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Select item 107916991.

Ketosis prevents abdominal aortic aneurysm rupture through C–C chemokine receptor type 2 downregulation and enhanced extracellular matrix balance

Sergio Sastriques-Dunlop, Santiago Elizondo-Benedetto, Batool Arif, Rodrigo Meade, Mohamed S. Zaghloul, Hannah Luehmann, Gyu S. Heo, Sean J. English, Yongjian Liu, Mohamed A. Zayed

Sci Rep. 2024; 14: 1438. Published online 2024 Jan 16. doi: 10.1038/s41598-024-51996-7

PMCID:: PMC10791699

Article PDF–9.8M

Select item 103962982.

CCR2 is a host entry receptor for severe fever with thrombocytopenia syndrome virus

Leike Zhang, Xuefang Peng, Qingxing Wang, Jin Li, Shouming Lv, Shuo Han, Lingyu Zhang, Heng Ding, Cong-Yi Wang, Gengfu Xiao, Xuguang Du, Ke Peng, Hao Li, Wei Liu

Sci Adv. 2023 Aug; 9(31): eadg6856. Published online 2023 Aug 2. doi: 10.1126/sciadv.adg6856

PMCID:: PMC10396298

Article PDF–2.1M

Select item 102962903.

CC-Chemokine Receptor-2 Expression in Osteoblasts Contributes to Cartilage and Bone Damage during Post-Traumatic Osteoarthritis

Helen Willcockson, Huseyin Ozkan, José Valdés-Fernández, Liubov Arbeeva, Esra Mucahit, Layla Musawwir, Lola B. Hooper, Froilán Granero-Moltó, Felipe Prósper, Lara Longobardi

Biomolecules. 2023 Jun; 13(6): 891. Published online 2023 May 26. doi: 10.3390/biom13060891

PMCID:: PMC10296290

Article PDF–27M

Select item 102438184.

Reactive myelopoiesis and FX-expressing macrophages triggered by chemotherapy promote cancer lung metastasis

Caijun Wu, Qian Zhong, Rejeena Shrestha, Jingzhi Wang, Xiaoling Hu, Hong Li, Eric C. Rouchka, Jun Yan, Chuanlin Ding

JCI Insight. 2023 May 8; 8(9): e167499. Published online 2023 May 8. doi: 10.1172/jci.insight.167499

PMCID:: PMC10243818

Article PDF–9.9M

Select item 101276875.

Intragranuloma Accumulation and Inflammatory Differentiation of Neutrophils Underlie Mycobacterial ESX-1-Dependent Immunopathology

Julia Lienard, Kristina Munke, Line Wulff, Clément Da Silva, Julien Vandamme, Katie Laschanzky, Thorsten Joeris, William Agace, Fredric Carlsson

mBio. 2023 Mar-Apr; 14(2): e02764-22. Published online 2023 Apr 5. doi: 10.1128/mbio.02764-22

PMCID:: PMC10127687

Article PDF–3.7M

Select item 100798556.

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus

Carlos Alemán-Ruiz, Wenyi Wang, Ray Dingledine, Nicholas H. Varvel

Sci Rep. 2023; 13: 5651. Published online 2023 Apr 6. doi: 10.1038/s41598-023-32752-9

PMCID:: PMC10079855

Article PDF–4.9M

Select item 97975207.

Transcriptome profiling of osteoclast subsets associated with arthritis: A pathogenic role of CCR2^hi osteoclast progenitors

Maša Filipović, Darja Flegar, Sara Aničić, Dino Šisl, Tomislav Kelava, Nataša Kovačić, Alan Šućur, Danka Grčević

Front Immunol. 2022; 13: 994035. Published online 2022 Dec 15. doi: 10.3389/fimmu.2022.994035

PMCID:: PMC9797520

Article PDF–3.5M

Select item 96592558.

Absence of CCR2 Promotes Proliferation of Alveolar Macrophages That Control Lung Inflammation in Acute Respiratory Distress Syndrome in Mice

Vivian Louise Soares de Oliveira, Emilie Pollenus, Nele Berghmans, Celso Martins Queiroz-Junior, Marfa Blanter, Matheus Silvério Mattos, Mauro Martins Teixeira, Paul Proost, Philippe E. Van den Steen, Flávio Almeida Amaral, Sofie Struyf

Int J Mol Sci. 2022 Nov; 23(21): 12920. Published online 2022 Oct 26. doi: 10.3390/ijms232112920

PMCID:: PMC9659255

Article PDF–3.8M

Select item 95933149.

CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon-resident and circulating monocytes/macrophages

Samantha Muscat, Anne E. C. Nichols, Emma Gira, Alayna E. Loiselle

FASEB J. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: FASEB J. 2022 Nov; 36(11): e22607. doi: 10.1096/fj.202201162R

PMCID:: PMC9593314

Article PDF–1.3M

Select item 958390810.

Monocyte-derived peritoneal macrophages protect C57BL/6 mice against surgery-induced adhesions

Rinal Sahputra, Krittee Dejyong, Adrian S. Woolf, Matthias Mack, Judith E. Allen, Dominik Rückerl, Sarah E. Herrick

Front Immunol. 2022; 13: 1000491. Published online 2022 Oct 6. doi: 10.3389/fimmu.2022.1000491

PMCID:: PMC9583908

Article PDF–19M

Select item 934264211.

Myeloid CCR2 Promotes Atherosclerosis after AKI

Anne M. Hüsing, Vera C. Wulfmeyer, Svenja Gaedcke, Susanne V. Fleig, Song Rong, David DeLuca, Hermann Haller, Roland Schmitt, Sibylle von Vietinghoff

J Am Soc Nephrol. 2022 Aug; 33(8): 1487–1500. Published online 2022 Aug. doi: 10.1681/ASN.2022010048

PMCID:: PMC9342642

Article

Select item 885986412.

Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells

Alexandra L. McCubbrey, Shannon A. McManus, Jazalle D. McClendon, Stacey M. Thomas, Hope B. Chatwin, Julie A. Reisz, Angelo D’Alessandro, Kara J. Mould, Donna L. Bratton, Peter M. Henson, William J. Janssen

Cell Rep. Author manuscript; available in PMC 2022 Feb 21.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110222. doi: 10.1016/j.celrep.2021.110222

PMCID:: PMC8859864

Article PDF–1.6M

Select item 859493113.

CCR2 deficiency alters activation of microglia subsets in traumatic brain injury

Kerri Somebang, Joshua Rudolph, Isabella Imhof, Luyi Li, Erene C. Niemi, Judy Shigenaga, Huy Tran, T. Michael Gill, Iris Lo, Brian A. Zabel, Gabriela Schmajuk, Brian T. Wipke, Stefka Gyoneva, Luke Jandreski, Michael Craft, Gina Benedetto, Edward D. Plowey, Israel Charo, James Campbell, Chun Jimmie Ye, S. Scott Panter, Mary C. Nakamura, Walter Eckalbar, Christine L. Hsieh

Cell Rep. Author manuscript; available in PMC 2021 Nov 16.

Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109727. doi: 10.1016/j.celrep.2021.109727

PMCID:: PMC8594931

Article PDF–2.6M

Select item 857652814.

CCR2 Signaling Restricts SARS-CoV-2 Infection

Abigail Vanderheiden, Jeronay Thomas, Allison L. Soung, Meredith E. Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A. Cowan, Kathryn Pellegrini, Adrian Creanga, Amarendra Pegu, Alexandrine Derrien-Colemyn, Pei-Yong Shi, Arash Grakoui, Robyn S. Klein, Steven E. Bosinger, Jacob E. Kohlmeier, Vineet D. Menachery, Mehul S. Suthar

mBio. 2021 Nov-Dec; 12(6): e02749-21. Published online 2021 Nov 9. doi: 10.1128/mBio.02749-21

Correction in:: mBio. 2022 May-Jun; 13(3): e00259-22.

PMCID:: PMC8576528

Article PDF–4.2M

Select item 840633215.

CCR2 Signaling Promotes Brain Infiltration of Inflammatory Monocytes and Contributes to Neuropathology during Cryptococcal Meningoencephalitis

Jintao Xu, Anutosh Ganguly, Jessica Zhao, Michel Ivey, Rafael Lopez, John J. Osterholzer, Clifford S. Cho, Michal A. Olszewski

mBio. 2021 Jul-Aug; 12(4): e01076-21. Published online 2021 Jul 27. doi: 10.1128/mBio.01076-21

PMCID:: PMC8406332

Article PDF–5.0M

Select item 828758616.

CCR2 Deficiency Impairs Ly6C^lo and Ly6C^hi Monocyte Responses in Orientia tsutsugamushi Infection

Michael Petermann, Zacharias Orfanos, Julie Sellau, Mohammad Gharaibeh, Hannelore Lotter, Bernhard Fleischer, Christian Keller

Front Immunol. 2021; 12: 670219. Published online 2021 Jul 5. doi: 10.3389/fimmu.2021.670219

PMCID:: PMC8287586

Article PDF–4.0M

Select item 802534617.

The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice

Shingo Ishihara, Alia M. Obeidat, David L. Wokosin, Dongjun Ren, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller

Arthritis Res Ther. 2021; 23: 103. Published online 2021 Apr 7. doi: 10.1186/s13075-021-02486-y

PMCID:: PMC8025346

Article PDF–4.8M

Select item 792173618.

CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome

Emilie Pollenus, Thao-Thy Pham, Leen Vandermosten, Queeny Robalo, Hendrik Possemiers, Sofie Knoops, Ghislain Opdenakker, Philippe E. Van den Steen

Front Immunol. 2020; 11: 628643. Published online 2021 Feb 16. doi: 10.3389/fimmu.2020.628643

Correction in:: Front Immunol. 2022; 13: 926032.

PMCID:: PMC7921736

Article PDF–7.0M

Select item 785735419.

Macrophage Depletion in CCR2^−/− Mice Delays Bacterial Clearance and Enhances Neutrophil Infiltration in an Acute Otitis Media Model

Dong Gu Hur, Arwa Kurabi, Hyun Woo Lim, Meghan Spriggs, Kwang Pak, Allen F Ryan

J Infect Dis. 2021 Jan 15; 223(2): 333–341. Published online 2020 Jun 23. doi: 10.1093/infdis/jiaa353

PMCID:: PMC7857354

Article PDF–2.3M

Select item 779173620.

CCR2 improves homing and engraftment of adipose-derived stem cells in dystrophic mice

Liang Wang, Huan Li, Jinfu Lin, Ruojie He, Menglong Chen, Yu Zhang, Ziyu Liao, Cheng Zhang

Stem Cell Res Ther. 2021; 12: 12. Published online 2021 Jan 7. doi: 10.1186/s13287-020-02065-z

PMCID:: PMC7791736

Article PDF–12M

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