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Select item 93053531.

Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina

Casey N. Barber, Hana L. Goldschmidt, Brendan Lilley, Alexei M. Bygrave, Richard C. Johnson, Richard L. Huganir, Donald J. Zack, Daniel M. Raben

J Lipid Res. 2022 Aug; 63(8): 100247. Published online 2022 Jun 25. doi: 10.1016/j.jlr.2022.100247

PMCID:: PMC9305353

Article PDF–5.8M

Select item 67781932.

VU0155069 inhibits inflammasome activation independent of phospholipase D1 activity

Sung Kyun Lee, Ye Seon Kim, Geon Ho Bae, Ha Young Lee, Yoe-Sik Bae

Sci Rep. 2019; 9: 14349. Published online 2019 Oct 4. doi: 10.1038/s41598-019-50806-9

PMCID:: PMC6778193

Article PDF–2.6M

Select item 60301883.

Phospholipase D1 regulation of TNF-alpha protects against responses to LPS

Marc-Andre Urbahn, Sonja Charlotte Kaup, Friedrich Reusswig, Irena Krüger, Martina Spelleken, Kerstin Jurk, Meike Klier, Philipp A. Lang, Margitta Elvers

Sci Rep. 2018; 8: 10006. Published online 2018 Jul 3. doi: 10.1038/s41598-018-28331-y

PMCID:: PMC6030188

Article PDF–10M

Select item 51569434.

Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect

Jang Ho Hur, Shi-Young Park, Claudia Dall’Armi, Jae Sung Lee, Gilbert Di Paolo, Hui-Young Lee, Mee-Sup Yoon, Do Sik Min, Cheol Soo Choi

Sci Rep. 2016; 6: 39170. Published online 2016 Dec 15. doi: 10.1038/srep39170

PMCID:: PMC5156943

Article PDF–2.6M

Select item 37014585.

Impaired α_IIbβ₃ integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1

Margitta Elvers, David Stegner, Ina Hagedorn, Christoph Kleinschnitz, Attila Braun, Marijke E.J. Kuijpers, Michael Boesl, Qin Chen, Johan W. M. Heemskerk, Guido Stoll, Michael A. Frohman, Bernhard Nieswandt

Sci Signal. Author manuscript; available in PMC 2013 Jul 4.

Published in final edited form as: Sci Signal. 2010 Jan 5; 3(103): ra1. Published online 2010 Jan 5. doi: 10.1126/scisignal.2000551

PMCID:: PMC3701458

Article PDF–2.0M

Select item 33283546.

The Phospholipase D1 Pathway Modulates Macroautophagy

Claudia Dall’Armi, Andres Hurtado-Lorenzo, Huasong Tian, Etienne Morel, Akiko Nezu, Robin B. Chan, W. Haung Yu, Kimberly S. Robinson, Oladapo Yeku, Scott A. Small, Karen Duff, Michael A. Frohman, Markus R. Wenk, Akitsugu Yamamoto, Gilbert Di Paolo

Nat Commun. Author manuscript; available in PMC 2012 Apr 17.

Published in final edited form as: Nat Commun. 2010; 1: 142. doi: 10.1038/ncomms1144

PMCID:: PMC3328354

Article PDF–6.6M

Select item 28925997.

Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic β cells

Wei-na Ma, Shin-Young Park, Joong-Soo Han

Exp Mol Med. 2010 Jun 30; 42(6): 456–464. Published online 2010 May 6. doi: 10.3858/emm.2010.42.6.047

PMCID:: PMC2892599

Article PDF–663K

Select item 28647668.

Phospholipase D1 Mediates TNFα-Induced Inflammation in a Murine Model of TNFα-Induced Peritonitis

Swaminathan Sethu, Peter N. Pushparaj, Alirio J. Melendez

PLoS One. 2010; 5(5): e10506. Published online 2010 May 5. doi: 10.1371/journal.pone.0010506

PMCID:: PMC2864766

Article PDF–1.3M

Select item 12207719.

Phospholipase D: molecular and cell biology of a novel gene family.

M Liscovitch, M Czarny, G Fiucci, X Tang

Biochem J. 2000 Feb 1; 345(Pt 3): 401–415.

PMCID:: PMC1220771

Summary PDF–211K

Select item 804893210.

PLD1 and PLD2 differentially regulate the balance of macrophage polarization in inflammation and tissue injury

Won Chan Hwang, Seol Hwa Seo, Minju Kang, Rae Hee Kang, Gilbert Di Paolo, Kang‐Yell Choi, Do Sik Min

J Cell Physiol. 2021 Jul; 236(7): 5193–5211. Published online 2020 Dec 23. doi: 10.1002/jcp.30224

PMCID:: PMC8048932

Article PDF–6.9M

Select item 769320811.

Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity

Dong Woo Kang, Won Chan Hwang, Yu Na Noh, Kang Seo Park, Do Sik Min

J Pathol. 2020 Nov; 252(3): 304–316. Published online 2020 Sep 10. doi: 10.1002/path.5519

PMCID:: PMC7693208

Article PDF–7.1M

Select item 755562412.

Phospholipase D1 and D2 Synergistically Regulate Thrombus Formation

Li-Ming Lien, Wan-Jung Lu, Ting-Yu Chen, Tzu-Yin Lee, Hsueh-Hsiao Wang, Hsien-Yu Peng, Ray-Jade Chen, Kuan-Hung Lin

Int J Mol Sci. 2020 Sep; 21(18): 6954. Published online 2020 Sep 22. doi: 10.3390/ijms21186954

PMCID:: PMC7555624

Article PDF–2.7M

Select item 693675213.

Biased M₁ receptor–positive allosteric modulators reveal role of phospholipase D in M₁-dependent rodent cortical plasticity

Sean P. Moran, Zixiu Xiang, Catherine A. Doyle, James Maksymetz, Xiaohui Lv, Sehr Faltin, Nicole M. Fisher, Colleen M. Niswender, Jerri M. Rook, Craig W. Lindsley, P. Jeffrey Conn

Sci Signal. Author manuscript; available in PMC 2020 Dec 3.

Published in final edited form as: Sci Signal. 2019 Dec 3; 12(610): eaax2057. Published online 2019 Dec 3. doi: 10.1126/scisignal.aax2057

PMCID:: PMC6936752

Article PDF–1.9M

Select item 689288914.

Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience

Krystyn Z. Bourne, Chandramouli Natarajan, Carlos X. Medina Perez, Batbayar Tumurbaatar, Giulio Taglialatela, Balaji Krishnan

Sci Rep. 2019; 9: 18342. Published online 2019 Dec 4. doi: 10.1038/s41598-019-54974-6

PMCID:: PMC6892889

Article PDF–2.2M

Select item 673437915.

Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis

Vidyani Suryadevara, Longshuang Huang, Seok-Jo Kim, Paul Cheresh, Mark Shaaya, Mounica Bandela, Panfeng Fu, Carol Feghali-Bostwick, Gilbert Di Paolo, David W. Kamp, Viswanathan Natarajan

Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1; 317(2): L175–L187. Published online 2019 May 15. doi: 10.1152/ajplung.00320.2018

PMCID:: PMC6734379

Article

Select item 672593816.

Phospholipase D1-Promoted Release of Tissue Plasminogen Activator Facilitates Neurite Outgrowth

Yan Zhang, Yasunori Kanaho, Michael A. Frohman, Stella E. Tsirka

J Neurosci. 2005 Feb 16; 25(7): 1797–1805. doi: 10.1523/JNEUROSCI.4850-04.2005

PMCID:: PMC6725938

Article PDF–590K

Select item 661876017.

The Coffin-Lowry Syndrome-Associated Protein RSK2 Regulates Neurite Outgrowth through Phosphorylation of Phospholipase D1 (PLD1) and Synthesis of Phosphatidic Acid

Mohamed-Raafet Ammar, Yann Humeau, André Hanauer, Bernard Nieswandt, Marie-France Bader, Nicolas Vitale

J Neurosci. 2013 Dec 11; 33(50): 19470–19479. doi: 10.1523/JNEUROSCI.2283-13.2013

PMCID:: PMC6618760

Article PDF–2.4M

Select item 637530518.

Phospholipase D isoforms differentially regulate leukocyte responses to acute lung injury

Raja-Elie E. Abdulnour, Judie A. Howrylak, Alexander H. Tavares, David N. Douda, Karen M. Henkels, Taylor E. Miller, Laura E. Fredenburgh, Rebecca M. Baron, Julian Gomez-Cambronero, Bruce D. Levy

J Leukoc Biol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: J Leukoc Biol. 2018 May; 103(5): 919–932. Published online 2018 Feb 13. doi: 10.1002/JLB.3A0617-252RR