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Select item 37872611.

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

Jessica A. Hurt, Alex D. Robertson, Christopher B. Burge

Genome Res. 2013 Oct; 23(10): 1636–1650. doi: 10.1101/gr.157354.113

PMCID:: PMC3787261

Article PDF–1.5M

Select item 71456022.

Translation-dependent unwinding of stem–loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs

Takashi Mino, Noriki Iwai, Masayuki Endo, Kentaro Inoue, Kotaro Akaki, Fabian Hia, Takuya Uehata, Tomoko Emura, Kumi Hidaka, Yutaka Suzuki, Daron M Standley, Mariko Okada-Hatakeyama, Shigeo Ohno, Hiroshi Sugiyama, Akio Yamashita, Osamu Takeuchi

Nucleic Acids Res. 2019 Sep 19; 47(16): 8838–8859. Published online 2019 Jul 22. doi: 10.1093/nar/gkz628

PMCID:: PMC7145602

Article PDF–6.1M

Select item 52697423.

RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis

Claire M. Mooney, Eva M. Jimenez-Mateos, Tobias Engel, Catherine Mooney, Mairead Diviney, Morten T. Venø, Jørgen Kjems, Michael A. Farrell, Donncha F. O’Brien, Norman Delanty, David C. Henshall

Sci Rep. 2017; 7: 41517. Published online 2017 Jan 27. doi: 10.1038/srep41517

PMCID:: PMC5269742

Article PDF–2.4M

Select item 31279294.

Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice

Pamela A. Frischmeyer-Guerrerio, Robert A. Montgomery, Daniel S. Warren, Sara K. Cooke, Johannes Lutz, Christopher J. Sonnenday, Anthony L. Guerrerio, Harry C. Dietz

Proc Natl Acad Sci U S A. 2011 Jun 28; 108(26): 10638–10643. Published online 2011 Jun 13. doi: 10.1073/pnas.1019352108

PMCID:: PMC3127929

Article PDF–1.1M

Select item 16368035.

Upf1/Upf2 Regulation of 3′ Untranslated Region Splice Variants of AUF1 Links Nonsense-Mediated and A+U-Rich Element-Mediated mRNA Decay

Lili Banihashemi, Gerald M. Wilson, Neha Das, Gary Brewer

Mol Cell Biol. 2006 Dec; 26(23): 8743–8754. Published online 2006 Sep 25. doi: 10.1128/MCB.02251-05

PMCID:: PMC1636803

Article PDF–545K

Select item 73351716.

C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression

Yu Sun, Aziz Eshov, Jeffrey Zhou, Atagun U. Isiktas, Junjie U. Guo

Nat Commun. 2020; 11: 3354. Published online 2020 Jul 3. doi: 10.1038/s41467-020-17129-0

Correction in:: Nat Commun. 2022; 13: 279.

PMCID:: PMC7335171

Article PDF–2.6M

Select item 70538627.

Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG

Yaojia Cheng, Qiuping Lu, Nannan Shi, Qiongyan Zhou, Jingjing Rong, Liyun Li, Li Wang, Chen Liu

Int J Mol Med. 2020 Apr; 45(4): 1163–1175. Published online 2020 Feb 5. doi: 10.3892/ijmm.2020.4487

PMCID:: PMC7053862

Article PDF–1.2M

Select item 48581588.

Chromatoid Body Protein TDRD6 Supports Long 3’ UTR Triggered Nonsense Mediated mRNA Decay

Grigorios Fanourgakis, Mathias Lesche, Müge Akpinar, Andreas Dahl, Rolf Jessberger

PLoS Genet. 2016 May; 12(5): e1005857. Published online 2016 May 5. doi: 10.1371/journal.pgen.1005857

PMCID:: PMC4858158

Article PDF–8.8M

Select item 66116009.

Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse

Marie-Claude Beauchamp, Anissa Djedid, Kevin Daupin, Kayla Clokie, Shruti Kumar, Jacek Majewski, Loydie Anne Jerome-Majewska

PLoS One. 2019; 14(7): e0219280. Published online 2019 Jul 5. doi: 10.1371/journal.pone.0219280

PMCID:: PMC6611600

Article PDF–1.5M

Select item 447539810.

Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay

Tangliang Li, Yue Shi, Pei Wang, Luis Miguel Guachalla, Baofa Sun, Tjard Joerss, Yu-Sheng Chen, Marco Groth, Anja Krueger, Matthias Platzer, Yun-Gui Yang, Karl Lenhard Rudolph, Zhao-Qi Wang

EMBO J. 2015 Jun 12; 34(12): 1630–1647. Published online 2015 Mar 14. doi: 10.15252/embj.201489947

PMCID:: PMC4475398

Article PDF–4.1M

Select item 859709111.

NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome

Tatsuaki Kurosaki, Hitomi Sakano, Christoph Pröschel, Jason Wheeler, Alexander Hewko, Lynne E. Maquat

Genome Biol. 2021; 22: 317. Published online 2021 Nov 16. doi: 10.1186/s13059-021-02530-9

PMCID:: PMC8597091

Article PDF–1.5M

Select item 3826012.

Mammalian orthologues of a yeast regulator of nonsense transcript stability.

H A Perlick, S M Medghalchi, F A Spencer, R J Kendzior, Jr, H C Dietz

Proc Natl Acad Sci U S A. 1996 Oct 1; 93(20): 10928–10932. doi: 10.1073/pnas.93.20.10928

PMCID:: PMC38260

Summary Page Browse PDF–1.1M

Select item 940162013.

RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis

Baomei Qian, Yang Li, Ruoyu Yan, Shenglin Han, Zhiwen Bu, Jie Gong, Bangjin Zheng, Zihan Yuan, Sen Ren, Qing He, Jinwen Zhang, Chen Xu, Ruilin Wang, Zheng Sun, Mingyan Lin, Jian Zhou, Lan Ye

Sci Adv. 2022 Aug; 8(34): eabq2945. Published online 2022 Aug 24. doi: 10.1126/sciadv.abq2945

PMCID:: PMC9401620

Article PDF–1.9M

Select item 147904814.

Nuclear mRNA Degradation Pathway(s) Are Implicated in Xist Regulation and X Chromosome Inactivation

Constance Ciaudo, Agnès Bourdet, Michel Cohen-Tannoudji, Harry C Dietz, Claire Rougeulle, Philip Avner

PLoS Genet. 2006 Jun; 2(6): e94. Published online 2006 Jun 16. doi: 10.1371/journal.pgen.0020094

PMCID:: PMC1479048

Article PDF–592K

Select item 596432215.

The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts

Frederick Rehfeld, Daniel Maticzka, Sabine Grosser, Pina Knauff, Murat Eravci, Imre Vida, Rolf Backofen, F. Gregory Wulczyn

Nat Commun. 2018; 9: 1235. Published online 2018 Mar 26. doi: 10.1038/s41467-018-03681-3

PMCID:: PMC5964322

Article PDF–1.7M

Select item 467046016.

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network

Paul A Cassar, Richard L Carpenedo, Payman Samavarchi‐Tehrani, Jonathan B Olsen, Chang Jun Park, Wing Y Chang, Zhaoyi Chen, Chandarong Choey, Sean Delaney, Huishan Guo, Hongbo Guo, R Matthew Tanner, Theodore J Perkins, Scott A Tenenbaum, Andrew Emili, Jeffrey L Wrana, Derrick Gibbings, William L Stanford

EMBO Rep. 2015 Oct; 16(10): 1334–1357. Published online 2015 Aug 11. doi: 10.15252/embr.201540974

PMCID:: PMC4670460

Article PDF–1.9M

Select item 546738917.

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction

Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II

Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076

PMCID:: PMC5467389

Article PDF–3.2M

Select item 723606018.

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell

iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132

PMCID:: PMC7236060

Article PDF–6.1M

Select item 325246519.

Oct4 links multiple epigenetic pathways to the pluripotency network

Junjun Ding, Huilei Xu, Francesco Faiola, Avi Ma'ayan, Jianlong Wang

Cell Res. 2012 Jan; 22(1): 155–167. Published online 2011 Nov 15. doi: 10.1038/cr.2011.179

PMCID:: PMC3252465

Article PDF–2.7M

Select item 626277720.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214