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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 83963482.

Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1

Georgios Galaris, Kévin Montagne, Jérémy H. Thalgott, Geoffroy J. P. E. Goujon, Sander van den Driesche, Sabrina Martin, Hans-Jurgen J. Mager, Christine L. Mummery, Ton J. Rabelink, Franck Lebrin

Int J Mol Sci. 2021 Aug; 22(16): 8948. Published online 2021 Aug 19. doi: 10.3390/ijms22168948

PMCID:: PMC8396348

Article PDF–11M

Select item 79226013.

BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice

Wineke Bakker, Calinda K. E. Dingenouts, Kirsten Lodder, Karien C. Wiesmeijer, Alwin de Jong, Kondababu Kurakula, Hans-Jurgen J. Mager, Anke M. Smits, Margreet R. de Vries, Paul H. A. Quax, Marie José T. H. Goumans

Int J Mol Sci. 2021 Feb; 22(4): 2010. Published online 2021 Feb 18. doi: 10.3390/ijms22042010

PMCID:: PMC7922601

Article PDF–4.7M

Select item 77310454.

Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver

Ivone Cristina Igreja Sá, Katarina Tripska, Milos Hroch, Radomir Hyspler, Alena Ticha, Hana Lastuvkova, Jolana Schreiberova, Eva Dolezelova, Samira Eissazadeh, Barbora Vitverova, Iveta Najmanova, Martina Vasinova, Miguel Pericacho, Stanislav Micuda, Petr Nachtigal

Int J Mol Sci. 2020 Dec; 21(23): 9021. Published online 2020 Nov 27. doi: 10.3390/ijms21239021

PMCID:: PMC7731045

Article PDF–4.0M

Select item 75248315.

Arterial endoglin does not protect against arteriovenous malformations

Esha Singh, Rachael E. Redgrave, Helen M. Phillips, Helen M. Arthur

Angiogenesis. 2020; 23(4): 559–566. Published online 2020 Jun 6. doi: 10.1007/s10456-020-09731-z

PMCID:: PMC7524831

Article PDF–2.6M

Select item 71600776.

Continuous endoglin (CD105) overexpression disrupts angiogenesis and facilitates tumor cell metastasis

Claudia Ollauri-Ibáñez, Elena Núñez-Gómez, Cristina Egido-Turrión, Laura Silva-Sousa, Elena Díaz-Rodríguez, Alicia Rodríguez-Barbero, José M. López-Novoa, Miguel Pericacho

Angiogenesis. 2020; 23(2): 231–247. Published online 2020 Jan 3. doi: 10.1007/s10456-019-09703-y

PMCID:: PMC7160077

Article PDF–3.3M

Select item 70332227.

S-endoglin expression is induced in hyperoxia and contributes to altered pulmonary angiogenesis in bronchopulmonary dysplasia development

Yeongseok Lee, Juyoung Lee, Soo Kyung Nam, Yong Hoon Jun

Sci Rep. 2020; 10: 3043. Published online 2020 Feb 20. doi: 10.1038/s41598-020-59928-x

PMCID:: PMC7033222

Article PDF–6.1M

Select item 63599248.

A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

María I Calvo-Sánchez, Sandra Fernández-Martos, Elisa Carrasco, Gema Moreno-Bueno, Carmelo Bernabéu, Miguel Quintanilla, Jesús Espada

J Mol Cell Biol. 2019 Jan; 11(1): 39–52. Published online 2018 Sep 18. doi: 10.1093/jmcb/mjy051

PMCID:: PMC6359924

Article PDF–1.6M

Select item 56906829.

Circulating soluble endoglin modifies the inflammatory response in mice

Laura Ruiz-Remolina, Claudia Ollauri-Ibáñez, Lucía Pérez-Roque, Elena Núñez-Gómez, Fernando Pérez-Barriocanal, José Miguel López-Novoa, Miguel Pericacho, Alicia Rodríguez-Barbero

PLoS One. 2017; 12(11): e0188204. Published online 2017 Nov 16. doi: 10.1371/journal.pone.0188204

PMCID:: PMC5690682

Article PDF–7.1M

Select item 506471610.

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Rabab Nasrallah, Eva M. Fast, Parham Solaimani, Kathy Knezevic, Alexia Eliades, Rahima Patel, Roshana Thambyrajah, Ashwin Unnikrishnan, Julie Thoms, Dominik Beck, Chris S. Vink, Aileen Smith, Jason Wong, Mairi Shepherd, David Kent, Rahul Roychoudhuri, Fabian Paul, Julia Klippert, Annette Hammes, Thomas Willnow, Bertie Göttgens, Elaine Dzierzak, Leonard I. Zon, George Lacaud, Valerie Kouskoff, John E. Pimanda

Blood. 2016 Oct 13; 128(15): 1928–1939. Prepublished online 2016 Aug 23. doi: 10.1182/blood-2016-02-697870

Correction in:: Blood. 2017 Nov 16; 130(20): 2234.

PMCID:: PMC5064716

Article

Select item 477453311.

Reduced Endoglin Activity Limits Cardiac Fibrosis and Improves Survival in Heart Failure

Navin K. Kapur, Szuhuei Wilson, Adil A. Yunis, Xiaoying Qiao, Emily Mackey, Vikram Paruchuri, Corey Baker, Mark J. Aronovitz, S. Ananth Karumanchi, Michelle Letarte, David A. Kass, Michael E. Mendelsohn, Richard H. Karas

Circulation. Author manuscript; available in PMC 2016 Mar 2.

Published in final edited form as: Circulation. 2012 Jun 5; 125(22): 2728–2738. Published online 2012 May 16. doi: 10.1161/CIRCULATIONAHA.111.080002

PMCID:: PMC4774533

Article PDF–2.8M

Select item 435356712.

Facilitation of endoglin-targeting cancer therapy by development/utilization of a novel genetically engineered mouse model expressing humanized endoglin (CD105)

Hirofumi Toi, Masanori Tsujie, Yuro Haruta, Kanako Fujita, Jill Duzen, Ben K. Seon

Int J Cancer. Author manuscript; available in PMC 2016 Jan 15.

Published in final edited form as: Int J Cancer. 2015 Jan 15; 136(2): 452–461. Published online 2014 Jun 13. doi: 10.1002/ijc.28994

PMCID:: PMC4353567

Article PDF–1.4M

Select item 412119213.

Impaired Resolution of Inflammation in the Endoglin Heterozygous Mouse Model of Chronic Colitis

Madonna R. Peter, Mirjana Jerkic, Valentin Sotov, David N. Douda, Daniela S. Ardelean, Niousha Ghamami, Flavia Lakschevitz, Meraj A. Khan, Susan J. Robertson, Michael Glogauer, Dana J. Philpott, Nades Palaniyar, Michelle Letarte

Mediators Inflamm. 2014; 2014: 767185. Published online 2014 Jul 10. doi: 10.1155/2014/767185

PMCID:: PMC4121192

Article PDF–2.5M

Select item 390488114.

ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis

Zhen Liu, Franck Lebrin, Janita A. Maring, Sander van den Driesche, Stieneke van der Brink, Maarten van Dinther, Midory Thorikay, Sabrina Martin, Kazuki Kobayashi, Lukas J. A. C. Hawinkels, Laurens A. van Meeteren, Evangelia Pardali, Jeroen Korving, Michelle Letarte, Helen M. Arthur, Charles Theuer, Marie-José Goumans, Christine Mummery, Peter ten Dijke

PLoS One. 2014; 9(1): e86273. Published online 2014 Jan 28. doi: 10.1371/journal.pone.0086273

PMCID:: PMC3904881

Article PDF–3.1M

Select item 379074015.

CD105 (Endoglin)-Negative Murine Mesenchymal Stromal Cells Define a New Multipotent Subpopulation with Distinct Differentiation and Immunomodulatory Capacities

Per Anderson, Ana Belén Carrillo-Gálvez, Angélica García-Pérez, Marién Cobo, Francisco Martín

PLoS One. 2013; 8(10): e76979. Published online 2013 Oct 4. doi: 10.1371/journal.pone.0076979

PMCID:: PMC3790740

Article PDF–1.3M

Select item 372220716.

Endoglin Haplo-Insufficiency Modifies the Inflammatory Response in Irradiated Mouse Hearts without Affecting Structural and Mircovascular Changes

Ingar Seemann, Johannes A. M. te Poele, Sophia J. Luikinga, Saske Hoving, Fiona A. Stewart

PLoS One. 2013; 8(7): e68922. Published online 2013 Jul 24. doi: 10.1371/journal.pone.0068922

PMCID:: PMC3722207

Article PDF–1.9M

Select item 364414017.

Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways

SunYoung Park, Terri A. DiMaio, Wei Liu, Shoujian Wang, Christine M. Sorenson, Nader Sheibani

J Cell Sci. 2013 Mar 15; 126(6): 1392–1405. doi: 10.1242/jcs.117275

PMCID:: PMC3644140

Article

Select item 360089918.

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

Charlotte Anderberg, Sara I. Cunha, Zhenhua Zhai, Eliane Cortez, Evangelia Pardali, Jill R. Johnson, Marcela Franco, Marta Páez-Ribes, Ross Cordiner, Jonas Fuxe, Bengt R. Johansson, Marie-José Goumans, Oriol Casanovas, Peter ten Dijke, Helen M. Arthur, Kristian Pietras

J Exp Med. 2013 Mar 11; 210(3): 563–579. doi: 10.1084/jem.20120662

PMCID:: PMC3600899

Article PDF–4.0M

Select item 354595919.

Heterozygous Deficiency of Endoglin Decreases Insulin and Hepatic Triglyceride Levels during High Fat Diet

Daniel Beiroa, Amparo Romero-Picó, Carmen Langa, Carmelo Bernabeu, Miguel López, José M. López-Novoa, Ruben Nogueiras, Carlos Diéguez

PLoS One. 2013; 8(1): e54591. Published online 2013 Jan 15. doi: 10.1371/journal.pone.0054591

PMCID:: PMC3545959

Article PDF–806K

Select item 344711320.

EFFECT OF ENDOGLIN OVEREXPRESSION DURING EMBRYOID BODY DEVELOPMENT

June Baik, Luciene Borges, Alessandro Magli, Tayaramma Thatava, Rita C. R. Perlingeiro

Exp Hematol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Exp Hematol. 2012 Oct; 40(10): 837–846. Published online 2012 Jun 19. doi: 10.1016/j.exphem.2012.06.007

PMCID:: PMC3447113

Article PDF–1.9M

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