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Select item 107461431.

PAK3 downregulation induces cognitive impairment following cranial irradiation

Haksoo Lee, Hyunkoo Kang, Changjong Moon, BuHyun Youn

eLife. 2023; 12: RP89221. Published online 2023 Dec 22. doi: 10.7554/eLife.89221

PMCID:: PMC10746143

Article PDF–6.9M

Select item 86161032.

Disruption of PAK3 Signaling in Social Interaction Induced cFos Positive Cells Impairs Social Recognition Memory

Susan Zhou, Zhengping Jia

Cells. 2021 Nov; 10(11): 3010. Published online 2021 Nov 4. doi: 10.3390/cells10113010

PMCID:: PMC8616103

Article PDF–6.5M

Select item 67254203.

Abnormal Long-Lasting Synaptic Plasticity and Cognition in Mice Lacking the Mental Retardation Gene Pak3

Jinsong Meng, Yanghong Meng, Amanda Hanna, Christopher Janus, Zhengping Jia

J Neurosci. 2005 Jul 13; 25(28): 6641–6650. doi: 10.1523/JNEUROSCI.0028-05.2005

PMCID:: PMC6725420

Article PDF–619K

Select item 66210694.

Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

Aline Dubos, Gaelle Combeau, Yann Bernardinelli, Jean-Vianney Barnier, Oliver Hartley, Hubert Gaertner, Bernadett Boda, Dominique Muller

J Neurosci. 2012 Jan 11; 32(2): 519–527. doi: 10.1523/JNEUROSCI.3252-11.2012

PMCID:: PMC6621069

Article PDF–1.8M

Select item 34362655.

The p21-activated Kinase PAK3 Forms Heterodimers with PAK1 in Brain Implementing Trans-regulation of PAK3 Activity

Gaëlle Combeau, Patricia Kreis, Florence Domenichini, Muriel Amar, Philippe Fossier, Véronique Rousseau, Jean-Vianney Barnier

J Biol Chem. 2012 Aug 31; 287(36): 30084–30096. Published online 2012 Jul 19. doi: 10.1074/jbc.M112.355073

PMCID:: PMC3436265

Article PDF–1.7M

Select item 67302026.

The Mental Retardation Protein PAK3 Contributes to Synapse Formation and Plasticity in Hippocampus

Bernadett Boda, Stefano Alberi, Irina Nikonenko, Roxanne Node-Langlois, Pascal Jourdain, Marlyse Moosmayer, Lorena Parisi-Jourdain, Dominique Muller

J Neurosci. 2004 Dec 1; 24(48): 10816–10825. doi: 10.1523/JNEUROSCI.2931-04.2004

PMCID:: PMC6730202

Article PDF–563K

Select item 36128577.

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment

Adrienne M. Dorrance, Serena De Vita, Maria Radu, Pavankumar N. G. Reddy, Meaghan K. McGuinness, Chad E. Harris, Ronald Mathieu, Steven W. Lane, Rachelle Kosoff, Michael D. Milsom, Jonathan Chernoff, David A. Williams

Blood. 2013 Mar 28; 121(13): 2474–2482. Prepublished online 2013 Jan 18. doi: 10.1182/blood-2012-10-460709

PMCID:: PMC3612857

Article

Select item 1369488.

XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis

Jacob Souopgui, Marion Sölter, Tomas Pieler

EMBO J. 2002 Dec 2; 21(23): 6429–6439. doi: 10.1093/emboj/cdf644

PMCID:: PMC136948

Article PDF–479K

Select item 37430449.

Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling

Jakob Vowinckel, Silke Stahlberg, Nils Paulmann, Katharina Bluemlein, Maik Grohmann, Markus Ralser, Diego J. Walther

FEBS Lett. 2012 Nov 2; 586(21): 3819–3824. doi: 10.1016/j.febslet.2012.09.027

PMCID:: PMC3743044

Article PDF–757K

Select item 302863010.

p21-Activated Kinases 1 and 3 Control Brain Size through Coordinating Neuronal Complexity and Synaptic Properties

Wayne Huang, Zikai Zhou, Suhail Asrar, Mark Henkelman, Wei Xie, Zhengping Jia

Mol Cell Biol. 2011 Feb; 31(3): 388–403. Published online 2010 Nov 29. doi: 10.1128/MCB.00969-10

PMCID:: PMC3028630

Article PDF–6.1M

Select item 279135711.

CHL1 COOPERATES WITH PAK1-3 TO REGULATE MORPHOLOGICAL DIFFERENTIATION OF EMBYRONIC CORTICAL NEURONS

Galina P. Demyanenko, Ari I. Halberstadt, R. Sarada Rao, Patricia F. Maness

Neuroscience. Author manuscript; available in PMC 2011 Jan 13.

Published in final edited form as: Neuroscience. 2010 Jan 13; 165(1): 107–115. Published online 2009 Oct 9. doi: 10.1016/j.neuroscience.2009.09.077

PMCID:: PMC2791357

Article PDF–3.0M

Select item 607781412.

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1

Vitaliy V Bondar, Carolyn J Adamski, Tarik S Onur, Qiumin Tan, Li Wang, Javier Diaz-Garcia, Jeehye Park, Harry T Orr, Juan Botas, Huda Y Zoghbi

Hum Mol Genet. 2018 Aug 15; 27(16): 2863–2873. Published online 2018 May 30. doi: 10.1093/hmg/ddy200

PMCID:: PMC6077814

Article PDF–1.1M

Select item 835788813.

Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

Xiaohong Tan, Lu Tong, Lin Li, Jinjin Xu, Shaofang Xie, Lei Ji, Junjiang Fu, Qingwu Liu, Shihui Shen, Yun Liu, Yanhui Xiao, Feiran Gao, Robb E. Moses, Nabeel Bardeesy, Yanxiao Wang, Jishuai Zhang, Longying Tang, Lei Li, Kwok-kin Wong, Dianwen Song, Xiao Yang, Jian Liu, Xiaotao Li

Nat Commun. 2021; 12: 4853. Published online 2021 Aug 11. doi: 10.1038/s41467-021-24898-9

PMCID:: PMC8357888

Article PDF–8.9M

Select item 782173114.

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons

Kazuhiro Hada, Bolati Wulaer, Taku Nagai, Norimichi Itoh, Masahito Sawahata, Akira Sobue, Hiroyuki Mizoguchi, Daisuke Mori, Itaru Kushima, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada

Mol Brain. 2021; 14: 21. Published online 2021 Jan 22. doi: 10.1186/s13041-021-00735-4

PMCID:: PMC7821731

Article PDF–2.8M

Select item 361930215.

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

Bridget M. Dolan, Sergio G. Duron, David A. Campbell, Benedikt Vollrath, B. S. Shankaranarayana Rao, Hui-Yeon Ko, Gregory G. Lin, Arvind Govindarajan, Se-Young Choi, Susumu Tonegawa

Proc Natl Acad Sci U S A. 2013 Apr 2; 110(14): 5671–5676. Published online 2013 Mar 18. doi: 10.1073/pnas.1219383110

PMCID:: PMC3619302

Article PDF–454K

Select item 447202016.

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis

Fanny Jaudon, Fabrice Raynaud, Rosine Wehrlé, Jean-Michel Bellanger, Mohamed Doulazmi, Guilan Vodjdani, Stéphane Gasman, Laurent Fagni, Isabelle Dusart, Anne Debant, Susanne Schmidt

Mol Biol Cell. 2015 Jun 1; 26(11): 2112–2127. doi: 10.1091/mbc.E14-08-1310

PMCID:: PMC4472020

Article PDF–3.2M

Select item 265143017.

Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture

Yongjuan Chen, Richard J.W. Stump, Frank J. Lovicu, Akihiko Shimono, John W. McAvoy

Dev Biol. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Dev Biol. 2008 Dec 1; 324(1): 161–176. Published online 2008 Sep 18. doi: 10.1016/j.ydbio.2008.09.002

PMCID:: PMC2651430

Article PDF–7.3M

Select item 901661918.

SIRT1 regulates cardiomyocyte alignment during maturation

Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K. Janoshazi, David C. Fargo, Xiaoling Li

J Cell Sci. 2022 Apr 1; 135(7): jcs259076. Published online 2022 Apr 1. doi: 10.1242/jcs.259076

PMCID:: PMC9016619

Article

Select item 688915519.

Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex

Jie Liu, Yanfeng Liu, Jiaxiang Shao, Yisheng Li, Lixia Qin, Hailian Shen, Yunli Xie, Weiliang Xia, Wei-Qiang Gao

Cell Death Differ. 2019 Nov; 26(11): 2479–2492. Published online 2019 Mar 11. doi: 10.1038/s41418-019-0314-9

PMCID:: PMC6889155

Article PDF–6.3M

Select item 617601020.

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice

Chengwen Zhu, Cheng Cheng, Yanfei Wang, Waqas Muhammad, Shuang Liu, Weijie Zhu, Buwei Shao, Zhong Zhang, Xiaoqian Yan, Qingqing He, Zhengrong Xu, Chenjie Yu, Xiaoyun Qian, Ling Lu, Shasha Zhang, Yuan Zhang, Wei Xiong, Xia Gao, Zhigang Xu, Renjie Chai

Front Mol Neurosci. 2018; 11: 362. Published online 2018 Oct 2. doi: 10.3389/fnmol.2018.00362