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Select item 61890461.

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae

Shilpi Chandra, James Gray, William B. Kiosses, Archana Khurana, Kaori Hitomi, Catherine M. Crosby, Ashu Chawla, Zheng Fu, Meng Zhao, Natacha Veerapen, Stewart K. Richardson, Steven A. Porcelli, Gurdyal Besra, Amy R. Howell, Sonia Sharma, Bjoern Peters, Mitchell Kronenberg

Nat Commun. 2018; 9: 4279. Published online 2018 Oct 15. doi: 10.1038/s41467-018-06646-8

PMCID:: PMC6189046

Article PDF–7.3M

Select item 49147932.

Loss of Mrp1 Potentiates Doxorubicin-Induced Cytotoxicity in Neonatal Mouse Cardiomyocytes and Cardiac Fibroblasts

Wei Zhang, Daret St Clair, Allan Butterfield, Mary Vore

Toxicol Sci. 2016 May; 151(1): 44–56. Published online 2016 Jan 27. doi: 10.1093/toxsci/kfw021

PMCID:: PMC4914793

Article PDF–762K

Select item 48589623.

Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells

Gayle M. Gordillo, Ayan Biswas, Savita Khanna, James M. Spieldenner, Xueliang Pan, Chandan K. Sen

J Biol Chem. 2016 May 6; 291(19): 10089–10103. Published online 2016 Mar 9. doi: 10.1074/jbc.M115.688879

Correction in:: J Biol Chem. 2016 Jul 1; 291(27): 14394.

PMCID:: PMC4858962

Article PDF–3.4M

Select item 40511554.

Lipopolysaccharide Increases the Expression of Multidrug Resistance-Associated Protein 1 (ABCC1) in Macrophages

Peter S. Silverstein, Kenneth L. Audus, Nilofer Qureshi, Anil Kumar

J Neuroimmune Pharmacol. Author manuscript; available in PMC 2014 Jun 10.

Published in final edited form as: J Neuroimmune Pharmacol. 2010 Dec; 5(4): 516–520. Published online 2009 Nov 6. doi: 10.1007/s11481-009-9180-4

PMCID:: PMC4051155

Article PDF–652K

Select item 28628345.

Mice lacking Mrp1 have reduced testicular steroid hormone levels and alterations in steroid biosynthetic enzymes

JEFFREY C. SIVILS, IVEN GONZALEZ, LISA J. BAIN

Gen Comp Endocrinol. Author manuscript; available in PMC 2011 May 15.

Published in final edited form as: Gen Comp Endocrinol. 2010 May 15; 167(1): 51–59. Published online 2010 Feb 21. doi: 10.1016/j.ygcen.2010.02.019

PMCID:: PMC2862834

Article PDF–990K

Select item 22133896.

Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage

Jan Wijnholds, George L. Scheffer, Martin van der Valk, Paul van der Valk, Jos H. Beijnen, Rik J. Scheper, Piet Borst

J Exp Med. 1998 Sep 7; 188(5): 797–808. doi: 10.1084/jem.188.5.797

PMCID:: PMC2213389

Article PDF–716K

Select item 60340767.

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick

mSphere. 2018 Jul-Aug; 3(4): e00303-18. Published online 2018 Jul 5. doi: 10.1128/mSphere.00303-18

PMCID:: PMC6034076

Article PDF–1.0M

Select item 47152598.

Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1)

Ronald G. Udasin, Xia Wen, Kristin M. Bircsak, Lauren M. Aleksunes, Michael P. Shakarjian, Ah-Ng Tony Kong, Diane E. Heck, Debra L. Laskin, Jeffrey D. Laskin

Toxicol Sci. 2016 Jan; 149(1): 202–212. Published online 2015 Oct 9. doi: 10.1093/toxsci/kfv226

PMCID:: PMC4715259

Article PDF–571K

Select item 37290449.

Loss of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner

Jeffrey C. Sivils, Tiffany M. Ancrum, Lisa J. Bain

J Appl Toxicol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: J Appl Toxicol. 2013 Aug; 33(8): 766–773. Published online 2012 Apr 23. doi: 10.1002/jat.2727

PMCID:: PMC3729044

Article PDF–1.4M

Select item 358780810.

Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood–brain and blood–spinal cord barriers

Tara A Cartwright, Christopher R Campos, Ronald E Cannon, David S Miller

J Cereb Blood Flow Metab. 2013 Mar; 33(3): 381–388. Published online 2012 Nov 21. doi: 10.1038/jcbfm.2012.174

PMCID:: PMC3587808

Article PDF–561K

Select item 355484111.

Metallothionein blocks oxidative DNA damage in vitro

Wei Qu, Jingbo Pi, Michael P. Waalkes

Arch Toxicol. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Arch Toxicol. 2013 Feb; 87(2): 311–321. Published online 2012 Aug 23. doi: 10.1007/s00204-012-0927-y

PMCID:: PMC3554841

Article PDF–1.9M

Select item 190648412.

Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis

A VERBON, J C LEEMANS, S WEIJER, S FLORQUIN, T VAN DER POLL

Clin Exp Immunol. 2002 Oct; 130(1): 32–36. doi: 10.1046/j.1365-2249.2002.01952.x

PMCID:: PMC1906484

Article PDF–511K

Select item 178017913.

Interferon-γ Plays Protective Roles in Sodium Arsenite-Induced Renal Injury by Up-Regulating Intrarenal Multidrug Resistance-Associated Protein 1 Expression

Akihiko Kimura, Yuko Ishida, Takahito Hayashi, Takashi Wada, Hitoshi Yokoyama, Takeshi Sugaya, Naofumi Mukaida, Toshikazu Kondo

Am J Pathol. 2006 Oct; 169(4): 1118–1128. doi: 10.2353/ajpath.2006.060024

PMCID:: PMC1780179

Article PDF–3.2M

Select item 412566514.

Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice

Bao-Jin Zhai, Ze-Yong Shao, Chun-Liang Zhao, Kai Hu, Feng Wu

World J Gastroenterol. 2006 Nov 7; 12(41): 6614–6619. Published online 2006 Nov 7. doi: 10.3748/wjg.v12.i41.6614

PMCID:: PMC4125665

Article PDF–881K

Select item 330773415.

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

Parameswaran G. Sreekumar, Christine Spee, Stephen J. Ryan, Susan P. C. Cole, Ram Kannan, David R. Hinton

PLoS One. 2012; 7(3): e33420. Published online 2012 Mar 19. doi: 10.1371/journal.pone.0033420

PMCID:: PMC3307734

Article PDF–1013K

Select item 324911516.

Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes

Hiu Chuen Lok, Yohan Suryo Rahmanto, Clare L. Hawkins, Danuta S. Kalinowski, Charles S. Morrow, Alan J. Townsend, Prem Ponka, Des R. Richardson

J Biol Chem. 2012 Jan 2; 287(1): 607–618. Published online 2011 Nov 14. doi: 10.1074/jbc.M111.310987

PMCID:: PMC3249115

Article PDF–4.7M

Select item 195050517.

Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice

Margaretha van der Deen, Wim Timens, Hetty Timmer-Bosscha, Barry W van der Strate, Rik J Scheper, Dirkje S Postma, Elisabeth G de Vries, Huib A Kerstjens

Respir Res. 2007; 8(1): 49. Published online 2007 Jul 7. doi: 10.1186/1465-9921-8-49

PMCID:: PMC1950505

Article PDF–759K

Select item 109178018.

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

Noam Zelcer, Koen van de Wetering, Michel Hillebrand, Elise Sarton, Annemieke Kuil, Peter R. Wielinga, Thomas Tephly, Albert Dahan, Jos H. Beijnen, Piet Borst

Proc Natl Acad Sci U S A. 2005 May 17; 102(20): 7274–7279. Published online 2005 May 10. doi: 10.1073/pnas.0502530102

PMCID:: PMC1091780

Article PDF–415K

Select item 37744719.

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

Jan Wijnholds, Elizabeth C.M. de Lange, George L. Scheffer, Dirk-Jan van den Berg, Carla A.A.M. Mol, Martin van der Valk, Alfred H. Schinkel, Rik J. Scheper, Douwe D. Breimer, Piet Borst

J Clin Invest. 2000 Feb 1; 105(3): 279–285. doi: 10.1172/JCI8267