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Items: 1 to 20 of 65

1.
MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis
Hiroki Takahashi, Ge Yang, Takeshi Yoneshiro, Yohei Abe, Ryo Ito, Chaoran Yang, Junna Nakazono, Mayumi Okamoto-Katsuyama, Aoi Uchida, Makoto Arai, Hitomi Jin, Hyunmi Choi, Myagmar Tumenjargal, Shiyu Xie, Ji Zhang, Hina Sagae, Yanan Zhao, Rei Yamaguchi, Yu Nomura, Yuichi Shimizu, Kaito Yamada, Satoshi Yasuda, Hiroshi Kimura, Toshiya Tanaka, Youichiro Wada, Tatsuhiko Kodama, Hiroyuki Aburatani, Min-Sheng Zhu, Takeshi Inagaki, Timothy F. Osborne, Takeshi Kawamura, Yasushi Ishihama, Yoshihiro Matsumura, Juro Sakai
Nat Commun. 2022; 13: 5715. Published online 2022 Sep 29. doi: 10.1038/s41467-022-33363-0
PMCID:
PMC9523048
ArticlePDF–3.6M
2.
Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke
Hailan Meng, Lizhen Fan, Cun-Jin Zhang, Liwen Zhu, Pinyi Liu, Jian Chen, Xinyu Bao, Zhijun Pu, Min-Sheng Zhu, Yun Xu
iScience. 2021 Sep 24; 24(9): 103047. Published online 2021 Aug 28. doi: 10.1016/j.isci.2021.103047
PMCID:
PMC8441154
ArticlePDF–6.1M
3.
Augmented contractility of murine femoral arteries in a streptozotocin diabetes model is related to increased phosphorylation of MYPT1
Lubomir T. Lubomirov, Hristo Gagov, Mechthild M. Schroeter, Rudolf J. Wiesner, Andras Franko
Physiol Rep. 2019 Feb; 7(3): e13975. Published online 2019 Feb 10. doi: 10.14814/phy2.13975
PMCID:
PMC6369311
ArticlePDF–677K
4.
Localized myosin II activity regulates assembly and plasticity of the axon initial segment
Stephen L. Berger, Alejandra Leo-Macias, Stephanie Yuen, Latika Khatri, Sylvia Pfennig, Yanqing Zhang, Esperanza Agullo-Pascual, Ghislaine Caillol, Min–Sheng Zhu, Eli Rothenberg, Carmen V. Melendez-Vasquez, Mario Delmar, Christophe Leterrier, James L. Salzer
Neuron. Author manuscript; available in PMC 2019 Feb 7.
Published in final edited form as: Neuron. 2018 Feb 7; 97(3): 555–570.e6. Published online 2018 Jan 25. doi: 10.1016/j.neuron.2017.12.039
PMCID:
PMC5805619
ArticlePDF–1.4M
5.
A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading
John J. Reho, Doreswamy Kenchegowda, Laureano D. Asico, Steven A. Fisher
Am J Physiol Heart Circ Physiol. 2016 Jun 1; 310(11): H1715–H1724. Published online 2016 Apr 15. doi: 10.1152/ajpheart.00869.2015
PMCID:
PMC4935519
Article
6.
In vivo roles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction
Cai-Ping Chen, Xin Chen, Yan-Ning Qiao, Pei Wang, Wei-Qi He, Cheng-Hai Zhang, Wei Zhao, Yun-Qian Gao, Chen Chen, Tao Tao, Jie Sun, Ye Wang, Ning Gao, Kristine E Kamm, James T Stull, Min-Sheng Zhu
J Physiol. 2015 Feb 1; 593(Pt 3): 681–700. Published online 2014 Dec 23. doi: 10.1113/jphysiol.2014.283853
PMCID:
PMC4324713
ArticlePDF–1.7M
7.
Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle
Ming-Ho Tsai, Audrey N Chang, Jian Huang, Weiqi He, H Lee Sweeney, Minsheng Zhu, Kristine E Kamm, James T Stull
J Physiol. 2014 Jul 15; 592(Pt 14): 3031–3051. Published online 2014 May 16. doi: 10.1113/jphysiol.2014.273011
PMCID:
PMC4214658
ArticlePDF–1.1M
8.
Myosin Phosphatase Target Subunit 1 (MYPT1) Regulates the Contraction and Relaxation of Vascular Smooth Muscle and Maintains Blood Pressure
Yan-Ning Qiao, Wei-Qi He, Cai-Ping Chen, Cheng-Hai Zhang, Wei Zhao, Pei Wang, Lin Zhang, Yan-Ze Wu, Xiao Yang, Ya-Jing Peng, Ji-Min Gao, Kristine E. Kamm, James T. Stull, Min-Sheng Zhu
J Biol Chem. 2014 Aug 8; 289(32): 22512–22523. Published online 2014 Jun 20. doi: 10.1074/jbc.M113.525444
PMCID:
PMC4139257
ArticlePDF–2.5M
9.
Neural programming of mesenteric and renal arteries
John J. Reho, Xiaoxu Zheng, James E. Benjamin, Steven A. Fisher
Am J Physiol Heart Circ Physiol. 2014 Aug 15; 307(4): H563–H573. Published online 2014 Jun 14. doi: 10.1152/ajpheart.00250.2014
PMCID:
PMC4137124
Article
10.
Altered Contractile Phenotypes of Intestinal Smooth Muscle in Mice Deficient in Myosin Phosphatase Target Subunit 1
Wei–Qi He, Yan–Ning Qiao, Ya–Jing Peng, Juan–Min Zha, Cheng–Hai Zhang, Chen Chen, Cai–Ping Chen, Pei Wang, Xiao Yang, Chao–Jun Li, Kristine E. Kamm, James T. Stull, Min–Sheng Zhu
Gastroenterology. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: Gastroenterology. 2013 Jun; 144(7): 1456–1465.e5. Published online 2013 Mar 13. doi: 10.1053/j.gastro.2013.02.045
PMCID:
PMC3782749
ArticlePDF–5.2M
11.
MYPT1 reduction is a pathogenic factor of erectile dysfunction
Wei Zhao, Jie Sun, Liang-Yu Yao, Dong Hang, Ye-Qiong Li, Cai-Ping Chen, Yu-Wei Zhou, Xin Chen, Tao Tao, Li-Sha Wei, Yan-Yan Zheng, Xie Ge, Chao-Jun Li, Zhong-Cheng Xin, Yang Pan, Xin-Zhu Wang, Wei-Qi He, Xue-Na Zhang, Bing Yao, Min-Sheng Zhu
Commun Biol. 2022; 5: 744. Published online 2022 Jul 25. doi: 10.1038/s42003-022-03716-y
PMCID:
PMC9314386
ArticlePDF–3.3M
12.
O-GlcNAc modification of MYPT1 modulates lysophosphatidic acid–induced cell contraction in fibroblasts
Murielle M. Morales, Nichole J. Pedowitz, Matthew R. Pratt
J Biol Chem. 2021 Jan-Jun; 296: 100800. Published online 2021 May 19. doi: 10.1016/j.jbc.2021.100800
PMCID:
PMC8191289
ArticlePDF–2.6M
13.
MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease
W. Zhao, P. Wang, W. He, T. Tao, H. Li, Y. Li, W. Jiang, J. Sun, X. Ge, X. Chen, Y. Zheng, L. Wei, C. Chen, Y. Wang, C. Li, H. Chen, B. Yao, W. Tang, M. Zhu
Cell Mol Gastroenterol Hepatol. 2020; 9(2): 345–347.e6. Published online 2019 Nov 20. doi: 10.1016/j.jcmgh.2019.11.003
PMCID:
PMC6997446
ArticlePDF–3.0M
14.
The molecular basis of the genesis of basal tone in internal anal sphincter
Cheng-Hai Zhang, Pei Wang, Dong-Hai Liu, Cai-Ping Chen, Wei Zhao, Xin Chen, Chen Chen, Wei-Qi He, Yan-Ning Qiao, Tao Tao, Jie Sun, Ya-Jing Peng, Ping Lu, Kaizhi Zheng, Siobhan M. Craige, Lawrence M. Lifshitz, John F. Keaney Jr, Kevin E. Fogarty, Ronghua ZhuGe, Min-Sheng Zhu
Nat Commun. 2016; 7: 11358. Published online 2016 Apr 22. doi: 10.1038/ncomms11358
PMCID:
PMC4844698
ArticlePDF–1.0M
15.
TRA2β controls Mypt1 exon 24 splicing in the developmental maturation of mouse mesenteric artery smooth muscle
Xiaoxu Zheng, John J. Reho, Brunhilde Wirth, Steven A. Fisher
Am J Physiol Cell Physiol. 2015 Feb 15; 308(4): C289–C296. Published online 2014 Nov 26. doi: 10.1152/ajpcell.00304.2014
PMCID:
PMC4329427
Article
16.
Tra2β Protein Is Required for Tissue-specific Splicing of a Smooth Muscle Myosin Phosphatase Targeting Subunit Alternative Exon
Kang Fu, Ylva Mende, Bhupal P. Bhetwal, Salah Baker, Brian A. Perrino, Brunhilde Wirth, Steven A. Fisher
J Biol Chem. 2012 May 11; 287(20): 16575–16585. Published online 2012 Mar 21. doi: 10.1074/jbc.M111.325761
PMCID:
PMC3351297
ArticlePDF–2.2M
17.
Regulation of basal LC20 phosphorylation by MYPT1 and CPI-17 in murine gastric antrum, gastric fundus, and proximal colon smooth muscles
Bhupal P. Bhetwal, Chang Long An, Steven A. Fisher, Brian A. Perrino
Neurogastroenterol Motil. Author manuscript; available in PMC 2012 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2011 Oct; 23(10): e425–e436. Published online 2011 Aug 24. doi: 10.1111/j.1365-2982.2011.01769.x
PMCID:
PMC3173524
ArticlePDF–1.8M
18.
Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model
Yan Wang, Ting-Ting Gao, Dun-Feng Xu, Xiao-Yan Zhu, Wen-Wen Dong, Zhou Lv, Yu-Jian Liu, Lai Jiang
Int J Mol Med. 2019 Dec; 44(6): 2077–2090. Published online 2019 Oct 21. doi: 10.3892/ijmm.2019.4379
PMCID:
PMC6844625
ArticlePDF–1.1M
19.
Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis
John J. Reho, Xiaoxu Zheng, Laureano D. Asico, Steven A. Fisher
Am J Physiol Heart Circ Physiol. 2015 May 1; 308(9): H1039–H1050. Published online 2015 Feb 27. doi: 10.1152/ajpheart.00912.2014
PMCID:
PMC4551119
Article
20.
Tra2β as a novel mediator of vascular smooth muscle diversification
Supriya Shukla, Steven A. Fisher
Circ Res. Author manuscript; available in PMC 2009 Sep 3.
Published in final edited form as: Circ Res. 2008 Aug 29; 103(5): 485–492. Published online 2008 Jul 31. doi: 10.1161/CIRCRESAHA.108.178384
PMCID:
PMC2737447
ArticlePDF–1.8M

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