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Items: 1 to 20 of 31

1.
Control of mitochondrial function and cell growth by the atypical cadherin Fat1
Longyue L. Cao, Dario F. Riascos-Bernal, Prameladevi Chinnasamy, Charlene M. Dunaway, Rong Hou, Mario A. Pujato, Brian P. O’Rourke, Veronika Miskolci, Liang Guo, Louis Hodgson, Andras Fiser, Nicholas E. S. Sibinga
Nature. Author manuscript; available in PMC 2017 May 24.
Published in final edited form as: Nature. 2016 Nov 24; 539(7630): 575–578. Published online 2016 Nov 9. doi: 10.1038/nature20170
PMCID:
PMC5257202
ArticlePDF–5.7M
2.
n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung–Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout
Jessica Hernandez, Julia Schäffer, Christiane Herden, Fabian Johannes Pflieger, Sylvia Reiche, Svenja Körber, Hiromu Kitagawa, Joelle Welter, Susanne Michels, Carsten Culmsee, Jens Bier, Natascha Sommer, Jing X. Kang, Konstantin Mayer, Matthias Hecker, Christoph Rummel
Int J Mol Sci. 2023 Sep; 24(17): 13524. Published online 2023 Aug 31. doi: 10.3390/ijms241713524
PMCID:
PMC10487657
ArticlePDF–4.4M
3.
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes
Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Juliane Glaser, Mai H.Q. Phan, Magdalena Schindler, Daniel M. Ibrahim, Christina Paliou, Andrea Esposito, Cesar A. Prada-Medina, Stefan A. Haas, Peter Giere, Martin Vingron, Lars Wittler, Alexander Meissner, Mario Nicodemi, Giacomo Cavalli, Frédéric Bantignies, Stefan Mundlos, Michael I. Robson
Cell. 2022 Sep 29; 185(20): 3689–3704.e21. doi: 10.1016/j.cell.2022.09.006
PMCID:
PMC9567273
ArticlePDF–11M
4.
The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals
Rong Hou, Liming Liu, Syed Anees, Shungo Hiroyasu, Nicholas E.S. Sibinga
J Cell Biol. 2006 May 8; 173(3): 417–429. doi: 10.1083/jcb.200508121
PMCID:
PMC2063842
ArticlePDF–7.8M
5.
Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2
Rui Li, Jingchen Shao, Young-June Jin, Haruya Kawase, Yu Ting Ong, Kerstin Troidl, Qi Quan, Lei Wang, Remy Bonnavion, Astrid Wietelmann, Francoise Helmbacher, Michael Potente, Johannes Graumann, Nina Wettschureck, Stefan Offermanns
Nat Commun. 2023; 14: 1980. Published online 2023 Apr 8. doi: 10.1038/s41467-023-37671-x
PMCID:
PMC10082778
ArticlePDF–4.0M
6.
Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism
Jeannine A. Frei, Cheryl J. Brandenburg, Jonathan E. Nestor, Didier M. Hodzic, Celine Plachez, Helen McNeill, Derek M. Dykxhoorn, Michael W. Nestor, Gene J. Blatt, Yu-Chih Lin
Biol Open. 2021 Jun 15; 10(6): bio056457. Published online 2021 Jun 8. doi: 10.1242/bio.056457
PMCID:
PMC8214424
ArticlePDF–1.7M
7.
Capturing genes encoding membrane and secreted proteins important for mouse development.
W C Skarnes, J E Moss, S M Hurtley, R S Beddington
Proc Natl Acad Sci U S A. 1995 Jul 3; 92(14): 6592–6596. doi: 10.1073/pnas.92.14.6592
PMCID:
PMC41564
SummaryPage BrowsePDF–1.8M
8.
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
Ievgenia Pastushenko, Federico Mauri, Yura Song, Florian de Cock, Bob Meeusen, Benjamin Swedlund, Francis Impens, Delphi Van Haver, Matthieu Opitz, Manuel Thery, Yacine Bareche, Gaelle Lapouge, Marjorie Vermeersch, Yves-Rémi Van Eycke, Cédric Balsat, Christine Decaestecker, Youri Sokolow, Sergio Hassid, Alicia Perez-Bustillo, Beatriz Agreda-Moreno, Luis Rios-Buceta, Pedro Jaen, Pedro Redondo, Ramon Sieira-Gil, Jose F. Millan-Cayetano, Onofre Sanmatrtin, Nicky D’Haene, Virginie Moers, Milena Rozzi, Jeremy Blondeau, Sophie Lemaire, Samuel Scozzaro, Veerle Janssens, Magdalena De Troya, Christine Dubois, David Pérez-Morga, Isabelle Salmon, Christos Sotiriou, Francoise Helmbacher, Cédric Blanpain
Nature. Author manuscript; available in PMC 2022 Feb 28.
Published in final edited form as: Nature. 2021 Jan 1; 589(7842): 448–455. Published online 2020 Dec 16. doi: 10.1038/s41586-020-03046-1
PMCID:
PMC7612440
ArticlePDF–7.8M
9.
Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity
Sakura Saburi, Ian Hester, Lisa Goodrich, Helen McNeill
Development. 2012 May 15; 139(10): 1806–1820. doi: 10.1242/dev.077461
PMCID:
PMC3328180
Article
10.
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly
Najim Lahrouchi, Aman George, Ilham Ratbi, Ronen Schneider, Siham C. Elalaoui, Shahida Moosa, Sanita Bharti, Ruchi Sharma, Mones Abu-Asab, Felix Onojafe, Najlae Adadi, Elisabeth M. Lodder, Fatima-Zahra Laarabi, Yassine Lamsyah, Hamza Elorch, Imane Chebbar, Alex V. Postma, Vassilios Lougaris, Alessandro Plebani, Janine Altmueller, Henriette Kyrieleis, Vardiella Meiner, Helen McNeill, Kapil Bharti, Stanislas Lyonnet, Bernd Wollnik, Alexandra Henrion-Caude, Amina Berraho, Friedhelm Hildebrandt, Connie R. Bezzina, Brian P. Brooks, Abdelaziz Sefiani
Nat Commun. 2019; 10: 1180. Published online 2019 Mar 12. doi: 10.1038/s41467-019-08547-w
PMCID:
PMC6414540
ArticlePDF–2.3M
11.
Atrophin Proteins Interact with the Fat1 Cadherin and Regulate Migration and Orientation in Vascular Smooth Muscle Cells
Rong Hou, Nicholas E. S. Sibinga
J Biol Chem. 2009 Mar 13; 284(11): 6955–6965. doi: 10.1074/jbc.M809333200
PMCID:
PMC2652288
ArticlePDF–1.2M
12.
FAT1 mutations cause a glomerulotubular nephropathy
Heon Yung Gee, Carolin E. Sadowski, Pardeep K. Aggarwal, Jonathan D. Porath, Toma A. Yakulov, Markus Schueler, Svjetlana Lovric, Shazia Ashraf, Daniela A. Braun, Jan Halbritter, Humphrey Fang, Rannar Airik, Virginia Vega-Warner, Kyeong Jee Cho, Timothy A. Chan, Luc G. T. Morris, Charles ffrench-Constant, Nicholas Allen, Helen McNeill, Rainer Büscher, Henriette Kyrieleis, Michael Wallot, Ariana Gaspert, Thomas Kistler, David V. Milford, Moin A. Saleem, Wee Teik Keng, Stephen I. Alexander, Rudolph P. Valentini, Christoph Licht, Jun C. Teh, Radovan Bogdanovic, Ania Koziell, Agnieszka Bierzynska, Neveen A. Soliman, Edgar A. Otto, Richard P. Lifton, Lawrence B. Holzman, Nicholas E. S. Sibinga, Gerd Walz, Alda Tufro, Friedhelm Hildebrandt
Nat Commun. 2016; 7: 10822. Published online 2016 Feb 24. doi: 10.1038/ncomms10822
PMCID:
PMC4770090
ArticlePDF–1.4M
13.
Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy
Nathalie Caruso, Balàzs Herberth, Marc Bartoli, Francesca Puppo, Julie Dumonceaux, Angela Zimmermann, Simon Denadai, Marie Lebossé, Stephane Roche, Linda Geng, Frederique Magdinier, Shahram Attarian, Rafaelle Bernard, Flavio Maina, Nicolas Levy, Françoise Helmbacher
PLoS Genet. 2013 Jun; 9(6): e1003550. Published online 2013 Jun 13. doi: 10.1371/journal.pgen.1003550
PMCID:
PMC3681729
ArticlePDF–18M
14.
Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation
Yuki Sugiyama, Elizabeth J. Shelley, Caroline Badouel, Helen McNeill, John W. McAvoy
Invest Ophthalmol Vis Sci. 2015 Jun; 56(6): 4099–4107. Published online 2015 Jun 24. doi: 10.1167/iovs.15-17008
PMCID:
PMC4484397
ArticlePDF–1.6M
15.
Mice Lacking the Giant Protocadherin mFAT1 Exhibit Renal Slit Junction Abnormalities and a Partially Penetrant Cyclopia and Anophthalmia Phenotype
Lorenza Ciani, Anjla Patel, Nicholas D. Allen, Charles ffrench-Constant
Mol Cell Biol. 2003 May; 23(10): 3575–3582. doi: 10.1128/MCB.23.10.3575-3582.2003
PMCID:
PMC164754
ArticlePDF–549K
16.
Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development
Caroline Badouel, Mark A. Zander, Nicole Liscio, Mazdak Bagherie-Lachidan, Richelle Sopko, Etienne Coyaud, Brian Raught, Freda D. Miller, Helen McNeill
Development. 2015 Aug 15; 142(16): 2781–2791. doi: 10.1242/dev.123539
PMCID:
PMC4550967
Article
17.
Mammalian Fat1 cadherin regulates actin dynamics and cell–cell contact
Takuji Tanoue, Masatoshi Takeichi
J Cell Biol. 2004 May 24; 165(4): 517–528. doi: 10.1083/jcb.200403006
PMCID:
PMC2172355
ArticlePDF–3.1M
18.
Tissue-specific activities of the Fat1 cadherin cooperate to control neuromuscular morphogenesis
Françoise Helmbacher
PLoS Biol. 2018 May; 16(5): e2004734. Published online 2018 May 16. doi: 10.1371/journal.pbio.2004734
PMCID:
PMC5973635
ArticlePDF–44M
19.
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes
Markus M. Rinschen, Puneet Bharill, Xiongwu Wu, Priyanka Kohli, Matthäus J. Reinert, Oliver Kretz, Isabel Saez, Bernhard Schermer, Martin Höhne, Malte P. Bartram, Sriram Aravamudhan, Bernard R. Brooks, David Vilchez, Tobias B. Huber, Roman-Ulrich Müller, Marcus Krüger, Thomas Benzing
Hum Mol Genet. 2016 Apr 1; 25(7): 1328–1344. Published online 2016 Jan 19. doi: 10.1093/hmg/ddw016
PMCID:
PMC4787903
ArticlePDF–1.0M
20.
Comparative Genomics and Diversifying Selection of the Clustered Vertebrate Protocadherin Genes
Qiang Wu
Genetics. 2005 Apr; 169(4): 2179–2188. doi: 10.1534/genetics.104.037606
PMCID:
PMC1449604
ArticlePDF–562K

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