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Select item 95882421.

Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin

Daniele Caracciolo, Giada Juli, Caterina Riillo, Adriana Coricello, Francesca Vasile, Sara Pollastri, Roberta Rocca, Francesca Scionti, Nicoletta Polerà, Katia Grillone, Mariamena Arbitrio, Nicoletta Staropoli, Basilio Caparello, Domenico Britti, Giovanni Loprete, Giosuè Costa, Maria Teresa Di Martino, Stefano Alcaro, Pierosandro Tagliaferri, Pierfrancesco Tassone

J Transl Med. 2022; 20: 482. Published online 2022 Oct 22. doi: 10.1186/s12967-022-03705-z

PMCID:: PMC9588242

Article PDF–3.5M

Select item 37722062.

Mitochondrial DNA Ligase Is Dispensable for the Viability of Cultured Cells but Essential for mtDNA Maintenance

Inna N. Shokolenko, Rafik Z. Fayzulin, Sachin Katyal, Peter J. McKinnon, Glenn L. Wilson, Mikhail F. Alexeyev

J Biol Chem. 2013 Sep 13; 288(37): 26594–26605. Published online 2013 Jul 24. doi: 10.1074/jbc.M113.472977

PMCID:: PMC3772206

Article PDF–2.3M

Select item 14890033.

Early Embryonic Lethality Due to Targeted Inactivation of DNA Ligase III

Nahum Puebla-Osorio, Devin B. Lacey, Frederick W. Alt, Chengming Zhu

Mol Cell Biol. 2006 May; 26(10): 3935–3941. doi: 10.1128/MCB.26.10.3935-3941.2006

PMCID:: PMC1489003

Article PDF–381K

Select item 90982604.

Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

Mariana Paes Dias, Vivek Tripathi, Ingrid van der Heijden, Ke Cong, Eleni-Maria Manolika, Jinhyuk Bhin, Ewa Gogola, Panagiotis Galanos, Stefano Annunziato, Cor Lieftink, Miguel Andújar-Sánchez, Sanjiban Chakrabarty, Graeme C.M. Smith, Marieke van de Ven, Roderick L. Beijersbergen, Jirina Bartkova, Sven Rottenberg, Sharon Cantor, Jiri Bartek, Arnab Ray Chaudhuri, Jos Jonkers

Mol Cell. Author manuscript; available in PMC 2022 May 12.

Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4692–4708.e9. Published online 2021 Sep 22. doi: 10.1016/j.molcel.2021.09.005

PMCID:: PMC9098260

Article PDF–2.9M

Select item 51564825.

Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

Mansour Akbari, Guido Keijzers, Scott Maynard, Morten Scheibye-Knudsen, Claus Desler, Ian D. Hickson, Vilhelm A. Bohr

DNA Repair (Amst) Author manuscript; available in PMC 2016 Dec 14.

Published in final edited form as: DNA Repair (Amst). 2014 Apr; 16: 44–53. Published online 2014 Feb 27. doi: 10.1016/j.dnarep.2014.01.015

PMCID:: PMC5156482

Article PDF–1.1M

Select item 62115876.

Intrinsic mitochondrial DNA repair defects in Ataxia Telangiectasia

Nilesh K. Sharma, Maria Lebedeva, Terace Thomas, Olga A. Kovalenko, Jeffrey D. Stumpf, Gerald S. Shadel, Janine H. Santos

DNA Repair (Amst) Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2014 Jan; 13: 22–31. Published online 2013 Dec 15. doi: 10.1016/j.dnarep.2013.11.002

PMCID:: PMC6211587

Article PDF–924K

Select item 32892967.

Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

Cristian Boboila, Valentyn Oksenych, Monica Gostissa, Jing H. Wang, Shan Zha, Yu Zhang, Hua Chai, Cheng-Sheng Lee, Mila Jankovic, Liz-Marie Albertorio Saez, Michel C. Nussenzweig, Peter J. McKinnon, Frederick W. Alt, Bjoern Schwer

Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7): 2473–2478. Published online 2012 Jan 30. doi: 10.1073/pnas.1121470109

Correction in:: Proc Natl Acad Sci U S A. 2013 Apr 2; 110(14): 5731.

PMCID:: PMC3289296

Article PDF–426K

Select item 32617578.

Crucial roles for DNA ligase III in mitochondria but not in XRCC1-dependent repair

Deniz Simsek, Amy Furda, Yankun Gao, Jérôme Artus, Erika Brunet, Anna-Katerina Hadjantonakis, Bennett Van Houten, Stewart Shuman, Peter J. McKinnon, Maria Jasin

Nature. Author manuscript; available in PMC 2012 Jan 19.

Published in final edited form as: Nature. 2011 Mar 10; 471(7337): 245–248. doi: 10.1038/nature09794

PMCID:: PMC3261757

Article PDF–875K

Select item 51255559.

Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining

Ylli Doksani, Titia de Lange

Cell Rep. Author manuscript; available in PMC 2016 Nov 28.

Published in final edited form as: Cell Rep. 2016 Nov 1; 17(6): 1646–1656. doi: 10.1016/j.celrep.2016.10.008

PMCID:: PMC5125555

Article PDF–2.8M

Select item 310720210.

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

Deniz Simsek, Erika Brunet, Sunnie Yan-Wai Wong, Sachin Katyal, Yankun Gao, Peter J. McKinnon, Jacqueline Lou, Lei Zhang, James Li, Edward J. Rebar, Philip D. Gregory, Michael C. Holmes, Maria Jasin

PLoS Genet. 2011 Jun; 7(6): e1002080. Published online 2011 Jun 2. doi: 10.1371/journal.pgen.1002080

PMCID:: PMC3107202

Article PDF–1.0M

Select item 23182411.

An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination.

Z B Mackey, W Ramos, D S Levin, C A Walter, J R McCarrey, A E Tomkinson

Mol Cell Biol. 1997 Feb; 17(2): 989–998. doi: 10.1128/mcb.17.2.989

PMCID:: PMC231824

Summary PDF–6.8M

Select item 352627712.

Pol β associated complex and base excision repair factors in mouse fibroblasts

Rajendra Prasad, Jason G. Williams, Esther W. Hou, Samuel H. Wilson

Nucleic Acids Res. 2012 Dec; 40(22): 11571–11582. Published online 2012 Oct 5. doi: 10.1093/nar/gks898

PMCID:: PMC3526277

Article PDF–2.3M

Select item 307942913.

DNA Ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

Yankun Gao, Sachin Katyal, Youngsoo Lee, Jingfeng Zhao, Jerold E. Rehg, Helen R. Russell, Peter J. McKinnon

Nature. Author manuscript; available in PMC 2011 Sep 10.

Published in final edited form as: Nature. 2011 Mar 10; 471(7337): 240–244. doi: 10.1038/nature09773

PMCID:: PMC3079429

Article PDF–2.6M

Select item 407400914.

Aberrant Topoisomerase-1-DNA Lesions are Pathogenic in Neurodegenerative Genome Instability Syndromes

Sachin Katyal, Youngsoo Lee, Karin C. Nitiss, Susanna M. Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R. Russell, John H. J. Petrini, John L. Nitiss, Peter J. McKinnon

Nat Neurosci. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Neurosci. 2014 Jun; 17(6): 813–821. Published online 2014 May 4. doi: 10.1038/nn.3715

PMCID:: PMC4074009

Article PDF–2.2M

Select item 283128415.

Genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

Youngsoo Lee, Sachin Katyal, Yang Li, Sherif F. El-Khamisy, Helen R. Russell, Keith W. Caldecott, Peter J. McKinnon

Nat Neurosci. Author manuscript; available in PMC 2010 Mar 3.

Published in final edited form as: Nat Neurosci. 2009 Aug; 12(8): 973–980. Published online 2009 Jul 26. doi: 10.1038/nn.2375

PMCID:: PMC2831284

Article PDF–2.4M

Select item 286024416.

An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

Mercedes Pardo, Benjamin Lang, Lu Yu, Haydn Prosser, Allan Bradley, M. Madan Babu, Jyoti Choudhary

Cell Stem Cell. 2010 Apr 2; 6(4): 382–395. doi: 10.1016/j.stem.2010.03.004

PMCID:: PMC2860244

Article

Select item 451183317.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga

Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859

PMCID:: PMC4511833

Article PDF–2.2M

Select item 286024318.

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

Debbie L.C. van den Berg, Tim Snoek, Nick P. Mullin, Adam Yates, Karel Bezstarosti, Jeroen Demmers, Ian Chambers, Raymond A. Poot

Cell Stem Cell. 2010 Apr 2; 6(4): 369–381. doi: 10.1016/j.stem.2010.02.014

PMCID:: PMC2860243

Article

Select item 452520319.

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells

Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger

Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776

PMCID:: PMC4525203

Article PDF–1.9M

Select item 874425720.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Article PDF–6.0M

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