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Select item 109127691.

A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

Ziad Jowhar, Albert Xu, Srivats Venkataramanan, Francesco Dossena, Mariah L Hoye, Debra L Silver, Stephen N Floor, Lorenzo Calviello

Mol Syst Biol. 2024 Mar; 20(3): 276–290. Published online 2024 Jan 25. doi: 10.1038/s44320-024-00013-0

PMCID:: PMC10912769

Article PDF–3.8M

Select item 103228692.

Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress

Tingting Luo, Suzhen Yang, Tianming Zhao, Hanlong Zhu, Chunyan Chen, Xiaoxiao Shi, Di Chen, Kai Wang, Kang Jiang, Dan Xu, Ming Cheng, Juan Li, Wenting Li, Weijun Xu, Lin Zhou, Mingzuo Jiang, Bing Xu

Cell Death Dis. 2023 Jul; 14(7): 400. Published online 2023 Jul 6. doi: 10.1038/s41419-023-05913-x

PMCID:: PMC10322869

Article PDF–4.9M

Select item 67055633.

DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation

Hung-Hsi Chen, Hsin-I Yu, Woan-Yuh Tarn

J Neurosci. 2016 Sep 21; 36(38): 9792–9804. doi: 10.1523/JNEUROSCI.4603-15.2016

PMCID:: PMC6705563

Article PDF–4.2M

Select item 107345504.

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Nikhil Sharma, Patricia Kessler, Ganes C. Sen

J Virol. 2023 Dec; 97(12): e01304-23. Published online 2023 Nov 20. doi: 10.1128/jvi.01304-23

PMCID:: PMC10734550

Article PDF–913K

Select item 104336305.

miR-181a-5p targets DDX3X to inhibit the progression of osteoarthritis via NF-ΚB signaling pathway

Peng Zhao, Guobin Ma, Lintong Ma

J Orthop Surg Res. 2023; 18: 606. Published online 2023 Aug 16. doi: 10.1186/s13018-023-04073-0

PMCID:: PMC10433630

Article PDF–2.0M

Select item 85710436.

Developmental and behavioral phenotypes in a mouse model of DDX3X syndrome

Andrea Boitnott, Marta Garcia-Forn, Dévina C Ung, Kristi Niblo, Danielle Mendonca, Yeaji Park, Michael Flores, Sylvia Maxwell, Jacob Ellegood, Lily R Qiu, Dorothy E Grice, Jason P Lerch, Mladen-Roko Rasin, Joseph D Buxbaum, Elodie Drapeau, Silvia De Rubeis

Biol Psychiatry. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Biol Psychiatry. 2021 Dec 1; 90(11): 742–755. Published online 2021 Jun 7. doi: 10.1016/j.biopsych.2021.05.027

PMCID:: PMC8571043

Article PDF–2.1M

Select item 82105967.

Demalonylation of DDX3 by Sirtuin 5 promotes antiviral innate immune responses

Xingying He, Tianliang Li, Kewei Qin, Shiyuan Luo, Zhenjie Li, Qingqing Ji, Honghao Song, Huyang He, Hao Tang, Chaofeng Han, Hongjiao Li, Yan Luo

Theranostics. 2021; 11(15): 7235–7246. Published online 2021 May 24. doi: 10.7150/thno.52934

PMCID:: PMC8210596

Article PDF–1.7M

Select item 80819178.

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

Sannula Kesavardhana, Parimal Samir, Min Zheng, R.K. Subbarao Malireddi, Rajendra Karki, Bhesh Raj Sharma, David E. Place, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti

J Biol Chem. 2021 Jan-Jun; 296: 100579. Published online 2021 Mar 23. doi: 10.1016/j.jbc.2021.100579

PMCID:: PMC8081917

Article PDF–2.6M

Select item 64731069.

An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility

Takafumi MATSUMURA, Tsutomu ENDO, Ayako ISOTANI, Masaki OGAWA, Masahito IKAWA

J Reprod Dev. 2019 Apr; 65(2): 121–128. Published online 2019 Jan 7. doi: 10.1262/jrd.2018-145

PMCID:: PMC6473106

Article PDF–3.7M

Select item 628361610.

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity

Daniel Szappanos, Roland Tschismarov, Thomas Perlot, Sandra Westermayer, Katrin Fischer, Ekaterini Platanitis, Fabian Kallinger, Maria Novatchkova, Caroline Lassnig, Mathias Müller, Veronika Sexl, Keiryn L. Bennett, Michelle Foong-Sobis, Josef M. Penninger, Thomas Decker

PLoS Pathog. 2018 Nov; 14(11): e1007397. Published online 2018 Nov 26. doi: 10.1371/journal.ppat.1007397

PMCID:: PMC6283616

Article PDF–4.1M

Select item 219320111.

An N-Acetylated Natural Ligand of Human Histocompatibility Leukocyte Antigen (Hla)-B39: Classical Major Histocompatibility Complex Class I Proteins Bind Peptides with a Blocked Nh₂ Terminus in Vivo

Jesús Yagüe, Iñaki Alvarez, Didier Rognan, Manuel Ramos, Jesús Vázquez, José A. López de Castro

J Exp Med. 2000 Jun 19; 191(12): 2083–2092. doi: 10.1084/jem.191.12.2083

PMCID:: PMC2193201

Article PDF–147K

Select item 113680012.

The embryonic RNA helicase gene (ERH): a new member of the DEAD box family of RNA helicases.

J Sowden, W Putt, K Morrison, R Beddington, Y Edwards

Biochem J. 1995 Jun 15; 308(Pt 3): 839–846. doi: 10.1042/bj3080839

PMCID:: PMC1136800

Summary Page Browse PDF–3.3M

Select item 567488213.

lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy

Ronald L Neppl, Chia-Ling Wu, Kenneth Walsh

J Cell Biol. 2017 Nov 6; 216(11): 3497–3507. doi: 10.1083/jcb.201612100

PMCID:: PMC5674882

Article PDF–1.8M

Select item 808605514.

Galactosaminogalactan activates the inflammasome to provide host protection

Benoit Briard, Thierry Fontaine, Parimal Samir, David E. Place, Laetitia Muszkieta, R.K. Subbarao Malireddi, Rajendra Karki, Shelbi Christgen, Perrine Bomme, Peter Vogel, Rémi Beau, Emilia Mellado, Oumaima Ibrahim-Granet, Bernard Henrissat, Ravi C Kalathur, Cam Robinson, Jean-Paul Latgé, Thirumala-Devi Kanneganti

Nature. Author manuscript; available in PMC 2021 Jun 2.

Published in final edited form as: Nature. 2020 Dec; 588(7839): 688–692. Published online 2020 Dec 2. doi: 10.1038/s41586-020-2996-z

Correction in:: Nature. 2020 Dec 21

PMCID:: PMC8086055

Article PDF–4.4M

Select item 733128515.

Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development

Ashley L. Lennox, Mariah L. Hoye, Ruiji Jiang, Bethany L. Johnson-Kerner, Lindsey A. Suit, Srivats Venkataramanan, Charles J. Sheehan, Fernando C. Alsina, Brieana Fregeau, Kimberly A. Aldinger, Ching Moey, Iryna Lobach, Alexandra Afenjar, Dusica Babovic-Vuksanovic, Stéphane Bézieau, Patrick R. Blackburn, Jens Bunt, Lydie Burglen, Philippe M. Campeau, Perrine Charles, Brian H.Y. Chung, Benjamin Cogné, Cynthia Curry, Maria Daniela D’Agostino, Nataliya Di Donato, Laurence Faivre, Delphine Héron, A. Micheil Innes, Bertrand Isidor, Boris Keren, Amy Kimball, Eric W. Klee, Paul Kuentz, Sébastien Küry, Dominique Martin-Coignard, Ghayda Mirzaa, Cyril Mignot, Noriko Miyake, Naomichi Matsumoto, Atsushi Fujita, Caroline Nava, Mathilde Nizon, Diana Rodriguez, Lot Snijders Blok, Christel Thauvin-Robinet, Julien Thevenon, Marie Vincent, Alban Ziegler, William Dobyns, Linda J. Richards, A. James Barkovich, Stephen N. Floor, Debra L. Silver, Elliott H. Sherr

Neuron. Author manuscript; available in PMC 2021 May 6.

Published in final edited form as: Neuron. 2020 May 6; 106(3): 404–420.e8. Published online 2020 Mar 4. doi: 10.1016/j.neuron.2020.01.042

PMCID:: PMC7331285

Article PDF–3.2M

Select item 698028416.

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

Parimal Samir, Sannula Kesavardhana, Deanna M. Patmore, Sebastien Gingras, R. K. Subbarao Malireddi, Rajendra Karki, Clifford S. Guy, Benoit Briard, David E. Place, Anannya Bhattacharya, Bhesh raj Sharma, Amanda Nourse, Sharon V. King, Aaron Pitre, Amanda R. Burton, Stephane Pelletier, Richard J. Gilbertson, Thirumala-Devi Kanneganti

Nature. Author manuscript; available in PMC 2020 Mar 11.

Published in final edited form as: Nature. 2019 Sep; 573(7775): 590–594. Published online 2019 Sep 11. doi: 10.1038/s41586-019-1551-2

PMCID:: PMC6980284

Article PDF–5.6M

Select item 245305917.

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

Didier Soulat, Tilmann Bürckstümmer, Sandra Westermayer, Adriana Goncalves, Angela Bauch, Adrijana Stefanovic, Oliver Hantschel, Keiryn L Bennett, Thomas Decker, Giulio Superti-Furga

EMBO J. 2008 Aug 6; 27(15): 2135–2146. Published online 2008 Jun 26. doi: 10.1038/emboj.2008.126

PMCID:: PMC2453059

Article PDF–484K

Select item 446890718.

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture

Jacek Krol, Ilona Krol, Claudia Patricia Patino Alvarez, Michele Fiscella, Andreas Hierlemann, Botond Roska, Witold Filipowicz

Nat Commun. 2015; 6: 7305. Published online 2015 Jun 4. doi: 10.1038/ncomms8305

PMCID:: PMC4468907

Article PDF–2.9M

Select item 556106019.

Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems

Kathy Ushakov, Tal Koffler-Brill, Aviv Rom, Kobi Perl, Igor Ulitsky, Karen B. Avraham

Sci Rep. 2017; 7: 8637. Published online 2017 Aug 17. doi: 10.1038/s41598-017-08320-3

PMCID:: PMC5561060

Article PDF–4.9M

Select item 308230720.

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass

Lucy H. Williams, Sundeep Kalantry, Joshua Starmer, Terry Magnuson

Development. 2011 May 15; 138(10): 2049–2057. doi: 10.1242/dev.061176

PMCID:: PMC3082307

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