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Select item 76869151.

Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Shashank Shekhar, Gregory J. Hoeprich, Jeff Gelles, Bruce L. Goode

J Cell Biol. 2021 Jan 4; 220(1): e202006022. Published online 2020 Nov 23. doi: 10.1083/jcb.202006022

PMCID:: PMC7686915

Article PDF–2.7M

Select item 72525392.

Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1

Isabelle C. Becker, Inga Scheller, Lou M. Wackerbarth, Sarah Beck, Tobias Heib, Katja Aurbach, Georgi Manukjan, Carina Gross, Markus Spindler, Zoltan Nagy, Walter Witke, Pekka Lappalainen, Markus Bender, Harald Schulze, Irina Pleines, Bernhard Nieswandt

Blood Adv. 2020 May 26; 4(10): 2124–2134. Published online 2020 May 14. doi: 10.1182/bloodadvances.2019001303

PMCID:: PMC7252539

Article PDF–2.0M

Select item 58801223.

Molecular mechanism for inhibition of twinfilin by phosphoinositides

Markku Hakala, Maria Kalimeri, Giray Enkavi, Ilpo Vattulainen, Pekka Lappalainen

J Biol Chem. 2018 Mar 30; 293(13): 4818–4829. Published online 2018 Feb 7. doi: 10.1074/jbc.RA117.000484

PMCID:: PMC5880122

Article PDF–1.5M

Select item 24478954.

Structure of the actin-depolymerizing factor homology domain in complex with actin

Ville O. Paavilainen, Esko Oksanen, Adrian Goldman, Pekka Lappalainen

J Cell Biol. 2008 Jul 14; 182(1): 51–59. doi: 10.1083/jcb.200803100

PMCID:: PMC2447895

Article PDF–3.0M

Select item 18055825.

Structural basis and evolutionary origin of actin filament capping by twinfilin

Ville O. Paavilainen, Maarit Hellman, Emmanuèle Helfer, Miia Bovellan, Arto Annila, Marie-France Carlier, Perttu Permi, Pekka Lappalainen

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3113–3118. Published online 2007 Feb 20. doi: 10.1073/pnas.0608725104

PMCID:: PMC1805582

Article PDF–3.1M

Select item 62490026.

A novel mode of capping protein-regulation by twinfilin

Adam B Johnston, Denise M Hilton, Patrick McConnell, Britney Johnson, Meghan T Harris, Avital Simone, Gaya K Amarasinghe, John A Cooper, Bruce L Goode

eLife. 2018; 7: e41313. Published online 2018 Oct 23. doi: 10.7554/eLife.41313

PMCID:: PMC6249002

Article PDF–5.4M

Select item 39958947.

Fibroblast Growth Factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation

Sarah Utley, David James, Nirmala Mavila, Marie V. Nguyen, Christopher Vendryes, S. Michael Salisbury, Jennifer Phan, Kasper S. Wang

J Hepatol. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Hepatol. 2014 May; 60(5): 1002–1009. Published online 2013 Dec 21. doi: 10.1016/j.jhep.2013.12.017

PMCID:: PMC3995894

Article PDF–2.2M

Select item 14221638.

Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility

Emmanuèle Helfer, Elisa M Nevalainen, Perttu Naumanen, Stéphane Romero, Dominique Didry, Dominique Pantaloni, Pekka Lappalainen, Marie-France Carlier

EMBO J. 2006 Mar 22; 25(6): 1184–1195. Published online 2006 Mar 2. doi: 10.1038/sj.emboj.7601019

PMCID:: PMC1422163

Article PDF–583K

Select item 853599.

Mouse A6/Twinfilin Is an Actin Monomer-Binding Protein That Localizes to the Regions of Rapid Actin Dynamics

Maria Vartiainen, Pauli J. Ojala, Petri Auvinen, Johan Peränen, Pekka Lappalainen

Mol Cell Biol. 2000 Mar; 20(5): 1772–1783. doi: 10.1128/mcb.20.5.1772-1783.2000

PMCID:: PMC85359

Article PDF–2.3M

Select item 51492710.

Biological role and structural mechanism of twinfilin–capping protein interaction

Sandra Falck, Ville O Paavilainen, Martin A Wear, J Günter Grossmann, John A Cooper, Pekka Lappalainen

EMBO J. 2004 Aug 4; 23(15): 3010–3019. Published online 2004 Jul 29. doi: 10.1038/sj.emboj.7600310

PMCID:: PMC514927

Article PDF–452K

Select item 219883111.

Interactions with PIP₂, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin

Sandra Palmgren, Pauli J. Ojala, Martin A. Wear, John A. Cooper, Pekka Lappalainen

J Cell Biol. 2001 Oct 15; 155(2): 251–260. doi: 10.1083/jcb.200106157

PMCID:: PMC2198831

Article PDF–204K

Select item 374561012.

Molecular Characterization of Mutant Mouse Strains Generated from the EUCOMM/KOMP-CSD ES Cell Resource

Edward Ryder, Diane Gleeson, Debarati Sethi, Sapna Vyas, Evelina Miklejewska, Priya Dalvi, Bishoy Habib, Ross Cook, Matthew Hardy, Kalpesh Jhaveri, Joanna Bottomley, Hannah Wardle-Jones, James N. Bussell, Richard Houghton, Jennifer Salisbury, William C. Skarnes, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis

Mamm Genome. 2013; 24(7): 286–294. Published online 2013 Aug 4. doi: 10.1007/s00335-013-9467-x

PMCID:: PMC3745610

Article PDF–353K

Select item 433099913.

Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers

Kostas C Nikolaou, Panagiotis Moulos, George Chalepakis, Pantelis Hatzis, Hisanobu Oda, Danny Reinberg, Iannis Talianidis

EMBO J. 2015 Feb 12; 34(4): 430–447. Published online 2014 Dec 16. doi: 10.15252/embj.201489279

PMCID:: PMC4330999

Article PDF–4.8M

Select item 626277714.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Article

Select item 312173515.

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang, Catalin Barbacioru, Ellen Nordman, Siqin Bao, Caroline Lee, Xiaohui Wang, Brian B. Tuch, Edith Heard, Kaiqin Lao, M. Azim Surani

PLoS One. 2011; 6(6): e21208. Published online 2011 Jun 23. doi: 10.1371/journal.pone.0021208

PMCID:: PMC3121735

Article PDF–1.0M

Select item 624418316.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Article PDF–753K

Select item 564508217.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Article PDF–2.3M

Select item 43978318.

Genomic Analysis of Mouse Retinal Development

Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko

PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247

PMCID:: PMC439783

Article PDF–975K

Select item 645951019.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Article PDF–5.1M

Select item 633346020.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327