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Select item 99844851.

Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy

Alessandro Bortolami, Wei Yu, Elena Forzisi, Koray Ercan, Ritik Kadakia, Madhuvika Murugan, Denise Fedele, Irving Estevez, Detlev Boison, Mladen-Roko Rasin, Federico Sesti

Cell Death Differ. 2023 Mar; 30(3): 687–701. Published online 2022 Oct 7. doi: 10.1038/s41418-022-01072-2

PMCID:: PMC9984485

Article PDF–7.5M

Select item 84644982.

Kv2.1 expression in giant reticular neurons of the postnatal mouse brain

Ting Ding, Ana Maria Magarinos, Lee-Ming Kow, Teresa A. Milner, Donald W. Pfaff

J Chem Neuroanat. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: J Chem Neuroanat. 2021 Nov; 117: 102005. Published online 2021 Jul 17. doi: 10.1016/j.jchemneu.2021.102005

PMCID:: PMC8464498

Article PDF–1.1M

Select item 78459213.

Loss of the K⁺ channel K_v2.1 greatly reduces outward dark current and causes ionic dysregulation and degeneration in rod photoreceptors

Christopher Fortenbach, Gabriel Peinado Allina, Camilla M. Shores, Sarah J. Karlen, Eric B. Miller, Hannah Bishop, James S. Trimmer, Marie E. Burns, Edward N. Pugh, Jr.

J Gen Physiol. 2021 Feb 1; 153(2): e202012687. Published online 2021 Jan 27. doi: 10.1085/jgp.202012687

PMCID:: PMC7845921

Article PDF–6.7M

Select item 57099984.

Disruption of K_V2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents

Jason A. Justice, Anthony J. Schulien, Kai He, Karen A. Hartnett, Elias Aizenman, Niyathi H. Shah

Neuroscience. Author manuscript; available in PMC 2018 Jun 23.

Published in final edited form as: Neuroscience. 2017 Jun 23; 354: 158–167. Published online 2017 Apr 28. doi: 10.1016/j.neuroscience.2017.04.034

PMCID:: PMC5709998

Article PDF–1.1M

Select item 50988435.

Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury

Wei Yu, Randika Parakramaweera, Shavonne Teng, Manasa Gowda, Yashsavi Sharad, Smita Thakker-Varia, Janet Alder, Federico Sesti

J Neurosci. 2016 Oct 26; 36(43): 11084–11096. doi: 10.1523/JNEUROSCI.2273-16.2016

Correction in:: J Neurosci. 2024 Mar 13; 44(11): e0282242024.

PMCID:: PMC5098843

Article PDF–2.7M

Select item 43672906.

Selective Down-regulation of K_V2.1 Function Contributes to Enhanced Arterial Tone during Diabetes

Madeline Nieves-Cintrón, Matthew A. Nystoriak, Maria Paz Prada, Kenneth Johnson, William Fayer, Mark L. Dell'Acqua, John D. Scott, Manuel F. Navedo

J Biol Chem. 2015 Mar 20; 290(12): 7918–7929. Published online 2015 Feb 10. doi: 10.1074/jbc.M114.622811

Correction in:: J Biol Chem. 2016 Mar 4; 291(10): 4912.

PMCID:: PMC4367290

Article PDF–2.3M

Select item 35676637.

Molecular Mechanisms Underlying the Apoptotic Effect of KCNB1 K⁺ Channel Oxidation

Xilong Wu, Berenice Hernandez-Enriquez, Michelle Banas, Robin Xu, Federico Sesti

J Biol Chem. 2013 Feb 8; 288(6): 4128–4134. Published online 2012 Dec 29. doi: 10.1074/jbc.M112.440933

PMCID:: PMC3567663

Article PDF–910K

Select item 26924168.

K_v2.1 and silent K_v subunits underlie the delayed rectifier K⁺ current in cultured small mouse DRG neurons

Elke Bocksteins, Adam L. Raes, Gerda Van de Vijver, Tine Bruyns, Pierre-Paul Van Bogaert, Dirk J. Snyders

Am J Physiol Cell Physiol. 2009 Jun; 296(6): C1271–C1278. Published online 2009 Apr 8. doi: 10.1152/ajpcell.00088.2009

PMCID:: PMC2692416

Article

Select item 89814579.

Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons

Zhao‐Wei Sun, Jarod M. Waybright, Serap Beldar, Lu Chen, Caroline A. Foley, Jacqueline L. Norris‐Drouin, Tian‐Jie Lyu, Aiping Dong, Jinrong Min, Yu‐Pu Wang, Lindsey I. James, Yun Wang

Adv Sci (Weinh) 2022 Apr; 9(10): 2104317. Published online 2022 Feb 4. doi: 10.1002/advs.202104317

Correction in:: Adv Sci (Weinh). 2023 Sep; 10(25): 2304061.

PMCID:: PMC8981457

Article PDF–6.5M

Select item 812444710.

Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K⁺ Channel Subunits Kv8.2 and K2.1

Xiaotian Jiang, Rabab Rashwan, Valentina Voigt, Jeanne Nerbonne, David M. Hunt, Livia S. Carvalho

Int J Mol Sci. 2021 May; 22(9): 4877. Published online 2021 May 5. doi: 10.3390/ijms22094877

PMCID:: PMC8124447

Article PDF–8.1M

Select item 772592211.

Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant

Nicole A. Hawkins, Sunita N Misra, Manuel Jurado, Seok Kyu Kang, Nicholas C. Vierra, Kimberly Nguyen, Lisa Wren, Alfred L. George, Jr., James S. Trimmer, Jennifer A. Kearney

Neurobiol Dis. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Neurobiol Dis. 2021 Jan; 147: 105141. Published online 2020 Oct 22. doi: 10.1016/j.nbd.2020.105141

PMCID:: PMC7725922

Article PDF–1.6M

Select item 703562312.

Kv2.1 channels play opposing roles in regulating membrane potential, Ca²⁺ channel function, and myogenic tone in arterial smooth muscle

Samantha C. O’Dwyer, Stephanie Palacio, Collin Matsumoto, Laura Guarina, Nicholas R. Klug, Sendoa Tajada, Barbara Rosati, David McKinnon, James S. Trimmer, L. Fernando Santana

Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3858–3866. Published online 2020 Feb 3. doi: 10.1073/pnas.1917879117

PMCID:: PMC7035623

Article PDF–1.7M

Select item 649793413.

Clustered Kv2.1 decreases dopamine transporter activity and internalization

Joseph J. Lebowitz, Jose A. Pino, Phillip M. Mackie, Min Lin, Cheyenne Hurst, Keeley Divita, Anthony T. Collins, Dimitri N. Koutzoumis, Gonzalo E. Torres, Habibeh Khoshbouei

J Biol Chem. 2019 Apr 26; 294(17): 6957–6971. Published online 2019 Mar 1. doi: 10.1074/jbc.RA119.007441

PMCID:: PMC6497934

Article PDF–5.9M

Select item 578042914.

Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons

Hannah I. Bishop, Melanie M. Cobb, Michael Kirmiz, Laxmi K. Parajuli, Danielle Mandikian, Ashleigh M. Philp, Mikhail Melnik, Juha Kuja-Panula, Heikki Rauvala, Ryuichi Shigemoto, Karl D. Murray, James S. Trimmer

Front Mol Neurosci. 2018; 11: 1. Published online 2018 Jan 19. doi: 10.3389/fnmol.2018.00001

PMCID:: PMC5780429

Article PDF–6.1M

Select item 547758315.

Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain

Wei Yu, Manasa Gowda, Yashsavi Sharad, Surindo A Singh, Federico Sesti

Cell Death Dis. 2017 Apr; 8(4): e2737. Published online 2017 Apr 6. doi: 10.1038/cddis.2017.160

Correction in:: Cell Death Dis. 2019 Oct; 10(10): 756.

PMCID:: PMC5477583

Article PDF–1.5M

Select item 413946016.

Cell Type Specific Spatial and Functional Coupling Between Mammalian Brain Kv2.1 K⁺ Channels and Ryanodine Receptors

Danielle Mandikian, Elke Bocksteins, Laxmi Kumar Parajuli, Hannah I. Bishop, Oscar Cerda, Ryuichi Shigemoto, James S. Trimmer

J Comp Neurol. Author manuscript; available in PMC 2015 Oct 15.

Published in final edited form as: J Comp Neurol. 2014 Oct 15; 522(15): 3555–3574. Published online 2014 Jul 14. doi: 10.1002/cne.23641

PMCID:: PMC4139460

Article PDF–3.0M

Select item 412371517.

High temperature sensitivity is intrinsic to voltage-gated potassium channels

Fan Yang, Jie Zheng

eLife. 2014; 3: e03255. Published online 2014 Jul 16. doi: 10.7554/eLife.03255

PMCID:: PMC4123715

Article PDF–1.7M

Select item 407760218.

Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability

David J. Speca, Genki Ogata, Danielle Mandikian, Hannah I. Bishop, Steve W. Wiler, Kenneth Eum, H. Jürgen Wenzel, Emily T. Doisy, Lucas Matt, Katharine L. Campi, Mari S. Golub, Jeanne M. Nerbonne, Johannes W. Hell, Brian C. Trainor, Jon T. Sack, Philip A. Schwartzkroin, James S. Trimmer

Genes Brain Behav. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Genes Brain Behav. 2014 Apr; 13(4): 394–408. Published online 2014 Mar 7. doi: 10.1111/gbb.12120

PMCID:: PMC4077602

Article PDF–1.4M

Select item 298851619.

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses

David A Jacobson, Felipe Mendez, Michael Thompson, Jacqueline Torres, Olivia Cochet, Louis H Philipson

J Physiol. 2010 Sep 15; 588(Pt 18): 3525–3537. Published online 2010 Jul 19. doi: 10.1113/jphysiol.2010.190207

PMCID:: PMC2988516

Article PDF–870K

Select item 269975820.

Kv2.1 Ablation Alters Glucose Induced Islet Electrical Activity, Enhancing Insulin Secretion

David A. Jacobson, Andrey Kuznetsov, James P. Lopez, Shera Kash, Carina E. Ämmälä, Louis H. Philipson

Cell Metab. Author manuscript; available in PMC 2009 Jun 22.

Published in final edited form as: Cell Metab. 2007 Sep; 6(3): 229–235. doi: 10.1016/j.cmet.2007.07.010

PMCID:: PMC2699758

Article PDF–651K

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