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Select item 100398981.

Phosphate induces inflammation and exacerbates injury from cigarette smoke in the bronchial epithelium

Seth Bollenbecker, Kylie Heitman, Brian Czaya, Molly Easter, Meghan June Hirsch, Shia Vang, Elex Harris, E. Scott Helton, Jarrod W. Barnes, Christian Faul, Stefanie Krick

Sci Rep. 2023; 13: 4898. Published online 2023 Mar 25. doi: 10.1038/s41598-023-32053-1

PMCID:: PMC10039898

Abstract Article PDF–21M

Select item 90351712.

Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease

Mark R. Hanudel, Brian Czaya, Shirley Wong, Grace Jung, Kristine Chua, Bo Qiao, Victoria Gabayan, Tomas Ganz

Sci Rep. 2022; 12: 6695. Published online 2022 Apr 23. doi: 10.1038/s41598-022-10842-4

PMCID:: PMC9035171

Abstract Article PDF–3.3M

Select item 89121763.

TNF-α induces Claudin-1 expression in renal tubules in Alport mice

Manami Iida, Shuichi Ohtomo, Naoko A. Wada, Otoya Ueda, Yoshinori Tsuboi, Atsuo Kurata, Kou-ichi Jishage, Naoshi Horiba

PLoS One. 2022; 17(3): e0265081. Published online 2022 Mar 10. doi: 10.1371/journal.pone.0265081

PMCID:: PMC8912176

Abstract Article PDF–1.7M

Select item 88699264.

Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models

Diana Rubel, Joseph Boulanger, Florin Craciun, Ethan Y. Xu, Yanqin Zhang, Lucy Phillips, Michelle Callahan, William Weber, Wenping Song, Nicholas Ngai, Nikolay O. Bukanov, Xingyi Shi, Ali Hariri, Hervé Husson, Oxana Ibraghimov-Beskrovnaya, Shiguang Liu, Oliver Gross

Cells. 2022 Feb; 11(4): 594. Published online 2022 Feb 9. doi: 10.3390/cells11040594

PMCID:: PMC8869926

Abstract Article PDF–22M

Select item 83291975.

Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease

Matthew B. Wright, Javier Varona Santos, Christian Kemmer, Cyrille Maugeais, Jean-Philippe Carralot, Stephan Roever, Judith Molina, G. Michelle Ducasa, Alla Mitrofanova, Alexis Sloan, Anis Ahmad, Christopher Pedigo, Mengyuan Ge, Jeffrey Pressly, Laura Barisoni, Armando Mendez, Jacopo Sgrignani, Andrea Cavalli, Sandra Merscher, Marco Prunotto, Alessia Fornoni

Nat Commun. 2021; 12: 4662. Published online 2021 Aug 2. doi: 10.1038/s41467-021-24890-3

PMCID:: PMC8329197

Abstract Article PDF–2.7M

Select item 81000706.

Collagen IV^α345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases

Elena N. Pokidysheva, Harald Seeger, Vadim Pedchenko, Sergei Chetyrkin, Carsten Bergmann, Dale Abrahamson, Zhao Wei Cui, Eric Delpire, Fernando C. Fervenza, Aaron L. Fidler, Agnes B. Fogo, Ariana Gaspert, Maik Grohmann, Oliver Gross, George Haddad, Raymond C. Harris, Clifford Kashtan, A. Richard Kitching, Johan M. Lorenzen, Stephen McAdoo, Charles D. Pusey, Marten Segelmark, Alicia Simmons, Paul A. Voziyan, Timo Wagner, Rudolf P. Wüthrich, Ming-Hui Zhao, Sergei P. Boudko, Andreas D. Kistler, Billy G. Hudson

J Biol Chem. 2021 Jan-Jun; 296: 100590. Published online 2021 Mar 26. doi: 10.1016/j.jbc.2021.100590

PMCID:: PMC8100070

Abstract Article PDF–5.4M

Select item 79308757.

A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome

Christoforos Odiatis, Isavella Savva, Myrtani Pieri, Pavlos Ioannou, Petros Petrou, Gregory Papagregoriou, Kyriaki Antoniadou, Neoklis Makrides, Charalambos Stefanou, Danica Galešić Ljubanović, Georgios Nikolaou, Dorin-Bogdan Borza, Kostas Stylianou, Oliver Gross, Constantinos Deltas

Matrix Biol Plus. 2021 Feb; 9: 100053. Published online 2020 Dec 30. doi: 10.1016/j.mbplus.2020.100053

PMCID:: PMC7930875

Abstract Article PDF–5.6M

Select item 74468198.

RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis

Brianna Dufek, Daniel T. Meehan, Duane Delimont, Kevin Wilhelm, Gina Samuelson, Ross Coenen, Jacob Madison, Edward Doyle, Brendan Smyth, Grady Phillips, Michael Anne Gratton, Dominic Cosgrove

PLoS One. 2020; 15(8): e0237907. Published online 2020 Aug 21. doi: 10.1371/journal.pone.0237907

PMCID:: PMC7446819

Abstract Article PDF–2.3M

Select item 70603239.

Angiotensin-[1–7] attenuates kidney injury in experimental Alport syndrome

Hong Sang Choi, In Jin Kim, Chang Seong Kim, Seong Kwon Ma, James W. Scholey, Soo Wan Kim, Eun Hui Bae

Sci Rep. 2020; 10: 4225. Published online 2020 Mar 6. doi: 10.1038/s41598-020-61250-5

PMCID:: PMC7060323

Abstract Article PDF–3.9M

Select item 669562210.

Olmesartan Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome by Suppressing Tubular Expression of TGFβ

Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, In Jin Kim, Seong Kwon Ma, James W. Scholey, Soo Wan Kim, Eun Hui Bae

Int J Mol Sci. 2019 Aug; 20(15): 3843. Published online 2019 Aug 6. doi: 10.3390/ijms20153843

PMCID:: PMC6695622

Abstract Article PDF–3.3M

Select item 519827911.

Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD–Related Systemic Inflammation

Kirstin Andersen, Marie Sophie Kesper, Julian A. Marschner, Lukas Konrad, Mi Ryu, Santhosh Kumar VR, Onkar P. Kulkarni, Shrikant R. Mulay, Simone Romoli, Jana Demleitner, Patrick Schiller, Alexander Dietrich, Susanna Müller, Oliver Gross, Hans-Joachim Ruscheweyh, Daniel H. Huson, Bärbel Stecher, Hans-Joachim Anders

J Am Soc Nephrol. 2017 Jan; 28(1): 76–83. Published online 2016 May 5. doi: 10.1681/ASN.2015111285

PMCID:: PMC5198279

Abstract Article

Select item 464071512.

Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment

Munkyung Kim, Alessandro Piaia, Neeta Shenoy, David Kagan, Berangere Gapp, Benjamin Kueng, Delphine Weber, William Dietrich, Iwona Ksiazek

PLoS One. 2015; 10(11): e0141231. Published online 2015 Nov 10. doi: 10.1371/journal.pone.0141231

PMCID:: PMC4640715

Abstract Article PDF–20M

Select item 331176913.

Murine membranous nephropathy: Immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome

Jun-Jun Zhang, Mahdi Malekpour, Wentian Luo, Linna Ge, Florina Olaru, Xu-Ping Wang, Maimouna Bah, Yoshikazu Sado, Laurence Heidet, Sandra Kleinau, Agnes B. Fogo, Dorin-Bogdan Borza

J Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: J Immunol. 2012 Apr 1; 188(7): 3268–3277. Published online 2012 Feb 27. doi: 10.4049/jimmunol.1103368

PMCID:: PMC3311769

Abstract Article PDF–3.3M

Select item 306396814.

Biophysical properties of normal and diseased renal glomeruli

Hans M. Wyss, Joel M. Henderson, Fitzroy J. Byfield, Leslie A. Bruggeman, Yaxian Ding, Chunfa Huang, Jung Hee Suh, Thomas Franke, Elisa Mele, Martin R. Pollak, Jeffrey H. Miner, Paul A. Janmey, David A. Weitz, R. Tyler Miller

Am J Physiol Cell Physiol. 2011 Mar; 300(3): C397–C405. Published online 2010 Dec 1. doi: 10.1152/ajpcell.00438.2010

PMCID:: PMC3063968

Abstract Article

Select item 270968215.

Cellular Origins of Type IV Collagen Networks in Developing Glomeruli

Dale R. Abrahamson, Billy G. Hudson, Larysa Stroganova, Dorin-Bogdan Borza, Patricia L. St. John

J Am Soc Nephrol. 2009 Jul; 20(7): 1471–1479. doi: 10.1681/ASN.2008101086

PMCID:: PMC2709682

Abstract Article

Select item 212107916.

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome

J Cell Biol. 1996 Dec 1; 135(5): 1403–1413. doi: 10.1083/jcb.135.5.1403

PMCID:: PMC2121079

Summary PDF–1.4M

Select item 160640017.

Matrix Metalloproteinase Dysregulation in the Stria Vascularis of Mice with Alport Syndrome : Implications for Capillary Basement Membrane Pathology

Michael Anne Gratton, Velidi H. Rao, Daniel T. Meehan, Charles Askew, Dominic Cosgrove

Am J Pathol. 2005 May; 166(5): 1465–1474. doi: 10.1016/S0002-9440(10)62363-2

PMCID:: PMC1606400

Abstract Article PDF–1.8M

Select item 922378518.

Col4a3^-/- Mice on Balb/C Background Have Less Severe Cardiorespiratory Phenotype and SGLT2 Over-Expression Compared to 129x1/SvJ and C57Bl/6 Backgrounds

Camila I. Irion, Monique Williams, Jose Condor Capcha, Trevor Eisenberg, Guerline Lambert, Lauro M. Takeuchi, Grace Seo, Keyvan Yousefi, Rosemeire Kanashiro-Takeuchi, Keith A. Webster, Karen C. Young, Joshua M. Hare, Lina A. Shehadeh

Int J Mol Sci. 2022 Jun; 23(12): 6674. Published online 2022 Jun 15. doi: 10.3390/ijms23126674

PMCID:: PMC9223785

Abstract Article PDF–7.7M

Select item 896388119.

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

Brian Czaya, Kylie Heitman, Isaac Campos, Christopher Yanucil, Dominik Kentrup, David Westbrook, Orlando Gutierrez, Jodie L Babitt, Grace Jung, Isidro B Salusky, Mark Hanudel, Christian Faul

eLife. 2022; 11: e74782. Published online 2022 Mar 18. doi: 10.7554/eLife.74782

PMCID:: PMC8963881

Abstract Article PDF–15M

Select item 658024720.

Endothelial cell-specific collagen type IV-α₃ expression does not rescue Alport syndrome in Col4a3⁻^/− mice

Steven D. Funk, Raymond H. Bayer, Jeffrey H. Miner

Am J Physiol Renal Physiol. 2019 May 1; 316(5): F830–F837. Published online 2019 Feb 6. doi: 10.1152/ajprenal.00556.2018

PMCID:: PMC6580247

Abstract Article

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