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1.
Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms
Kazuma Kaneko, Kohjiro Ueki, Noriko Takahashi, Shinji Hashimoto, Masayuki Okamoto, Motoharu Awazawa, Yukiko Okazaki, Mitsuru Ohsugi, Kazunori Inabe, Toshihiro Umehara, Masashi Yoshida, Masafumi Kakei, Tadahiro Kitamura, Ji Luo, Rohit N. Kulkarni, C. Ronald Kahn, Haruo Kasai, Lewis C. Cantley, Takashi Kadowaki
Cell Metab. Author manuscript; available in PMC 2013 Aug 7.
Published in final edited form as: Cell Metab. 2010 Dec 1; 12(6): 619–632. doi: 10.1016/j.cmet.2010.11.005
PMCID:
PMC3736578
ArticlePDF–2.4M
2.
Acute Inhibition of PI3K-PDK1-Akt Pathway Potentiates Insulin Secretion through Upregulation of Newcomer Granule Fusions in Pancreatic β-Cells
Kyota Aoyagi, Mica Ohara-Imaizumi, Chiyono Nishiwaki, Yoko Nakamichi, Kohjiro Ueki, Takashi Kadowaki, Shinya Nagamatsu
PLoS One. 2012; 7(10): e47381. Published online 2012 Oct 15. doi: 10.1371/journal.pone.0047381
PMCID:
PMC3471824
ArticlePDF–990K
3.
Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo
Laura S. Haneline, Hilary White, Feng-Chun Yang, Shi Chen, Christie Orschell, Reuben Kapur, David A. Ingram
Blood. 2006 Feb 15; 107(4): 1375–1382. Prepublished online 2005 Oct 20. doi: 10.1182/blood-2005-05-1985
PMCID:
PMC1895408
Article
4.
T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling
Jonathan A. Deane, Michael G. Kharas, Jean S. Oak, Linda N. Stiles, Ji Luo, Travis I. Moore, Hong Ji, Christian Rommel, Lewis C. Cantley, Thomas E. Lane, David A. Fruman
Blood. 2007 Apr 1; 109(7): 2894–2902. Prepublished online 2006 Dec 12. doi: 10.1182/blood-2006-07-038620
PMCID:
PMC1852227
Article
5.
Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase
Jean S. Oak, Jonathan A. Deane, Michael G. Kharas, Ji Luo, Thomas E. Lane, Lewis C. Cantley, David A. Fruman
Proc Natl Acad Sci U S A. 2006 Nov 7; 103(45): 16882–16887. Published online 2006 Oct 27. doi: 10.1073/pnas.0607984103
Correction in:
Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26): 10871.
PMCID:
PMC1636548
ArticlePDF–777K
6.
Class IA Phosphoinositide 3-Kinase Regulates Heart Size and Physiological Cardiac Hypertrophy
Ji Luo, Julie R. McMullen, Cassandra L. Sobkiw, Li Zhang, Adam L. Dorfman, Megan C. Sherwood, M. Nicole Logsdon, James W. Horner, Ronald A. DePinho, Seigo Izumo, Lewis C. Cantley
Mol Cell Biol. 2005 Nov; 25(21): 9491–9502. doi: 10.1128/MCB.25.21.9491-9502.2005
PMCID:
PMC1265829
ArticlePDF–798K
7.
Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement
Saskia M. Brachmann, Claudine M. Yballe, Metello Innocenti, Jonathan A. Deane, David A. Fruman, Sheila M. Thomas, Lewis C. Cantley
Mol Cell Biol. 2005 Apr; 25(7): 2593–2606. doi: 10.1128/MCB.25.7.2593-2606.2005
PMCID:
PMC1061637
ArticlePDF–911K
8.
Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase
Kohjiro Ueki, Claudine M. Yballe, Saskia M. Brachmann, David Vicent, John M. Watt, C. Ronald Kahn, Lewis C. Cantley
Proc Natl Acad Sci U S A. 2002 Jan 8; 99(1): 419–424. Published online 2001 Dec 18. doi: 10.1073/pnas.012581799
PMCID:
PMC117575
ArticlePDF–226K
9.
Optogenetic Control of PIP3: PIP3 Is Sufficient to Induce the Actin-Based Active Part of Growth Cones and Is Regulated via Endocytosis
Toshiyuki Kakumoto, Takao Nakata
PLoS One. 2013; 8(8): e70861. Published online 2013 Aug 7. doi: 10.1371/journal.pone.0070861
PMCID:
PMC3737352
ArticlePDF–9.8M
10.
p85β phosphoinositide 3-kinase subunit regulates tumor progression
Isabel Cortés, Jesús Sánchez-Ruíz, Susana Zuluaga, Vincenzo Calvanese, Miriam Marqués, Carmen Hernández, Teresa Rivera, Leonor Kremer, Ana González-García, Ana C. Carrera
Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11318–11323. Published online 2012 Jun 25. doi: 10.1073/pnas.1118138109
PMCID:
PMC3396516
ArticlePDF–1.3M
11.
PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation
Ekaterina Bobrovnikova-Marjon, Dariusz Pytel, Matthew J. Riese, Laura Pontano Vaites, Nickpreet Singh, Gary A. Koretzky, Eric S. Witze, J. Alan Diehl
Mol Cell Biol. 2012 Jun; 32(12): 2268–2278. doi: 10.1128/MCB.00063-12
PMCID:
PMC3372262
ArticlePDF–2.0M
12.
The p85β regulatory subunit of phosphoinositide 3-kinase has unique and redundant functions in B cells
JEAN S. OAK, JING CHEN, RAECHEL Q. PERALTA, JONATHAN A. DEANE, DAVID A. FRUMAN
Autoimmunity. Author manuscript; available in PMC 2010 Jan 11.
Published in final edited form as: Autoimmunity. 2009 Aug; 42(5): 447–458. doi: 10.1080/08916930902911746
PMCID:
PMC2804088
ArticlePDF–1.5M
13.
Tim-1-Mediated T Cell Activation Requires Recruitment and Activation of PI 3-Kinase
Anjali J. de Souza, Jean S. Oak, Ryan Jordanhazy, Rosemarie H. DeKruyff, David A. Fruman, Lawrence P. Kane
J Immunol. Author manuscript; available in PMC 2009 May 15.
Published in final edited form as: J Immunol. 2008 May 15; 180(10): 6518–6526. doi: 10.4049/jimmunol.180.10.6518
PMCID:
PMC2637999
ArticlePDF–1.2M
14.
Class 1A PI3K regulates vessel integrity during development and tumorigenesis
Tina L. Yuan, Hak Soo Choi, Aya Matsui, Cyril Benes, Eugene Lifshits, Ji Luo, John V. Frangioni, Lewis C. Cantley
Proc Natl Acad Sci U S A. 2008 Jul 15; 105(28): 9739–9744. Published online 2008 Jul 10. doi: 10.1073/pnas.0804123105
PMCID:
PMC2453070
ArticlePDF–1.0M
15.
Phosphoinositide 3-Kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane
Alexander T. Stein, Carmen A. Ufret-Vincenty, Li Hua, Luis F. Santana, Sharona E. Gordon
J Gen Physiol. 2006 Nov; 128(5): 509–522. doi: 10.1085/jgp.200609576
PMCID:
PMC2151588
ArticlePDF–2.9M
16.
Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase
Ji Luo, Cassandra L. Sobkiw, Nicole M. Logsdon, John M. Watt, Sabina Signoretti, Fionnuala O'Connell, Eyoung Shin, Youngju Shim, Lily Pao, Benjamin G. Neel, Ronald A. DePinho, Massimo Loda, Lewis C. Cantley
Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29): 10238–10243. Published online 2005 Jul 8. doi: 10.1073/pnas.0504378102
PMCID:
PMC1174923
ArticlePDF–735K
17.
p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis
Subha Krishnan, Raghuveer Singh Mali, Baskar Ramdas, Emily Sims, Peilin Ma, Joydeep Ghosh, Veerendra Munugalavadla, Philip Hanneman, Joal D. Beane, Reuben Kapur
Blood. 2012 Apr 26; 119(17): 3951–3961. Prepublished online 2012 Feb 29. doi: 10.1182/blood-2011-05-355602
PMCID:
PMC3350362
Article
18.
Nuclear but Not Cytosolic Phosphoinositide 3-Kinase Beta Has an Essential Function in Cell Survival
Amit Kumar, Javier Redondo-Muñoz, Vicente Perez-García, Isabel Cortes, Monica Chagoyen, Ana C. Carrera
Mol Cell Biol. 2011 May; 31(10): 2122–2133. doi: 10.1128/MCB.01313-10
PMCID:
PMC3133359
ArticlePDF–2.7M
19.
Dual Regulatory Roles of the Phosphatidylinositol 3-Kinase In Interferon Signaling
Surinder Kaur, Antonella Sassano, Ajith M Joseph, Beata Majchrzak-Kita, Elizabeth A. Eklund, Amit Verma, Saskia M. Brachmann, Eleanor N. Fish, Leonidas C. Platanias
J Immunol. Author manuscript; available in PMC 2009 Nov 15.
Published in final edited form as: J Immunol. 2008 Nov 15; 181(10): 7316–7323. doi: 10.4049/jimmunol.181.10.7316
PMCID:
PMC2597572
ArticlePDF–1012K
20.
The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation
M. A. Bender, Tobias Ragoczy, Jongjoo Lee, Rachel Byron, Agnes Telling, Ann Dean, Mark Groudine
Blood. 2012 Apr 19; 119(16): 3820–3827. Prepublished online 2012 Feb 29. doi: 10.1182/blood-2011-09-380485
PMCID:
PMC3335386
Article

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