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Items: 1 to 20 of 65

1.
TREK-1 protects the heart against ischemia reperfusion-induced injury and from adverse remodeling after myocardial infarction
Samuel Kamatham, Christopher M. Waters, Andreas Schwingshackl, Salvatore Mancarella
Pflugers Arch. Author manuscript; available in PMC 2022 Apr 11.
Published in final edited form as: Pflugers Arch. 2019 Oct; 471(10): 1263–1272. Published online 2019 Sep 12. doi: 10.1007/s00424-019-02306-y
PMCID:
PMC8996126
ArticlePDF–1.0M
2.
TREK-1 null impairs neuronal excitability, synaptic plasticity, and cognitive function
Wei Wang, Conrad M. Kiyoshi, Yixing Du, Anne T. Taylor, Erica R. Sheehan, Xiao Wu, Min Zhou
Mol Neurobiol. Author manuscript; available in PMC 2022 Feb 2.
Published in final edited form as: Mol Neurobiol. 2020 Mar; 57(3): 1332–1346. Published online 2019 Nov 15. doi: 10.1007/s12035-019-01828-x
PMCID:
PMC8808335
ArticlePDF–1.9M
3.
Genetic and pharmacological inhibition of two‐pore domain potassium channel TREK‐1 alters depression‐related behaviors and neuronal plasticity in the hippocampus in mice
Fangfang Wu, Hongbin Sun, Weigang Gong, Xiaoli Li, Zhaohui Pan, Han Shan, Zhijun Zhang
CNS Neurosci Ther. 2021 Feb; 27(2): 220–232. Published online 2020 Aug 30. doi: 10.1111/cns.13450
PMCID:
PMC7816204
ArticlePDF–3.0M
4.
K2P2.1 (TREK-1) potassium channel activation protects against hyperoxia-induced lung injury
Tatiana Zyrianova, Benjamin Lopez, Riccardo Olcese, John Belperio, Christopher M. Waters, Leanne Wong, Victoria Nguyen, Sriharsha Talapaneni, Andreas Schwingshackl
Sci Rep. 2020; 10: 22011. Published online 2020 Dec 15. doi: 10.1038/s41598-020-78886-y
PMCID:
PMC7738539
ArticlePDF–2.5M
5.
Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification
Marianna Dionisi, Federico Alessandro Ruffinatti, Beatrice Riva, Dmitry Lim, Annalisa Canta, Cristina Meregalli, Giulia Fumagalli, Laura Monza, Antonio Ferrer-Montiel, Asia Fernandez-Carvajal, Guido Cavaletti, Armando A. Genazzani, Carla Distasi
Int J Mol Sci. 2020 Oct; 21(19): 7164. Published online 2020 Sep 28. doi: 10.3390/ijms21197164
PMCID:
PMC7584002
ArticlePDF–2.0M
6.
TREK1 channel activation as a new analgesic strategy devoid of opioid adverse effects
Jérôme Busserolles, Ismail Ben Soussia, Laetitia Pouchol, Nicolas Marie, Mathieu Meleine, Maïly Devilliers, Céline Judon, Julien Schopp, Loïc Clémenceau, Laura Poupon, Eric Chapuy, Serge Richard, Florence Noble, Florian Lesage, Sylvie Ducki, Alain Eschalier, Stéphane Lolignier
Br J Pharmacol. 2020 Oct; 177(20): 4782–4795. Published online 2020 Sep 21. doi: 10.1111/bph.15243
Correction in:
Br J Pharmacol. 2020 Nov; 177(22): 5246.
PMCID:
PMC7520446
ArticlePDF–8.3M
7.
PIP2 Mediated Inhibition of TREK Potassium Currents by Bradykinin in Mouse Sympathetic Neurons
Paula Rivas-Ramírez, Antonio Reboreda, Lola Rueda-Ruzafa, Salvador Herrera-Pérez, J. Antonio Lamas
Int J Mol Sci. 2020 Jan; 21(2): 389. Published online 2020 Jan 8. doi: 10.3390/ijms21020389
PMCID:
PMC7014146
ArticlePDF–5.7M
8.
Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel
Ricardo H. Pineda, Joseph Hypolite, Sanghee Lee, Alonso Carrasco, Jr, Nao Iguchi, Randall B. Meacham, Anna P. Malykhina
BMC Urol. 2019; 19: 40. Published online 2019 May 21. doi: 10.1186/s12894-019-0475-3
PMCID:
PMC6528348
ArticlePDF–4.4M
9.
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice
Yongkang Fang, Yeye Tian, Qibao Huang, Yue Wan, Li Xu, Wei Wang, Dengji Pan, Suiqiang Zhu, Minjie Xie
J Neuroinflammation. 2019; 16: 96. Published online 2019 May 9. doi: 10.1186/s12974-019-1485-5
PMCID:
PMC6506965
ArticlePDF–8.5M
10.
Two‐Pore K+ Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability
Sathya D. Unudurthi, Xiangqiong Wu, Lan Qian, Foued Amari, Birce Onal, Ning Li, Michael A. Makara, Sakima A. Smith, Jedidiah Snyder, Vadim V. Fedorov, Vincenzo Coppola, Mark E. Anderson, Peter J. Mohler, Thomas J. Hund
J Am Heart Assoc. 2016 Apr; 5(4): e002865. Published online 2016 Apr 20. doi: 10.1161/JAHA.115.002865
PMCID:
PMC4859279
ArticlePDF–2.5M
11.
A potassium leak channel silences hyperactive neurons and ameliorates status epilepticus
Deblina Dey, Veit-Simon Eckle, Iuliia Vitko, Kyle A. Sullivan, Zofia M. Lasiecka, Bettina Winckler, Ruth L. Stornetta, John M. Williamson, Jaideep Kapur, Edward Perez-Reyes
Epilepsia. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Epilepsia. 2014 Feb; 55(2): 203–213. Published online 2013 Dec 2. doi: 10.1111/epi.12472
PMCID:
PMC4161023
ArticlePDF–1.0M
12.
The Purified Mechanosensitive Channel TREK-1 Is Directly Sensitive to Membrane Tension
Catherine Berrier, Alexandre Pozza, Agnes de Lacroix de Lavalette, Solenne Chardonnet, Agnes Mesneau, Christine Jaxel, Marc le Maire, Alexandre Ghazi
J Biol Chem. 2013 Sep 20; 288(38): 27307–27314. Published online 2013 Jul 29. doi: 10.1074/jbc.M113.478321
PMCID:
PMC3779726
ArticlePDF–1.0M
13.
Metabolic and thermal stimuli control K2P2.1 (TREK-1) through modular sensory and gating domains
Sviatoslav N Bagriantsev, Kimberly A Clark, Daniel L Minor, Jr
EMBO J. 2012 Aug 1; 31(15): 3297–3308. Published online 2012 Jun 22. doi: 10.1038/emboj.2012.171
PMCID:
PMC3411076
ArticlePDF–1.6M
14.
Regulation and function of the two-pore-domain (K2P) potassium channel Trek-1 in alveolar epithelial cells
Andreas Schwingshackl, Bin Teng, Manik Ghosh, Alina Nico West, Patrudu Makena, Vijay Gorantla, Scott E. Sinclair, Christopher M. Waters
Am J Physiol Lung Cell Mol Physiol. 2012 Jan 1; 302(1): L93–L102. Published online 2011 Sep 23. doi: 10.1152/ajplung.00078.2011
PMCID:
PMC3349376
Article
15.
Multiple modalities converge on a common gate to control K2P channel function
Sviatoslav N Bagriantsev, Rémi Peyronnet, Kimberly A Clark, Eric Honoré, Daniel L Minor, Jr
EMBO J. 2011 Aug 31; 30(17): 3594–3606. Published online 2011 Jul 15. doi: 10.1038/emboj.2011.230
PMCID:
PMC3181481
ArticlePDF–1.8M
16.
Reciprocal Regulation of TREK-1 Channels by Arachidonic Acid and CRH in Mouse Corticotropes
Andy K. Lee, James L. Smart, Marcelo Rubinstein, Malcolm J. Low, Amy Tse
Endocrinology. 2011 May; 152(5): 1901–1910. Published online 2011 Feb 22. doi: 10.1210/en.2010-1066
PMCID:
PMC3075932
Article
17.
Traumatic brain injury in mice lacking the K channel, TREK-1
Khodadad Namiranian, Christa D Brink, Jerry Clay Goodman, Claudia S Robertson, Robert M Bryan, Jr
J Cereb Blood Flow Metab. 2011 Mar; 31(3): e1–e6. Published online 2010 Dec 15. doi: 10.1038/jcbfm.2010.223
PMCID:
PMC3063636
ArticlePDF–333K
18.
The stretch-dependent potassium channel TREK-1 and its function in murine myometrium
Kevin Monaghan, Salah A Baker, Laura Dwyer, William C Hatton, Kyung Sik Park, Kenton M Sanders, Sang Don Koh
J Physiol. 2011 Mar 1; 589(Pt 5): 1221–1233. Published online 2011 Jan 10. doi: 10.1113/jphysiol.2010.203869
PMCID:
PMC3060598
ArticlePDF–662K
19.
Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1: Comparisons with structural models
Grigory Maksaev, Adina Milac, Andriy Anishkin, H Robert Guy, Sergei Sukharev
Channels (Austin) 2011 Jan-Feb; 5(1): 34–42. Published online 2011 Jan 1. doi: 10.4161/chan.5.1.13906
PMCID:
PMC3052206
ArticlePDF–2.2M
20.
Cerebrovascular responses in mice deficient in the potassium channel, TREK-1
Khodadad Namiranian, Eric E. Lloyd, Randy F. Crossland, Sean P. Marrelli, George E. Taffet, Anilkumar K. Reddy, Craig J. Hartley, Robert M. Bryan, Jr.
Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2): R461–R469. Published online 2010 Mar 31. doi: 10.1152/ajpregu.00057.2010
PMCID:
PMC2928619
Article

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