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Items: 1 to 20 of 26

1.
Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function
Crystal M Vander Zanden, Ryan S Czarny, Ethan N Ho, Adam B Robertson, P Shing Ho
Nucleic Acids Res. 2020 Apr 17; 48(7): 3962–3974. Published online 2020 Feb 25. doi: 10.1093/nar/gkaa117
PMCID:
PMC7144941
ArticlePDF–4.8M
2.
Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin
Natividad Blasco, Yolanda Cámara, Estefanía Núñez, Aida Beà, Gisel Barés, Carles Forné, Marisol Ruíz-Meana, Cristina Girón, Ignasi Barba, Elena García-Arumí, David García-Dorado, Jesús Vázquez, Ramon Martí, Marta Llovera, Daniel Sanchis
Redox Biol. 2018 Jun; 16: 146–156. Published online 2018 Mar 1. doi: 10.1016/j.redox.2018.02.021
PMCID:
PMC5952880
ArticlePDF–1.0M
3.
Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions
Hong Zan, Jinsong Zhang, Ahmed Al-Qahtani, Egest J. Pone, Clayton A. White, Derrik Lee, Leman Yel, Thach Mai, Paolo Casali
Mol Immunol. Author manuscript; available in PMC 2012 Aug 5.
Published in final edited form as: Mol Immunol. 2011 Jan; 48(4): 610–622. Published online 2010 Nov 26. doi: 10.1016/j.molimm.2010.10.023
PMCID:
PMC3412130
ArticlePDF–4.8M
4.
Endonuclease G mediates endothelial cell death induced by carbamylated LDL
Eugene O. Apostolov, Debarti Ray, Wilson M. Alobuia, Marina V. Mikhailova, Xiaoying Wang, Alexei G. Basnakian, Sudhir V. Shah
Am J Physiol Heart Circ Physiol. 2011 Jun; 300(6): H1997–H2004. Published online 2011 Apr 1. doi: 10.1152/ajpheart.01311.2010
PMCID:
PMC3119093
Article
5.
Purification, crystallization and data collection of the apoptotic nuclease endonuclease G
Sei Mee Yoon, Hyung Nam Song, Jun Hyuk Yang, Mi Yeon Lim, Yong Je Chung, Seong Eon Ryu, Eui Jeon Woo
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1; 65(Pt 5): 504–507. Published online 2009 Apr 24. doi: 10.1107/S1744309109013335
PMCID:
PMC2675596
ArticlePDF–159K
6.
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Adam B. Robertson, Julia Robertson, Markus Fusser, Arne Klungland
Nucleic Acids Res. 2014 Dec 1; 42(21): 13280–13293. Published online 2014 Oct 29. doi: 10.1093/nar/gku1032
PMCID:
PMC4245937
ArticlePDF–546K
7.
Uptake of Foreign Nucleic Acids in Kidney Tubular Epithelial Cells Deficient in Proapoptotic Endonucleases
Timea Buzder, Xiaoyan Yin, Xiaoying Wang, Gaspar Banfalvi, Alexei G. Basnakian
DNA Cell Biol. 2009 Sep; 28(9): 435–442. doi: 10.1089/dna.2008.0850
PMCID:
PMC2903456
ArticlePDF–221K
8.
Generation and Characterization of Endonuclease G Null Mice
Ryan A. Irvine, Noritaka Adachi, Darryl K. Shibata, Geoffrey D. Cassell, Kefei Yu, Zarir E. Karanjawala, Chih-Lin Hsieh, Michael R. Lieber
Mol Cell Biol. 2005 Jan; 25(1): 294–302. doi: 10.1128/MCB.25.1.294-302.2005
PMCID:
PMC538798
ArticlePDF–271K
9.
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function
Chris McDermott-Roe, Junmei Ye, Rizwan Ahmed, Xi-Ming Sun, Anna Serafín, James Ware, Leonardo Bottolo, Phil Muckett, Xavier Cañas, Jisheng Zhang, Glenn C. Rowe, Rachel Buchan, Han Lu, Adam Braithwaite, Massimiliano Mancini, David Hauton, Ramon Martí, Elena García-Arumí, Norbert Hubner, Howard Jacob, Tadao Serikawa, Vaclav Zidek, Frantisek Papousek, Frantisek Kolar, Maria Cardona, Marisol Ruiz-Meana, David García-Dorado, Joan X Comella, Leanne E Felkin, Paul JR Barton, Zoltan Arany, Michal Pravenec, Enrico Petretto, Daniel Sanchis, Stuart A. Cook
Nature. Author manuscript; available in PMC 2012 Apr 5.
Published in final edited form as: Nature. 2011 Oct 5; 478(7367): 114–118. Published online 2011 Oct 5. doi: 10.1038/nature10490
PMCID:
PMC3189541
ArticlePDF–1.7M
10.
Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress
Wenjun Wang, Junyang Tan, Xiaomin Liu, Wenqi Guo, Mengmeng Li, Xinjie Liu, Yanyan Liu, Wenyu Dai, Liubing Hu, Yimin Wang, Qiuxia Lu, Wen Xing Lee, Hong-Wen Tang, Qinghua Zhou
Nat Commun. 2023; 14: 6201. Published online 2023 Oct 4. doi: 10.1038/s41467-023-41757-x
PMCID:
PMC10550995
ArticlePDF–3.2M
11.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response
Wenjun Wang, Jianshuang Li, Junyang Tan, Miaomiao Wang, Jing Yang, Zhi-Min Zhang, Chuanzhou Li, Alexei G. Basnakian, Hong-Wen Tang, Norbert Perrimon, Qinghua Zhou
Nat Commun. 2021; 12: 476. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20780-2
PMCID:
PMC7817833
ArticlePDF–6.3M
12.
Endonuclease G is required for early embryogenesis and normal apoptosis in mice
Jianhua Zhang, Mei Dong, Lily Li, Yunxia Fan, Purnima Pathre, Jin Dong, Danwen Lou, James M. Wells, Danyvid Olivares-Villagómez, Luc Van Kaer, Xiaodong Wang, Ming Xu
Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26): 15782–15787. Published online 2003 Dec 8. doi: 10.1073/pnas.2636393100
PMCID:
PMC307645
ArticlePDF–448K
13.
IGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins
Ning Dai, Liping Zhao, Diedra Wrighting, Dana Krämer, Amit Majithia, Yanqun Wang, Valentin Cracan, Diego Borges-Rivera, Vamsi K. Mootha, Matthias Nahrendorf, David R. Thorburn, Liliana Minichiello, David Altshuler, Joseph Avruch
Cell Metab. Author manuscript; available in PMC 2016 Apr 7.
Published in final edited form as: Cell Metab. 2015 Apr 7; 21(4): 609–621. doi: 10.1016/j.cmet.2015.03.006
PMCID:
PMC4663978
ArticlePDF–2.9M
14.
No death without life: vital functions of apoptotic effectors
L Galluzzi, N Joza, E Tasdemir, MC Maiuri, M Hengartner, JM Abrams, N Tavernarakis, J Penninger, F Madeo, G Kroemer
Cell Death Differ. Author manuscript; available in PMC 2010 Aug 9.
Published in final edited form as: Cell Death Differ. 2008 Jul; 15(7): 1113–1123. Published online 2008 Feb 29. doi: 10.1038/cdd.2008.28
PMCID:
PMC2917777
ArticlePDF–347K
15.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
ArticlePDF–3.0M
16.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
ArticlePDF–1.2M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
ArticlePDF–5.7M
18.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
19.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
20.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M

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