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Items: 1 to 20 of 52

1.
Cell‐density‐dependent Expression of Cyp1a2 Gene in Monolayer‐cultured Adult Mouse Hepatocytes
Nobuo Nemoto, Junko Sakurai
Jpn J Cancer Res. 1993 Mar; 84(3): 265–271. doi: 10.1111/j.1349-7006.1993.tb02866.x
PMCID:
PMC5919153
ArticlePDF–629K
2.
Activation of Cyp1a1 and Cyp1a2 Genes in Adult Mouse Hepatocytes in Primary Culture
Nobuo Nemoto, Junko Sakurai
Jpn J Cancer Res. 1993 Mar; 84(3): 272–278. doi: 10.1111/j.1349-7006.1993.tb02867.x
PMCID:
PMC5919143
ArticlePDF–509K
3.
Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the Mouse
Thomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith, Arthur P. Grollman
Drug Metab Dispos. 2010 May; 38(5): 761–768. doi: 10.1124/dmd.110.032201
PMCID:
PMC2872943
ArticlePDF–597K
4.
Mouse cytochrome P3-450: complete cDNA and amino acid sequence.
S Kimura, F J Gonzalez, D W Nebert
Nucleic Acids Res. 1984 Mar 26; 12(6): 2917–2928. doi: 10.1093/nar/12.6.2917
Correction in:
Nucleic Acids Res. 1984 Jun 11; 12(11): 4810.
PMCID:
PMC318715
SummaryPage BrowsePDF–884K
5.
cDNA and complete amino acid sequence of mouse P2(450): allelic variant of mouse P3(450) gene.
S Kimura, D W Nebert
Nucleic Acids Res. 1986 Aug 26; 14(16): 6765–6766. doi: 10.1093/nar/14.16.6765
PMCID:
PMC311679
SummaryPage BrowsePDF–140K
6.
Molecular Mechanisms of Pulmonary Carcinogenesis by Polycyclic Aromatic Hydrocarbons (PAHs): Implications for Human Lung Cancer
Rachel Stading, Grady Gastelum, Chun Chu, Weiwu Jiang, Bhagavatula Moorthy
Semin Cancer Biol. Author manuscript; available in PMC 2022 Jan 5.
Published in final edited form as: Semin Cancer Biol. 2021 Nov; 76: 3–16. Published online 2021 Jul 7. doi: 10.1016/j.semcancer.2021.07.001
PMCID:
PMC8728691
ArticlePDF–1.9M
7.
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2
Grady Gastelum, Weiwu Jiang, Lihua Wang, Guodong Zhou, Roshan Borkar, Nagireddy Putluri, Bhagavatula Moorthy
Toxicol Sci. 2020 Oct; 177(2): 347–361. Published online 2020 Jul 29. doi: 10.1093/toxsci/kfaa107
PMCID:
PMC7818899
ArticlePDF–1.4M
8.
Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode, C. R. Wolf
Drug Metab Dispos. 2019 Aug; 47(8): 907–918. Published online 2019 Jul 19. doi: 10.1124/dmd.119.087718
PMCID:
PMC6657216
ArticlePDF–1.4M
9.
Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders
Kelsey Klinefelter, Molly Kromme Hooven, Chloe Bates, Breann T. Colter, Alexandra Dailey, Smitha Krishnan Infante, Izabela Kania-Korwel, Hans-Joachim Lehmler, Alejandro López-Juárez, Clare Pickering Ludwig, Christine Perdan Curran
Mamm Genome. Author manuscript; available in PMC 2019 Mar 20.
Published in final edited form as: Mamm Genome. 2018 Feb; 29(1-2): 112–127. Published online 2017 Dec 2. doi: 10.1007/s00335-017-9728-1
PMCID:
PMC6425730
ArticlePDF–1.5M
10.
Species Difference among Experimental Rodents in Induction of P450IA Family Enzymes by 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine
Masakuni Degawa, Ken‐ichiro Kobayashi, Shin‐ichi Miura, Hiroshi Arai, Hiroyasu Esumi, Takashi Sugimura, Yoshiyuki Hashimoto
Jpn J Cancer Res. 1992 Oct; 83(10): 1047–1051. doi: 10.1111/j.1349-7006.1992.tb02720.x
PMCID:
PMC5918673
ArticlePDF–504K
11.
2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
Shangfu Xu, Jie Liu, Jingshan Shi, Zhengtao Wang, Lili Ji
Sci Rep. 2017; 7: 16511. Published online 2017 Nov 28. doi: 10.1038/s41598-017-16688-5
PMCID:
PMC5705655
ArticlePDF–8.6M
12.
Disruption of Cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury
Lihua Wang, Krithika Lingappan, Weiwu Jiang, Xanthi I. Couroucli, Stephen E. Welty, Binoy Shivanna, Roberto Barrios, Gangduo Wang, M. Firoze Khan, Frank J. Gonzalez, L Jackson Roberts, Bhagavatula Moorthy
Free Radic Biol Med. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Free Radic Biol Med. 2015 May; 82: 147–159. Published online 2015 Feb 10. doi: 10.1016/j.freeradbiomed.2015.01.019
PMCID:
PMC4418801
ArticlePDF–1.9M
13.
Sex-specific differences in hyperoxic lung injury in mice: role of Cytochrome P450 (CYP)1A
Krithika Lingappan, Weiwu Jiang, Lihua Wang, Xanthi I. Couroucli, Bhagavatula Moorthy
Toxicology. Author manuscript; available in PMC 2016 May 4.
Published in final edited form as: Toxicology. 2015 May 4; 331: 14–23. Published online 2015 Feb 19. doi: 10.1016/j.tox.2015.01.019
PMCID:
PMC4406849
ArticlePDF–3.7M
14.
N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
Shuang Wang, Kim S. Sugamori, Aveline Tung, J. Peter McPherson, Denis M. Grant
Toxicol Sci. 2015 Apr; 144(2): 393–405. Published online 2015 Jan 19. doi: 10.1093/toxsci/kfv006
PMCID:
PMC4372667
ArticlePDF–636K
15.
AhrdCyp1a2(−/−) mice show increased susceptibility to PCB-induced developmental neurotoxicity
Christine Perdan Curran, Emily Altenhofen, Amy Ashworth, Austin Brown, Cellestine Kamau-Cheggeh, Melinda Curran, Amber Evans, Rikki Floyd, Jocelyn Fowler, Helen Garber, Breann Hays, Sarah Kraemer, Anna Lang, Andrea Mynhier, Ashton Samuels, Carly Strohmaier
Neurotoxicology. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Neurotoxicology. 2012 Dec; 33(6): 1436–1442. Published online 2012 Aug 23. doi: 10.1016/j.neuro.2012.08.005
PMCID:
PMC3518762
ArticlePDF–2.7M
16.
In Utero and Lactational Exposure to PCBs in Mice: Adult Offspring Show Altered Learning and Memory Depending on Cyp1a2 and Ahr Genotypes
Christine P. Curran, Daniel W. Nebert, Mary Beth Genter, Krishna V. Patel, Tori L. Schaefer, Matthew R. Skelton, Michael T. Williams, Charles V. Vorhees
Environ Health Perspect. 2011 Sep; 119(9): 1286–1293. Published online 2011 May 13. doi: 10.1289/ehp.1002965
PMCID:
PMC3230394
ArticlePDF–722K
17.
UROPORPHYRIA IN THE Cyp1a2−/− MOUSE
John D. Phillips, James P. Kushner, Hector A. Bergonia, Michael R. Franklin
Blood Cells Mol Dis. Author manuscript; available in PMC 2012 Dec 15.
Published in final edited form as: Blood Cells Mol Dis. 2011 Dec 15; 47(4): 249–254. Published online 2011 Aug 30. doi: 10.1016/j.bcmd.2011.07.006
PMCID:
PMC3223295
ArticlePDF–789K
18.
Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate
Connie Cheung, Shea Loy, Guang Xun Li, Anna B. Liu, Chung S. Yang
Carcinogenesis. 2011 Feb; 32(2): 233–239. Published online 2010 Nov 15. doi: 10.1093/carcin/bgq235
PMCID:
PMC3026842
ArticlePDF–452K
19.
In Utero and Lactational Exposure to a Complex Mixture of Polychlorinated Biphenyls: Toxicity in Pups Dependent on the Cyp1a2 and Ahr Genotypes
Christine P. Curran, Charles V. Vorhees, Michael T. Williams, Mary Beth Genter, Marian L. Miller, Daniel W. Nebert
Toxicol Sci. 2011 Jan; 119(1): 189–208. Published online 2010 Oct 20. doi: 10.1093/toxsci/kfq314
PMCID:
PMC3003831
ArticlePDF–606K
20.
Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significanly correlated with cytochrome P450 suppression
Xia Chen, Chang-Kai Sun, Guo-Zhu Han, Jin-Yong Peng, Ying Li, Yan-Xia Liu, Yuan-Yuan Lv, Ke-Xin Liu, Qin Zhou, Hui-Jun Sun
World J Gastroenterol. 2009 Apr 21; 15(15): 1829–1835. Published online 2009 Apr 21. doi: 10.3748/wjg.15.1829
PMCID:
PMC2670409
ArticlePDF–991K

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