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Select item 80088011.

Endothelial Cell Protein C Receptor Deficiency Attenuates Streptococcus pneumoniae–induced Pleural Fibrosis

Shiva Keshava, Jhansi Magisetty, Torry A. Tucker, Weshely Kujur, Sachin Mulik, Charles T. Esmon, Steven Idell, L. Vijaya Mohan Rao, Usha R. Pendurthi

Am J Respir Cell Mol Biol. 2021 Apr; 64(4): 477–491. doi: 10.1165/rcmb.2020-0328OC

PMCID:: PMC8008801

Article PDF–3.6M

Select item 78262622.

Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model

Yu-Han Hung, Sha Huang, Michael K Dame, Qianhui Yu, Qing C Yu, Yi A Zeng, J Gray Camp, Jason R Spence, Praveen Sethupathy

Nucleic Acids Res. 2021 Jan 25; 49(2): 726–744. Published online 2021 Jan 6. doi: 10.1093/nar/gkaa1204

PMCID:: PMC7826262

Article PDF–6.4M

Select item 76895043.

A critical role of endothelial cell protein C receptor in the intestinal homeostasis in experimental colitis

Vijay Kondreddy, Shiva Keshava, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao

Sci Rep. 2020; 10: 20569. Published online 2020 Nov 25. doi: 10.1038/s41598-020-77502-3

PMCID:: PMC7689504

Article PDF–3.3M

Select item 76737074.

The endothelial protein C receptor plays an essential role in the maintenance of pregnancy

Michelle M. Castillo, Qiuhui Yang, Abril Solis Sigala, Dosia T. McKinney, Min Zhan, Kristen L. Chen, Jason A. Jarzembowski, Rashmi Sood

Sci Adv. 2020 Nov; 6(45): eabb6196. Published online 2020 Nov 6. doi: 10.1126/sciadv.abb6196

PMCID:: PMC7673707

Article PDF–1.6M

Select item 41334885.

The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo

Giulia Pavani, Lacramioara Ivanciu, Armida Faella, Oscar A. Marcos-Contreras, Paris Margaritis

Blood. 2014 Aug 14; 124(7): 1157–1165. Prepublished online 2014 Jun 23. doi: 10.1182/blood-2014-04-567297

PMCID:: PMC4133488

Article

Select item 37353656.

Organ-specific protection against LPS-induced vascular leak is dependent on the endothelial protein C receptor (EPCR)

Annette von Drygalski, Christian Furlan-Freguia, Wolfram Ruf, John H. Griffin, Laurent O. Mosnier

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Apr; 33(4): 769–776. Published online 2013 Feb 7. doi: 10.1161/ATVBAHA.112.301082

PMCID:: PMC3735365

Article PDF–2.4M

Select item 36218877.

Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development

Florence Schaffner, Naho Yokota, Tatiana Carneiro-Lobo, Maki Kitano, Michael Schaffer, G. Mark Anderson, Barbara M. Mueller, Charles T. Esmon, Wolfram Ruf

PLoS One. 2013; 8(4): e61071. Published online 2013 Apr 9. doi: 10.1371/journal.pone.0061071

PMCID:: PMC3621887

Article PDF–1.8M

Select item 28953158.

Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier

Rashid Deane, Barbra LaRue, Abhay P. Sagare, Francis J. Castellino, Zhihui Zhong, Berislav V. Zlokovic

J Cereb Blood Flow Metab. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: J Cereb Blood Flow Metab. 2009 Jan; 29(1): 25–33. Published online 2008 Oct 8. doi: 10.1038/jcbfm.2008.117

PMCID:: PMC2895315

Article PDF–913K

Select item 108349339.

EPCR deficiency ameliorates inflammatory arthritis in mice by suppressing the activation and migration of T cells and dendritic cells

Meilang Xue, Haiyan Lin, Hai Po Helena Liang, Lara Bereza-Malcolm, Tom Lynch, Premarani Sinnathurai, Hartmut Weiler, Christopher Jackson, Lyn March

Rheumatology (Oxford) 2024 Feb; 63(2): 571–580. Published online 2023 May 25. doi: 10.1093/rheumatology/kead230

PMCID:: PMC10834933

Article PDF–1.4M

Select item 1081632210.

Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model

Meilang Xue, Christopher J. Jackson, Haiyan Lin, Ruilong Zhao, Hai Po H. Liang, Hartmut Weiler, John H. Griffin, Lyn March

Int J Mol Sci. 2024 Jan; 25(2): 1255. Published online 2024 Jan 19. doi: 10.3390/ijms25021255

PMCID:: PMC10816322

Article PDF–8.0M

Select item 731620511.

EPCR deficiency or function-blocking antibody protects against joint bleeding–induced pathology in hemophilia mice

Jhansi Magisetty, Usha R. Pendurthi, Charles T. Esmon, L. Vijaya Mohan Rao

Blood. 2020 Jun 18; 135(25): 2211–2223. Prepublished online 2020 Apr 15. doi: 10.1182/blood.2019003824

PMCID:: PMC7316205

Article

Select item 729997612.

Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces

Adrian Fischer, Tim Koopmans, Pushkar Ramesh, Simon Christ, Maximilian Strunz, Juliane Wannemacher, Michaela Aichler, Annette Feuchtinger, Axel Walch, Meshal Ansari, Fabian J. Theis, Kenji Schorpp, Kamyar Hadian, Philipp-Alexander Neumann, Herbert B. Schiller, Yuval Rinkevich

Nat Commun. 2020; 11: 3068. Published online 2020 Jun 17. doi: 10.1038/s41467-020-16893-3

PMCID:: PMC7299976

Article PDF–6.0M

Select item 693867713.

CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions

Jennifer L. Rabe, Giovanny Hernandez, James S. Chavez, Taylor S. Mills, Claus Nerlov, Eric M. Pietras

Exp Hematol. Author manuscript; available in PMC 2020 Dec 17.

Published in final edited form as: Exp Hematol. 2019 Dec 18 : S0301-472X(19)31135-X. Published online 2019 Dec 18. doi: 10.1016/j.exphem.2019.12.003

PMCID:: PMC6938677

Article PDF–2.5M

Select item 511330814.

Identification of blood vascular endothelial stem cells by the expression of protein C receptor

Qing Cissy Yu, Wenqian Song, Daisong Wang, Yi Arial Zeng

Cell Res. 2016 Oct; 26(10): 1079–1098. Published online 2016 Jul 1. doi: 10.1038/cr.2016.85

PMCID:: PMC5113308

Article PDF–11M

Select item 506822615.

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Yasuhiro Kishi, Takaaki Kondo, Sheng Xiao, Nir Yosef, Jellert Gaublomme, Chuan Wu, Chao Wang, Norio Chihara, Aviv Regev, Nicole Joller, Vijay K. Kuchroo

J Exp Med. 2016 Oct 17; 213(11): 2489–2501. doi: 10.1084/jem.20151118

PMCID:: PMC5068226

Article PDF–2.3M

Select item 448078116.

CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1

Sara E. Vazquez, Matthew A. Inlay, Thomas Serwold

Exp Hematol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Exp Hematol. 2015 Jul; 43(7): 578–585. Published online 2015 Apr 16. doi: 10.1016/j.exphem.2015.04.001

PMCID:: PMC4480781

Article PDF–3.6M

Select item 433508517.

Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation

Peyman Dinarvand, Seyed Mahdi Hassanian, Hartmut Weiler, Alireza R. Rezaie

Blood. 2015 Feb 19; 125(8): 1339–1348. Prepublished online 2015 Jan 9. doi: 10.1182/blood-2014-10-609339

PMCID:: PMC4335085

Article

Select item 408557818.

Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo

J. SUNDARAM, S. KESHAVA, R. GOPALAKRISHNAN, C. T. ESMON, U. R. PENDURTHI, L . V. M. RAO

J Thromb Haemost. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Thromb Haemost. 2014 May; 12(5): 690–700. doi: 10.1111/jth.12532

PMCID:: PMC4085578

Article PDF–1.9M

Select item 388358519.

Influence of endothelial cell protein C receptor on plasma clearance of factor VIIa

R. Gopalakrishnan, U.R. Pendurthi, U. Hedner, H. Agersø, C.T. ESMON, L.V.M. Rao

J Thromb Haemost. Author manuscript; available in PMC 2014 Jan 7.

Published in final edited form as: J Thromb Haemost. 2012 May; 10(5): 10.1111/j.1538-7836.2012.04670.x. doi: 10.1111/j.1538-7836.2012.04670.x

PMCID:: PMC3883585

Article PDF–416K

Select item 276919120.

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

Zhihui Zhong, Hristelina Ilieva, Lee Hallagan, Robert Bell, Itender Singh, Nicole Paquette, Meenakshisundaram Thiyagarajan, Rashid Deane, Jose A. Fernandez, Steven Lane, Anna B. Zlokovic, Todd Liu, John H. Griffin, Nienwen Chow, Francis J. Castellino, Konstantin Stojanovic, Don W. Cleveland, Berislav V. Zlokovic

J Clin Invest. 2009 Nov 2; 119(11): 3437–3449. Published online 2009 Oct 19. doi: 10.1172/JCI38476