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Select item 108452071.

Gut ribotoxic stress responses facilitate dyslipidemia via metabolic reprogramming: an environmental health prediction

Juil Kim, Hoyoung Jeong, Navin Ray, Ki-Hyung Kim, Yuseok Moon

Theranostics. 2024; 14(3): 1289–1311. Published online 2024 Jan 20. doi: 10.7150/thno.88586

PMCID:: PMC10845207

Article PDF–13M

Select item 106052462.

CETP Expression in Bone-Marrow-Derived Cells Reduces the Inflammatory Features of Atherosclerosis in Hypercholesterolemic Mice

Thiago Rentz, Gabriel G. Dorighello, Renata R. dos Santos, Lohanna M. Barreto, Israelle N. Freitas, Carolina M. Lazaro, Daniela S. Razolli, Patricia M. Cazita, Helena C. F. Oliveira

Biomolecules. 2023 Oct; 13(10): 1556. Published online 2023 Oct 22. doi: 10.3390/biom13101556

PMCID:: PMC10605246

Article PDF–2.0M

Select item 103468593.

Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody

Florine Seidel, Kees Fluiter, Robert Kleemann, Nicole Worms, Anita van Nieuwkoop, Martien P. M. Caspers, Nikolaos Grigoriadis, Amanda J. Kiliaan, Frank Baas, Iliana Michailidou, Martine C. Morrison

Front Cell Neurosci. 2023; 17: 1205261. Published online 2023 Jun 29. doi: 10.3389/fncel.2023.1205261

Correction in:: Front Cell Neurosci. 2023; 17: 1267913.

PMCID:: PMC10346859

Article PDF–4.4M

Select item 102183344.

Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice

José A. Inia, Geurt Stokman, Martine C. Morrison, Nicole Worms, Lars Verschuren, Martien P. M. Caspers, Aswin L. Menke, Louis Petitjean, Li Chen, Mathieu Petitjean, J. Wouter Jukema, Hans M. G. Princen, Anita M. van den Hoek

Int J Mol Sci. 2023 May; 24(10): 8494. Published online 2023 May 9. doi: 10.3390/ijms24108494

PMCID:: PMC10218334

Article PDF–3.7M

Select item 101604825.

DNA methylation changes underlie the long-term association between periodontitis and atherosclerotic cardiovascular disease

Mohamed Omar, Maria Alexiou, Umar R. Rekhi, Konrad Lehmann, Aneesh Bhardwaj, Cole Delyea, Shokrollah Elahi, Maria Febbraio

Front Cardiovasc Med. 2023; 10: 1164499. Published online 2023 Apr 21. doi: 10.3389/fcvm.2023.1164499

PMCID:: PMC10160482

Article PDF–2.5M

Select item 101196126.

PANDORA-Seq unveilsthe hidden small noncoding RNA landscape in atherosclerosis of LDL receptor-deficient mice

Rebecca Hernandez, Junchao Shi, Jingwei Liu, Xiuchun Li, Jake Wu, Linlin Zhao, Tong Zhou, Qi Chen, Changcheng Zhou

J Lipid Res. 2023 Apr; 64(4): 100352. Published online 2023 Mar 4. doi: 10.1016/j.jlr.2023.100352

PMCID:: PMC10119612

Article PDF–3.5M

Select item 99475387.

Paradoxical reduction of plasma lipids and atherosclerosis in mice with adenine-induced chronic kidney disease and hypercholesterolemia

Mugdha V. Padalkar, Alexandra H. Tsivitis, Ylona Gelfman, Mariya Kasiyanyk, Neil Kaungumpillil, Danyang Ma, Michael Gao, Kelly A. Borges, Puneet Dhaliwal, Saud Nasruddin, Sruthi Saji, Hina Gilani, Eric J. Schram, Mohnish Singh, Maria M. Plummer, Olga V. Savinova

Front Cardiovasc Med. 2023; 10: 1088015. Published online 2023 Feb 9. doi: 10.3389/fcvm.2023.1088015

PMCID:: PMC9947538

Article PDF–8.8M

Select item 98182998.

Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr^−/− Mice

Parameswaran Gangadharan Sreekumar, Feng Su, Christine Spee, Eduardo Araujo, Steven Nusinowitz, Srinivasa T Reddy, Ram Kannan

Cells. 2023 Jan; 12(1): 43. Published online 2022 Dec 22. doi: 10.3390/cells12010043

PMCID:: PMC9818299

Article PDF–7.6M

Select item 96265549.

Blockade of the BLT1-LTB₄ axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr^−/− mice

Marie A. C. Depuydt, Femke D. Vlaswinkel, Esmeralda Hemme, Lucie Delfos, Mireia N. A. Bernabé Kleijn, Peter J. van Santbrink, Amanda C. Foks, Bram Slütter, Johan Kuiper, Ilze Bot

Sci Rep. 2022; 12: 18362. Published online 2022 Nov 1. doi: 10.1038/s41598-022-23162-4

PMCID:: PMC9626554

Article PDF–1.7M

Select item 958919810.

BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice

Eliza Bollinger, Matthew Peloquin, Jenna Libera, Bina Albuquerque, Evanthia Pashos, Arun Shipstone, Angela Hadjipanayis, Zhongyuan Sun, Gang Xing, Michelle Clasquin, John C. Stansfield, Brendan Tierney, Steven Gernhardt, C. Parker Siddall, Timothy Greizer, Frank J. Geoly, Sarah R. Vargas, Lily C. Gao, George Williams, Mackenzie Marshall, Amy Rosado, Claire Steppan, Kevin J. Filipski, Bei B. Zhang, Russell A. Miller, Rachel J. Roth Flach

Mol Metab. 2022 Dec; 66: 101611. Published online 2022 Oct 8. doi: 10.1016/j.molmet.2022.101611

PMCID:: PMC9589198

Article PDF–3.2M

Select item 950626611.

Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice

Florine Seidel, Robert Kleemann, Wim van Duyvenvoorde, Nikki van Trigt, Nanda Keijzer, Sandra van der Kooij, Cees van Kooten, Lars Verschuren, Aswin Menke, Amanda J. Kiliaan, Johnathan Winter, Timothy R. Hughes, B. Paul Morgan, Frank Baas, Kees Fluiter, Martine C. Morrison

Int J Mol Sci. 2022 Sep; 23(18): 10736. Published online 2022 Sep 14. doi: 10.3390/ijms231810736

PMCID:: PMC9506266

Article PDF–3.2M

Select item 949982912.

The low-density lipoprotein receptor–mTORC1 axis coordinates CD8⁺ T cell activation

Fabrizia Bonacina, Annalisa Moregola, Monika Svecla, David Coe, Patrizia Uboldi, Sara Fraire, Simona Beretta, Giangiacomo Beretta, Fabio Pellegatta, Alberico Luigi Catapano, Federica M. Marelli-Berg, Giuseppe Danilo Norata

J Cell Biol. 2022 Nov 7; 221(11): e202202011. Published online 2022 Sep 21. doi: 10.1083/jcb.202202011

PMCID:: PMC9499829

Article PDF–7.9M

Select item 936937013.

Differential Effect of Dietary Supplementation with a Soybean Oil Enriched in Oleic Acid versus Linoleic Acid on Plasma Lipids and Atherosclerosis in LDLR-Deficient Mice

Zhi-Hong Yang, Kimball Nill, Yuki Takechi-Haraya, Martin P. Playford, David Nguyen, Zu-Xi Yu, Milton Pryor, Jingrong Tang, Krishna Vamsi Rojulpote, Nehal N. Mehta, Han Wen, Alan T. Remaley

Int J Mol Sci. 2022 Aug; 23(15): 8385. Published online 2022 Jul 29. doi: 10.3390/ijms23158385

PMCID:: PMC9369370

Article PDF–1.4M

Select item 917408814.

Mild Mitochondrial Uncoupling Decreases Experimental Atherosclerosis, A Proof of Concept

Gabriel G Dorighello, Juliana C Rovani, Bruno A Paim, Thiago Rentz, Leandro H P Assis, Anibal E Vercesi, Helena C F Oliveira

J Atheroscler Thromb. 2022 Jun 1; 29(6): 825–838. Published online 2021 Jun 4. doi: 10.5551/jat.62796

PMCID:: PMC9174088

Article PDF–626K

Select item 900840415.

CagA⁺Helicobacter pylori, Not CagA^–Helicobacter pylori, Infection Impairs Endothelial Function Through Exosomes-Mediated ROS Formation

Xiujuan Xia, Linfang Zhang, Hao Wu, Feng Chen, Xuanyou Liu, Huifang Xu, Yuqi Cui, Qiang Zhu, Meifang Wang, Hong Hao, De-Pei Li, William P. Fay, Luis A. Martinez-Lemus, Michael A. Hill, Canxia Xu, Zhenguo Liu

Front Cardiovasc Med. 2022; 9: 881372. Published online 2022 Mar 31. doi: 10.3389/fcvm.2022.881372

PMCID:: PMC9008404

Article PDF–5.8M

Select item 889226816.

Amino acid starvation‐induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

Ye Chen, Xiao Wu, Jing Zhang, Guopin Pan, Xiaoyun Wang, Xiaosun Guo, Jianli Wang, Xiaopei Cui, Haiqing Gao, Mei Cheng, Jingwen Yang, Cheng Zhang, Fan Jiang

EMBO Rep. 2022 Mar 3; 23(3): e53373. Published online 2022 Jan 7. doi: 10.15252/embr.202153373

PMCID:: PMC8892268

Article PDF–6.8M

Select item 881112817.

Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification

Takeshi Tanaka, Takaharu Asano, Takehito Okui, Shiori Kuraoka, Sasha A. Singh, Masanori Aikawa, Elena Aikawa

Front Cardiovasc Med. 2021; 8: 826529. Published online 2022 Jan 20. doi: 10.3389/fcvm.2021.826529

PMCID:: PMC8811128

Article PDF–3.3M

Select item 875277118.

High fat diet-induced obesity prolongs critical stages of the spermatogenic cycle in a Ldlr^−/−.Leiden mouse model

D. Komninos, L. Ramos, G. W. van der Heijden, M. C. Morrison, R. Kleemann, A. E. van Herwaarden, A. J. Kiliaan, I. A. C. Arnoldussen

Sci Rep. 2022; 12: 430. Published online 2022 Jan 11. doi: 10.1038/s41598-021-04069-y

PMCID:: PMC8752771

Article PDF–5.4M

Select item 874871719.

PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice

Laura M. de Jong, Zhengzheng Zhang, Yvette den Hartog, Timothy J. P. Sijsenaar, Renata Martins Cardoso, Martijn L. Manson, Thomas Hankemeier, Peter W. Lindenburg, Daniela C. F. Salvatori, Miranda Van Eck, Menno Hoekstra

Sci Rep. 2022; 12: 483. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04524-w

PMCID:: PMC8748717

Article PDF–5.1M

Select item 869267220.

The Association and Pathogenesis of SERPINA3 in Coronary Artery Disease

Bo Li, Zhijun Lei, You Wu, Bingyu Li, Ming Zhai, Yuan Zhong, Peinan Ju, Wenxin Kou, Yefei Shi, Xianling Zhang, Wenhui Peng

Front Cardiovasc Med. 2021; 8: 756889. Published online 2021 Dec 8. doi: 10.3389/fcvm.2021.756889

PMCID:: PMC8692672

Article PDF–2.3M

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