PMC Links for Gene (Select 18115) - PMC

Aimee E. Vozenilek, Matthew Vetkoetter, Jonette M. Green, Xinggui Shen, James G. Traylor, Ronald L. Klein, A. Wayne Orr, Matthew D. Woolard, David M. Krzywanski

J Vasc Res. Author manuscript; available in PMC 2019 Feb 16.

Published in final edited form as: J Vasc Res. 2018; 55(2): 98–110. Published online 2018 Feb 16. doi: 10.1159/000486337

PMCID:: PMC6287760

Article PDF–909K

Select item 54441114.

NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells

Laila R.B. Santos, Carole Muller, Arnaldo H. de Souza, Hilton K. Takahashi, Peter Spégel, Ian R. Sweet, Heeyoung Chae, Hindrik Mulder, Jean-Christophe Jonas

Mol Metab. 2017 Jun; 6(6): 535–547. Published online 2017 Apr 21. doi: 10.1016/j.molmet.2017.04.004

PMCID:: PMC5444111

Article PDF–2.8M

Select item 50257005.

The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria

Juliana Aparecida Ronchi, Annelise Francisco, Luiz Augusto Correa Passos, Tiago Rezende Figueira, Roger Frigério Castilho

J Biol Chem. 2016 Sep 16; 291(38): 20173–20187. Published online 2016 Jul 29. doi: 10.1074/jbc.M116.730473

PMCID:: PMC5025700

Article PDF–2.7M

Select item 44426976.

Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy consuming redox circuit

Kelsey H. Fisher-Wellman, Chien-Te Lin, Terence E. Ryan, Lauren R. Reese, Laura A. A. Gilliam, Brook L. Cathey, Daniel S. Lark, Cody D. Smith, Deborah M. Muoio, P. Darrell Neufer

Biochem J. Author manuscript; available in PMC 2016 Apr 15.

Published in final edited form as: Biochem J. 2015 Apr 15; 467(2): 271–280. doi: 10.1042/BJ20141447

PMCID:: PMC4442697

Article PDF–1.5M

Select item 37637677.

Differences in the Degree of Cerulein-Induced Chronic Pancreatitis in C57BL/6 Mouse Substrains Lead to New Insights in Identification of Potential Risk Factors in the Development of Chronic Pancreatitis

Barbara Ulmasov, Kiyoko Oshima, Michael G. Rodriguez, Roger D. Cox, Brent A. Neuschwander-Tetri

Am J Pathol. 2013 Sep; 183(3): 692–708. doi: 10.1016/j.ajpath.2013.05.020

PMCID:: PMC3763767

Article PDF–1.5M

Select item 36423398.

Cofactor Balance by Nicotinamide Nucleotide Transhydrogenase (NNT) Coordinates Reductive Carboxylation and Glucose Catabolism in the Tricarboxylic Acid (TCA) Cycle

Paulo A. Gameiro, Laura A. Laviolette, Joanne K. Kelleher, Othon Iliopoulos, Gregory Stephanopoulos

J Biol Chem. 2013 May 3; 288(18): 12967–12977. Published online 2013 Mar 15. doi: 10.1074/jbc.M112.396796

PMCID:: PMC3642339

Article PDF–2.2M

Select item 73996859.

Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart

Michael Wagner, Edoardo Bertero, Alexander Nickel, Michael Kohlhaas, Gary E. Gibson, Ward Heggermont, Stephane Heymans, Christoph Maack

Basic Res Cardiol. 2020; 115(5): 53. Published online 2020 Aug 3. doi: 10.1007/s00395-020-0815-1

PMCID:: PMC7399685

Article PDF–2.4M

Select item 710342510.

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not

Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Joaquin Botta, Eirini Meimaridou, Avinaash V Maharaj, Michelle Stewart, Andrew Tinker, Roger D Cox, Lou A Metherell

Life Sci Alliance. 2020 Apr; 3(4): e201900593. Published online 2020 Mar 25. doi: 10.26508/lsa.201900593

PMCID:: PMC7103425

Article PDF–3.2M

Select item 636145011.

Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance

Pamela A. Kakimoto, Bruno Chausse, Camille C. Caldeira da Silva, José Donato Júnior, Alicia J. Kowaltowski

PLoS One. 2019; 14(2): e0211733. Published online 2019 Feb 4. doi: 10.1371/journal.pone.0211733

PMCID:: PMC6361450

Article PDF–2.6M

Select item 609333512.

Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma

Vasileios Chortis, Angela E Taylor, Craig L Doig, Mark D Walsh, Eirini Meimaridou, Carl Jenkinson, Giovanny Rodriguez-Blanco, Cristina L Ronchi, Alisha Jafri, Louise A Metherell, Daniel Hebenstreit, Warwick B Dunn, Wiebke Arlt, Paul A Foster

Endocrinology. 2018 Aug; 159(8): 2836–2849. Published online 2018 Apr 20. doi: 10.1210/en.2018-00014

PMCID:: PMC6093335

Article

Select item 592694113.

Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease

Maria E. Moreno-Fernandez, Daniel A. Giles, Traci E. Stankiewicz, Rachel Sheridan, Rebekah Karns, Monica Cappelletti, Kristin Lampe, Rajib Mukherjee, Christian Sina, Anthony Sallese, James P. Bridges, Simon P. Hogan, Bruce J. Aronow, Kasper Hoebe, Senad Divanovic

JCI Insight. 2018 Mar 22; 3(6): e93626. Published online 2018 Mar 22. doi: 10.1172/jci.insight.93626

PMCID:: PMC5926941

Article PDF–2.6M

Select item 574455914.

NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice

E Meimaridou, M Goldsworthy, V Chortis, E Fragouli, P A Foster, W Arlt, R Cox, L A Metherell

J Endocrinol. 2018 Jan; 236(1): 13–28. Published online 2017 Oct 18. doi: 10.1530/JOE-16-0638

PMCID:: PMC5744559

Article PDF–2.3M

Select item 513197815.

The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome

Monica Llano-Diez, Jon Sinclair, Takashi Yamada, Mei Zong, Jeremy Fauconnier, Shi-Jin Zhang, Abram Katz, Kent Jardemark, Håkan Westerblad, Daniel C. Andersson, Johanna T. Lanner

PLoS One. 2016; 11(12): e0167090. Published online 2016 Dec 1. doi: 10.1371/journal.pone.0167090

PMCID:: PMC5131978

Article PDF–1.4M

Select item 327619016.

The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2

Stefanie J. Navarro, Tuyen Trinh, Charlotte A. Lucas, Andrea J. Ross, Katrina G. Waymire, Grant R. MacGregor

G3 (Bethesda) 2012 Jan; 2(1): 99–102. Published online 2012 Jan 1. doi: 10.1534/g3.111.000778

PMCID:: PMC3276190

Article PDF–561K

Select item 274156617.

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2

Nadeene Parker, Antonio J. Vidal-Puig, Vian Azzu, Martin D. Brand

Biochim Biophys Acta. 2009 Dec; 1787(12): 1451–1457. doi: 10.1016/j.bbabio.2009.06.005

PMCID:: PMC2741566

Article

Select item 264281818.

Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt

Abraham A Anderson, Joan Helmering, Todd Juan, Chi-Ming Li, Jocelyn McCormick, Melissa Graham, Daniel M Baker, Michael A Damore, Murielle M Véniant, David J Lloyd

Pathogenetics. 2009; 2: 1. Published online 2009 Jan 22. doi: 10.1186/1755-8417-2-1

PMCID:: PMC2642818

Article PDF–457K

Select item 338689619.

Mutations in Nicotinamide Nucleotide Transhydrogenase (NNT) cause familial glucocorticoid deficiency

Eirini Meimaridou, Julia Kowalczyk, Leonardo Guasti, Claire R. Hughes, Florian Wagner, Peter Frommolt, Peter Nürnberg, Nicholas P. Mann, Ritwik Banerjee, H. Nurcin Saka, J. Paul Chapple, Peter J. King, Adrian J.L. Clark, Louise A. Metherell

Nat Genet. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Nat Genet. 2012 May 27; 44(7): 740–742. Published online 2012 May 27. doi: 10.1038/ng.2299