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Select item 86207961.

RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease

Sanjay Awasthi, Ashly Hindle, Neha A. Sawant, Mathew George, Murali Vijayan, Sudhir Kshirsagar, Hallie Morton, Lloyd E. Bunquin, Philip T. Palade, J. Josh Lawrence, Hafiz Khan, Chhanda Bose, P. Hemachandra Reddy, Sharda P. Singh

Cells. 2021 Nov; 10(11): 3113. Published online 2021 Nov 10. doi: 10.3390/cells10113113

PMCID:: PMC8620796

Article PDF–6.1M

Select item 37435082.

RLIP76 Protein Knockdown Attenuates Obesity Due to a High-fat Diet

Sharad S. Singhal, James Figarola, Jyotsana Singhal, Marpadga A. Reddy, Xueli Liu, David Berz, Rama Natarajan, Sanjay Awasthi

J Biol Chem. 2013 Aug 9; 288(32): 23394–23406. Published online 2013 Jul 2. doi: 10.1074/jbc.M113.480194

PMCID:: PMC3743508

Article PDF–5.6M

Select item 34730903.

RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization

Seunghyung Lee, Jeremy G.T. Wurtzel, Sharad S. Singhal, Sanjay Awasthi, Lawrence E. Goldfinger

Cancer Res. Author manuscript; available in PMC 2013 Oct 15.

Published in final edited form as: Cancer Res. 2012 Oct 15; 72(20): 5165–5173. Published online 2012 Aug 17. doi: 10.1158/0008-5472.CAN-12-0468

PMCID:: PMC3473090

Article PDF–927K

Select item 31722884.

RLIP76, a Glutathione-Conjugate Transporter, Plays a Major Role in the Pathogenesis of Metabolic Syndrome

Jyotsana Singhal, Lokesh Nagaprashantha, Rit Vatsyayan, Sanjay Awasthi, Sharad S. Singhal

PLoS One. 2011; 6(9): e24688. Published online 2011 Sep 13. doi: 10.1371/journal.pone.0024688

PMCID:: PMC3172288

Article PDF–819K

Select item 30657785.

Glutathione-Conjugate Transport by RLIP76 is required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Sharad S. Singhal, Dilki Wickramarachchi, Sushma Yadav, Jyotsana Singhal, Kathryn Leake, Rit Vatsyayan, Pankaj Chaudhary, Poorna Lelsani, Sumihiro Suzuki, Shaohua Yang, Yogesh C. Awasthi, Sanjay Awasthi

Mol Cancer Ther. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Mol Cancer Ther. 2011 Jan; 10(1): 16–28. doi: 10.1158/1535-7163.MCT-10-0699

PMCID:: PMC3065778

Article PDF–2.5M

Select item 28286456.

A Central Role of RLIP76 in Regulation of Glycemic Control

Sanjay Awasthi, Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Rit Vatsyayan, Ewa Zajac, Rafal Luchowski, Jozef Borvak, Karol Gryczynski, Yogesh C. Awasthi

Diabetes. 2010 Mar; 59(3): 714–725. Published online 2009 Dec 10. doi: 10.2337/db09-0911

PMCID:: PMC2828645

Article PDF–1.2M

Select item 25869427.

Diminished Drug Transport and Augmented Radiation Sensitivity Caused by Loss of RLIP76

Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Mukesh Sahu, Archana Sehrawat, Sanjay Awasthi

FEBS Lett. Author manuscript; available in PMC 2009 Oct 15.

Published in final edited form as: FEBS Lett. 2008 Oct 15; 582(23-24): 3408–3414. Published online 2008 Sep 18. doi: 10.1016/j.febslet.2008.09.001

PMCID:: PMC2586942

Article PDF–681K

Select item 22685908.

Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein

Claudia Mack, Albert Sickmann, David Lembo, Wolfram Brune

Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8): 3094–3099. Published online 2008 Feb 19. doi: 10.1073/pnas.0800168105

PMCID:: PMC2268590

Article PDF–517K

Select item 20643419.

RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration

Lawrence E. Goldfinger, Celeste Ptak, Erin D. Jeffery, Jeffrey Shabanowitz, Donald F. Hunt, Mark H. Ginsberg

J Cell Biol. 2006 Sep 11; 174(6): 877–888. doi: 10.1083/jcb.200603111

PMCID:: PMC2064341

Article PDF–2.7M

Select item 793768710.

Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS

Sara Dominguez, Eugene Varfolomeev, Robert Brendza, Kim Stark, Joy Tea, Jose Imperio, Hai Ngu, Timothy Earr, Oded Foreman, Joshua D. Webster, Amy Easton, Domagoj Vucic, Baris Bingol

Cell Death Differ. 2021 Mar; 28(3): 915–931. Published online 2020 Sep 29. doi: 10.1038/s41418-020-00625-7

PMCID:: PMC7937687

Article PDF–4.3M

Select item 589945511.

Rlip depletion prevents spontaneous neoplasia in TP53 null mice

Sanjay Awasthi, Joshua Tompkins, Jyotsana Singhal, Arthur D. Riggs, Sushma Yadav, Xiwei Wu, Sharda Singh, Charles Warden, Zheng Liu, Jinhui Wang, Thomas P. Slavin, Jeffrey N. Weitzel, Yate-Ching Yuan, Meenakshi Awasthi, Satish K. Srivastava, Yogesh C. Awasthi, Sharad S. Singhal

Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15): 3918–3923. Published online 2018 Mar 23. doi: 10.1073/pnas.1719586115

PMCID:: PMC5899455

Article PDF–883K

Select item 306577712.

RLIP76 Transports Sunitinib and Sorafenib and Mediates Drug Resistance in Kidney Cancer

Sharad S. Singhal, Archana Sehrawat, Mukesh Sahu, Preeti Singhal, Rit Vatsyayan, Poorna Chandra Rao Lelsani, Sushma Yadav, Sanjay Awasthi

Int J Cancer. Author manuscript; available in PMC 2011 Mar 29.

Published in final edited form as: Int J Cancer. 2010 Mar 15; 126(6): 1327–1338. doi: 10.1002/ijc.24767

PMCID:: PMC3065777

Article PDF–582K

Select item 425461813.

The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration

Seunghyung Lee, Jeremy G.T. Wurtzel, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Oct 30; 454(4): 560–565. Published online 2014 Oct 30. doi: 10.1016/j.bbrc.2014.10.114

PMCID:: PMC4254618

Article PDF–769K

Select item 291668214.

Mitogenic and drug-resistance mediating effects of PKCα require RLIP76

Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Yogesh C. Awasthi, Sanjay Awasthi

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Aug 5.

Published in final edited form as: Biochem Biophys Res Commun. 2006 Sep 22; 348(2): 722–727. Published online 2006 Jul 28. doi: 10.1016/j.bbrc.2006.07.118

PMCID:: PMC2916682

Article PDF–1.1M

Select item 273053015.

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD

Kihoon Han, Myoung-Hwan Kim, Daniel Seeburg, Jinsoo Seo, Chiara Verpelli, Seungnam Han, Hye Sun Chung, Jaewon Ko, Hyun Woo Lee, Karam Kim, Won Do Heo, Tobias Meyer, Hyun Kim, Carlo Sala, Se-Young Choi, Morgan Sheng, Eunjoon Kim

PLoS Biol. 2009 Sep; 7(9): e1000187. Published online 2009 Sep 8. doi: 10.1371/journal.pbio.1000187

PMCID:: PMC2730530

Article PDF–1.6M

Select item 26242616.

The Death Domain Kinase RIP1 Is Essential for Tumor Necrosis Factor Alpha Signaling to p38 Mitogen-Activated Protein Kinase

Thomas H. Lee, Qiaojia Huang, Sarah Oikemus, Jennifer Shank, Juan-Jose Ventura, Nicole Cusson, Richard R. Vaillancourt, Bing Su, Roger J. Davis, Michelle A. Kelliher

Mol Cell Biol. 2003 Nov; 23(22): 8377–8385. doi: 10.1128/MCB.23.22.8377-8385.2003

PMCID:: PMC262426

Article PDF–324K

Select item 464443817.

RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes

Jeremy G.T. Wurtzel, Seunghyung Lee, Sharad S. Singhal, Sanjay Awasthi, Mark H. Ginsberg, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Nov 27.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Nov 27; 467(4): 785–791. Published online 2015 Oct 20. doi: 10.1016/j.bbrc.2015.10.064

PMCID:: PMC4644438

Article PDF–994K

Select item 331799118.

RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer

Kathryn Leake, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi, Sharad S. Singhal

PLoS One. 2012; 7(4): e34582. Published online 2012 Apr 3. doi: 10.1371/journal.pone.0034582

PMCID:: PMC3317991

Article PDF–2.6M

Select item 316571619.

Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis

Krishna M. Irrinki, Karthik Mallilankaraman, Roshan J. Thapa, Harish C. Chandramoorthy, Frank J. Smith, Neelakshi R. Jog, Rajesh Kumar Gandhirajan, Steven G. Kelsen, Steven R. Houser, Michael J. May, Siddharth Balachandran, Muniswamy Madesh

Mol Cell Biol. 2011 Sep; 31(18): 3745–3758. doi: 10.1128/MCB.05303-11

PMCID:: PMC3165716

Article PDF–4.5M

Select item 452141320.

Caspase-8 and c-FLIP_L Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation

Ravi S. Misra, Jennifer Q. Russell, Andreas Koenig, Jennifer A. Hinshaw-Makepeace, Renren Wen, Demin Wang, Hairong Huo, Dan R. Littman, Uta Ferch, Jurgen Ruland, Margot Thome, Ralph C. Budd

J Biol Chem. Author manuscript; available in PMC 2015 Jul 31.

Published in final edited form as: J Biol Chem. 2007 Jul 6; 282(27): 19365–19374. Published online 2007 Apr 26. doi: 10.1074/jbc.M610610200