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Select item 104365561.

Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1

Yaoyao Xue, Lang Pan, Spiros Vlahopoulos, Ke Wang, Xu Zheng, Zsolt Radak, Attila Bacsi, Lloyd Tanner, Allan R. Brasier, Xueqing Ba, Istvan Boldogh

Front Immunol. 2023; 14: 1161160. Published online 2023 Aug 4. doi: 10.3389/fimmu.2023.1161160

PMCID:: PMC10436556

Article PDF–10M

Select item 99436612.

8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury

Lang Pan, Wenjing Hao, Yaoyao Xue, Ke Wang, Xu Zheng, Jixian Luo, Xueqing Ba, Yang Xiang, Xiaoqun Qin, Jesper Bergwik, Lloyd Tanner, Arne Egesten, Allan R Brasier, Istvan Boldogh

Nucleic Acids Res. 2023 Feb 22; 51(3): 1087–1102. Published online 2023 Jan 18. doi: 10.1093/nar/gkac1241

PMCID:: PMC9943661

Article PDF–19M

Select item 84652443.

Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan

Maria Teresa Russo, Gabriele De Luca, Nieves Palma, Paola Leopardi, Paolo Degan, Serena Cinelli, Gaetano Pepe, Pasquale Mosesso, Emma Di Carlo, Carlo Sorrentino, Piero Musiani, Riccardo Crebelli, Margherita Bignami, Eugenia Dogliotti

Int J Mol Sci. 2021 Sep; 22(18): 9687. Published online 2021 Sep 7. doi: 10.3390/ijms22189687

PMCID:: PMC8465244

Article PDF–3.5M

Select item 78657434.

A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis

Sai Santosh Babu Komakula, Bhavya Blaze, Hong Ye, Agnieszka Dobrzyn, Harini Sampath

Int J Mol Sci. 2021 Feb; 22(3): 1152. Published online 2021 Jan 25. doi: 10.3390/ijms22031152

PMCID:: PMC7865743

Article PDF–2.6M

Select item 75419205.

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

Gantsetseg Tumurkhuu, Shuang Chen, Erica N. Montano, Duygu Ercan Laguna, Gabriela De Los Santos, Jeong Min Yu, Malcolm Lane, Michifumi Yamashita, Janet L. Markman, Luz P. Blanco, Mariana J. Kaplan, Kenichi Shimada, Timothy R. Crother, Mariko Ishimori, Daniel J. Wallace, Caroline A. Jefferies, Moshe Arditi

Front Immunol. 2020; 11: 554725. Published online 2020 Sep 24. doi: 10.3389/fimmu.2020.554725

PMCID:: PMC7541920

Article PDF–2.4M

Select item 75417426.

Small Molecule Inhibitor of 8-oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during P. aeruginosa Infection

Shugang Qin, Ping Lin, Qun Wu, Qinqin Pu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Ashley Gao, Madison Overby, Jinliang Yang, Jianxin Jiang, David L. Wilson, Yu-ki Tahara, Eric T. Kool, Zhenwei Xia, Min Wu

J Immunol. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: J Immunol. 2020 Oct 15; 205(8): 2231–2242. Published online 2020 Sep 14. doi: 10.4049/jimmunol.1901533

PMCID:: PMC7541742

Article PDF–2.3M

Select item 69595837.

OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model

Holly Simon, Vladimir Vartanian, Melissa H. Wong, Yusaku Nakabeppu, Priyanka Sharma, R. Stephen Lloyd, Harini Sampath

PLoS One. 2020; 15(1): e0227501. Published online 2020 Jan 14. doi: 10.1371/journal.pone.0227501

PMCID:: PMC6959583

Article PDF–2.4M

Select item 69398618.

Roles of OGG1 in Transcriptional Regulation and Maintenance of Metabolic Homeostasis

Harini Sampath, R. Stephen Lloyd

DNA Repair (Amst) Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: DNA Repair (Amst). 2019 Sep; 81: 102667. Published online 2019 Jul 8. doi: 10.1016/j.dnarep.2019.102667

PMCID:: PMC6939861

Article PDF–563K

Select item 66708729.

Oxoguanine Glycosylase 1 Protects Against Methamphetamine-Enhanced Fetal Brain Oxidative DNA Damage and Neurodevelopmental Deficits

Andrea W. Wong, Gordon P. McCallum, Winnie Jeng, Peter G. Wells

J Neurosci. 2008 Sep 3; 28(36): 9047–9054. doi: 10.1523/JNEUROSCI.2557-08.2008

PMCID:: PMC6670872

Article PDF–362K

Select item 662316010.

Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate

Wei Wang, Ying Esbensen, David Kunke, Rajikala Suganthan, Lyudmila Rachek, Magnar Bjørås, Lars Eide

J Neurosci. 2011 Jun 29; 31(26): 9746–9751. doi: 10.1523/JNEUROSCI.0852-11.2011

PMCID:: PMC6623160

Article PDF–1.2M

Select item 617374311.

The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue

Sai Santosh Babu Komakula, Jana Tumova, Deeptha Kumaraswamy, Natalie Burchat, Vladimir Vartanian, Hong Ye, Agnieszka Dobrzyn, R. Stephen Lloyd, Harini Sampath

Sci Rep. 2018; 8: 14886. Published online 2018 Oct 5. doi: 10.1038/s41598-018-33151-1

PMCID:: PMC6173743

Article PDF–2.4M

Select item 600912312.

Lack of the DNA Repair Enzyme OGG1 Sensitizes Dopamine Neurons to Manganese Toxicity During Development

Fernando Cardozo-Pelaez, David P. Cox, Celeste Bolin

Gene Expr. 2005; 12(4-6): 315–323. Published online 2018 Jun 20. doi: 10.3727/000000005783992007

PMCID:: PMC6009123

Article PDF–126K

Select item 599115613.

Strain-Specific Differences in the Expression and Activity of Ogg1 in the CNS

Diana I. Mosquera, Todd Stedeford, Fernando Cardozo-Pelaez, Juan Sanchez-Ramos

Gene Expr. 2003; 11(1): 47–53. Published online 2018 Jun 7. doi: 10.3727/000000003783992333

PMCID:: PMC5991156

Article PDF–148K

Select item 596732114.

OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

Ruoxi Wang, Chunshuang Li, Ping Qiao, Yaoyao Xue, Xu Zheng, Hongyu Chen, Xianlu Zeng, Wenguang Liu, Istvan Boldogh, Xueqing Ba

Cell Death Dis. 2018 Jun; 9(6): 628. Published online 2018 May 24. doi: 10.1038/s41419-018-0680-0

PMCID:: PMC5967321

Article PDF–2.8M

Select item 557818815.

Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis

Anna Kakehashi, Naomi Ishii, Takahiro Okuno, Masaki Fujioka, Min Gi, Hideki Wanibuchi

Int J Mol Sci. 2017 Aug; 18(8): 1801. Published online 2017 Aug 18. doi: 10.3390/ijms18081801

PMCID:: PMC5578188

Article PDF–2.5M

Select item 551920716.

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Vladimir Vartanian, Jana Tumova, Pawel Dobrzyn, Agnieszka Dobrzyn, Yusaku Nakabeppu, R. Stephen Lloyd, Harini Sampath

PLoS One. 2017; 12(7): e0181687. Published online 2017 Jul 20. doi: 10.1371/journal.pone.0181687

PMCID:: PMC5519207

Article PDF–2.2M

Select item 515951117.

O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts

Federico Cividini, Brian T. Scott, Anzhi Dai, Wenlong Han, Jorge Suarez, Julieta Diaz-Juarez, Tanja Diemer, Darren E. Casteel, Wolfgang H. Dillmann

J Biol Chem. 2016 Dec 16; 291(51): 26515–26528. Published online 2016 Nov 5. doi: 10.1074/jbc.M116.754481

PMCID:: PMC5159511

Article PDF–4.2M

Select item 501172818.

Gamma radiation at a human relevant low dose rate is genotoxic in mice

Anne Graupner, Dag M. Eide, Christine Instanes, Jill M. Andersen, Dag A. Brede, Stephen D. Dertinger, Ole C. Lind, Anicke Brandt-Kjelsen, Hans Bjerke, Brit Salbu, Deborah Oughton, Gunnar Brunborg, Ann K. Olsen

Sci Rep. 2016; 6: 32977. Published online 2016 Sep 6. doi: 10.1038/srep32977

PMCID:: PMC5011728

Article PDF–1010K

Select item 442286819.

Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B₁ tumourigenicity in mice

Jeanne E. Mulder, Patricia V. Turner, Thomas E. Massey

Mutagenesis. 2015 May; 30(3): 401–409. Published online 2015 Jan 11. doi: 10.1093/mutage/geu087

PMCID:: PMC4422868

Article PDF–4.7M

Select item 437025320.

Asbestos-Induced Pulmonary Fibrosis Is Augmented in 8-Oxoguanine DNA Glycosylase Knockout Mice

Paul Cheresh, Luisa Morales-Nebreda, Seok-Jo Kim, Anjana Yeldandi, David B. Williams, Yuan Cheng, Gökhan M. Mutlu, G. R. Scott Budinger, Karen Ridge, Paul T. Schumacker, Vilhelm A. Bohr, David W. Kamp

Am J Respir Cell Mol Biol. 2015 Jan; 52(1): 25–36. doi: 10.1165/rcmb.2014-0038OC