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Select item 105566331.

Circadian ribosome profiling reveals a role for the Period2 upstream open reading frame in sleep

Arthur Millius, Rikuhiro G. Yamada, Hiroshi Fujishima, Kazuhiko Maeda, Daron M. Standley, Kenta Sumiyama, Dimitri Perrin, Hiroki R. Ueda

Proc Natl Acad Sci U S A. 2023 Oct 3; 120(40): e2214636120. Published online 2023 Sep 28. doi: 10.1073/pnas.2214636120

PMCID:: PMC10556633

Article PDF–1.2M

Select item 104456522.

Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light–dark cycles in mice

Ruoshi Li, Kosaku Masuda, Daisuke Ono, Takashi Kanbayashi, Arisa Hirano, Takeshi Sakurai

Front Neurosci. 2023; 17: 1201137. Published online 2023 Aug 9. doi: 10.3389/fnins.2023.1201137

PMCID:: PMC10445652

Article PDF–6.0M

Select item 101236563.

Deletion of the Circadian Clock Gene Per2 in the Whole Body, but Not in Neurons or Astroglia, Affects Sleep in Response to Sleep Deprivation

Katrin S. Wendrich, Hamid Azimi, Jürgen A. Ripperger, Yann Ravussin, Gregor Rainer, Urs Albrecht

Clocks Sleep. 2023 Jun; 5(2): 204–225. Published online 2023 Apr 13. doi: 10.3390/clockssleep5020017

PMCID:: PMC10123656

Article PDF–2.9M

Select item 97087914.

PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop

Aris T. Alexandrou, Yixin Duan, Shanxiu Xu, Clifford Tepper, Ming Fan, Jason Tang, Jonathan Berg, Wassim Basheer, Tyler Valicenti, Paul F. Wilson, Matthew A. Coleman, Andrew T. Vaughan, Loning Fu, David J. Grdina, Jefferey Murley, Aijun Wang, Gayle Woloschak, Jian Jian Li

iScience. 2022 Dec 22; 25(12): 105546. Published online 2022 Nov 9. doi: 10.1016/j.isci.2022.105546

PMCID:: PMC9708791

Article PDF–6.4M

Select item 95883835.

Attenuation by Time-Restricted Feeding of High-Fat and High-Fructose Diet-Induced NASH in Mice Is Related to Per2 and Ferroptosis

Yan-yun Shu, Wen-kang Gao, Hui-kuan Chu, Ling Yang, Xiao-li Pan, Jin Ye

Oxid Med Cell Longev. 2022; 2022: 8063897. Published online 2022 Oct 15. doi: 10.1155/2022/8063897

PMCID:: PMC9588383

Article PDF–4.5M

Select item 93256076.

Impacts of Circadian Gene Period2 Knockout on Intestinal Metabolism and Hepatic Antioxidant and Inflammation State in Mice

Yongkang Zhen, Zanna Xi, Liangyu Hu, Yifei Chen, Ling Ge, Wenjun Wei, Juan J. Loor, Qingyong Yang, Mengzhi Wang

Oxid Med Cell Longev. 2022; 2022: 7896371. Published online 2022 Jul 19. doi: 10.1155/2022/7896371

PMCID:: PMC9325607

Article PDF–2.8M

Select item 90377067.

Intense light-elicited alveolar type 2-specific circadian PER2 protects from bacterial lung injury via BPIFB1

Yoshimasa Oyama, Sydney R. Shuff, Nana Burns, Christine U. Vohwinkel, Tobias Eckle

Am J Physiol Lung Cell Mol Physiol. 2022 May 1; 322(5): L647–L661. Published online 2022 Mar 10. doi: 10.1152/ajplung.00301.2021

PMCID:: PMC9037706

Article

Select item 87980538.

The sleep-wake distribution contributes to the peripheral rhythms in PERIOD-2

Marieke MB Hoekstra, Maxime Jan, Georgia Katsioudi, Yann Emmenegger, Paul Franken

eLife. 2021; 10: e69773. Published online 2021 Dec 13. doi: 10.7554/eLife.69773

PMCID:: PMC8798053

Article PDF–3.1M

Select item 87955369.

Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons

Nicola J. Smyllie, James Bagnall, Alex A. Koch, Dhevahi Niranjan, Lenka Polidarova, Johanna E. Chesham, Jason W. Chin, Carrie L. Partch, Andrew S. I. Loudon, Michael H. Hastings

Proc Natl Acad Sci U S A. 2022 Jan 25; 119(4): e2113845119. Published online 2022 Jan 19. doi: 10.1073/pnas.2113845119

PMCID:: PMC8795536

Article PDF–2.0M

Select item 872243010.

Photoreceptor degeneration in homozygous male Per2^luc mice during aging

Varunika Goyal, Christopher DeVera, Kenkichi Baba, Jana Sellers, Micah A. Chrenek, P. Michael Iuvone, Gianluca Tosini

J Biol Rhythms. Author manuscript; available in PMC 2022 Jan 3.

Published in final edited form as: J Biol Rhythms. 2021 Apr; 36(2): 137–145. Published online 2020 Nov 2. doi: 10.1177/0748730420965285

PMCID:: PMC8722430

Article PDF–641K

Select item 865084011.

Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver

MengLin Chen, Min Chen, Danyi Lu, Yi Wang, Li Zhang, Zhigang Wang, Baojian Wu

Front Pharmacol. 2021; 12: 764124. Published online 2021 Nov 23. doi: 10.3389/fphar.2021.764124

PMCID:: PMC8650840

Article PDF–2.4M

Select item 819252112.

Deletion of the clock gene Period2 (Per2) in glial cells alters mood-related behavior in mice

Tomaz Martini, Jürgen A. Ripperger, Jimmy Stalin, Andrej Kores, Michael Stumpe, Urs Albrecht

Sci Rep. 2021; 11: 12242. Published online 2021 Jun 10. doi: 10.1038/s41598-021-91770-7

PMCID:: PMC8192521

Article PDF–9.2M

Select item 819189513.

Targeted modification of the Per2 clock gene alters circadian function in mPer2^luciferase (mPer2^Luc) mice

Martin R. Ralph, Shu-qun Shi, Carl H. Johnson, Pavel Houdek, Tenjin C. Shrestha, Priya Crosby, John S. O’Neill, Martin Sládek, Adam R. Stinchcombe, Alena Sumová

PLoS Comput Biol. 2021 May; 17(5): e1008987. Published online 2021 May 28. doi: 10.1371/journal.pcbi.1008987

PMCID:: PMC8191895

Article PDF–6.2M

Select item 813455414.

PER2-mediated ameloblast differentiation via PPARγ/AKT1/β-catenin axis

Wushuang Huang, Xueqing Zheng, Mei Yang, Ruiqi Li, Yaling Song

Int J Oral Sci. 2021; 13: 16. Published online 2021 May 19. doi: 10.1038/s41368-021-00123-7

PMCID:: PMC8134554

Article PDF–4.5M

Select item 768974315.

Period2 gene regulates diurnal changes of nasal symptoms in an allergic rhinitis mouse model

Feng‐Li Cheng, Yun‐Fang An, Zhuo‐Qin Han, Chao Li, Ze‐Qing Li, Ping‐Chang Yang, Chang‐Qing Zhao

Int Forum Allergy Rhinol. 2020 Nov; 10(11): 1236–1248. Published online 2020 Jul 1. doi: 10.1002/alr.22607

PMCID:: PMC7689743

Article PDF–1.8M

Select item 742799016.

Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape

Hee Kee Kim, Sun-Yeul Lee, Nobuya Koike, Eunju Kim, Marvin Wirianto, Mark J. Burish, Kazuhiro Yagita, Hyun Kyoung Lee, Zheng Chen, Jin Mo Chung, Salahadin Abdi, Seung-Hee Yoo

Sci Rep. 2020; 10: 13844. Published online 2020 Aug 14. doi: 10.1038/s41598-020-70757-w