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Select item 99354971.

High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice

Sujuan Wang, Meichan Yang, Pei Li, Julian Sit, Audrey Wong, Kyle Rodrigues, Daniel Lank, Deqiang Zhang, Kezhong Zhang, Lei Yin, Xin Tong

Diabetes. 2023 Mar; 72(3): 348–361. Published online 2022 Dec 12. doi: 10.2337/db22-0332

PMCID:: PMC9935497

Article PDF–19M

Select item 92636482.

NFIL3 deficiency alleviates EAE through regulating different immune cell subsets

Zhigang Chen, Rong Fan, Jie Liang, Zexiu Xiao, Junlong Dang, Jun Zhao, Ruihui Weng, Cansheng Zhu, Song Guo Zheng, Ying Jiang

J Adv Res. 2022 Jul; 39: 225–235. Published online 2021 Nov 14. doi: 10.1016/j.jare.2021.10.011

PMCID:: PMC9263648

Article PDF–3.5M

Select item 80110303.

Hepatic E4BP4 induction promotes lipid accumulation by suppressing AMPK signaling in response to chemical or diet-induced ER stress

Meichan Yang, Deqiang Zhang, Zifeng Zhao, Julian Sit, Mischael Saint-Sume, Omar Shabandri, Kezhong Zhang, Lei Yin, Xin Tong

FASEB J. Author manuscript; available in PMC 2021 Mar 31.

Published in final edited form as: FASEB J. 2020 Oct; 34(10): 13533–13547. Published online 2020 Aug 11. doi: 10.1096/fj.201903292RR

PMCID:: PMC8011030

Article PDF–1.2M

Select item 58309254.

Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells

Tomohiro Miyai, Junichiro Takano, Takaho A. Endo, Eiryo Kawakami, Yasutoshi Agata, Yasutaka Motomura, Masato Kubo, Yukie Kashima, Yutaka Suzuki, Hiroshi Kawamoto, Tomokatsu Ikawa

Genes Dev. 2018 Jan 15; 32(2): 112–126. doi: 10.1101/gad.309575.117

PMCID:: PMC5830925

Article PDF–12M

Select item 56162095.

Lacrimal Gland NK Cells Are Developmentally and Functionally Similar to Conventional NK Cells

Timothy Erick, Lilit Grigoryan, Laurent Brossay

Immunohorizons. Author manuscript; available in PMC 2017 Sep 27.

Published in final edited form as: Immunohorizons. 2017 Apr 1; 1(2): 2–9. doi: 10.4049/immunohorizons.1700008

PMCID:: PMC5616209

Article PDF–624K

Select item 47592496.

The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy

Selma Boulenouar, Jean-Marc Doisne, Amanda Sferruzzi-Perri, Louise M. Gaynor, Jens Kieckbusch, Elisa Balmas, Hong Wa Yung, Shagayegh Javadzadeh, Léa Volmer, Delia A. Hawkes, Keli Phillips, Hugh J.M. Brady, Abigail L. Fowden, Graham J. Burton, Ashley Moffett, Francesco Colucci

Front Immunol. 2016; 7: 43. Published online 2016 Feb 19. doi: 10.3389/fimmu.2016.00043

PMCID:: PMC4759249

Article PDF–5.8M

Select item 35490887.

Natural killer cells promote immune tolerance by regulating inflammatory T_H17 cells at the human maternal–fetal interface

Binqing Fu, Xianchang Li, Rui Sun, Xianhong Tong, Bin Ling, Zhigang Tian, Haiming Wei

Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3): E231–E240. Published online 2012 Dec 27. doi: 10.1073/pnas.1206322110

PMCID:: PMC3549088

Article PDF–1.8M

Select item 30984838.

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

Masaki Kashiwada, Suzanne L Cassel, John D Colgan, Paul B Rothman

EMBO J. 2011 May 18; 30(10): 2071–2082. Published online 2011 Apr 15. doi: 10.1038/emboj.2011.111

PMCID:: PMC3098483

Article PDF–2.1M

Select item 29171519.

The Transcriptional Regulator NFIL3 Controls IgE Production

Paul B. Rothman

Trans Am Clin Climatol Assoc. 2010; 121: 156–171.

PMCID:: PMC2917151

Article PDF–69K

Select item 281894210.

IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

Masaki Kashiwada, Deborah M. Levy, Lisa McKeag, Keri Murray, Andreas J. Schröder, Stephen M. Canfield, Geri Traver, Paul B. Rothman

Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2): 821–826. Published online 2009 Dec 22. doi: 10.1073/pnas.0909235107

PMCID:: PMC2818942

Article PDF–1.0M

Select item 680264111.

The transcription factor NFIL3 controls regulatory T-cell function and stability

Hyeong Su Kim, Hyogon Sohn, Sung Woong Jang, Gap Ryol Lee

Exp Mol Med. 2019 Jul; 51(7): 80. Published online 2019 Jul 16. doi: 10.1038/s12276-019-0280-9

PMCID:: PMC6802641

Article PDF–2.3M

Select item 639002812.

NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology

Susan Schlenner, Emanuela Pasciuto, Vasiliki Lagou, Oliver Burton, Teresa Prezzemolo, Steffie Junius, Carlos P Roca, Cyril Seillet, Cynthia Louis, James Dooley, Kylie Luong, Erika Van Nieuwenhove, Ian P Wicks, Gabrielle Belz, Stéphanie Humblet-Baron, Carine Wouters, Adrian Liston

Ann Rheum Dis. 2019 Mar; 78(3): 342–349. Published online 2018 Dec 14. doi: 10.1136/annrheumdis-2018-213764

PMCID:: PMC6390028

Article PDF–7.4M

Select item 633700913.

Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency

Matthew T. Rätsep, Stephen D. Moore, Salema Jafri, Melissa Mitchell, Hugh J. M. Brady, Ofer Mandelboim, Mark Southwood, Nicholas W. Morrell, Francesco Colucci, Mark L. Ormiston

Am J Physiol Lung Cell Mol Physiol. 2018 Dec 1; 315(6): L977–L990. Published online 2018 Sep 20. doi: 10.1152/ajplung.00477.2017

PMCID:: PMC6337009

Article

Select item 534351914.

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development

Patrick Ming-Kuen Tang, Shuang Zhou, Xiao-Ming Meng, Qing-Ming Wang, Chun-Jie Li, Guang-Yu Lian, Xiao-Ru Huang, Yong-Jiang Tang, Xin-Yuan Guan, Bryan Ping-Yen Yan, Ka-Fai To, Hui-Yao Lan

Nat Commun. 2017; 8: 14677. Published online 2017 Mar 6. doi: 10.1038/ncomms14677

PMCID:: PMC5343519

Article PDF–3.2M

Select item 491885115.

E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis

Xin Tong, Pei Li, Deqiang Zhang, Kyle VanDommelen, Neil Gupta, Liangyou Rui, M. Bishr Omary, Lei Yin

J Lipid Res. 2016 Jul; 57(7): 1219–1230. doi: 10.1194/jlr.M067181

PMCID:: PMC4918851

Article PDF–1.2M

Select item 443897916.

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo

Loek R. van der Kallen, Ruben Eggers, Erich M. Ehlert, Joost Verhaagen, August B. Smit, Ronald E. van Kesteren

PLoS One. 2015; 10(5): e0127163. Published online 2015 May 20. doi: 10.1371/journal.pone.0127163

PMCID:: PMC4438979

Article PDF–4.6M

Select item 414473217.

Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens

Theresa L. Geiger, Michael C. Abt, Georg Gasteiger, Matthew A. Firth, Margaret H. O’Connor, Clair D. Geary, Timothy E. O’Sullivan, Marcel R. van den Brink, Eric G. Pamer, Alan M. Hanash, Joseph C. Sun

J Exp Med. 2014 Aug 25; 211(9): 1723–1731. doi: 10.1084/jem.20140212

PMCID:: PMC4144732

Article PDF–1.4M

Select item 394811218.

The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development

Stefania Crotta, Annita Gkioka, Victoria Male, João H. Duarte, Sophia Davidson, Ilaria Nisoli, Hugh J. M. Brady, Andreas Wack

J Immunol. 2014 Mar 15; 192(6): 2677–2688. Published online 2014 Feb 17. doi: 10.4049/jimmunol.1302765

PMCID:: PMC3948112

Article PDF–1.5M

Select item 389434219.

Neuroprotective Role of the Basic Leucine Zipper Transcription Factor NFIL3 in Models of Amyotrophic Lateral Sclerosis

So-ichi Tamai, Keisuke Imaizumi, Nobuhiro Kurabayashi, Minh Dang Nguyen, Takaya Abe, Masatoshi Inoue, Yoshitaka Fukada, Kamon Sanada

J Biol Chem. 2014 Jan 17; 289(3): 1629–1638. Published online 2013 Nov 26. doi: 10.1074/jbc.M113.524389

PMCID:: PMC3894342

Article PDF–3.4M

Select item 365022820.

Survival factor NFIL3 restricts FOXO-induced gene expression in cancer

Megan Keniry, Maira M. Pires, Sarah Mense, Celine Lefebvre, Boyi Gan, Karen Justiano, Ying-Ka Ingar Lau, Ben Hopkins, Cindy Hodakoski, Susan Koujak, Joseph Toole, Franklyn Fenton, Ashley Calahan, Andrea Califano, Ronald A. DePinho, Matt Maurer, Ramon Parsons

Genes Dev. 2013 Apr 15; 27(8): 916–927. doi: 10.1101/gad.214049.113