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Items: 1 to 20 of 38

1.
Conditional deletion of Neurexin-2 alters neuronal network activity in hippocampal circuitries and leads to spontaneous seizures
Mulatwa T. Haile, Sheraz Khoja, Gregory de Carvalho, Robert F. Hunt, Lulu Y. Chen
Transl Psychiatry. 2023; 13: 97. Published online 2023 Mar 20. doi: 10.1038/s41398-023-02394-6
PMCID:
PMC10027846
ArticlePDF–4.3M
2.
Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus
Pei-Yi Lin, Lulu Y. Chen, Man Jiang, Justin H. Trotter, Erica Seigneur, Thomas C. Südhof
Sci Adv. 2023 Jan; 9(1): eadd8856. Published online 2023 Jan 6. doi: 10.1126/sciadv.add8856
PMCID:
PMC9821874
ArticlePDF–1.8M
3.
Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors
Gesche Born, Hannah M. Grayton, Hanna Langhorst, Irina Dudanova, Astrid Rohlmann, Benjamin W. Woodward, David A. Collier, Cathy Fernandes, Markus Missler
Front Synaptic Neurosci. 2015; 7: 3. Published online 2015 Feb 19. doi: 10.3389/fnsyn.2015.00003
PMCID:
PMC4333794
ArticlePDF–3.2M
4.
Heterozygous Deletion of α-Neurexin I or α-Neurexin II Results in Behaviors Relevant to Autism and Schizophrenia
James Dachtler, Jose L. Ivorra, Tessa E. Rowland, Colin Lever, R. John Rodgers, Steven J. Clapcote
Behav Neurosci. 2015 Dec; 129(6): 765–776. doi: 10.1037/bne0000108
PMCID:
PMC4655861
ArticlePDF–718K
5.
Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization
Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi
Front Mol Neurosci. 2024; 17: 1371145. Published online 2024 Mar 20. doi: 10.3389/fnmol.2024.1371145
PMCID:
PMC10989685
ArticlePDF–11M
6.
Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion
Rebecca B Hughes, Jayde Whittingham-Dowd, Rachel E Simmons, Steven J Clapcote, Susan J Broughton, Neil Dawson
Cereb Cortex. 2020 Apr; 30(4): 2358–2371. Published online 2019 Dec 8. doi: 10.1093/cercor/bhz244
PMCID:
PMC7175007
ArticlePDF–1.0M
7.
Important Contribution of α-Neurexins to Ca2+-Triggered Exocytosis of Secretory Granules
Irina Dudanova, Simon Sedej, Mohiuddin Ahmad, Henriette Masius, Vardanush Sargsyan, Weiqi Zhang, Dietmar Riedel, Frank Angenstein, Detlev Schild, Marjan Rupnik, Markus Missler
J Neurosci. 2006 Oct 11; 26(41): 10599–10613. doi: 10.1523/JNEUROSCI.1913-06.2006
PMCID:
PMC6674690
ArticlePDF–2.4M
8.
Neurexins are differentially expressed in the embryonic nervous system of mice
AW Puschel, H Betz
J Neurosci. 1995 Apr 1; 15(4): 2849–2856. doi: 10.1523/JNEUROSCI.15-04-02849.1995
PMCID:
PMC6577774
AbstractPDF–2.5M
9.
Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA- and AMPA-Receptor Responses
Jinye Dai, Jason Aoto, Thomas C. Sudhof
Neuron. Author manuscript; available in PMC 2020 Jun 5.
Published in final edited form as: Neuron. 2019 Jun 5; 102(5): 993–1008.e5. Published online 2019 Apr 17. doi: 10.1016/j.neuron.2019.03.032
Correction in:
Neuron. 2024 Feb 7; 112(3): 515–519.
PMCID:
PMC6554035
ArticlePDF–3.8M
10.
The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice
Eleftheria Pervolaraki, Adam L. Tyson, Francesca Pibiri, Steven L. Poulter, Amy C. Reichelt, R. John Rodgers, Steven J. Clapcote, Colin Lever, Laura C. Andreae, James Dachtler
Mol Autism. 2019; 10: 8. Published online 2019 Feb 28. doi: 10.1186/s13229-019-0261-9
PMCID:
PMC6394023
ArticlePDF–3.4M
11.
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice
Jordano Brito-Moreira, Mychael V. Lourenco, Mauricio M. Oliveira, Felipe C. Ribeiro, José Henrique Ledo, Luan P. Diniz, Juliana F. S. Vital, Margaret H. Magdesian, Helen M. Melo, Fernanda Barros-Aragão, Jorge M. de Souza, Soniza V. Alves-Leon, Flavia C. A. Gomes, Julia R. Clarke, Cláudia P. Figueiredo, Fernanda G. De Felice, Sergio T. Ferreira
J Biol Chem. 2017 May 5; 292(18): 7327–7337. Published online 2017 Mar 10. doi: 10.1074/jbc.M116.761189
PMCID:
PMC5418035
ArticlePDF–2.7M
12.
Deletion of α-neurexin II results in autism-related behaviors in mice
J Dachtler, J Glasper, R N Cohen, J L Ivorra, D J Swiffen, A J Jackson, M K Harte, R J Rodgers, S J Clapcote
Transl Psychiatry. 2014 Nov; 4(11): e484. Published online 2014 Nov 25. doi: 10.1038/tp.2014.123
PMCID:
PMC4259993
ArticlePDF–1.1M
13.
Neurexins regulate presynaptic GABAB-receptors at central synapses
Fujun Luo, Alessandra Sclip, Sean Merrill, Thomas C. Südhof
Nat Commun. 2021; 12: 2380. Published online 2021 Apr 22. doi: 10.1038/s41467-021-22753-5
PMCID:
PMC8062527
ArticlePDF–5.6M
14.
Autism-associated miR-873 regulates ARID1B, SHANK3 and NRXN2 involved in neurodevelopment
Jing Lu, Yan Zhu, Sarah Williams, Michelle Watts, Mary A. Tonta, Harold A. Coleman, Helena C. Parkington, Charles Claudianos
Transl Psychiatry. 2020; 10: 418. Published online 2020 Dec 1. doi: 10.1038/s41398-020-01106-8
PMCID:
PMC7708977
ArticlePDF–2.9M
15.
Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism
Anna J. Khalaj, Fredrik H. Sterky, Alessandra Sclip, Jochen Schwenk, Axel T. Brunger, Bernd Fakler, Thomas C. Südhof
J Cell Biol. 2020 Sep 7; 219(9): e202004164. Published online 2020 Jul 24. doi: 10.1083/jcb.202004164
PMCID:
PMC7480106
ArticlePDF–9.1M
16.
Neurexins cluster Ca2+ channels within the presynaptic active zone
Fujun Luo, Alessandra Sclip, Man Jiang, Thomas C Südhof
EMBO J. 2020 Apr 1; 39(7): e103208. Published online 2020 Mar 5. doi: 10.15252/embj.2019103208
PMCID:
PMC7110102
ArticlePDF–3.4M
17.
β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling
Garret R. Anderson, Jason Aoto, Katsuhiko Tabuchi, Csaba Földy, Jason Covy, Ada Xin Yee, Dick Wu, Sung-Jin Lee, Lu Chen, Robert C. Malenka, Thomas C. Südhof
Cell. Author manuscript; available in PMC 2016 Jul 30.
Published in final edited form as: Cell. 2015 Jul 30; 162(3): 593–606. Published online 2015 Jul 23. doi: 10.1016/j.cell.2015.06.056
PMCID:
PMC4709013
ArticlePDF–1.4M
18.
Postsynaptic N-methyl-d-aspartate receptor function requires α-neurexins
Gunnar Kattenstroth, Evangelia Tantalaki, Thomas C. Südhof, Kurt Gottmann, Markus Missler
Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8): 2607–2612. Published online 2004 Feb 13. doi: 10.1073/pnas.0308626100
PMCID:
PMC356997
ArticlePDF–442K
19.
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth T. C. Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler, Fahmeed Hyder, Thomas Biederer
Nat Commun. 2023; 14: 459. Published online 2023 Jan 28. doi: 10.1038/s41467-023-36042-w
PMCID:
PMC9884278
ArticlePDF–4.0M
20.
Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins
Lulu Y. Chen, Man Jiang, Bo Zhang, Ozgun Gokce, Thomas C. Südhof
Neuron. Author manuscript; available in PMC 2018 May 3.
Published in final edited form as: Neuron. 2017 May 3; 94(3): 611–625.e4. doi: 10.1016/j.neuron.2017.04.011
PMCID:
PMC5501922
ArticlePDF–1.6M

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