/pnas.1213241109