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Select item 109527001.

CD45 limits early Natural Killer cell development

Lizeth G Meza Guzman, Craig D Hyland, Grace M Bidgood, Evelyn Leong, Zihan Shen, Wilford Goh, Jai Rautela, James E Vince, Sandra E Nicholson, Nicholas D Huntington

Immunol Cell Biol. 2024 Jan; 102(1): 58–70. Published online 2023 Oct 19. doi: 10.1111/imcb.12701

PMCID:: PMC10952700

Article PDF–2.2M

Select item 106954112.

CD45.1/CD45.2 Congenic Markers Induce a Selective Bias for CD8⁺ T Cells during Adoptive Lymphocyte Reconstitution in Lymphocytopenia Mice

Rakhee Rathnam Kalari Kandy, Xiaoxuan Fan, Xuefang Cao

Immunohorizons. 2023 Nov; 7(11): 755–759. Published online 2023 Nov 8. doi: 10.4049/immunohorizons.2300014

PMCID:: PMC10695411

Article PDF–1.0M

Select item 106504923.

Murine Bone Marrow Erythroid Cells Have Two Branches of Differentiation Defined by the Presence of CD45 and a Different Immune Transcriptome Than Fetal Liver Erythroid Cells

Olga Perik-Zavodskaia, Roman Perik-Zavodskii, Kirill Nazarov, Marina Volynets, Saleh Alrhmoun, Julia Shevchenko, Sergey Sennikov

Int J Mol Sci. 2023 Nov; 24(21): 15752. Published online 2023 Oct 30. doi: 10.3390/ijms242115752

PMCID:: PMC10650492

Article PDF–9.0M

Select item 104836384.

CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s

Guangwei Cui, Akihiro Shimba, Jianshi Jin, Nozomi Hojo, Takuma Asahi, Shinya Abe, Aki Ejima, Shinri Okada, Keizo Ohira, Ryoma Kato, Shizue Tani-ichi, Ryo Yamada, Takashi Ebihara, Katsuyuki Shiroguchi, Koichi Ikuta

Proc Natl Acad Sci U S A. 2023 Sep 5; 120(36): e2215941120. Published online 2023 Aug 28. doi: 10.1073/pnas.2215941120

PMCID:: PMC10483638

Article PDF–7.7M

Select item 93150505.

An autoimmune stem-like CD8 T cell population drives type 1 diabetes

Sofia V. Gearty, Friederike Dündar, Paul Zumbo, Gabriel Espinosa-Carrasco, Mojdeh Shakiba, Francisco J. Sanchez-Rivera, Nicholas D. Socci, Prerak Trivedi, Scott W. Lowe, Peter Lauer, Neeman Mohibullah, Agnes Viale, Teresa P. DiLorenzo, Doron Betel, Andrea Schietinger

Nature. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Nature. 2022 Feb; 602(7895): 156–161. Published online 2021 Nov 30. doi: 10.1038/s41586-021-04248-x

PMCID:: PMC9315050

Article PDF–5.6M

Select item 84356646.

Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity

Peter Szodoray, Tor Kristian Andersen, Julia Heinzelbecker, John F. Imbery, Peter C. Huszthy, Stephanie M. Stanford, Bjarne Bogen, Ole B. Landsverk, Nunzio Bottini, Anders Tveita, Ludvig A. Munthe, Britt Nakken

Cell Rep. Author manuscript; available in PMC 2021 Sep 13.

Published in final edited form as: Cell Rep. 2021 Aug 10; 36(6): 109525. doi: 10.1016/j.celrep.2021.109525

PMCID:: PMC8435664

Article PDF–2.4M

Select item 53231167.

CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts

Laetitia Saint-Paul, Chi-Hung Nguyen, Anne Buffière, Jean-Paul Pais de Barros, Arlette Hammann, Corinne Landras-Guetta, Rodolphe Filomenko, Marie-Lorraine Chrétien, Pauline Johnson, Jean-Noël Bastie, Laurent Delva, Ronan Quéré

Oncotarget. 2016 Oct 4; 7(40): 64785–64797. Published online 2016 Aug 25. doi: 10.18632/oncotarget.11622

PMCID:: PMC5323116

Article PDF–1.7M

Select item 50813948.

A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire

Susanne G. Oberle, Layane Hanna-El-Daher, Vijaykumar Chennupati, Sarah Enouz, Stefanie Scherer, Martin Prlic, Dietmar Zehn

Cell Rep. 2016 Oct 11; 17(3): 627–635. Published online 2016 Oct 11. doi: 10.1016/j.celrep.2016.09.072

PMCID:: PMC5081394

Article

Select item 49114929.

Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1^STEM Mouse

Francois E. Mercier, David B. Sykes, David T. Scadden

Stem Cell Reports. 2016 Jun 14; 6(6): 985–992. Published online 2016 May 12. doi: 10.1016/j.stemcr.2016.04.010

PMCID:: PMC4911492

Article PDF–1.0M

Select item 472923610.

Differential Requirements for IL-17A and IL-22 in Cecal versus Colonic Inflammation Induced by Helicobacter hepaticus

Peter J. Morrison, Sarah J. Ballantyne, Sandy J. Macdonald, John W.J. Moore, David Jenkins, Jill F. Wright, Lynette A. Fouser, Marika C. Kullberg

Am J Pathol. 2015 Dec; 185(12): 3290–3303. doi: 10.1016/j.ajpath.2015.08.015

PMCID:: PMC4729236

Article PDF–2.0M

Select item 382257711.

Differential Representation of B Cell Subsets in Mixed Bone Marrow Chimera Mice Due to Expression of Allelic Variants of CD45 (CD45.1/CD45.2)

Sreemanti Basu, Avijit Ray, Bonnie N. Dittel

J Immunol Methods. Author manuscript; available in PMC 2014 Oct 31.

Published in final edited form as: J Immunol Methods. 2013 Oct 31; 396(0): 10.1016/j.jim.2013.07.008. Published online 2013 Aug 6. doi: 10.1016/j.jim.2013.07.008

PMCID:: PMC3822577

Article PDF–1019K

Select item 377188912.

Genome-Wide Mouse Mutagenesis Reveals CD45-Mediated T Cell Function as Critical in Protective Immunity to HSV-1

Grégory Caignard, Gabriel A. Leiva-Torres, Michael Leney-Greene, Benoit Charbonneau, Anne Dumaine, Nassima Fodil-Cornu, Michal Pyzik, Pablo Cingolani, Jeremy Schwartzentruber, Jeremy Dupaul-Chicoine, Huaijian Guo, Maya Saleh, André Veillette, Marc Lathrop, Mathieu Blanchette, Jacek Majewski, Angela Pearson, Silvia M. Vidal

PLoS Pathog. 2013 Sep; 9(9): e1003637. Published online 2013 Sep 12. doi: 10.1371/journal.ppat.1003637

PMCID:: PMC3771889

Article PDF–1.8M

Select item 343837513.

Endogenous antigen tunes the responsiveness of naive B cells but not T cells

Julie Zikherman, Ramya Parameswaran, Arthur Weiss

Nature. Author manuscript; available in PMC 2013 Mar 6.

Published in final edited form as: Nature. 2012 Sep 6; 489(7414): 160–164. doi: 10.1038/nature11311

PMCID:: PMC3438375

Article PDF–1.2M

Select item 325295614.

Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival

Julie Zikherman, Kristin Doan, Ramya Parameswaran, William Raschke, Arthur Weiss

Proc Natl Acad Sci U S A. 2012 Jan 3; 109(1): E3–E12. Published online 2011 Nov 30. doi: 10.1073/pnas.1117374108

PMCID:: PMC3252956

Article PDF–1.3M

Select item 306819315.

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice

Yuyan Zhu, Huayan Hou, Kavon Rezai-Zadeh, Brian Giunta, Amanda Ruscin, Carmelina Gemma, JingJi Jin, Natasa Dragicevic, Patrick Bradshaw, Suhail Rasool, Charles G. Glabe, Jared Ehrhart, Paula Bickford, Takashi Mori, Demian Obregon, Terrence Town, Jun Tan

J Neurosci. 2011 Jan 26; 31(4): 1355–1365. doi: 10.1523/JNEUROSCI.3268-10.2011

PMCID:: PMC3068193

Article PDF–1.6M

Select item 293906416.

Role of CD45 Signaling Pathway in Galactoxylomannan-Induced T Cell Damage

Eva Pericolini, Elena Gabrielli, Giovanni Bistoni, Elio Cenci, Stefano Perito, Siu-Kei Chow, Francesca Riuzzi, Rosario Donato, Arturo Casadevall, Anna Vecchiarelli

PLoS One. 2010; 5(9): e12720. Published online 2010 Sep 14. doi: 10.1371/journal.pone.0012720

PMCID:: PMC2939064

Article PDF–1.9M

Select item 268597917.

A Non-Cytosolic Protein of Trypanosoma evansi Induces CD45-Dependent Lymphocyte Death

Nicolas Antoine-Moussiaux, Anne Cornet, François Cornet, Stéphanie Glineur, Martin Dermine, Daniel Desmecht

PLoS One. 2009; 4(5): e5728. Published online 2009 May 29. doi: 10.1371/journal.pone.0005728

PMCID:: PMC2685979

Article PDF–868K

Select item 267601818.

Reduced Expression of CD45 Protein-tyrosine Phosphatase Provides Protection against Anthrax Pathogenesis

Rekha G. Panchal, Ricky L. Ulrich, Steven B. Bradfute, Douglas Lane, Gordon Ruthel, Tara A. Kenny, Patrick L. Iversen, Arthur O. Anderson, Rick Gussio, William C. Raschke, Sina Bavari

J Biol Chem. 2009 May 8; 284(19): 12874–12885. doi: 10.1074/jbc.M809633200

PMCID:: PMC2676018

Article PDF–916K

Select item 267195919.

Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase During Thymocyte Development

Rustom Falahati, David Leitenberg

J Immunol. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: J Immunol. 2008 Nov 1; 181(9): 6082–6091. doi: 10.4049/jimmunol.181.9.6082

PMCID:: PMC2671959

Article PDF–1.8M

Select item 262674020.

Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses

Michelle L. Hermiston, Julie Zikherman, Allison L. Tan, Viola C. Lam, Nicole M. Cresalia, Nir Oksenberg, Nira Goren, David Brassat, Jorge R. Oksenberg, Arthur Weiss

Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2): 546–551. Published online 2009 Jan 7. doi: 10.1073/pnas.0811647106