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Select item 87457201.

Protective Effect of Low-Dose Alcohol Consumption against Post-Ischemic Neuronal Apoptosis: Role of L-PGDS

Chun Li, Jiyu Li, Ethyn G. Loreno, Sumitra Miriyala, Manikandan Panchatcharam, Hong Sun

Int J Mol Sci. 2022 Jan; 23(1): 133. Published online 2021 Dec 23. doi: 10.3390/ijms23010133

PMCID:: PMC8745720

Article PDF–5.2M

Select item 78034832.

L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis

Yassine Ouhaddi, Mehdi Najar, Frédéric Paré, Bertrand Lussier, Yoshihiro Urade, Mohamed Benderdour, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi

Aging (Albany NY) 2020 Dec 31; 12(24): 24778–24797. Published online 2020 Dec 23. doi: 10.18632/aging.202367

PMCID:: PMC7803483

Article PDF–1.9M

Select item 63744613.

L-PGDS-produced PGD₂ in premature, but not in mature, adipocytes increases obesity and insulin resistance

Ko Fujimori, Kosuke Aritake, Yo Oishi, Nanae Nagata, Toko Maehara, Michael Lazarus, Yoshihiro Urade

Sci Rep. 2019; 9: 1931. Published online 2019 Feb 13. doi: 10.1038/s41598-018-38453-y

PMCID:: PMC6374461

Article PDF–1.8M

Select item 31493404.

Selenoprotein-dependent Up-regulation of Hematopoietic Prostaglandin D₂ Synthase in Macrophages Is Mediated through the Activation of Peroxisome Proliferator-activated Receptor (PPAR) γ

Ujjawal H. Gandhi, Naveen Kaushal, Kodihalli C. Ravindra, Shailaja Hegde, Shakira M. Nelson, Vivek Narayan, Hema Vunta, Robert F. Paulson, K. Sandeep Prabhu

J Biol Chem. 2011 Aug 5; 286(31): 27471–27482. Published online 2011 Jun 13. doi: 10.1074/jbc.M111.260547

PMCID:: PMC3149340

Article PDF–1.8M

Select item 27559575.

Structural Basis of the Catalytic Mechanism Operating in Open-Closed Conformers of Lipocalin Type Prostaglandin D Synthase

Takashi Kumasaka, Kosuke Aritake, Hideo Ago, Daisuke Irikura, Toshiharu Tsurumura, Masaki Yamamoto, Masashi Miyano, Yoshihiro Urade, Osamu Hayaishi

J Biol Chem. 2009 Aug 14; 284(33): 22344–22352. Published online 2009 Jun 22. doi: 10.1074/jbc.M109.018341

PMCID:: PMC2755957

Article PDF–2.3M

Select item 27135786.

Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia

Sofiyan Saleem, Zahoor A. Shah, Yoshihiro Urade, Sylvain Doré

Neuroscience. Author manuscript; available in PMC 2010 Apr 21.

Published in final edited form as: Neuroscience. 2009 Apr 21; 160(1): 248–254. Published online 2009 Feb 28. doi: 10.1016/j.neuroscience.2009.02.039

PMCID:: PMC2713578

Article PDF–2.0M

Select item 2999587.

Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behavior

Jessica A. Mong, Nino Devidze, Andrew Goodwillie, Donald W. Pfaff

Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25): 15206–15211. Published online 2003 Nov 24. doi: 10.1073/pnas.2436540100

PMCID:: PMC299958

Article PDF–426K

Select item 1409648.

Estradiol differentially regulates lipocalin-type prostaglandin D synthase transcript levels in the rodent brain: Evidence from high-density oligonucleotide arrays and in situ hybridization

Jessica A. Mong, Nino Devidze, Donald E. Frail, Lawrence T. O'Connor, Manjo Samuel, Elena Choleris, Sonoko Ogawa, Donald W. Pfaff

Proc Natl Acad Sci U S A. 2003 Jan 7; 100(1): 318–323. Published online 2002 Dec 23. doi: 10.1073/pnas.262663799

PMCID:: PMC140964

Article PDF–426K

Select item 152049.

Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice

Naomi Eguchi, Toshiaki Minami, Naoki Shirafuji, Yoshihide Kanaoka, Takashi Tanaka, Akihisa Nagata, Nobuaki Yoshida, Yoshihiro Urade, Seiji Ito, Osamu Hayaishi

Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2): 726–730. doi: 10.1073/pnas.96.2.726

PMCID:: PMC15204

Article PDF–193K

Select item 675774810.

Perineuronal Oligodendrocytes Protect against Neuronal Apoptosis through the Production of Lipocalin-Type Prostaglandin D Synthase in a Genetic Demyelinating Model

Masako Taniike, Ikuko Mohri, Naomi Eguchi, Carsten T. Beuckmann, Kinuko Suzuki, Yoshihiro Urade

J Neurosci. 2002 Jun 15; 22(12): 4885–4896. doi: 10.1523/JNEUROSCI.22-12-04885.2002

PMCID:: PMC6757748

Article PDF–1.9M

Select item 366910711.

H-rev107 regulates prostaglandin D2 synthase-mediated suppression of cellular invasion in testicular cancer cells

Rong-Yaun Shyu, Chang-Chieh Wu, Chun-Hua Wang, Tzung-Chieh Tsai, Lu-Kai Wang, Mao-Liang Chen, Shun-Yuan Jiang, Fu-Ming Tsai

J Biomed Sci. 2013; 20(1): 30. Published online 2013 May 20. doi: 10.1186/1423-0127-20-30

PMCID:: PMC3669107

Article PDF–1.3M

Select item 339031512.

Lipocalin Prostaglandin D Synthase and PPARγ2 Coordinate to Regulate Carbohydrate and Lipid Metabolism In Vivo

Sam Virtue, Mojgan Masoodi, Vidya Velagapudi, Chong Yew Tan, Martin Dale, Tapani Suorti, Marc Slawik, Margaret Blount, Keith Burling, Mark Campbell, Naomi Eguchi, Gema Medina-Gomez, Jaswinder K. Sethi, Matej Orešič, Yoshihiro Urade, Julian L. Griffin, Antonio Vidal-Puig

PLoS One. 2012; 7(7): e39512. Published online 2012 Jul 5. doi: 10.1371/journal.pone.0039512

PMCID:: PMC3390315

Article PDF–1.0M

Select item 330880513.

Lipocalin-type Prostaglandin D₂ Synthase Protein Regulates Glial Cell Migration and Morphology through Myristoylated Alanine-rich C-Kinase Substrate: PROSTAGLANDIN D₂-INDEPENDENT EFFECTS

Shinrye Lee, Eunha Jang, Jong-Heon Kim, Jae-Hong Kim, Won-Ha Lee, Kyoungho Suk

J Biol Chem. 2012 Mar 16; 287(12): 9414–9428. Published online 2012 Jan 24. doi: 10.1074/jbc.M111.330662

PMCID:: PMC3308805

Article PDF–4.7M

Select item 268911714.

Glucocorticoid protects rodent hearts from ischemia/reperfusion injury by activating lipocalin-type prostaglandin D synthase–derived PGD₂ biosynthesis

Satori Tokudome, Motoaki Sano, Ken Shinmura, Tomohiro Matsuhashi, Shintaro Morizane, Hidenori Moriyama, Kayoko Tamaki, Kentaro Hayashida, Hiroki Nakanishi, Noritada Yoshikawa, Noriaki Shimizu, Jin Endo, Takaharu Katayama, Mitsushige Murata, Shinsuke Yuasa, Ruri Kaneda, Kengo Tomita, Naomi Eguchi, Yoshihiro Urade, Koichiro Asano, Yasunori Utsunomiya, Takeshi Suzuki, Ryo Taguchi, Hirotoshi Tanaka, Keiichi Fukuda

J Clin Invest. 2009 Jun 1; 119(6): 1477–1488. Published online 2009 May 18. doi: 10.1172/JCI37413

PMCID:: PMC2689117

Article PDF–2.8M

Select item 267126215.

Inhibition of Prostaglandin D Synthase Suppresses Muscular Necrosis

Ikuko Mohri, Kosuke Aritake, Hidetoshi Taniguchi, Yo Sato, Shinya Kamauchi, Nanae Nagata, Toshihiko Maruyama, Masako Taniike, Yoshihiro Urade

Am J Pathol. 2009 May; 174(5): 1735–1744. doi: 10.2353/ajpath.2009.080709

PMCID:: PMC2671262

Article PDF–2.5M

Select item 265805616.

Biochemical, Functional, and Pharmacological Characterization of AT-56, an Orally Active and Selective Inhibitor of Lipocalin-type Prostaglandin D Synthase

Daisuke Irikura, Kosuke Aritake, Nanae Nagata, Toshihiko Maruyama, Shigeru Shimamoto, Yoshihiro Urade

J Biol Chem. 2009 Mar 20; 284(12): 7623–7630. doi: 10.1074/jbc.M808593200

PMCID:: PMC2658056

Article PDF–610K

Select item 240925217.

Hematopoietic prostaglandin D₂ synthase controls the onset and resolution of acute inflammation through PGD₂ and 15-deoxyΔ^12–14 PGJ₂

Ravindra Rajakariar, Mark Hilliard, Toby Lawrence, Seema Trivedi, Paul Colville-Nash, Geoff Bellingan, Desmond Fitzgerald, Muhammad M. Yaqoob, Derek W. Gilroy

Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52): 20979–20984. Published online 2007 Dec 5. doi: 10.1073/pnas.0707394104

PMCID:: PMC2409252

Article PDF–447K

Select item 185103518.

Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

Takahisa Kanekiyo, Tadato Ban, Kosuke Aritake, Zhi-Li Huang, Wei-Min Qu, Issay Okazaki, Ikuko Mohri, Shigeo Murayama, Keiichi Ozono, Masako Taniike, Yuji Goto, Yoshihiro Urade

Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15): 6412–6417. Published online 2007 Apr 2. doi: 10.1073/pnas.0701585104

PMCID:: PMC1851035

Article PDF–2.1M

Select item 4929419.

Structural organization of the gene for prostaglandin D synthase in the rat brain.

M Igarashi, A Nagata, H Toh, Y Urade, O Hayaishi

Proc Natl Acad Sci U S A. 1992 Jun 15; 89(12): 5376–5380. doi: 10.1073/pnas.89.12.5376

PMCID:: PMC49294

Summary Page Browse PDF–1.3M

Select item 815799220.

TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures

Tongfei A. Wang, Chao Chen, Fen Huang, Shengjie Feng, Jason Tien, João M. Braz, Allan I. Basbaum, Yuh Nung Jan, Lily Yeh Jan

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2023342118. Published online 2021 May 10. doi: 10.1073/pnas.2023342118

PMCID:: PMC8157992

Article PDF–1.8M

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