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Items: 1 to 20 of 63

1.
Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression
Anna Garrido-Utrilla, Chaïma Ayachi, Marika Elsa Friano, Josipa Atlija, Shruti Balaji, Tiziana Napolitano, Serena Silvano, Noémie Druelle, Patrick Collombat
Front Endocrinol (Lausanne) 2022; 13: 861922. Published online 2022 Apr 29. doi: 10.3389/fendo.2022.861922
PMCID:
PMC9103212
ArticlePDF–8.1M
2.
Ectopic expression of Pax4 in pancreatic δ cells results in β-like cell neogenesis
Noémie Druelle, Andhira Vieira, Aidin Shabro, Monica Courtney, Magali Mondin, Samah Rekima, Tiziana Napolitano, Serena Silvano, Sergi Navarro-Sanz, Biljana Hadzic, Fabio Avolio, Minoo Rassoulzadegan, Herbert A. Schmid, Ahmed Mansouri, Patrick Collombat
J Cell Biol. 2017 Dec 4; 216(12): 4299–4311. doi: 10.1083/jcb.201704044
PMCID:
PMC5716283
ArticlePDF–3.1M
3.
Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization
Alexandra Volodin, Idit Kosti, Alfred Lewis Goldberg, Shenhav Cohen
Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1375–E1384. Published online 2017 Jan 17. doi: 10.1073/pnas.1612988114
PMCID:
PMC5338431
ArticlePDF–1.3M
4.
PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus
José Manuel Mellado-Gil, Carmen María Jiménez-Moreno, Alejandro Martin-Montalvo, Ana Isabel Alvarez-Mercado, Esther Fuente-Martin, Nadia Cobo-Vuilleumier, Petra Isabel Lorenzo, Eva Bru-Tari, Irene de Gracia Herrera-Gómez, Livia López-Noriega, Javier Pérez-Florido, Javier Santoyo-López, Andreas Spyrantis, Paolo Meda, Bernhard O. Boehm, Ivan Quesada, Benoit R. Gauthier
Diabetologia. 2016; 59: 755–765. Published online 2016 Jan 26. doi: 10.1007/s00125-016-3864-0
PMCID:
PMC4779135
ArticlePDF–1.9M
5.
Enhancement of insulin-producing cell differentiation from embryonic stem cells using pax4-nucleofection method
Han-Tso Lin, Chung-Lan Kao, Kun-Hsiung Lee, Yuh-Lih Chang, Shih-Hwa Chiou, Fu-Ting Tsai, Tung-Hu Tsai, Dey-Chyi Sheu, Larry LT Ho, Hung-Hai Ku
World J Gastroenterol. 2007 Mar 21; 13(11): 1672–1679. Published online 2007 Mar 21. doi: 10.3748/wjg.v13.i11.1672
PMCID:
PMC4146945
ArticlePDF–1.4M
6.
Generation of animals allowing the conditional inactivation of the Pax4 gene
Simon Kordowich, Palle Serup, Patrick Collombat, Ahmed Mansouri
Transgenic Res. 2012; 21(6): 1215–1220. Published online 2012 Jun 21. doi: 10.1007/s11248-012-9624-0
PMCID:
PMC3505494
ArticlePDF–948K
7.
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into a- and subsequently ß-cells
Patrick Collombat, Xiaobo Xu, Philippe Ravassard, Beatriz Sosa-Pineda, Sébastien Dussaud, Nils Billestrup, Ole D. Madsen, Palle Serup, Harry Heimberg, Ahmed Mansouri
Cell. Author manuscript; available in PMC 2010 Aug 7.
Published in final edited form as: Cell. 2009 Aug 7; 138(3): 449–462. doi: 10.1016/j.cell.2009.05.035
PMCID:
PMC2792203
ArticlePDF–3.6M
8.
Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
Przemyslaw Blyszczuk, Jaroslaw Czyz, Gabriela Kania, Martin Wagner, Ursula Roll, Luc St-Onge, Anna M. Wobus
Proc Natl Acad Sci U S A. 2003 Feb 4; 100(3): 998–1003. Published online 2003 Jan 13. doi: 10.1073/pnas.0237371100
PMCID:
PMC298715
ArticlePDF–649K
9.
Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas
Yoshio Fujitani, Yoshitaka Kajimoto, Tetsuyuki Yasuda, Taka-Aki Matsuoka, Hideaki Kaneto, Yutaka Umayahara, Noriko Fujita, Hirotaka Watada, Jun-Ichi Miyazaki, Yoshimitsu Yamasaki, Masatsugu Hori
Mol Cell Biol. 1999 Dec; 19(12): 8281–8291. doi: 10.1128/mcb.19.12.8281
PMCID:
PMC84912
ArticlePDF–1024K
10.
PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet
Petra I. Lorenzo, Esther Fuente-Martín, Thierry Brun, Nadia Cobo-Vuilleumier, Carmen María Jimenez-Moreno, Irene G. Herrera Gomez, Livia López Noriega, José Manuel Mellado-Gil, Alejandro Martin-Montalvo, Bernat Soria, Benoit R. Gauthier
Sci Rep. 2015; 5: 15672. Published online 2015 Oct 27. doi: 10.1038/srep15672
PMCID:
PMC4622080
ArticlePDF–3.1M
11.
The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice
Anthony Beucher, Elisabet Gjernes, Caitlin Collin, Monica Courtney, Aline Meunier, Patrick Collombat, Gérard Gradwohl
PLoS One. 2012; 7(5): e36449. Published online 2012 May 3. doi: 10.1371/journal.pone.0036449
PMCID:
PMC3343025
ArticlePDF–3.6M
12.
In Vivo Conditional Pax4 Overexpression in Mature Islet β-Cells Prevents Stress-Induced Hyperglycemia in Mice
Kai Hui Hu He, Petra I. Lorenzo, Thierry Brun, Carmen M. Jimenez Moreno, Deborah Aeberhard, Jorge Vallejo Ortega, Marion Cornu, Fabrizio Thorel, Asllan Gjinovci, Bernard Thorens, Pedro L. Herrera, Paolo Meda, Claes B. Wollheim, Benoit R. Gauthier
Diabetes. 2011 Jun; 60(6): 1705–1715. Published online 2011 May 21. doi: 10.2337/db10-1102
PMCID:
PMC3114382
ArticlePDF–1.8M
13.
Developmental and daily expression of the Pax4 and Pax6 homeobox genes in the rat retina: localization of Pax4 in photoreceptor cells
Martin F. Rath, Michael J. Bailey, Jong-So Kim, Steven L. Coon, David C. Klein, Morten Møller
J Neurochem. Author manuscript; available in PMC 2019 May 21.
Published in final edited form as: J Neurochem. 2009 Jan; 108(1): 285–294. Published online 2008 Nov 19. doi: 10.1111/j.1471-4159.2008.05765.x
PMCID:
PMC6528810
ArticlePDF–1.7M
14.
Immunodeficient and immunosuppressed mice as models to test anti-Pneumocystis carinii drugs.
P D Walzer, J Runck, P Steele, M White, M J Linke, C L Sidman
Antimicrob Agents Chemother. 1997 Feb; 41(2): 251–258. doi: 10.1128/aac.41.2.251
PMCID:
PMC163697
SummaryPDF–1018K
15.
Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development
Stuart B. Smith, Hooi C. Ee, Jennifer R. Conners, Michael S. German
Mol Cell Biol. 1999 Dec; 19(12): 8272–8280. doi: 10.1128/mcb.19.12.8272
PMCID:
PMC84911
ArticlePDF–451K
16.
Intestinal Neurogenin 3 Directs Differentiation of a Bipotential Secretory Progenitor to Endocrine Cell Rather than Goblet Cell Fate
Lymari López-Díaz, Renu N. Jain, Theresa M. Keeley, Kelli L. VanDussen, Cynthia S. Brunkan, Deborah L. Gumucio, Linda C. Samuelson
Dev Biol. Author manuscript; available in PMC 2009 May 8.
Published in final edited form as: Dev Biol. 2007 Sep 15; 309(2): 298–305. Published online 2007 Jul 24. doi: 10.1016/j.ydbio.2007.07.015
PMCID:
PMC2679162
ArticlePDF–2.0M
17.
Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero
Hong-Ming Zhou, Simon J. Conway
J Dev Biol. 2022 Jun; 10(2): 19. Published online 2022 May 17. doi: 10.3390/jdb10020019
PMCID:
PMC9149870
ArticlePDF–3.7M
18.
Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a
Takeshi Miyatsuka, Yasuhiro Kosaka, Hail Kim, Michael S. German
Proc Natl Acad Sci U S A. 2011 Jan 4; 108(1): 185–190. Published online 2010 Dec 20. doi: 10.1073/pnas.1004842108
PMCID:
PMC3017196
ArticlePDF–945K
19.
Opposing actions of Arx and Pax4 in endocrine pancreas development
Patrick Collombat, Ahmed Mansouri, Jacob Hecksher-Sørensen, Palle Serup, Jens Krull, Gerard Gradwohl, Peter Gruss
Genes Dev. 2003 Oct 15; 17(20): 2591–2603. doi: 10.1101/gad.269003
PMCID:
PMC218152
ArticlePDF–811K
20.
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
Gérard Gradwohl, Andrée Dierich, Marianne LeMeur, François Guillemot
Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4): 1607–1611. doi: 10.1073/pnas.97.4.1607
PMCID:
PMC26482
ArticlePDF–863K

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