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Select item 92560791.

MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF-κB pathway

Jiecheng Ye, Wanying Deng, Ying Zhong, Hui Liu, Baoyin Guo, Zixi Qin, Peiwen Li, Xueyun Zhong, Lihui Wang

Int J Oncol. 2022 Aug; 61(2): 94. Published online 2022 Jun 21. doi: 10.3892/ijo.2022.5384

PMCID:: PMC9256079

Article PDF–2.4M

Select item 65225032.

Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice

Hyun-A. Seong, Hyunjung Ha

Cell Death Dis. 2019 Jun; 10(6): 380. Published online 2019 May 16. doi: 10.1038/s41419-019-1616-z

PMCID:: PMC6522503

Article PDF–2.6M

Select item 59201103.

Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activity

Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Cell Death Dis. 2018 May; 9(5): 471. Published online 2018 Apr 27. doi: 10.1038/s41419-018-0489-x

PMCID:: PMC5920110

Article PDF–2.6M

Select item 42702404.

Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β‐cell, regeneration

Cheng‐Ho Chung, Amber Miller, Andreas Panopoulos, Ergeng Hao, Robert Margolis, Alexey Terskikh, Fred Levine

Physiol Rep. 2014 Sep; 2(9): e12131. Published online 2014 Sep 4. doi: 10.14814/phy2.12131

PMCID:: PMC4270240

Article PDF–3.6M

Select item 39902645.

MELK is Upregulated and Required in Mammary Tumor Initiating Cells In Vivo

Lionel Hebbard, Jochen Maurer, Amber Miller, Jacqueline Lesperance, John Hassell, Robert G. Oshima, Alexey Terskikh

Cancer Res. Author manuscript; available in PMC 2014 Apr 17.

Published in final edited form as: Cancer Res. 2010 Nov 1; 70(21): 8863–8873. Published online 2010 Sep 22. doi: 10.1158/0008-5472.CAN-10-1295

PMCID:: PMC3990264

Article PDF–1.7M

Select item 39402016.

The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity

Yong-Soon Cho, Jiho Yoo, Soomin Park, Hyun-Soo Cho

Acta Crystallogr D Biol Crystallogr. 2014 Feb 1; 70(Pt 2): 514–521. Published online 2014 Jan 31. doi: 10.1107/S1399004713027806

PMCID:: PMC3940201

Article PDF–1.2M

Select item 40593817.

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

Yubao Wang, Young-Mi Lee, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao

eLife. 2014; 3: e01763. Published online 2014 May 20. doi: 10.7554/eLife.01763

Correction in:: eLife. 2018; 7: e36414.

PMCID:: PMC4059381

Article PDF–4.0M

Select item 33755058.

PDK1 Protein Phosphorylation at Thr³⁵⁴ by Murine Protein Serine-Threonine Kinase 38 Contributes to Negative Regulation of PDK1 Protein Activity

Hyun-A Seong, Haiyoung Jung, Ravi Manoharan, Hyunjung Ha

J Biol Chem. 2012 Jun 15; 287(25): 20811–20822. Published online 2012 Apr 27. doi: 10.1074/jbc.M111.331827

PMCID:: PMC3375505

Article PDF–2.3M

Select item 33755049.

Murine Protein Serine-threonine Kinase 38 Activates p53 Function through Ser¹⁵ Phosphorylation

Hyun-A Seong, Hyunjung Ha

J Biol Chem. 2012 Jun 15; 287(25): 20797–20810. Published online 2012 Apr 24. doi: 10.1074/jbc.M112.347757

PMCID:: PMC3375504

Article PDF–2.9M

Select item 294558710.

Murine Protein Serine/Threonine Kinase 38 Stimulates TGF-β Signaling in a Kinase-dependent Manner via Direct Phosphorylation of Smad Proteins

Hyun-A Seong, Haiyoung Jung, Hyunjung Ha

J Biol Chem. 2010 Oct 1; 285(40): 30959–30970. Published online 2010 Jul 21. doi: 10.1074/jbc.M110.138370

PMCID:: PMC2945587

Article PDF–2.8M

Select item 122234211.

Phosphorylation of a novel zinc-finger-like protein, ZPR9, by murine protein serine/threonine kinase 38 (MPK38).

Hyun-A Seong, Minchan Gil, Kyong-Tai Kim, Sung-Jin Kim, Hyunjung Ha

Biochem J. 2002 Feb 1; 361(Pt 3): 597–604. doi: 10.1042/0264-6021:3610597

PMCID:: PMC1222342

Summary PDF–274K

Select item 411317912.

Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

Tao Du, Ying Qu, Jianfang Li, Hao Li, Liping Su, Quan Zhou, Min Yan, Chen Li, Zhenggang Zhu, Bingya Liu

Mol Cancer. 2014; 13: 100. Published online 2014 May 4. doi: 10.1186/1476-4598-13-100

PMCID:: PMC4113179

Article PDF–2.3M

Select item 325989413.

Murine Protein Serine/Threonine Kinase 38 Activates Apoptosis Signal-regulating Kinase 1 via Thr⁸³⁸ Phosphorylation

Haiyoung Jung, Hyun-A Seong, Hyunjung Ha

J Biol Chem. 2008 Dec 12; 283(50): 34541–34553. doi: 10.1074/jbc.M807219200

PMCID:: PMC3259894

Article PDF–1.0M

Select item 217147514.

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

Ichiro Nakano, Andres A. Paucar, Ruchi Bajpai, Joseph D. Dougherty, Amani Zewail, Theresa K. Kelly, Kevin J. Kim, Jing Ou, Matthias Groszer, Tetsuya Imura, William A. Freije, Stanley F. Nelson, Michael V. Sofroniew, Hong Wu, Xin Liu, Alexey V. Terskikh, Daniel H. Geschwind, Harley I. Kornblum

J Cell Biol. 2005 Aug 1; 170(3): 413–427. doi: 10.1083/jcb.200412115

PMCID:: PMC2171475

Article PDF–3.5M

Select item 391664915.

Novel Protein Interactions with Endoglin and Activin Receptor-like Kinase 1: Potential Role in Vascular Networks

Guoxiong Xu, Miriam Barrios-Rodiles, Mirjana Jerkic, Andrei L. Turinsky, Robert Nadon, Sonia Vera, Despina Voulgaraki, Jeffrey L. Wrana, Mourad Toporsian, Michelle Letarte

Mol Cell Proteomics. 2014 Feb; 13(2): 489–502. Published online 2013 Dec 7. doi: 10.1074/mcp.M113.033464

PMCID:: PMC3916649

Article PDF–4.1M

Select item 645951016.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Article PDF–5.1M

Select item 741599117.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Article PDF–2.0M

Select item 30876318.

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller, Gregor Eichele

Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029

PMCID:: PMC308763

Article PDF–253K

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 793877020.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

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