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Items: 1 to 20 of 122

1.
Skewing cPLA2 activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis
Kenneth D. Maus, Daniel J. Stephenson, H. Patrick Macknight, Ngoc T. Vu, L. Alexis Hoeferlin, Minjung Kim, Robert F. Diegelmann, Xiujie Xie, Charles E. Chalfant
Sci Signal. Author manuscript; available in PMC 2023 Oct 11.
Published in final edited form as: Sci Signal. 2023 Jul 11; 16(793): eadd6527. Published online 2023 Jul 11. doi: 10.1126/scisignal.add6527
PMCID:
PMC10565596
ArticlePDF–2.9M
2.
Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice
Xiangli Zhao, Ronghan Liu, Yuehong Chen, Aubryanna Hettinghouse, Chuanju Liu
Int J Mol Sci. 2021 Oct; 22(20): 11155. Published online 2021 Oct 15. doi: 10.3390/ijms222011155
PMCID:
PMC8539349
ArticlePDF–5.6M
3.
A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A2
Priscila Motta Janovits, Elbio Leiguez, Viviane Portas, Catarina Teixeira
Biomolecules. 2021 Jul; 11(7): 921. Published online 2021 Jun 22. doi: 10.3390/biom11070921
PMCID:
PMC8301905
ArticlePDF–2.7M
4.
The effects of myelin on macrophage activation are phenotypic specific via cPLA2 in the context of spinal cord injury inflammation
Timothy J. Kopper, Bei Zhang, William M. Bailey, Kara E. Bethel, John C. Gensel
Sci Rep. 2021; 11: 6341. Published online 2021 Mar 18. doi: 10.1038/s41598-021-85863-6
PMCID:
PMC7973514
ArticlePDF–3.1M
5.
cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury
Yun Li, Jace W. Jones, Harry M. C. Choi, Chinmoy Sarkar, Maureen A. Kane, Eugene Y. Koh, Marta M. Lipinski, Junfang Wu
Cell Death Dis. 2019 Jul; 10(7): 531. Published online 2019 Jul 11. doi: 10.1038/s41419-019-1764-1
PMCID:
PMC6624263
ArticlePDF–2.2M
6.
Long-Term Potentiation at Cerebellar Parallel Fiber–Purkinje Cell Synapses Requires Presynaptic and Postsynaptic Signaling Cascades
De-Juan Wang, Li-Da Su, Ya-Nan Wang, Dong Yang, Cheng-Long Sun, Lin Zhou, Xin-Xin Wang, Ying Shen
J Neurosci. 2014 Feb 5; 34(6): 2355–2364. doi: 10.1523/JNEUROSCI.4064-13.2014
PMCID:
PMC6608543
ArticlePDF–3.9M
7.
cPLA2α-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+ current inhibition by M1 muscarinic receptor signaling
Liwang Liu, Joseph V. Bonventre, Ann R. Rittenhouse
PLoS One. 2018; 13(12): e0201322. Published online 2018 Dec 17. doi: 10.1371/journal.pone.0201322
PMCID:
PMC6296557
ArticlePDF–2.4M
8.
Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy
Ralf G. Rempe, Anika M.S. Hartz, Emma L.B. Soldner, Brent S. Sokola, Satya R. Alluri, Erin L. Abner, Richard J. Kryscio, Anton Pekcec, Juli Schlichtiger, Björn Bauer
J Neurosci. 2018 May 2; 38(18): 4301–4315. doi: 10.1523/JNEUROSCI.2751-17.2018
PMCID:
PMC5932641
ArticlePDF–2.6M
9.
Roles of cytosolic phospholipase A2α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed mice
Nozomi Fujisawa, Wataru Yoshioka, Hiroyuki Yanagisawa, Chiharu Tohyama
Arch Toxicol. 2018; 92(2): 789–801. Published online 2017 Oct 17. doi: 10.1007/s00204-017-2081-z
PMCID:
PMC5818604
ArticlePDF–1.2M
10.
Bone marrow-derived cPLA2α contributes to renal fibrosis progression
John R. Montford, Allison M. B. Lehman, Colin D. Bauer, Jelena Klawitter, Jost Klawitter, Joanna M. Poczobutt, Micah Scobey, Mary Weiser-Evans, Raphael A. Nemenoff, Seth B. Furgeson
J Lipid Res. 2018 Feb; 59(2): 380–390. Published online 2017 Dec 11. doi: 10.1194/jlr.M082362
PMCID:
PMC5794431
ArticlePDF–1.6M
11.
Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia
Yafa Fetfet Malada-Edelstein, Nurit Hadad, Rachel Levy
J Neuroinflammation. 2017; 14: 33. Published online 2017 Feb 10. doi: 10.1186/s12974-017-0811-z
PMCID:
PMC5303221
ArticlePDF–5.9M
12.
Off-target effect of the cPLA2α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum
Bogeon Yun, HeeJung Lee, Heather Ewing, Michael H. Gelb, Christina C. Leslie
Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Oct 7.
Published in final edited form as: Biochem Biophys Res Commun. 2016 Oct 7; 479(1): 61–66. Published online 2016 Sep 9. doi: 10.1016/j.bbrc.2016.09.033
PMCID:
PMC5063313
ArticlePDF–1.4M
13.
Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection
Sabarirajan Jayaraja, Azzeddine Dakhama, Bogeon Yun, Moumita Ghosh, HeeJung Lee, Elizabeth F. Redente, Charis L. Uhlson, Robert C. Murphy, Christina C. Leslie
BMC Immunol. 2016; 17: 27. Published online 2016 Aug 8. doi: 10.1186/s12865-016-0165-9
PMCID:
PMC4977843
ArticlePDF–1.5M
14.
Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis
Yulia Solomonov, Nurit Hadad, Rachel Levy
J Neuroinflammation. 2016; 13: 134. Published online 2016 Jun 1. doi: 10.1186/s12974-016-0602-y
PMCID:
PMC4888471
ArticlePDF–2.6M
15.
Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, Grace Y. Sun
J Neuroinflammation. 2015; 12: 199. Published online 2015 Oct 31. doi: 10.1186/s12974-015-0419-0
PMCID:
PMC4628268
ArticlePDF–2.4M
16.
Phospholipase A2 regulates eicosanoid class switching during inflammasome activation
Paul C. Norris, David Gosselin, Donna Reichart, Christopher K. Glass, Edward A. Dennis
Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): 12746–12751. Published online 2014 Aug 19. doi: 10.1073/pnas.1404372111
PMCID:
PMC4156727
ArticlePDF–1.1M
17.
Predominant Role of Cytosolic Phospholipase A2α in Dioxin-induced Neonatal Hydronephrosis in Mice
Wataru Yoshioka, Tatsuya Kawaguchi, Nozomi Fujisawa, Keiko Aida-Yasuoka, Takao Shimizu, Fumio Matsumura, Chiharu Tohyama
Sci Rep. 2014; 4: 4042. Published online 2014 Feb 10. doi: 10.1038/srep04042
PMCID:
PMC3918923
ArticlePDF–689K
18.
Genetic modulation of islet β-cell iPLA2β expression provides evidence for its impact on β-cell apoptosis and autophagy
Xiaoyong Lei, Robert N. Bone, Tomader Ali, Mary Wohltmann, Ying Gai, Karen J. Goodwin, Alan E. Bohrer, John Turk, Sasanka Ramanadham
Islets. 2013 Jan 1; 5(1): 29–44. Published online 2013 Jan 1. doi: 10.4161/isl.23758
PMCID:
PMC3662380
ArticlePDF–6.1M
19.
Cytosolic Phospholipase A2 alpha/Arachidonic Acid Signaling Mediates Depolarization-Induced Suppression of Excitation in the Cerebellum
De-Juan Wang, Dong Yang, Li-Da Su, Ya-jun Xie, Lin Zhou, Cheng-Long Sun, Yin Wang, Xin-Xin Wang, Liang Zhou, Ying Shen
PLoS One. 2012; 7(8): e41499. Published online 2012 Aug 22. doi: 10.1371/journal.pone.0041499
Correction in:
PLoS One. 2012; 7(11): 10.1371/annotation/d08032c8-4a27-4c9c-8ef7-b3ec64351cde.
PMCID:
PMC3425552
ArticlePDF–726K
20.
Phospholipase A2IVα Regulates Phagocytosis Independent of Its Enzymatic Activity
Pasquale Zizza, Cristiano Iurisci, Matteo Bonazzi, Pascale Cossart, Christina C. Leslie, Daniela Corda, Stefania Mariggiò
J Biol Chem. 2012 May 11; 287(20): 16849–16859. Published online 2012 Mar 5. doi: 10.1074/jbc.M111.309419
PMCID:
PMC3351341
ArticlePDF–1.2M

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