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Items: 1 to 20 of 79

1.
Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse
Christian Secchi, Martina Belli, Tracy N. H. Harrison, Joseph Swift, CheMyong Ko, Antoni J. Duleba, Dwayne Stupack, R. Jeffrey Chang, Shunichi Shimasaki
J Transl Med. 2021; 19: 428. Published online 2021 Oct 15. doi: 10.1186/s12967-021-03103-x
PMCID:
PMC8520195
AbstractArticlePDF–2.3M
2.
Effect of Differences in the Microbiome of Cyp17a1-Deficient Mice on Atherosclerotic Background
Axel Künstner, Redouane Aherrahrou, Misa Hirose, Petra Bruse, Saleh Mohamed Ibrahim, Hauke Busch, Jeanette Erdmann, Zouhair Aherrahrou
Cells. 2021 Jun; 10(6): 1292. Published online 2021 May 23. doi: 10.3390/cells10061292
PMCID:
PMC8224745
AbstractArticlePDF–522K
3.
CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development
Redouane Aherrahrou, Alexandra E. Kulle, Natalia Alenina, Ralf Werner, Simeon Vens-Cappell, Michael Bader, Heribert Schunkert, Jeanette Erdmann, Zouhair Aherrahrou
Sci Rep. 2020; 10: 8792. Published online 2020 May 29. doi: 10.1038/s41598-020-65601-0
PMCID:
PMC7260244
AbstractArticlePDF–2.2M
4.
Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease
Ting-Ting Wu, Ying-Ying Zheng, Xiang Ma, Wen-Juan Xiu, Hai-Tao Yang, Xian-Geng Hou, Yi Yang, You Chen, Yi-Tong Ma, Xiang Xie
Cell Commun Signal. 2023; 21: 155. Published online 2023 Jun 27. doi: 10.1186/s12964-023-01061-z
PMCID:
PMC10294473
AbstractArticlePDF–6.0M
5.
Hydroxylation and Lyase Reactions of Steroids Catalyzed by Mouse Cytochrome P450 17A1 (Cyp17a1)
Sung-Gyu Lee, Vitchan Kim, Gyu-Hyeong Lee, Changmin Kim, Eunseo Jeong, F. Peter Guengerich, Donghak Kim
J Inorg Biochem. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: J Inorg Biochem. 2023 Mar; 240: 112085. Published online 2023 Jan 10. doi: 10.1016/j.jinorgbio.2022.112085
PMCID:
PMC9892303
AbstractArticlePDF–857K
6.
Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells
Varun Sondhi, Bryn M. Owen, Jiayan Liu, Robert Chomic, Steven A. Kliewer, Beverly A. Hughes, Wiebke Arlt, David J. Mangelsdorf, Richard J. Auchus
Mol Endocrinol. 2016 Apr; 30(4): 469–478. Published online 2016 Mar 14. doi: 10.1210/me.2015-1282
PMCID:
PMC4814474
AbstractArticle
7.
The Src tyrosine kinase pathway regulates thecal CYP17 expression and androstenedione secretion
Gaurav Chaturvedi, Koji Arai, Paul F. Terranova, Katherine F. Roby
Mol Cell Biochem. Author manuscript; available in PMC 2015 Feb 12.
Published in final edited form as: Mol Cell Biochem. 2008 Nov; 318(0): 191–200. Published online 2008 Jul 19. doi: 10.1007/s11010-008-9871-9
PMCID:
PMC4326000
AbstractArticlePDF–333K
8.
Deletion of the Mouse P450c17 Gene Causes Early Embryonic Lethality
Susanna R. Bair, Synthia H. Mellon
Mol Cell Biol. 2004 Jun; 24(12): 5383–5390. doi: 10.1128/MCB.24.12.5383-5390.2004
PMCID:
PMC419874
AbstractArticlePDF–564K
9.
Differential Regulation Of Steroidogenic Enzyme Genes by TRα Signaling in Testicular Leydig Cells
Eunsook Park, Yeawon Kim, Hyun Joo Lee, Keesook Lee
Mol Endocrinol. 2014 Jun; 28(6): 822–833. Published online 2014 Apr 11. doi: 10.1210/me.2013-1150
PMCID:
PMC5414843
AbstractArticle
10.
Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis
Sayeepriyadarshini Anakk, Mitsuhiro Watanabe, Scott A. Ochsner, Neil J. McKenna, Milton J. Finegold, David D. Moore
J Clin Invest. 2011 Jan 4; 121(1): 86–95. Published online 2010 Dec 1. doi: 10.1172/JCI42846
PMCID:
PMC3007143
AbstractArticlePDF–1.0M
11.
Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance
Sung-Mi Kim, Ji-Young Kim, Nak-Won Choe, Ick-Hyun Cho, Ju-Ryoung Kim, Dong-Wook Kim, Jin-Ee Seol, Song Eun Lee, Hoon Kook, Kwang-Il Nam, Hyun Kook, Young-Yil Bhak, Sang-Beom Seo
Nucleic Acids Res. 2010 Oct; 38(19): 6389–6403. Published online 2010 Jun 8. doi: 10.1093/nar/gkq491
PMCID:
PMC2965226
AbstractArticlePDF–2.3M
12.
A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: phenotype and impact on adrenocortical function
Isaac Levy, Eva Szarek, Andrea Gutierrez Maria, Matthew Starrost, Maria De La Luz Sierra, Fabio R. Faucz, Constantine A. Stratakis
Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jan 15.
Published in final edited form as: Mol Cell Endocrinol. 2021 Jan 15; 520: 111071. Published online 2020 Oct 27. doi: 10.1016/j.mce.2020.111071
PMCID:
PMC7771190
AbstractArticlePDF–2.5M
13.
MEF2 Is Restricted to the Male Gonad and Regulates Expression of the Orphan Nuclear Receptor NR4A1
Caroline Daems, Luc J. Martin, Catherine Brousseau, Jacques J. Tremblay
Mol Endocrinol. 2014 Jun; 28(6): 886–898. Published online 2014 Apr 2. doi: 10.1210/me.2013-1407
PMCID:
PMC5414842
AbstractArticle
14.
Mamld1 Knockdown Reduces Testosterone Production and Cyp17a1 Expression in Mouse Leydig Tumor Cells
Michiko Nakamura, Maki Fukami, Fumihiro Sugawa, Mami Miyado, Katsuya Nonomura, Tsutomu Ogata
PLoS One. 2011; 6(4): e19123. Published online 2011 Apr 29. doi: 10.1371/journal.pone.0019123
PMCID:
PMC3084764
AbstractArticlePDF–313K
15.
Regulation of P450c17 Expression in the Early Embryo Depends on GATA Factors
Yimin Shi, Marcus D. Schonemann, Synthia H. Mellon
Endocrinology. 2009 Feb; 150(2): 946–956. Published online 2008 Oct 1. doi: 10.1210/en.2008-0573
PMCID:
PMC2646537
AbstractArticle
16.
Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids.
Y Sadovsky, P A Crawford, K G Woodson, J A Polish, M A Clements, L M Tourtellotte, K Simburger, J Milbrandt
Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24): 10939–10943. doi: 10.1073/pnas.92.24.10939
PMCID:
PMC40546
SummaryPage BrowsePDF–1.8M
17.
FOXL2 interaction with different binding partners regulates the dynamics of ovarian development
Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge
Sci Adv. 2024 Mar 22; 10(12): eadl0788. Published online 2024 Mar 22. doi: 10.1126/sciadv.adl0788
PMCID:
PMC10959415
AbstractArticlePDF–4.4M
18.
Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain
Philipp Wartenberg, Imre Farkas, Veronika Csillag, William H. Colledge, Erik Hrabovszky, Ulrich Boehm
J Neurosci. 2021 Nov 3; 41(44): 9177–9191. doi: 10.1523/JNEUROSCI.0885-21.2021
PMCID:
PMC8570831
AbstractArticlePDF–9.6M
19.
Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice
J. Philippe York, Yi Athena Ren, Jie Zeng, Bin Zhang, Fang Wang, Rui Chen, Jianqiao Liu, Xuefeng Xia, Pumin Zhang
Sci Rep. 2016; 6: 34956. Published online 2016 Oct 13. doi: 10.1038/srep34956
PMCID:
PMC5062118
AbstractArticlePDF–3.5M
20.
Redundant and Differential Roles of Transcription Factors Gli1 and Gli2 in the Development of Mouse Fetal Leydig Cells
Ivraym Barsoum, Humphrey H.C. Yao
Biol Reprod. 2011 May; 84(5): 894–899. Published online 2011 Jan 5. doi: 10.1095/biolreprod.110.088997
PMCID:
PMC4574634
AbstractArticlePDF–2.7M

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