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Select item 110039351.

MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination

Xiaohong Dong, Zhi Zhang, Xin Shu, Zi Zhuang, Pinyi Liu, Renyuan Liu, Shengnan Xia, Xinyu Bao, Yun Xu, Yan Chen

Neurosci Bull. 2024 Apr; 40(4): 483–499. Published online 2023 Nov 18. doi: 10.1007/s12264-023-01147-1

PMCID:: PMC11003935

Article PDF–17M

Select item 92368482.

MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice

Jun Hu, Hui Du, Yinglin Yuan, Peipei Guo, Junxia Yang, Xinru Yin, Jin Liu, Shengwang Wu, Jingyuan Wan, Xia Gong

Mediators Inflamm. 2022; 2022: 5791915. Published online 2022 Jun 20. doi: 10.1155/2022/5791915

PMCID:: PMC9236848

Article PDF–2.5M

Select item 90273783.

MFG-E8 Reduces Aortic Intimal Proliferation in a Murine Model of Transplant Vasculopathy

Benoit Brilland, Patrick Laplante, Pamela Thebault, Karen Geoffroy, Marie-Joëlle Brissette, Mathieu Latour, Michaël Chassé, Shijie Qi, Marie-Josée Hébert, Héloïse Cardinal, Jean-François Cailhier

Int J Mol Sci. 2022 Apr; 23(8): 4094. Published online 2022 Apr 7. doi: 10.3390/ijms23084094

PMCID:: PMC9027378

Article PDF–1.7M

Select item 90186964.

MFG-E8 promotes osteogenic transdifferentiation of smooth muscle cells and vascular calcification by regulating TGF-β1 signaling

Hou-Yu Chiang, Pao-Hsien Chu, Shao-Chi Chen, Ting-Hein Lee

Commun Biol. 2022; 5: 364. Published online 2022 Apr 19. doi: 10.1038/s42003-022-03313-z

PMCID:: PMC9018696

Article PDF–12M

Select item 88391695.

Protective Effect of MFG-E8 on Necroptosis-Induced Intestinal Inflammation and Enteroendocrine Cell Function in Diabetes

Xiaomin Hua, Baoying Li, Fei Yu, Wenqian Zhao, Yuwei Tan, Xiaoli Li, Chunli Fu, Xin Yu, Haiqing Gao, Mei Cheng

Nutrients. 2022 Feb; 14(3): 604. Published online 2022 Jan 29. doi: 10.3390/nu14030604

PMCID:: PMC8839169

Article PDF–6.2M

Select item 87958346.

MFG-E8 Maintains Cellular Homeostasis by Suppressing Endoplasmic Reticulum Stress in Pancreatic Exocrine Acinar Cells

Yifan Ren, Wuming Liu, Jia Zhang, Jianbin Bi, Meng Fan, Yi Lv, Zheng Wu, Yuanyuan Zhang, Rongqian Wu

Front Cell Dev Biol. 2021; 9: 803876. Published online 2022 Jan 14. doi: 10.3389/fcell.2021.803876

Correction in:: Front Cell Dev Biol. 2022; 10: 1121052.

PMCID:: PMC8795834

Article PDF–5.7M

Select item 87610107.

Increased MFG‐E8 at neuromuscular junctions is an exacerbating factor for sarcopenia‐associated denervation

Madoka Ikemoto‐Uezumi, Heying Zhou, Tamaki Kurosawa, Yuki Yoshimoto, Masashi Toyoda, Nobuo Kanazawa, Tatsu Nakazawa, Mitsuhiro Morita, Kunihiro Tsuchida, Akiyoshi Uezumi

Aging Cell. 2022 Jan; 21(1): e13536. Published online 2021 Dec 24. doi: 10.1111/acel.13536

PMCID:: PMC8761010

Article PDF–1.8M

Select item 85957938.

Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart

Mallikarjun Patil, Sherin Saheera, Praveen K Dubey, Asher Kahn-Krell, Prem Kumar Govindappa, Sarojini Singh, Sultan Tousif, Qinkun Zhang, Hind Lal, Jianyi Zhang, Gangjian Qin, Prasanna Krishnamurthy

Circ Res. Author manuscript; available in PMC 2022 Nov 12.

Published in final edited form as: Circ Res. 2021 Nov 12; 129(11): 1006–1020. Published online 2021 Oct 8. doi: 10.1161/CIRCRESAHA.120.317900

PMCID:: PMC8595793

Article PDF–1.7M

Select item 84835109.

MFG‐E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose‐Dependent Mediation of Actin Polymerization

Hou‐Yu Chiang, Pao‐Hsien Chu, Shao‐Chi Chen, Ting‐Hein Lee

J Am Heart Assoc. 2021 Jun 1; 10(11): e020870. Published online 2021 May 27. doi: 10.1161/JAHA.121.020870

PMCID:: PMC8483510

Article PDF–5.5M

Select item 844449810.

MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy

Paula Marazuela, Montse Solé, Anna Bonaterra-Pastra, Jesús Pizarro, Jessica Camacho, Elena Martínez-Sáez, H. Bea Kuiperij, Marcel M. Verbeek, Anna M. de Kort, Floris H. B. M. Schreuder, Catharina J. M. Klijn, Laura Castillo-Ribelles, Olalla Pancorbo, David Rodríguez-Luna, Francesc Pujadas, Pilar Delgado, Mar Hernández-Guillamon

Acta Neuropathol Commun. 2021; 9: 154. Published online 2021 Sep 16. doi: 10.1186/s40478-021-01257-9

PMCID:: PMC8444498

Article PDF–7.3M

Select item 806446711.

MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice

Heng-Fu Bu, Saravanan Subramanian, Hua Geng, Xiao Wang, Fangyi Liu, Pauline M. Chou, Chao Du, Isabelle G. De Plaen, Xiao-Di Tan

Cells. 2021 Apr; 10(4): 728. Published online 2021 Mar 25. doi: 10.3390/cells10040728

PMCID:: PMC8064467

Article PDF–25M

Select item 779655312.

Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8

Xiaoying Cai, Ying Li, Xiaoyang Zheng, Rong Hu, Yingyuan Li, Liangcan Xiao, Zhongxing Wang

J Neuroinflammation. 2021; 18: 18. Published online 2021 Jan 9. doi: 10.1186/s12974-020-02061-3

PMCID:: PMC7796553

Article PDF–2.9M

Select item 671688013.

MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells

Hou-Yu Chiang, Pao-Hsien Chu, Ting-Hein Lee

J Biomed Sci. 2019; 26: 61. Published online 2019 Aug 30. doi: 10.1186/s12929-019-0559-0

PMCID:: PMC6716880

Article PDF–9.4M

Select item 643636014.

Milk Fat Globule-Epidermal Growth Factor-Factor 8 Reverses Lipopolysaccharide-Induced Microglial Oxidative Stress

Jie Li, Xiaotian Xu, Xiaoying Cai, Yinlun Weng, Yiping Wang, Qingyu Shen, Xiaolei Shi

Oxid Med Cell Longev. 2019; 2019: 2601394. Published online 2019 Mar 13. doi: 10.1155/2019/2601394

PMCID:: PMC6436360

Article PDF–3.3M

Select item 616132015.

Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

Jack Brelstaff, Aviva M. Tolkovsky, Bernardino Ghetti, Michel Goedert, Maria Grazia Spillantini

Cell Rep. Author manuscript; available in PMC 2018 Sep 28.

Published in final edited form as: Cell Rep. 2018 Aug 21; 24(8): 1939–1948.e4. doi: 10.1016/j.celrep.2018.07.072

PMCID:: PMC6161320

Article PDF–1.2M

Select item 612876716.

Autocrine Mfge8 signaling prevents developmental exhaustion of the adult neural stem cell pool

Yi Zhou, Allison M. Bond, Jamie E. Shade, Yunhua Zhu, Chung-ha O. Davis, Xinyuan Wang, Yijing Su, Ki-Jun Yoon, Alexander T. Phan, William J. Chen, Justin H. Oh, Nicholas Marsh-Armstrong, Kamran Atabai, Guo-li Ming, Hongjun Song

Cell Stem Cell. Author manuscript; available in PMC 2019 Sep 6.

Published in final edited form as: Cell Stem Cell. 2018 Sep 6; 23(3): 444–452.e4. Published online 2018 Aug 30. doi: 10.1016/j.stem.2018.08.005

PMCID:: PMC6128767

Article PDF–1.6M

Select item 579450217.

Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice

Yuan Zhou, Wei Cai, Zilong Zhao, Tristan Hilton, Min Wang, Jason Yeon, Wei Liu, Fangyi Zhang, Fu-Dong Shi, Xiaoping Wu, Perumal Thiagarajan, Min Li, Jianning Zhang, Jing-fei Dong

Blood. 2018 Feb 1; 131(5): 563–572. Prepublished online 2017 Nov 21. doi: 10.1182/blood-2017-08-801738

PMCID:: PMC5794502

Article

Select item 529970818.

Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage

Wei Huang, Jiyuan Wu, Huiqin Yang, Yin Xiong, Rui Jiang, Tianpen Cui, Duyun Ye

Cell Death Differ. 2017 Feb; 24(2): 263–275. Published online 2016 Oct 21. doi: 10.1038/cdd.2016.115

PMCID:: PMC5299708

Article PDF–5.1M

Select item 519969619.

Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction

Michio Nakaya, Kenji Watari, Mitsuru Tajima, Takeo Nakaya, Shoichi Matsuda, Hiroki Ohara, Hiroaki Nishihara, Hiroshi Yamaguchi, Akiko Hashimoto, Mitsuho Nishida, Akiomi Nagasaka, Yuma Horii, Hiroki Ono, Gentaro Iribe, Ryuji Inoue, Makoto Tsuda, Kazuhide Inoue, Akira Tanaka, Masahiko Kuroda, Shigekazu Nagata, Hitoshi Kurose

J Clin Invest. 2017 Jan 3; 127(1): 383–401. Published online 2016 Dec 5. doi: 10.1172/JCI83822

PMCID:: PMC5199696

Article PDF–4.8M

Select item 509017420.

Correction of MFG-E8 resolves inflammation and promotes cutaneous wound healing in diabetes

Amitava Das, Subhadip Ghatak, Mithun Sinha, Scott Chaffee, Noha S. Ahmed, Narasimham L. Parinandi, Eric S. Wohleb, John F. Sheridan, Chandan K. Sen, Sashwati Roy

J Immunol. Author manuscript; available in PMC 2017 Jun 15.

Published in final edited form as: J Immunol. 2016 Jun 15; 196(12): 5089–5100. Published online 2016 May 18. doi: 10.4049/jimmunol.1502270