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Select item 106858501.

CRAT links cholesterol metabolism to innate immune responses in the heart

Hua Mao, Aude Angelini, Shengyu Li, Guangyu Wang, Luge Li, Cam Patterson, Xinchun Pi, Liang Xie

Nat Metab. Author manuscript; available in PMC 2023 Nov 29.

Published in final edited form as: Nat Metab. 2023 Aug; 5(8): 1382–1394. Published online 2023 Jul 13. doi: 10.1038/s42255-023-00844-5

PMCID:: PMC10685850

Article PDF–4.4M

Select item 87414972.

Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome

Ashley S. Williams, Timothy R. Koves, Yasminye D. Pettway, James A. Draper, Dorothy H. Slentz, Paul A. Grimsrud, Olga R. Ilkayeva, Deborah M. Muoio

iScience. 2022 Jan 21; 25(1): 103635. Published online 2021 Dec 16. doi: 10.1016/j.isci.2021.103635

PMCID:: PMC8741497

Article PDF–4.4M

Select item 47540833.

The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-induced Lysine Acetylation of Mitochondrial Proteins

Michael N. Davies, Lilja Kjalarsdottir, J. Will Thompson, Laura G. Dubois, Robert D. Stevens, Olga R. Ilkayeva, M. Julia Brosnan, Timothy P. Rolph, Paul A. Grimsrud, Deborah M. Muoio

Cell Rep. Author manuscript; available in PMC 2016 Feb 15.

Published in final edited form as: Cell Rep. 2016 Jan 12; 14(2): 243–254. Published online 2015 Dec 31. doi: 10.1016/j.celrep.2015.12.030

PMCID:: PMC4754083

Article PDF–2.1M

Select item 29408344.

Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates

Yu-Shan Hsiao, Gerwald Jogl, Liang Tong

J Biol Chem. Author manuscript; available in PMC 2010 Sep 16.

Published in final edited form as: J Biol Chem. 2006 Sep 22; 281(38): 28480–28487. Published online 2006 Jul 26. doi: 10.1074/jbc.M602622200

PMCID:: PMC2940834

Article PDF–957K

Select item 12182055.

Cloning and characterization of murine carnitine acetyltransferase: evidence for a requirement during cell cycle progression.

S Brunner, K Kramar, D T Denhardt, R Hofbauer

Biochem J. 1997 Mar 1; 322(Pt 2): 403–410. doi: 10.1042/bj3220403

PMCID:: PMC1218205

Summary PDF–670K

Select item 106523216.

Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction‐induced cellular senescence in dermal fibroblasts

Min Ji Song, Chi‐Hyun Park, Haesoo Kim, Sangbum Han, Si Hyung Lee, Dong Hun Lee, Jin Ho Chung

Aging Cell. 2023 Nov; 22(11): e14000. Published online 2023 Oct 13. doi: 10.1111/acel.14000

PMCID:: PMC10652321

Article PDF–24M

Select item 72257407.

A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion

Dassine Berdous, Xavier Berney, Ana Rodriguez Sanchez-Archidona, Maxime Jan, Clara Roujeau, Isabel C. Lopez-Mejia, Randall Mynatt, Bernard Thorens

Mol Metab. 2020 Jul; 37: 100993. Published online 2020 Apr 13. doi: 10.1016/j.molmet.2020.100993

PMCID:: PMC7225740

Article PDF–2.0M

Select item 69522418.

Disruption of acetyl-lysine turnover in muscle mitochondria promotes insulin resistance and redox stress without overt respiratory dysfunction

Ashley S. Williams, Timothy R. Koves, Michael T. Davidson, Scott B. Crown, Kelsey H. Fisher-Wellman, Maria J. Torres, James A. Draper, Tara M. Narowski, Dorothy H. Slentz, Louise Lantier, David H. Wasserman, Paul A. Grimsrud, Deborah M. Muoio

Cell Metab. Author manuscript; available in PMC 2021 Jan 7.

Published in final edited form as: Cell Metab. 2020 Jan 7; 31(1): 131–147.e11. Published online 2019 Dec 5. doi: 10.1016/j.cmet.2019.11.003

PMCID:: PMC6952241

Article PDF–2.1M

Select item 66928869.

Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice

Alex Reichenbach, Mathieu Mequinion, Jacqueline A Bayliss, Sarah H Lockie, Moyra B Lemus, Randall L Mynatt, Romana Stark, Zane B Andrews

Endocrinology. 2018 Jun; 159(6): 2473–2483. Published online 2018 Apr 24. doi: 10.1210/en.2018-00131

PMCID:: PMC6692886

Article

Select item 642587310.

Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis

Claudia Kruger, Trang-Tiffany Nguyen, Chelsea Breaux, Alana Guillory, Margaret Mangelli, Kevin T. Fridianto, Jean-Paul Kovalik, David H. Burk, Robert C. Noland, Randall Mynatt, Krisztian Stadler

Diabetes. 2019 Apr; 68(4): 819–831. Published online 2019 Feb 6. doi: 10.2337/db18-0090

PMCID:: PMC6425873

Article PDF–2.3M

Select item 527993411.

Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation

Emily L. Goldberg, Vishwa Deep Dixit

Mol Metab. 2017 Feb; 6(2): 219–225. Published online 2017 Jan 3. doi: 10.1016/j.molmet.2016.12.008

PMCID:: PMC5279934

Article PDF–1.5M

Select item 475408212.

Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue During Exercise

Sarah E. Seiler, Timothy R. Koves, Jessica R. Gooding, Kari E. Wong, Robert S. Stevens, Olga R. Ilkayeva, April H. Wittmann, Karen L. DeBalsi, Michael N. Davies, Lucas Lindeboom, Patrick Schrauwen, Vera B. Schrauwen-Hinderling, Deborah M. Muoio

Cell Metab. Author manuscript; available in PMC 2016 Jul 7.

Published in final edited form as: Cell Metab. 2015 Jul 7; 22(1): 65–76. doi: 10.1016/j.cmet.2015.06.003

PMCID:: PMC4754082

Article PDF–1.3M

Select item 334851513.

Muscle-specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility

Deborah M. Muoio, Robert C. Noland, Jean-Paul Kovalik, Sarah E. Seiler, Michael N. Davies, Karen L. DeBalsi, Olga R. Ilkayeva, Robert D. Stevens, Indu Kheterpal, Jingying Zhang, Jeffrey D. Covington, Sudip Bajpeyi, Eric Ravussin, William Kraus, Timothy R. Koves, Randall L. Mynatt

Cell Metab. Author manuscript; available in PMC 2013 May 2.

Published in final edited form as: Cell Metab. 2012 May 2; 15(5): 764–777. doi: 10.1016/j.cmet.2012.04.005

PMCID:: PMC3348515

Article PDF–5.9M

Select item 122410314.

Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.

Montserrat Morillas, Eduardo López-VViñas, Alfonso Valencia, Dolors Serra, Paulino Gómez-Puertas, Fausto G Hegardt, Guillermina Asins

Biochem J. 2004 May 1; 379(Pt 3): 777–784. doi: 10.1042/BJ20031373

PMCID:: PMC1224103

Summary PDF–385K

Select item 627576515.

The carnitine acetyltransferase gene (CRAT): A characterization of porcine transcripts with insights into the 5’-end variants of mammalian transcripts and their possible sub-cellular localization

Annie Robic, Thomas Faraut, Laurence Liaubet, Denis Milan

Cell Mol Biol Lett. 2009 Mar; 14(1): 90–99. Published online 2008 Oct 6. doi: 10.2478/s11658-008-0036-3

PMCID:: PMC6275765

Summary PDF–571K

Select item 460561016.

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome

Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin

PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994

PMCID:: PMC4605610

Article PDF–6.8M

Select item 277884417.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Article PDF–1.2M

Select item 30876318.

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller, Gregor Eichele

Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029

PMCID:: PMC308763

Article PDF–253K

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

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