PMC Links for Gene (Select 19017) - PMC

Elizabeth A. Novak, Erin C. Crawford, Heather L. Mentrup, Brian D. Griffith, David M. Fletcher, Meredith R. Flanagan, Corinne Schneider, Brian Firek, Matthew B. Rogers, Michael J. Morowitz, Jon D. Piganelli, Qian Wang, Kevin P. Mollen

Front Immunol. 2023; 14: 1231700. Published online 2023 Sep 7. doi: 10.3389/fimmu.2023.1231700

PMCID:: PMC10512956

Article PDF–8.9M

Select item 104836665.

Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α

Laura M. de Smalen, Anastasiya Börsch, Aurel B. Leuchtmann, Jonathan F. Gill, Danilo Ritz, Mihaela Zavolan, Christoph Handschin

Proc Natl Acad Sci U S A. 2023 Sep 5; 120(36): e2302360120. Published online 2023 Aug 28. doi: 10.1073/pnas.2302360120

PMCID:: PMC10483666

Article PDF–1.5M

Select item 102014626.

PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice

Francielly Morena da Silva, Megan E. Rosa-Caldwell, Eleanor R. Schrems, Lauren Martinez, Madeline G. Amos, Seongkyun Lim, Ana Regina Cabrera, Jacob L. Brown, Tyrone A. Washington, Nicholas P. Greene

Appl Physiol Nutr Metab. Author manuscript; available in PMC 2023 May 22.

Published in final edited form as: Appl Physiol Nutr Metab. 2022 Sep 1; 47(9): 933–948. Published online 2022 Jun 14. doi: 10.1139/apnm-2022-0086

PMCID:: PMC10201462

Article PDF–1.4M

Select item 99512707.

PGC-1α Senses the CBC of Pre-mRNA to Dictate the Fate of Promoter-Proximally Paused RNAPII

Xavier Rambout, Hana Cho, Roméo Blanc, Qing Lyu, Joseph M. Miano, Joe V. Chakkalakal, Geoffrey M. Nelson, Hari K. Yalamanchili, Karen Adelman, Lynne E. Maquat

Mol Cell. Author manuscript; available in PMC 2024 Jan 19.

Published in final edited form as: Mol Cell. 2023 Jan 19; 83(2): 186–202.e11. doi: 10.1016/j.molcel.2022.12.022

PMCID:: PMC9951270

Article PDF–3.4M

Select item 96882488.

S-nitrosylated PARIS Leads to the Sequestration of PGC-1α into Insoluble Deposits in Parkinson’s Disease Model

Hanna Kim, Ji-Yeong Lee, Soo Jeong Park, Eunsang Kwag, Jihye Kim, Joo-Ho Shin

Cells. 2022 Nov; 11(22): 3682. Published online 2022 Nov 19. doi: 10.3390/cells11223682

PMCID:: PMC9688248

Article PDF–4.6M

Select item 95305029.

PGC1α overexpression preserves muscle mass and function in cisplatin‐induced cachexia

Joshua R. Huot, Fabrizio Pin, Rohit Chatterjee, Andrea Bonetto

J Cachexia Sarcopenia Muscle. 2022 Oct; 13(5): 2480–2491. Published online 2022 Jul 28. doi: 10.1002/jcsm.13035

PMCID:: PMC9530502

Article PDF–11M

Select item 949677010.

A Role for PGC-1a in the Control of Abnormal Mitochondrial Dynamics in Alzheimer’s Disease

Jia Wang, Wen-Jun Liu, Hou-Zhen Shi, Hong-Ru Zhai, Jin-Jun Qian, Wei-Ning Zhang

Cells. 2022 Sep; 11(18): 2849. Published online 2022 Sep 13. doi: 10.3390/cells11182849

PMCID:: PMC9496770

Article PDF–7.9M

Select item 930018011.

Peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha protects a fibrotic liver from partial hepatectomy‐induced advanced liver injury through regulating cell cycle arrest

Linzhong Zhang, Wei Wang, Lipeng Liu, Yanghao Zhang, Xiuying Zhang

Basic Clin Pharmacol Toxicol. 2022 Feb; 130(2): 254–267. Published online 2021 Dec 16. doi: 10.1111/bcpt.13697

PMCID:: PMC9300180

Article PDF–31M

Select item 923292312.

Regulation of PGC1α downstream of the insulin signaling pathway plays a role in the hepatic proteotoxicity of mutant α1-antitrypsin deficiency variant Z

David A. Rudnick, Jiansheng Huang, Tunda Hidvegi, Andrew S. Chu, Pamela Hale, Admire Munanairi, Dennis J. Dietzen, Paul F. Cliften, Eric Tycksen, Andrew J. Lutkewitte, Brian N. Finck, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter

Gastroenterology. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Gastroenterology. 2022 Jul; 163(1): 270–284. Published online 2022 Mar 15. doi: 10.1053/j.gastro.2022.03.010

PMCID:: PMC9232923

Article PDF–2.5M

Select item 907496513.

PGC-1α deficiency reveals sex-specific links between cardiac energy metabolism and EC-coupling during development of heart failure in mice

Nikolay Naumenko, Maija Mutikainen, Lari Holappa, Jorge L Ruas, Tomi Tuomainen, Pasi Tavi

Cardiovasc Res. 2022 May; 118(6): 1520–1534. Published online 2021 Jun 4. doi: 10.1093/cvr/cvab188

PMCID:: PMC9074965

Article PDF–2.3M

Select item 880398214.

Effect of endurance training and PGC-1α overexpression on calculated lactate production volume during exercise based on blood lactate concentration

Reo Takeda, Yudai Nonaka, Katsuyuki Kakinoki, Shinji Miura, Yutaka Kano, Daisuke Hoshino

Sci Rep. 2022; 12: 1635. Published online 2022 Jan 31. doi: 10.1038/s41598-022-05593-1

PMCID:: PMC8803982

Article PDF–2.0M

Select item 874867715.

PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis

Bo Young Nam, Jong Hyun Jhee, Jimin Park, Seonghun Kim, Gyuri Kim, Jung Tak Park, Tae-Hyun Yoo, Shin-Wook Kang, Je-Wook Yu, Seung Hyeok Han

Cell Death Dis. 2022 Jan; 13(1): 31. Published online 2022 Jan 10. doi: 10.1038/s41419-021-04480-3

PMCID:: PMC8748677

Article PDF–4.0M

Select item 854821216.

A brain-specific pgc1α fusion transcript affects gene expression and behavioural outcomes in mice

Oswaldo A Lozoya, Fuhua Xu, Dagoberto Grenet, Tianyuan Wang, Korey D Stevanovic, Jesse D Cushman, Thomas B Hagler, Artiom Gruzdev, Patricia Jensen, Bairon Hernandez, Gonzalo Riadi, Sheryl S Moy, Janine H Santos, Richard P Woychik

Life Sci Alliance. 2021 Dec; 4(12): e202101122. Published online 2021 Oct 14. doi: 10.26508/lsa.202101122

Correction in:: Life Sci Alliance. 2022 Feb; 5(2): e202101295.

PMCID:: PMC8548212

Article PDF–2.0M

Select item 840065917.

Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-Induced Weight Gain in Male Mice

E. Matthew Morris, Roberto D. Noland, Michael E. Ponte, Michelle L. Montonye, Julie A. Christianson, John A. Stanford, John M. Miles, Matthew R. Hayes, John P. Thyfault

Nutrients. 2021 Aug; 13(8): 2596. Published online 2021 Jul 28. doi: 10.3390/nu13082596

PMCID:: PMC8400659

Article PDF–5.3M

Select item 815872418.

Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers

Philipp Kasper, Saida Breuer, Thorben Hoffmann, Christina Vohlen, Ruth Janoschek, Lisa Schmitz, Sarah Appel, Gregor Fink, Christoph Hünseler, Alexander Quaas, Münevver Demir, Sonja Lang, Hans-Michael Steffen, Anna Martin, Christoph Schramm, Martin Bürger, Esther Mahabir, Tobias Goeser, Jörg Dötsch, Eva Hucklenbruch-Rother, Inga Bae-Gartz

Cells. 2021 May; 10(5): 1247. Published online 2021 May 19. doi: 10.3390/cells10051247

PMCID:: PMC8158724

Article PDF–2.8M

Select item 805007019.

Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise

Jin Wang, Jing Tang, Xin Liang, Yanmin Luo, Peilin Zhu, Yue Li, Kai Xiao, Lin Jiang, Hao Yang, Yuhan Xie, Lei Zhang, Yuhui Deng, Jing Li, Yong Tang

Transl Psychiatry. 2021; 11: 222. Published online 2021 Apr 15. doi: 10.1038/s41398-021-01339-1

PMCID:: PMC8050070

Article PDF–1.3M

Select item 799399420.

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

Sina C Rosenkranz, Artem A Shaposhnykov, Simone Träger, Jan Broder Engler, Maarten E Witte, Vanessa Roth, Vanessa Vieira, Nanne Paauw, Simone Bauer, Celina Schwencke-Westphal, Charlotte Schubert, Lukas Can Bal, Benjamin Schattling, Ole Pless, Jack van Horssen, Marc Freichel, Manuel A Friese

eLife. 2021; 10: e61798. Published online 2021 Feb 10. doi: 10.7554/eLife.61798

PMCID:: PMC7993994

Article PDF–1.7M

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