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Select item 96754581.

IRF4 expression by lung dendritic cells drives acute but not Trm cell–dependent memory Th2 responses

Daniel F. Camacho, Tania E. Velez, Maile K. Hollinger, Esther Wang, Chanie L. Howard, Eli P. Darnell, Domenick E. Kennedy, Paulette A. Krishack, Cara L. Hrusch, Marcus R. Clark, James J. Moon, Anne I. Sperling

JCI Insight. 2022 Nov 8; 7(21): e140384. Published online 2022 Nov 8. doi: 10.1172/jci.insight.140384

PMCID:: PMC9675458

Abstract Article PDF–4.3M

Select item 91131012.

Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4

Sho Masaki, Tomohiro Watanabe, Yasuyuki Arai, Ikue Sekai, Akane Hara, Masayuki Kurimoto, Yasuo Otsuka, Yasuhiro Masuta, Tomoe Yoshikawa, Ryutaro Takada, Ken Kamata, Kosuke Minaga, Kouhei Yamashita, Masatoshi Kudo

Clin Exp Immunol. 2022 Mar; 207(3): 340–350. Published online 2022 Jan 17. doi: 10.1093/cei/uxac005

PMCID:: PMC9113101

Abstract Article PDF–1.9M

Select item 88764613.

Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis

Kensuke Sasaki, Andrew S. Terker, Jiaqi Tang, Shirong Cao, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Stephanie R. Bennett, Ming-zhi Zhang, Raymond C. Harris

JCI Insight. 2022 Feb 22; 7(4): e150723. Published online 2022 Feb 22. doi: 10.1172/jci.insight.150723

PMCID:: PMC8876461

Abstract Article PDF–11M

Select item 86458924.

IRF4 Has a Unique Role in Early B Cell Development and Acts Prior to CD21 Expression to Control Marginal Zone B Cell Numbers

Kristina Ottens, Anne B. Satterthwaite

Front Immunol. 2021; 12: 779085. Published online 2021 Nov 22. doi: 10.3389/fimmu.2021.779085

PMCID:: PMC8645892

Abstract Article PDF–3.2M

Select item 79671415.

Deletion of Irf4 in T Cells Suppressed Autoimmune Uveitis and Dysregulated Transcriptional Programs Linked to CD4⁺ T Cell Differentiation and Metabolism

Minkyung Kang, Hyun-Su Lee, Jin Kyeong Choi, Cheng-Rong Yu, Charles E. Egwuagu

Int J Mol Sci. 2021 Mar; 22(5): 2775. Published online 2021 Mar 9. doi: 10.3390/ijms22052775

PMCID:: PMC7967141

Abstract Article PDF–2.7M

Select item 76922466.

Interferon regulatory factor 4 deficiency in CD8⁺ T cells abrogates terminal effector differentiation and promotes transplant acceptance

Dawei Zou, Jinfei Fu, Zhiyong Guo, Wenhao Chen

Immunology. 2020 Dec; 161(4): 364–379. Published online 2020 Oct 12. doi: 10.1111/imm.13258

PMCID:: PMC7692246

Abstract Article PDF–3.4M

Select item 65796237.

Myeloid Cell IRF4 signaling protects neonatal brains from hypoxic ischemic encephalopathy

Abdullah Al Mamun, Haifu Yu, Mehwish A. Mirza, Sharmeen Romana, Louise D. McCullough, Fudong Liu

Neurochem Int. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Neurochem Int. 2019 Jul; 127: 148–157. Published online 2018 Dec 23. doi: 10.1016/j.neuint.2018.12.014

PMCID:: PMC6579623

Abstract Article PDF–1.5M

Select item 54727288.

Different populations of CD11b⁺ dendritic cells drive Th2 responses in the small intestine and colon

Johannes U. Mayer, Mimoza Demiri, William W. Agace, Andrew S. MacDonald, Marcus Svensson-Frej, Simon W. Milling

Nat Commun. 2017; 8: 15820. Published online 2017 Jun 9. doi: 10.1038/ncomms15820

PMCID:: PMC5472728

Abstract Article PDF–1.1M

Select item 53505089.

Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

Bryan Vander Lugt, Jeremy Riddell, Aly A. Khan, Jason A. Hackney, Justin Lesch, Jason DeVoss, Matthew T. Weirauch, Harinder Singh, Ira Mellman

J Cell Biol. 2017 Mar 6; 216(3): 779–792. doi: 10.1083/jcb.201512012

PMCID:: PMC5350508

Abstract Article PDF–1.4M

Select item 464602410.

Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain

Soumya G. Remesh, Vishaka Santosh, Carlos R. Escalante

J Biol Chem. 2015 Nov 13; 290(46): 27779–27790. Published online 2015 Sep 24. doi: 10.1074/jbc.M115.678789

PMCID:: PMC4646024

Abstract Article PDF–3.1M

Select item 408078811.

Graded levels of IRF4 regulate CD8⁺ T cell differentiation and expansion, but not attrition, in response to acute virus infection

Ribhu Nayar, Elizabeth Schutten, Bianca Bautista, Keith Daniels, Amanda L. Prince, Megan Enos, Michael A. Brehm, Susan L. Swain, Raymond M. Welsh, Leslie J. Berg

J Immunol. Author manuscript; available in PMC 2015 Jun 15.

Published in final edited form as: J Immunol. 2014 Jun 15; 192(12): 5881–5893. Published online 2014 May 16. doi: 10.4049/jimmunol.1303187

PMCID:: PMC4080788

Abstract Article PDF–2.9M

Select item 385586312.

Interferon regulatory factor 4 sustains CD8⁺ T cell expansion and effector differentiation

Shuyu Yao, Bruno Fernando d. Buzo, Duy Pham, Li Jiang, Elizabeth J. Taparowsky, Mark H. Kaplan, Jie Sun

Immunity. Author manuscript; available in PMC 2014 Nov 14.

Published in final edited form as: Immunity. 2013 Nov 14; 39(5): 10.1016/j.immuni.2013.10.007. Published online 2013 Nov 7. doi: 10.1016/j.immuni.2013.10.007

PMCID:: PMC3855863

Abstract Article PDF–2.8M

Select item 377380113.

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8⁺ T cells

Friederike Raczkowski, Josephine Ritter, Kira Heesch, Valéa Schumacher, Anna Guralnik, Lena Höcker, Hartmann Raifer, Matthias Klein, Tobias Bopp, Hani Harb, Dörthe A. Kesper, Petra I. Pfefferle, Melanie Grusdat, Philipp A. Lang, Hans-Willi Mittrücker, Magdalena Huber

Proc Natl Acad Sci U S A. 2013 Sep 10; 110(37): 15019–15024. Published online 2013 Aug 26. doi: 10.1073/pnas.1309378110

PMCID:: PMC3773801

Abstract Article PDF–1.1M

Select item 365546414.

Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination

Sarah Bevington, Joan Boyes

EMBO J. 2013 May 15; 32(10): 1381–1392. Published online 2013 Mar 5. doi: 10.1038/emboj.2013.42

PMCID:: PMC3655464

Abstract Article PDF–1.3M

Select item 344887315.

Interferon regulatory factor 4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation

Sandra Bajaña, Kimberly Roach, Sean Turner, Jinny Paul, Susan Kovats

J Immunol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: J Immunol. 2012 Oct 1; 189(7): 3368–3377. Published online 2012 Aug 29. doi: 10.4049/jimmunol.1102613

PMCID:: PMC3448873

Abstract Article PDF–1.3M

Select item 326585916.

IRF-4 Suppresses BCR/ABL Transformation of Myeloid Cells in a DNA Binding-independent Manner

Seung-Hee Jo, Ruibao Ren

J Biol Chem. 2012 Jan 13; 287(3): 1770–1778. Published online 2011 Nov 22. doi: 10.1074/jbc.M111.289728

PMCID:: PMC3265859

Abstract Article PDF–1.8M

Select item 314869917.

IRF4 Deficiency Abrogates Lupus Nephritis Despite Enhancing Systemic Cytokine Production

Maciej Lech, Marc Weidenbusch, Onkar P. Kulkarni, Mi Ryu, Murthy Narayana Darisipudi, Heni Eka Susanti, Hans-Willi Mittruecker, Tak W. Mak, Hans-Joachim Anders

J Am Soc Nephrol. 2011 Aug; 22(8): 1443–1452. doi: 10.1681/ASN.2010121260