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Select item 106203991.

Henry Oppermann, Elia Marcos-Grañeda, Linnea A. Weiss, Christina A. Gurnett, Anne Marie Jelsig, Susanne H. Vineke, Bertrand Isidor, Sandra Mercier, Kari Magnussen, Pia Zacher, Mona Hashim, Alistair T. Pagnamenta, Simone Race, Siddharth Srivastava, Zoë Frazier, Robert Maiwald, Matthias Pergande, Donatella Milani, Martina Rinelli, Jonathan Levy, Ilona Krey, Paolo Fontana, Fortunato Lonardo, Stephanie Riley, Jasmine Kretzer, Julia Rankin, Linda M. Reis, Elena V. Semina, Miriam S. Reuter, Stephen W. Scherer, Maria Iascone, Denisa Weis, Christina R. Fagerberg, Charlotte Brasch-Andersen, Lars Kjaersgaard Hansen, Alma Kuechler, Nathan Noble, Alice Gardham, Jessica Tenney, Geetanjali Rathore, Stefanie Beck-Woedl, Tobias B. Haack, Despoina C. Pavlidou, Isis Atallah, Julia Vodopiutz, Andreas R. Janecke, Tzung-Chien Hsieh, Hellen Lesmann, Hannah Klinkhammer, Peter M. Krawitz, Johannes R. Lemke, Rami Abou Jamra, Marta Nieto, Zeynep Tümer, Konrad Platzer

Eur J Hum Genet. 2023 Nov; 31(11): 1251–1260. Published online 2023 Aug 30. doi: 10.1038/s41431-023-01445-2

PMCID:: PMC10620399

Abstract Article PDF–3.6M

Select item 84142612.

Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

Molly K. Imgruet, Julian Lutze, Ningfei An, Bonnie Hu, Saira Khan, Jeffrey Kurkewich, Tanner C. Martinez, Donald Wolfgeher, Sandeep K. Gurbuxani, Stephen J. Kron, Megan E. McNerney

Blood. 2021 Sep 2; 138(9): 790–805. Prepublished online 2021 May 27. doi: 10.1182/blood.2020009195

PMCID:: PMC8414261

Abstract Article

Select item 44414153.

Hepatomegaly in Transgenic Mice Expressing the Homeobox Gene Cux-1

Gregory B. Vanden Heuvel, Jennifer G. Brantley, Neal I. Alcalay, Madhulika Sharma, Gabor Kemeny, Joshua Warolin, Aric W. Ledford, David M. Pinson

Mol Carcinog. Author manuscript; available in PMC 2015 May 22.

Published in final edited form as: Mol Carcinog. 2005 May; 43(1): 18–30. doi: 10.1002/mc.20091

PMCID:: PMC4441415

Abstract Article PDF–4.1M

Select item 44141414.

The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

Zubaidah M. Ramdzan, Ranjana Pal, Simran Kaur, Lam Leduy, Ginette Bérubé, Sayeh Davoudi, Charles Vadnais, Alain Nepveu

Oncotarget. 2015 Feb; 6(6): 3613–3626. Published online 2015 Feb 17. doi: 10.18632/oncotarget.2919

PMCID:: PMC4414141

Abstract Article PDF–3.4M

Select item 33788815.

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

Charles Vadnais, Sayeh Davoudi, Mojdeh Afshin, Ryoko Harada, Rachel Dudley, Pier-Luc Clermont, Elliot Drobetsky, Alain Nepveu

Nucleic Acids Res. 2012 May; 40(10): 4483–4495. Published online 2012 Feb 8. doi: 10.1093/nar/gks041

PMCID:: PMC3378881

Abstract Article PDF–6.7M

Select item 30431286.

Asynchronous Expression of the Homeodomain Protein CUX1 in Sertoli Cells and Spermatids During Spermatogenesis in Mice

Melissa R. Kroll, Engela S. Viss, Jonathan Lamb, Joy Horstman, Alexander Powell, Andrea Van Wyk, Kaarlo Hinkkala, Traci Hoogland, Matthew Schippers, Stephen Shannon, Carol G. Carlton, Madhulika Sharma, Aaron Taylor, Gregory B. Vanden Heuvel, Tony N. Jelsma

Biol Reprod. 2011 Mar; 84(3): 455–465. Published online 2010 Oct 27. doi: 10.1095/biolreprod.110.084335

PMCID:: PMC3043128

Abstract Article PDF–11M

Select item 16368677.

Differentiation-Induced Cleavage of Cutl1/CDP Generates a Novel Dominant-Negative Isoform That Regulates Mammary Gene Expression

Urmila Maitra, Jin Seo, Mary M. Lozano, Jaquelin P. Dudley

Mol Cell Biol. 2006 Oct; 26(20): 7466–7478. doi: 10.1128/MCB.01083-06

PMCID:: PMC1636867

Abstract Article PDF–547K

Select item 14302908.

The p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase

Laurent Sansregret, Brigitte Goulet, Ryoko Harada, Brian Wilson, Lam Leduy, Jacques Bertoglio, Alain Nepveu

Mol Cell Biol. 2006 Mar; 26(6): 2441–2455. doi: 10.1128/MCB.26.6.2441-2455.2006

PMCID:: PMC1430290

Abstract Article PDF–841K

Select item 5078559.

Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic kidney cultures.

S E Quaggin, H Yeger, P Igarashi

J Clin Invest. 1997 Feb 15; 99(4): 718–724. doi: 10.1172/JCI119216

PMCID:: PMC507855

Summary PDF–517K

Select item 41640110.

The Homeodomain Protein CDP Regulates Mammary-Specific Gene Transcription and Tumorigenesis

Quan Zhu, Urmila Maitra, Dennis Johnston, Mary Lozano, Jaquelin P. Dudley

Mol Cell Biol. 2004 Jun; 24(11): 4810–4823. doi: 10.1128/MCB.24.11.4810-4823.2004

PMCID:: PMC416401

Abstract Article PDF–584K

Select item 23153311.

The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.

F Mailly, G Bérubé, R Harada, P L Mao, S Phillips, A Nepveu

Mol Cell Biol. 1996 Oct; 16(10): 5346–5357. doi: 10.1128/mcb.16.10.5346

PMCID:: PMC231533

Summary PDF–736K

Select item 13393012.

A Novel Colonic Repressor Element Regulates Intestinal Gene Expression by Interacting with Cux/CDP

François Boudreau, Edmond H. H. M. Rings, Gary P. Swain, Angus M. Sinclair, Eun Ran Suh, Debra G. Silberg, Richard H. Scheuermann, Peter G. Traber

Mol Cell Biol. 2002 Aug; 22(15): 5467–5478. doi: 10.1128/MCB.22.15.5467-5478.2002

PMCID:: PMC133930

Abstract Article PDF–956K

Select item 8388613.

Cux/CDP Homeoprotein Is a Component of NF-μNR and Represses the Immunoglobulin Heavy Chain Intronic Enhancer by Antagonizing the Bright Transcription Activator

Zhiyong Wang, Adrian Goldstein, Rui-Ting Zong, Danjun Lin, Ellis J. Neufeld, Richard H. Scheuermann, Philip W. Tucker

Mol Cell Biol. 1999 Jan; 19(1): 284–295. doi: 10.1128/mcb.19.1.284

PMCID:: PMC83886

Abstract Article PDF–978K

Select item 911413314.

CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate

Toshimitsu Suzuki, Tetsuya Tatsukawa, Genki Sudo, Caroline Delandre, Yun Jin Pai, Hiroyuki Miyamoto, Matthieu Raveau, Atsushi Shimohata, Iori Ohmori, Shin-ichiro Hamano, Kazuhiro Haginoya, Mitsugu Uematsu, Yukitoshi Takahashi, Masafumi Morimoto, Shinji Fujimoto, Hitoshi Osaka, Hirokazu Oguni, Makiko Osawa, Atsushi Ishii, Shinichi Hirose, Sunao Kaneko, Yushi Inoue, Adrian Walton Moore, Kazuhiro Yamakawa

Sci Rep. 2022; 12: 6505. Published online 2022 May 17. doi: 10.1038/s41598-022-10715-w

PMCID:: PMC9114133

Abstract Article PDF–7.6M

Select item 394967315.

RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage

Zubaidah M. Ramdzan, Charles Vadnais, Ranjana Pal, Guillaume Vandal, Chantal Cadieux, Lam Leduy, Sayeh Davoudi, Laura Hulea, Lu Yao, Anthony N. Karnezis, Marilène Paquet, David Dankort, Alain Nepveu

PLoS Biol. 2014 Mar; 12(3): e1001807. Published online 2014 Mar 11. doi: 10.1371/journal.pbio.1001807

PMCID:: PMC3949673

Abstract Article PDF–3.2M

Select item 310340016.

High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1

Maria Fragiadaki, Tetsurou Ikeda, Abigail Witherden, Roger M Mason, David Abraham, George Bou-Gharios

Mol Biol Cell. 2011 Jun 1; 22(11): 1836–1844. doi: 10.1091/mbc.E10-08-0669

PMCID:: PMC3103400

Abstract Article PDF–985K

Select item 293896017.

Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons

Beatriz Cubelos, Alvaro Sebastián-Serrano, Seonhee Kim, Juan Miguel Redondo, Christopher Walsh, Marta Nieto

Dev Neurobiol. Author manuscript; available in PMC 2010 Sep 14.

Published in final edited form as: Dev Neurobiol. 2008 Jun; 68(7): 917–925. doi: 10.1002/dneu.20626

PMCID:: PMC2938960

Abstract Article PDF–4.3M

Select item 273106918.

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice

Rania Siam, Ryoko Harada, Chantal Cadieux, Robert Battat, Charles Vadnais, Alain Nepveu

Mol Cancer. 2009; 8: 60. Published online 2009 Aug 5. doi: 10.1186/1476-4598-8-60

PMCID:: PMC2731069

Abstract Article PDF–1.0M

Select item 31277619.

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

Tammy Ellis, Laure Gambardella, Markus Horcher, Stefan Tschanz, Janine Capol, Paula Bertram, Wolfram Jochum, Yann Barrandon, Meinrad Busslinger

Genes Dev. 2001 Sep 1; 15(17): 2307–2319. doi: 10.1101/gad.200101

PMCID:: PMC312776

Abstract Article PDF–1.5M

Select item 13468620.

Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility

Mai X. Luong, Caroline M. van der Meijden, DongXia Xing, Ruth Hesselton, Edwin S. Monuki, Stephen N. Jones, Jane B. Lian, Janet L. Stein, Gary S. Stein, Ellis J. Neufeld, Andre J. van Wijnen

Mol Cell Biol. 2002 Mar; 22(5): 1424–1437. doi: 10.1128/mcb.22.5.1424-1437.2002

PMCID:: PMC134686

Abstract Article PDF–1.2M

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