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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
Meprin β expression modulates the interleukin‐6 mediated JAK2‐STAT3 signaling pathway in ischemia/reperfusion‐induced kidney injury
Shaymaa Abousaad, Faihaa Ahmed, Ayman Abouzeid, Elimelda Moige Ongeri
Physiol Rep. 2022 Sep; 10(18): e15468. Published online 2022 Sep 18. doi: 10.14814/phy2.15468
PMCID:
PMC9483619
ArticlePDF–29M
3.
LC-MS-based metabolomics analysis to identify meprin-β-associated changes in kidney tissue from mice with STZ-induced type 1 diabetes and diabetic kidney injury
Jessica Gooding, Lei Cao, Faihaa Ahmed, Jean-Marie Mwiza, Mizpha Fernander, Courtney Whitaker, Zach Acuff, Susan McRitchie, Susan Sumner, Elimelda Moige Ongeri
Am J Physiol Renal Physiol. 2019 Oct 1; 317(4): F1034–F1046. Published online 2019 Aug 14. doi: 10.1152/ajprenal.00166.2019
PMCID:
PMC6843037
Article
4.
Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes
John E. Bylander, Faihaa Ahmed, Sabena M. Conley, Jean-Marie Mwiza, Elimelda Moige Ongeri
J Diabetes Res. 2017; 2017: 9035038. Published online 2017 Jul 19. doi: 10.1155/2017/9035038
Correction in:
J Diabetes Res. 2018; 2018: 2462697.
PMCID:
PMC5540529
ArticlePDF–3.1M
5.
Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site
Caroline Schönherr, Jessica Bien, Simone Isbert, Rielana Wichert, Johannes Prox, Hermann Altmeppen, Sathish Kumar, Jochen Walter, Stefan F. Lichtenthaler, Sascha Weggen, Markus Glatzel, Christoph Becker-Pauly, Claus U. Pietrzik
Mol Neurodegener. 2016; 11: 19. Published online 2016 Feb 19. doi: 10.1186/s13024-016-0084-5
PMCID:
PMC4759862
ArticlePDF–1.7M
6.
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer’s disease
Liana Marengo, Fred Armbrust, Caroline Schoenherr, Steffen E. Storck, Ulrich Schmitt, Silvia Zampar, Oliver Wirths, Hermann Altmeppen, Markus Glatzel, Christoph Kaether, Sascha Weggen, Christoph Becker-Pauly, Claus U. Pietrzik
Cell Mol Life Sci. 2022; 79(3): 168. Published online 2022 Mar 2. doi: 10.1007/s00018-022-04205-5
PMCID:
PMC8891209
ArticlePDF–2.4M
7.
Meprin-β activity modulates the β-catalytic subunit of protein kinase A in ischemia-reperfusion-induced acute kidney injury
Faihaa Ahmed, Jean-Marie Mwiza, Mizpha Fernander, Ismaila Yahaya, Shaymaa Abousaad, Elimelda Moige Ongeri
Am J Physiol Renal Physiol. 2020 May 1; 318(5): F1147–F1159. Published online 2020 Mar 16. doi: 10.1152/ajprenal.00571.2019
PMCID:
PMC7294336
Article
8.
Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes
Florian Peters, Franka Scharfenberg, Cynthia Colmorgen, Fred Armbrust, Rielana Wichert, Philipp Arnold, Barbara Potempa, Jan Potempa, Claus U. Pietrzik, Robert Häsler, Philip Rosenstiel, Christoph Becker-Pauly
FASEB J. 2019 Jun; 33(6): 7490–7504. Published online 2019 Mar 27. doi: 10.1096/fj.201802391R
PMCID:
PMC6529335
Article
9.
Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicity
Christian Herzog, Raju Marisiddaiah, Randy S. Haun, Gur P. Kaushal
Toxicol Lett. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Toxicol Lett. 2015 Jul 16; 236(2): 110–116. Published online 2015 May 6. doi: 10.1016/j.toxlet.2015.05.005
PMCID:
PMC4457671
ArticlePDF–2.1M
10.
Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: significance in acute and chronic kidney injury
Jean-Marie V. Niyitegeka, Adam C. Bastidas, Robert H. Newman, Susan S. Taylor, Elimelda Moige Ongeri
Am J Physiol Renal Physiol. 2015 Jan 1; 308(1): F56–F68. Published online 2014 Oct 29. doi: 10.1152/ajprenal.00167.2014
PMCID:
PMC4281694
Article
11.
Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength
Claudia Broder, Philipp Arnold, Sandrine Vadon-Le Goff, Moritz A. Konerding, Kerstin Bahr, Stefan Müller, Christopher M. Overall, Judith S. Bond, Tomas Koudelka, Andreas Tholey, David J. S. Hulmes, Catherine Moali, Christoph Becker-Pauly
Proc Natl Acad Sci U S A. 2013 Aug 27; 110(35): 14219–14224. Published online 2013 Aug 12. doi: 10.1073/pnas.1305464110
PMCID:
PMC3761563
ArticlePDF–954K
12.
Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragments in Vivo
Tamara Jefferson, Mirsada Čaušević, Ulrich auf dem Keller, Oliver Schilling, Simone Isbert, Rebecca Geyer, Wladislaw Maier, Sabrina Tschickardt, Thorsten Jumpertz, Sascha Weggen, Judith S. Bond, Christopher M. Overall, Claus U. Pietrzik, Christoph Becker-Pauly
J Biol Chem. 2011 Aug 5; 286(31): 27741–27750. Published online 2011 Jun 6. doi: 10.1074/jbc.M111.252718
PMCID:
PMC3149364
ArticlePDF–1.6M
13.
Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease
Sanjita Banerjee, Ge Jin, S. Gaylen Bradley, Gail L. Matters, Ryan D. Gailey, Jacqueline M. Crisman, Judith S. Bond
Am J Physiol Gastrointest Liver Physiol. 2011 Feb; 300(2): G273–G282. Published online 2010 Nov 11. doi: 10.1152/ajpgi.00504.2009
PMCID:
PMC3043644
Article
14.
Disruption of the Meprin Alpha and Beta Genes in Mice Alters Homeostasis of Monocytes and Natural Killer Cells
Qi Sun, Hong-Jian Jin, Judith S. Bond
Exp Hematol. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Exp Hematol. 2009 Mar; 37(3): 346–356. Published online 2008 Dec 24. doi: 10.1016/j.exphem.2008.10.016
PMCID:
PMC2674388
ArticlePDF–1.0M
15.
Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge
Renee E. Yura, S. Gaylen Bradley, Ganesan Ramesh, W. Brian Reeves, Judith S. Bond
Am J Physiol Renal Physiol. 2009 Jan; 296(1): F135–F144. Published online 2008 Oct 29. doi: 10.1152/ajprenal.90524.2008
PMCID:
PMC2636909
Article
16.
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis
Cynthia Bülck, Elisabeth E. L. Nyström, Tomas Koudelka, Michael Mannbar-Frahm, Gerrit Andresen, Mariem Radhouani, Florian Tran, Franka Scharfenberg, Friederike Schrell, Fred Armbrust, Eileen Dahlke, Bei Zhao, Alex Vervaeke, Franziska Theilig, Philip Rosenstiel, Philipp Starkl, Stephan P. Rosshart, Helmut Fickenscher, Andreas Tholey, Gunnar C. Hansson, Christoph Becker-Pauly
Sci Adv. 2023 Mar; 9(13): eadf4055. Published online 2023 Mar 31. doi: 10.1126/sciadv.adf4055
PMCID:
PMC10065446
ArticlePDF–2.7M
17.
Meprin β contributes to collagen deposition in lung fibrosis
V. Biasin, M. Wygrecka, L. M. Marsh, C. Becker-Pauly, L. Brcic, B. Ghanim, W. Klepetko, A. Olschewski, G. Kwapiszewska
Sci Rep. 2017; 7: 39969. Published online 2017 Jan 6. doi: 10.1038/srep39969
PMCID:
PMC5216360
ArticlePDF–3.3M
18.
Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus
André Schütte, Anna Ermund, Christoph Becker-Pauly, Malin E. V. Johansson, Ana M. Rodriguez-Pineiro, Fredrik Bäckhed, Stefan Müller, Daniel Lottaz, Judith S. Bond, Gunnar C. Hansson
Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34): 12396–12401. Published online 2014 Aug 11. doi: 10.1073/pnas.1407597111
PMCID:
PMC4151749
ArticlePDF–1.3M
19.
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
Tamara Jefferson, Ulrich auf dem Keller, Caroline Bellac, Verena V. Metz, Claudia Broder, Jana Hedrich, Anke Ohler, Wladislaw Maier, Viktor Magdolen, Erwin Sterchi, Judith S. Bond, Arumugam Jayakumar, Heiko Traupe, Athena Chalaris, Stefan Rose-John, Claus U. Pietrzik, Rolf Postina, Christopher M. Overall, Christoph Becker-Pauly
Cell Mol Life Sci. 2013; 70(2): 309–333. Published online 2012 Sep 1. doi: 10.1007/s00018-012-1106-2
PMCID:
PMC3535375
ArticlePDF–3.6M
20.
Villin and actin in the mouse kidney brush-border membrane bind to and are degraded by meprins, an interaction that contributes to injury in ischemia-reperfusion
Elimelda Moige Ongeri, Odinaka Anyanwu, W. Brian Reeves, Judith S. Bond
Am J Physiol Renal Physiol. 2011 Oct; 301(4): F871–F882. Published online 2011 Jul 27. doi: 10.1152/ajprenal.00703.2010
PMCID:
PMC3191804
Article

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