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Select item 45611871.

Modulation of the IL-6 Receptor α Underlies GLI2-mediated regulation of Immunoglobulin Secretion in Waldenström macroglobulinemia cells

David A. Jackson, Timothy D. Smith, Nansalmaa Amarsaikhan, Weiguo Han, Matthew S. Neil, Shannon K. Boi, Anne M. Vrabel, Ezequiel J. Tolosa, Luciana L. Almada, Martin E. Fernandez-Zapico, Sherine F. Elsawa

J Immunol. Author manuscript; available in PMC 2016 Sep 15.

Published in final edited form as: J Immunol. 2015 Sep 15; 195(6): 2908–2916. Published online 2015 Aug 3. doi: 10.4049/jimmunol.1402974

PMCID:: PMC4561187

Article PDF–1.4M

Select item 44502922.

The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity

Anna L. Furmanski, Alessandro Barbarulo, Anisha Solanki, Ching-In Lau, Hemant Sahni, Jose Ignacio Saldana, Fulvio D'Acquisto, Tessa Crompton

J Cell Sci. 2015 Jun 1; 128(11): 2085–2095. doi: 10.1242/jcs.165803

PMCID:: PMC4450292

Article

Select item 39705603.

A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity

Nicole Santos, Jeremy F. Reiter

J Cell Sci. 2014 Apr 1; 127(7): 1500–1510. doi: 10.1242/jcs.139253

PMCID:: PMC3970560

Article

Select item 39150624.

Gli protein activity is controlled by multi-site phosphorylation in vertebrate Hedgehog signaling

Pawel Niewiadomski, Jennifer H. Kong, Robert Ahrends, Yan Ma, Eric W. Humke, Sohini Khan, Mary N. Teruel, Bennett G. Novitch, Rajat Rohatgi

Cell Rep. Author manuscript; available in PMC 2015 Jan 16.

Published in final edited form as: Cell Rep. 2014 Jan 16; 6(1): 168–181. Published online 2013 Dec 27. doi: 10.1016/j.celrep.2013.12.003

PMCID:: PMC3915062

Article PDF–4.0M

Select item 35593915.

Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice

Kyu Sang Joeng, Fanxin Long

PLoS One. 2013; 8(1): e55134. Published online 2013 Jan 30. doi: 10.1371/journal.pone.0055134

PMCID:: PMC3559391

Article PDF–3.2M

Select item 82828356.

PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation

Jun Yang, Juan Wang, Yuan Liu, Yu Zhang, Wenjing Huang, Yu Zou, Yanyan Qiu, Weiyang Cai, Jing Gao, Hu Zhou, Yingli Wu, Weijun Liu, Qingqing Ding, Yanjie Zhang, Pei-hao Yin, Wenfu Tan

Cell Death Dis. 2021 Jul; 12(7): 707. Published online 2021 Jul 15. doi: 10.1038/s41419-021-03995-z

PMCID:: PMC8282835

Article PDF–3.4M

Select item 76640467.

Relative Levels of Gli1 and Gli2 Determine the Response of Ventral Neural Stem Cells to Demyelination

Daniel Z. Radecki, Heather M. Messling, James R. Haggerty-Skeans, Sai Krishna Bhamidipati, Elizabeth D. Clawson, Christian A. Overman, Madison M. Thatcher, James L. Salzer, Jayshree Samanta

Stem Cell Reports. 2020 Nov 10; 15(5): 1047–1055. Published online 2020 Oct 29. doi: 10.1016/j.stemcr.2020.10.003

PMCID:: PMC7664046

Article PDF–4.7M

Select item 67924798.

Sam68 is required for the growth and survival of nonmelanoma skin cancer

Kai Fu, Xin Sun, Xue Xia, Ryan P. Hobbs, Yajuan Guo, Pierre A. Coulombe, Fengyi Wan

Cancer Med. 2019 Oct; 8(13): 6106–6113. Published online 2019 Aug 22. doi: 10.1002/cam4.2513

PMCID:: PMC6792479

Article PDF–680K

Select item 66686759.

Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation

Eleftheria Papaioannou, Diana C. Yánez, Susan Ross, Ching-In Lau, Anisha Solanki, Mira Manilal Chawda, Alex Virasami, Ismael Ranz, Masahiro Ono, Ryan F. L. O’Shaughnessy, Tessa Crompton

J Clin Invest. 2019 Aug 1; 129(8): 3153–3170. Published online 2019 Jul 2. doi: 10.1172/JCI125170

PMCID:: PMC6668675

Article PDF–12M

Select item 637518210.

Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors

Alexandre Wojcinski, Morgane Morabito, Andrew K. Lawton, Daniel N. Stephen, Alexandra L. Joyner

Neural Dev. 2019; 14: 4. Published online 2019 Feb 14. doi: 10.1186/s13064-019-0128-y

PMCID:: PMC6375182

Article PDF–21M

Select item 539331611.

The Sonic Hedgehog-Induced Type 3 Deiodinase Facilitates Tumorigenesis of Basal Cell Carcinoma by Reducing Gli2 Inactivation

Cristina Luongo, Raffaele Ambrosio, Salvatore Salzano, Andrzej A. Dlugosz, Caterina Missero, Monica Dentice

Endocrinology. 2014 Jun; 155(6): 2077–2088. Published online 2014 Apr 2. doi: 10.1210/en.2013-2108

PMCID:: PMC5393316

Article

Select item 512556112.

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling

Alexandre N. Ermilov, Archana Kumari, Libo Li, Ariell M. Joiner, Marina A. Grachtchouk, Benjamin L. Allen, Andrzej A. Dlugosz, Charlotte M. Mistretta

PLoS Genet. 2016 Nov; 12(11): e1006442. Published online 2016 Nov 28. doi: 10.1371/journal.pgen.1006442

PMCID:: PMC5125561

Article PDF–4.5M

Select item 509668013.

Adult Gli2^+/–;Gli3^Δ699/+ Male and Female Mice Display a Spectrum of Genital Malformation

Fei He, Pedram Akbari, Rong Mo, Jennifer J. Zhang, Chi-Chung Hui, Peter C. Kim, Walid A. Farhat

PLoS One. 2016; 11(11): e0165958. Published online 2016 Nov 4. doi: 10.1371/journal.pone.0165958

PMCID:: PMC5096680

Article PDF–2.4M

Select item 439637414.

Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms

Michael Cohen, Anna Kicheva, Ana Ribeiro, Robert Blassberg, Karen M. Page, Chris P. Barnes, James Briscoe

Nat Commun. 2015 Apr 2; 6: 6709. Published online 2015 Apr 2. doi: 10.1038/ncomms7709

PMCID:: PMC4396374

Article PDF–4.0M

Select item 392974715.

The Teratogenic Effects of Prenatal Ethanol Exposure Are Exacerbated by Sonic Hedgehog or Gli2 Haploinsufficiency in the Mouse

Henry W. Kietzman, Joshua L. Everson, Kathleen K. Sulik, Robert J. Lipinski

PLoS One. 2014; 9(2): e89448. Published online 2014 Feb 19. doi: 10.1371/journal.pone.0089448

PMCID:: PMC3929747

Article PDF–309K

Select item 367507616.

Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy

Sonia Coni, Laura Antonucci, Davide D'Amico, Laura Di Magno, Paola Infante, Enrico De Smaele, Giuseppe Giannini, Lucia Di Marcotullio, Isabella Screpanti, Alberto Gulino, Gianluca Canettieri

PLoS One. 2013; 8(6): e65718. Published online 2013 Jun 6. doi: 10.1371/journal.pone.0065718