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Select item 103189821.

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action

Lisbeth L. V. Møller, Mona S. Ali, Jonathan Davey, Steffen H. Raun, Nicoline R. Andersen, Jonathan Z. Long, Hongwei Qian, Jacob F. Jeppesen, Carlos Henriquez-Olguin, Emma Frank, Thomas E. Jensen, Kurt Højlund, Jørgen F. P. Wojtaszewski, Joachim Nielsen, Tim T. Chiu, Mark P. Jedrychowski, Paul Gregorevic, Amira Klip, Erik A. Richter, Lykke Sylow

Proc Natl Acad Sci U S A. 2023 Jul 4; 120(27): e2211041120. Published online 2023 Jun 26. doi: 10.1073/pnas.2211041120

PMCID:: PMC10318982

Article PDF–2.5M

Select item 99503792.

RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling

Haixia Zhu, Zongzhuang Wen, Aizhen Zhang, Dongyue Liu, Hongxiang Wang, Yin Cheng, Xing Yang, Yu Xiao, Jianyuan Li, Daqing Sun, Bin Wu, Jiangang Gao

Commun Biol. 2023; 6: 214. Published online 2023 Feb 23. doi: 10.1038/s42003-023-04579-7

PMCID:: PMC9950379

Article PDF–12M

Select item 29030483.

Morphological and proliferative abnormalities in renal mesangial cells lacking RhoGDI

Heike Bielek, Anthony Anselmo, Celine DerMardirossian

Cell Signal. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Cell Signal. 2009 Dec; 21(12): 1974–1983. Published online 2009 Sep 15. doi: 10.1016/j.cellsig.2009.09.008

PMCID:: PMC2903048

Article PDF–1.8M

Select item 81066404.

The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules

Chinyere Agbaegbu Iweka, Rowan K. Hussein, Panpan Yu, Yasuhiro Katagiri, Herbert M Geller

J Neurochem. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: J Neurochem. 2021 May; 157(3): 494–507. Published online 2021 Jan 3. doi: 10.1111/jnc.15271

PMCID:: PMC8106640

Article PDF–2.0M

Select item 24949375.

Dissociation of Rac1(GDP)·RhoGDI Complexes by the Cooperative Action of Anionic Liposomes Containing Phosphatidylinositol 3,4,5-Trisphosphate, Rac Guanine Nucleotide Exchange Factor, and GTP

Yelena Ugolev, Yevgeny Berdichevsky, Carolyn Weinbaum, Edgar Pick

J Biol Chem. 2008 Aug 8; 283(32): 22257–22271. doi: 10.1074/jbc.M800734200

PMCID:: PMC2494937

Article PDF–862K

Select item 23646376.

Rho GDP Dissociation Inhibitor-Mediated Disruption of Rho GTPase Activity Impairs Lens Fiber Cell Migration, Elongation and Survival

Rupalatha Maddala, Lixing W. Reneker, Bhavana Pendurthi, Ponugoti V. Rao

Dev Biol. Author manuscript; available in PMC 2009 Mar 1.

Published in final edited form as: Dev Biol. 2008 Mar 1; 315(1): 217–231. Published online 2008 Jan 3. doi: 10.1016/j.ydbio.2007.12.039

PMCID:: PMC2364637

Article PDF–5.6M

Select item 49052617.

Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes

David Auguste, Mirela Maier, Cindy Baldwin, Lamine Aoudjit, Richard Robins, Indra R. Gupta, Tomoko Takano

Small GTPases. 2016 Apr-Jun; 7(2): 107–121. Published online 2016 Jan 4. doi: 10.1080/21541248.2015.1113353

PMCID:: PMC4905261

Article PDF–1.2M

Select item 43727048.

Protein Tyrosine Phosphatase-PEST and β8 Integrin Regulate Spatiotemporal Patterns of RhoGDI1 Activation in Migrating Cells

Hye Shin Lee, Mujeeburahiman Cheerathodi, Sankar P. Chaki, Steve B. Reyes, Yanhua Zheng, Zhimin Lu, Helena Paidassi, Celine DerMardirossian, Adam Lacy-Hulbert, Gonzalo M. Rivera, Joseph H. McCarty

Mol Cell Biol. 2015 Apr; 35(8): 1401–1413. Prepublished online 2015 Feb 9. Published online 2015 Mar 24. doi: 10.1128/MCB.00112-15

PMCID:: PMC4372704

Article PDF–3.1M

Select item 40976709.

14-3-3τ Promotes Breast Cancer Invasion and Metastasis by Inhibiting RhoGDIα

Yang Xiao, Vivian Y. Lin, Shi Ke, Gregory E. Lin, Fang-Tsyr Lin, Weei-Chin Lin

Mol Cell Biol. 2014 Jul; 34(14): 2635–2649. doi: 10.1128/MCB.00076-14

Correction in:: Mol Cell Biol. 2014 Aug; 34(16): 3180.

PMCID:: PMC4097670

Article PDF–4.4M

Select item 367903610.

Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling

Maria Eugenia Sabbatini, John A. Williams

PLoS One. 2013; 8(6): e66029. Published online 2013 Jun 11. doi: 10.1371/journal.pone.0066029

PMCID:: PMC3679036

Article PDF–2.2M

Select item 329886611.

Cognitive impairment in Gdi1-deficient mice is associated with altered synaptic vesicle pools and short-term synaptic plasticity, and can be corrected by appropriate learning training

Veronica Bianchi, Pasqualina Farisello, Pietro Baldelli, Virginia Meskenaite, Marco Milanese, Matteo Vecellio, Sven Mühlemann, Hans Peter Lipp, Giambattista Bonanno, Fabio Benfenati, Daniela Toniolo, Patrizia D'Adamo

Hum Mol Genet. 2009 Jan 1; 18(1): 105–117. Published online 2008 Oct 1. doi: 10.1093/hmg/ddn321

PMCID:: PMC3298866

Article PDF–808K

Select item 314872312.

Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor–dependent pathway

Shigeru Shibata, ShengYu Mu, Hiroo Kawarazaki, Kazuhiko Muraoka, Ken-ichi Ishizawa, Shigetaka Yoshida, Wakako Kawarazaki, Maki Takeuchi, Nobuhiro Ayuzawa, Jun Miyoshi, Yoshimi Takai, Akira Ishikawa, Tatsuo Shimosawa, Katsuyuki Ando, Miki Nagase, Toshiro Fujita

J Clin Invest. 2011 Aug 1; 121(8): 3233–3243. Published online 2011 Jul 18. doi: 10.1172/JCI43124

PMCID:: PMC3148723

Article PDF–1.4M

Select item 282541413.

Differential Phosphorylation of RhoGDI Mediates the Distinct Cycling of Cdc42 and Rac1 to Regulate Second-phase Insulin Secretion

Zhanxiang Wang, Debbie C. Thurmond

J Biol Chem. 2010 Feb 26; 285(9): 6186–6197. Published online 2009 Dec 22. doi: 10.1074/jbc.M109.072421

PMCID:: PMC2825414

Article PDF–1.3M

Select item 419251414.

Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

Tengis S. Pavlov, Vladislav Levchenko, Alexander Staruschenko

J Biol Chem. 2014 Oct 10; 289(41): 28651–28659. Published online 2014 Aug 27. doi: 10.1074/jbc.M114.558262

PMCID:: PMC4192514

Article PDF–2.0M

Select item 268341515.

Effective Use of PI3K and MEK Inhibitors to Treat Mutant K-Ras G12D and PIK3CA H1047R Murine Lung Cancers

Jeffrey A. Engelman, Liang Chen, Xiaohong Tan, Katherine Crosby, Alexander R. Guimaraes, Rabi Upadhyay, Michel Maira, Kate McNamara, Samanthi A. Perera, Youngchul Song, Lucian R. Chirieac, Ramneet Kaur, Angela Lightbown, Jessica Simendinger, Timothy Li, Robert F. Padera, Carlos García-Echeverría, Ralph Weissleder, Umar Mahmood, Lewis C. Cantley, Kwok-Kin Wong

Nat Med. Author manuscript; available in PMC 2009 Jun 1.

Published in final edited form as: Nat Med. 2008 Dec; 14(12): 1351–1356. Published online 2008 Nov 30. doi: 10.1038/nm.1890