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Items: 1 to 20 of 402

1.
OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1
Ramkumar Mohan, Seokwon Jo, Amber Lockridge, Deborah A. Ferrington, Kevin Murray, Arthur Eschenlauer, Ernesto Bernal-Mizrachi, Yoshio Fujitani, Emilyn U. Alejandro
Diabetes. 2021 Nov; 70(11): 2608–2625. Published online 2021 Aug 30. doi: 10.2337/db21-0468
PMCID:
PMC8564412
ArticlePDF–3.7M
2.
Acarbose ameliorates spontaneous type-2 diabetes in db/db mice by inhibiting PDX-1 methylation
Diyi Zhou, Lijun Chen, Xin Mou
Mol Med Rep. 2021 Jan; 23(1): 72. Published online 2020 Nov 20. doi: 10.3892/mmr.2020.11710
PMCID:
PMC7716388
ArticlePDF–869K
3.
Neonatal diabetes mellitus with pancreatic agenesis in an infant with homozygous IPF-1 Pro63fsX60 mutation
Inas H. Thomas, Natinder K. Saini, Amita Adhikari, Joyce M. Lee, Josephine Z. Kasa-vubu, Delia M. Vazquez, Ram K. Menon, Ming Chen, Stefan S. Fajans
Pediatr Diabetes. Author manuscript; available in PMC 2020 Jan 9.
Published in final edited form as: Pediatr Diabetes. 2009 Nov; 10(7): 492–496. Published online 2009 Jun 3. doi: 10.1111/j.1399-5448.2009.00526.x
PMCID:
PMC6951802
ArticlePDF–726K
4.
A PDX1-ATF transcriptional complex governs β cell survival during stress
Christine A. Juliana, Juxiang Yang, Corey E. Cannon, Austin L. Good, Matthew W. Haemmerle, Doris A. Stoffers
Mol Metab. 2018 Nov; 17: 39–48. Published online 2018 Aug 1. doi: 10.1016/j.molmet.2018.07.007
PMCID:
PMC6197747
ArticlePDF–1.5M
5.
Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model
Chuang Guo, Shuai Zhang, Jia-Yi Li, Chen Ding, Zhao-Hui Yang, Rui Chai, Xu Wang, Zhan-You Wang
Sci Rep. 2016; 6: 29396. Published online 2016 Jul 12. doi: 10.1038/srep29396
PMCID:
PMC4942607
ArticlePDF–2.6M
6.
Pdx1 maintains β-cell identity and function by repressing an α-cell program
Tao Gao, Brian McKenna, Changhong Li, Maximilian Reichert, James Nguyen, Tarjinder Singh, Chenghua Yang, Archana Pannikar, Nicolai Doliba, Tingting Zhang, Doris A. Stoffers, Helena Edlund, Franz Matschinsky, Roland Stein, Ben Z. Stanger
Cell Metab. Author manuscript; available in PMC 2015 Feb 4.
Published in final edited form as: Cell Metab. 2014 Feb 4; 19(2): 259–271. doi: 10.1016/j.cmet.2013.12.002
PMCID:
PMC3950964
ArticlePDF–3.3M
7.
Intestinal Pdx1 mediates nutrient metabolism gene networks and maternal expression is essential for perinatal growth in mice
Chin Chen, Tripp Leavitt, Eric Sibley
Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Aug 3.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Aug 3; 424(3): 549–553. Published online 2012 Jul 6. doi: 10.1016/j.bbrc.2012.06.153
PMCID:
PMC3412912
ArticlePDF–823K
8.
Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice
Chin Chen, Eric Sibley
Am J Physiol Gastrointest Liver Physiol. 2012 Feb; 302(4): G407–G419. Published online 2011 Dec 1. doi: 10.1152/ajpgi.00314.2011
PMCID:
PMC3287393
Article
9.
Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells
Chin Chen, Rixun Fang, Corrine Davis, Charalambos Maravelias, Eric Sibley
Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6): G1126–G1137. Published online 2009 Oct 1. doi: 10.1152/ajpgi.90586.2008
PMCID:
PMC2850094
Article
10.
Pancreatic Ductal Morphogenesis and the Pdx1 Homeodomain Transcription Factor
Melanie P. Wescott, Meritxell Rovira, Maximilian Reichert, Johannes von Burstin, Anna Means, Steven D. Leach, Anil K. Rustgi
Mol Biol Cell. 2009 Nov 15; 20(22): 4838–4844. doi: 10.1091/mbc.E09-03-0203
PMCID:
PMC2777112
ArticlePDF–1.8M
11.
Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress
Mira M. Sachdeva, Kathryn C. Claiborn, Cynthia Khoo, Juxiang Yang, David N. Groff, Raghavendra G. Mirmira, Doris A. Stoffers
Proc Natl Acad Sci U S A. 2009 Nov 10; 106(45): 19090–19095. Published online 2009 Oct 23. doi: 10.1073/pnas.0904849106
PMCID:
PMC2776433
ArticlePDF–1.9M
12.
Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome
James D. Johnson, Ernesto Bernal-Mizrachi, Emilyn U. Alejandro, Zhiqiang Han, Tatyana B. Kalynyak, Hong Li, Jennifer L. Beith, Julia Gross, Garth L. Warnock, R. Reid Townsend, M. Alan Permutt, Kenneth S. Polonsky
Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51): 19575–19580. Published online 2006 Dec 8. doi: 10.1073/pnas.0604208103
PMCID:
PMC1748267
ArticlePDF–1.7M
13.
Development of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1
Melissa K. Thomas, Octavia N. Devon, Jee H. Lee, Andreas Peter, David A. Schlosser, Matthew S. Tenser, Joel F. Habener
J Clin Invest. 2001 Jul 15; 108(2): 319–329. doi: 10.1172/JCI12029
PMCID:
PMC203024
ArticlePDF–704K
14.
Increased islet apoptosis in Pdx1+/– mice
James D. Johnson, Noreen T. Ahmed, Dan S. Luciani, Zhiqiang Han, Hung Tran, Jun Fujita, Stanley Misler, Helena Edlund, Kenneth S. Polonsky
J Clin Invest. 2003 Apr 15; 111(8): 1147–1160. doi: 10.1172/JCI16537
PMCID:
PMC152933
ArticlePDF–3.6M
15.
Experimental control of pancreatic development and maintenance
Andrew M. Holland, Michael A. Hale, Hideaki Kagami, Robert E. Hammer, Raymond J. MacDonald
Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19): 12236–12241. Published online 2002 Sep 9. doi: 10.1073/pnas.192255099
PMCID:
PMC129428
ArticlePDF–669K
16.
Functional Conservation of Regulatory Elements in the pdx-1 Gene: PDX-1 and Hepatocyte Nuclear Factor 3β Transcription Factors Mediate β-Cell-Specific Expression
Sonya Marshak, Etty Benshushan, Michal Shoshkes, Leora Havin, Erol Cerasi, Danielle Melloul
Mol Cell Biol. 2000 Oct; 20(20): 7583–7590. doi: 10.1128/mcb.20.20.7583-7590.2000
PMCID:
PMC86312
ArticlePDF–1.2M
17.
Intracellular ATP Signaling Contributes to FAM3A-Induced PDX1 Upregulation in Pancreatic Beta Cells
Han Yan, Zhenzhen Chen, Haizeng Zhang, Weili Yang, Xiangyang Liu, Yuhong Meng, Rui Xiang, Zhe Wu, Jingjing Ye, Yujing Chi, Jichun Yang
Exp Clin Endocrinol Diabetes. 2022 Aug; 130(8): 498–508. Published online 2021 Sep 30. doi: 10.1055/a-1608-0607
PMCID:
PMC9377833
ArticlePDF–1.4M
18.
Islet transplantation into brown adipose tissue can delay immune rejection
Jessica D. Kepple, Jessie M. Barra, Martin E. Young, Chad S. Hunter, Hubert M. Tse
JCI Insight. 2022 Feb 22; 7(4): e152800. Published online 2022 Feb 22. doi: 10.1172/jci.insight.152800
PMCID:
PMC8876467
ArticlePDF–14M
19.
Development of thymic tumor in [LSL:KrasG12D; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis
Sophie Liot, Naïma El Kholti, Jonathan Balas, Laurent Genestier, Bernard Verrier, Ulrich Valcourt, Elise Lambert
Sci Rep. 2021; 11: 15075. Published online 2021 Jul 23. doi: 10.1038/s41598-021-94566-x
PMCID:
PMC8302691
ArticlePDF–6.8M
20.
Flow cytometry detection of surface and intracellular antigens in pancreas from a single mouse embryo
Pia Nyeng, Gelo Victoriano Dela Cruz, Henrik Semb
STAR Protoc. 2021 Sep 17; 2(3): 100636. Published online 2021 Jun 30. doi: 10.1016/j.xpro.2021.100636
PMCID:
PMC8255939
ArticlePDF–5.6M

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