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Select item 46409771.

An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease

Patricia Tagliaferro, Tatyana Kareva, Tinmarla F Oo, Olga Yarygina, Nikolai Kholodilov, Robert E Burke

Neurobiol Dis. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Neurobiol Dis. 2015 Oct; 82: 359–371. Published online 2015 Jul 17. doi: 10.1016/j.nbd.2015.07.009

PMCID:: PMC4640977

Article PDF–2.3M

Select item 42536472.

A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2^R1441G) transgenic mouse model of Parkinson’s disease

Brian P. Dranka, Alison Gifford, Donna McAllister, Jacek Zielonka, Joy Joseph, Crystal L. O’Hara, Cheryl L. Stucky, Anumantha G. Kanthasamy, Balaraman Kalyanaraman

Neurosci Lett. Author manuscript; available in PMC 2015 Nov 7.

Published in final edited form as: Neurosci Lett. 2014 Nov 7; 583: 159–164. Published online 2014 Sep 26. doi: 10.1016/j.neulet.2014.09.042

PMCID:: PMC4253647

Article PDF–661K

Select item 37298853.

Diapocynin prevents early Parkinson’s disease symptoms in the Leucine-Rich Repeat Kinase 2 (LRRK2^R1441G) transgenic mouse

Brian P. Dranka, Alison Gifford, Anamitra Ghosh, Jacek Zielonka, Joy Joseph, Anumantha G. Kanthasamy, Balaraman Kalyanaraman

Neurosci Lett. Author manuscript; available in PMC 2014 Aug 9.

Published in final edited form as: Neurosci Lett. 2013 Aug 9; 549: 57–62. Published online 2013 May 28. doi: 10.1016/j.neulet.2013.05.034

PMCID:: PMC3729885

Article PDF–1.5M

Select item 28459304.

Mutant LRRK2^R1441G BAC transgenic mice recapitulate cardinal features of Parkinson’s disease

Yanping Li, Wencheng Liu, Tinmarla F Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Mikhail Bogdanov, Serge Przedborski, M Flint Beal, Robert E Burke, Chenjian Li

Nat Neurosci. Author manuscript; available in PMC 2010 Mar 26.

Published in final edited form as: Nat Neurosci. 2009 Jul; 12(7): 826–828. Published online 2009 Jun 7. doi: 10.1038/nn.2349

PMCID:: PMC2845930

Article PDF–1.2M

Select item 66085075.

Alternative Splicing Coupled Nonsense-Mediated Decay Generates Neuronal Cell Type-Specific Expression of SLM Proteins

Lisa Traunmüller, Caroline Bornmann, Peter Scheiffele

J Neurosci. 2014 Dec 10; 34(50): 16755–16761. doi: 10.1523/JNEUROSCI.3395-14.2014

PMCID:: PMC6608507

Article PDF–1.6M

Select item 46904936.

14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening

Nicholas J. Lavalley, Sunny R. Slone, Huiping Ding, Andrew B. West, Talene A. Yacoubian

Hum Mol Genet. 2016 Jan 1; 25(1): 109–122. Published online 2015 Nov 5. doi: 10.1093/hmg/ddv453

PMCID:: PMC4690493

Article PDF–1.1M

Select item 37280217.

Non-Motor and Motor Features in LRRK2 Transgenic Mice

Zoë Bichler, Han Chi Lim, Li Zeng, Eng King Tan

PLoS One. 2013; 8(7): e70249. Published online 2013 Jul 30. doi: 10.1371/journal.pone.0070249

PMCID:: PMC3728021

Article PDF–954K

Select item 69091828.

SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3′ UTR Isoforms in the Nervous System

Yoko Iijima, Masami Tanaka, Satoko Suzuki, David Hauser, Masayuki Tanaka, Chisa Okada, Masatoshi Ito, Noriko Ayukawa, Yuji Sato, Masato Ohtsuka, Peter Scheiffele, Takatoshi Iijima

iScience. 2019 Dec 20; 22: 318–335. Published online 2019 Nov 16. doi: 10.1016/j.isci.2019.11.028

PMCID:: PMC6909182

Article PDF–9.8M

Select item 36098729.

Interplay of LRRK2 with chaperone-mediated autophagy

Samantha J. Orenstein, Sheng-Hang Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernandez-Carasa, Etty Cortes, Lawrence S. Honig, William Dauer, Antonella Consiglio, Angel Raya, David Sulzer, Ana Maria Cuervo

Nat Neurosci. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Nat Neurosci. 2013 Apr; 16(4): 394–406. Published online 2013 Mar 3. doi: 10.1038/nn.3350

PMCID:: PMC3609872

Article PDF–3.4M

Select item 398635310.

Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice

Gonzalo Sanchez, Rafael K. Varaschin, Hansruedi Büeler, Paul C. Marcogliese, David S. Park, Louis-Eric Trudeau

PLoS One. 2014; 9(4): e94826. Published online 2014 Apr 14. doi: 10.1371/journal.pone.0094826

PMCID:: PMC3986353

Article PDF–1.1M

Select item 391252211.

Neuronal cell type–specific alternative splicing is regulated by the KH domain protein SLM1

Takatoshi Iijima, Yoko Iijima, Harald Witte, Peter Scheiffele

J Cell Biol. 2014 Feb 3; 204(3): 331–342. doi: 10.1083/jcb.201310136

PMCID:: PMC3912522

Article PDF–3.2M

Select item 382025612.

A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson’s Research

Marco A. S. Baptista, Kuldip D. Dave, Niketa P. Sheth, Shehan N. De Silva, Kirsten M. Carlson, Yasmin N. Aziz, Brian K. Fiske, Todd B. Sherer, Mark A. Frasier

Dis Model Mech. 2013 Nov; 6(6): 1316–1324. Published online 2013 Sep 12. doi: 10.1242/dmm.011940

PMCID:: PMC3820256

Article

Select item 516569813.

The function of orthologues of the human Parkinson’s disease gene LRRK2 across species: implications for disease modeling in preclinical research

Rebekah G. Langston, Iakov N. Rudenko, Mark R. Cookson

Biochem J. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Biochem J. 2016 Feb 1; 473(3): 221–232. doi: 10.1042/BJ20150985

PMCID:: PMC5165698

Article PDF–682K

Select item 324622014.

SAM68 regulates neuronal activity-dependent alternative splicing of Neurexin-1

Takatoshi Iijima, Karen Wu, Harald Witte, Yoko Hanno-Iijima, Timo Glatter, Stéphane Richard, Peter Scheiffele

Cell. Author manuscript; available in PMC 2012 Dec 23.

Published in final edited form as: Cell. 2011 Dec 23; 147(7): 1601–1614. doi: 10.1016/j.cell.2011.11.028

PMCID:: PMC3246220

Article PDF–6.2M

Select item 1583415.

Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis

Marco Di Fruscio, Taiping Chen, Stéphane Richard

Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6): 2710–2715. doi: 10.1073/pnas.96.6.2710

PMCID:: PMC15834

Article PDF–249K

Select item 639641416.

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis

Leslie O. Goodwin, Erik Splinter, Tiffany L. Davis, Rachel Urban, Hao He, Robert E. Braun, Elissa J. Chesler, Vivek Kumar, Max van Min, Juliet Ndukum, Vivek M. Philip, Laura G. Reinholdt, Karen Svenson, Jacqueline K. White, Michael Sasner, Cathleen Lutz, Stephen A. Murray

Genome Res. 2019 Mar; 29(3): 494–505. doi: 10.1101/gr.233866.117

PMCID:: PMC6396414

Article PDF–4.8M

Select item 388842817.

Gene and MicroRNA Transcriptome Analysis of Parkinson's Related LRRK2 Mouse Models

Véronique Dorval, Wim Mandemakers, Francis Jolivette, Laetitia Coudert, Rachid Mazroui, Bart De Strooper, Sébastien S. Hébert

PLoS One. 2014; 9(1): e85510. Published online 2014 Jan 10. doi: 10.1371/journal.pone.0085510

PMCID:: PMC3888428

Article PDF–1.1M

Select item 119959118.

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain

Adrienne E McKee, Emmanuel Minet, Charlene Stern, Shervin Riahi, Charles D Stiles, Pamela A Silver

BMC Dev Biol. 2005; 5: 14. Published online 2005 Jul 20. doi: 10.1186/1471-213X-5-14

PMCID:: PMC1199591

Article PDF–2.0M

Select item 2980019.

Database resources of the National Center for Biotechnology Information

David L. Wheeler, Deanna M. Church, Alex E. Lash, Detlef D. Leipe, Thomas L. Madden, Joan U. Pontius, Gregory D. Schuler, Lynn M. Schriml, Tatiana A. Tatusova, Lukas Wagner, Barbara A. Rapp

Nucleic Acids Res. 2001 Jan 1; 29(1): 11–16. doi: 10.1093/nar/29.1.11

PMCID:: PMC29800

Article PDF–101K

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163