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Select item 91190071.

Cdk2 suppresses IL‐23 expression and the onset of severe acute pancreatitis

Yanpeng Ma, Longlong Liu, Bin Li, Wenyao Wang, Tingting Zhao

Immun Inflamm Dis. 2022 Jun; 10(6): e631. Published online 2022 May 19. doi: 10.1002/iid3.631

PMCID:: PMC9119007

Article PDF–1.0M

Select item 78820662.

CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent K_ATP channel closure

Sophia M. Sdao, Thuong Ho, Chetan Poudel, Hannah R. Foster, Elizabeth R. De Leon, Melissa T. Adams, Ji-Hyeon Lee, Barak Blum, Sushil G. Rane, Matthew J. Merrins

Cell Rep. Author manuscript; available in PMC 2021 Feb 14.

Published in final edited form as: Cell Rep. 2021 Jan 26; 34(4): 108690. doi: 10.1016/j.celrep.2021.108690

PMCID:: PMC7882066

Article PDF–1.5M

Select item 73556503.

Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2

Yan-Chen Liu, Na Feng, Wei-Wei Li, Peng-Fei Tu, Jian-Ping Chen, Jing-Yan Han, Ke-Wu Zeng

Molecules. 2020 Jun; 25(12): 2840. Published online 2020 Jun 19. doi: 10.3390/molecules25122840

PMCID:: PMC7355650

Article PDF–2.4M

Select item 71278674.

Cdk2 catalytic activity is essential for meiotic cell division in vivo

Sangeeta Chauhan, M. Kasim Diril, Joanna H.S. Lee, Xavier Bisteau, Vanessa Manoharan, Deepak Adhikari, Chandrahas Koumar Ratnacaram, Baptiste Janela, Juliane Noffke, Florent Ginhoux, Vincenzo Coppola, Kui Liu, Lino Tessarollo, Philipp Kaldis

Biochem J. Author manuscript; available in PMC 2020 Apr 4.

Published in final edited form as: Biochem J. 2016 Sep 15; 473(18): 2783–2798. Published online 2016 Jul 1. doi: 10.1042/BCJ20160607

PMCID:: PMC7127867

Article PDF–1.6M

Select item 68575895.

CDK2 kinase activity is a regulator of male germ cell fate

Priti Singh, Ravi K. Patel, Nathan Palmer, Jennifer K. Grenier, Darius Paduch, Philipp Kaldis, Andrew Grimson, John C. Schimenti

Development. 2019 Nov 1; 146(21): dev180273. Published online 2019 Nov 6. doi: 10.1242/dev.180273

PMCID:: PMC6857589

Article

Select item 58814716.

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss

Tal Teitz, Jie Fang, Asli N. Goktug, Justine D. Bonga, Shiyong Diao, Robert A. Hazlitt, Luigi Iconaru, Marie Morfouace, Duane Currier, Yinmei Zhou, Robyn A. Umans, Michael R. Taylor, Cheng Cheng, Jaeki Min, Burgess Freeman, Junmin Peng, Martine F. Roussel, Richard Kriwacki, R. Kiplin Guy, Taosheng Chen, Jian Zuo

J Exp Med. 2018 Apr 2; 215(4): 1187–1203. doi: 10.1084/jem.20172246

PMCID:: PMC5881471

Article PDF–2.6M

Select item 43809297.

T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes

Stephanie Mueller, Jérémy Huard, Katharina Waldow, Xiaoyun Huang, Lorenza A D'Alessandro, Sebastian Bohl, Kathleen Börner, Dirk Grimm, Steffen Klamt, Ursula Klingmüller, Marcel Schilling

Mol Syst Biol. 2015 Mar; 11(3): 0795. Published online 2015 Mar 14. doi: 10.15252/msb.20156032

PMCID:: PMC4380929

Article PDF–4.3M

Select item 39282878.

Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo

Eric A. Hanse, Christopher J. Nelsen, Melissa M. Goggin, Chelsea K. Anttila, Lisa K. Mullany, Cyril Berthet, Philipp Kaldis, Gretchen S. Crary, Ryoko Kuriyama, Jeffrey H. Albrecht

Cell Cycle. Author manuscript; available in PMC 2014 Feb 18.

Published in final edited form as: Cell Cycle. 2009 Sep 1; 8(17): 2802–2809. Published online 2009 Sep 8. doi: 10.4161/cc.8.17.9465

PMCID:: PMC3928287

Article PDF–719K

Select item 35186719.

Cyclin-dependent kinase 2 controls peripheral immune tolerance

Neelanjana Chunder, Liqing Wang, Chunxia Chen, Wayne W. Hancock, Andrew D. Wells

J Immunol. Author manuscript; available in PMC 2013 Dec 15.

Published in final edited form as: J Immunol. 2012 Dec 15; 189(12): 5659–5666. Published online 2012 Nov 7. doi: 10.4049/jimmunol.1202313

PMCID:: PMC3518671

Article PDF–2.2M

Select item 308027010.

Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system

Céline Caillava, Renaud Vandenbosch, Beata Jablonska, Cyrille Deboux, Giulia Spigoni, Vittorio Gallo, Brigitte Malgrange, Anne Baron-Van Evercooren

J Cell Biol. 2011 Apr 18; 193(2): 397–407. doi: 10.1083/jcb.201004146

PMCID:: PMC3080270

Article PDF–2.7M

Select item 285962011.

Cdk2 deficiency decrease ras/cdk4-dependent malignant progression, but not myc-induced tumorigenesis

Everardo Macias, Yongbaek Kim, Paula L. Miliani de Marval, Andres Klein-Szanto, Marcelo L. Rodriguez-Puebla

Cancer Res. Author manuscript; available in PMC 2010 Apr 26.

Published in final edited form as: Cancer Res. 2007 Oct 15; 67(20): 9713–9720. doi: 10.1158/0008-5472.CAN-07-2119

PMCID:: PMC2859620

Article PDF–1.9M

Select item 284420312.

Coupling of the Cell Cycle and Apoptotic Machineries in Developing T Cells

Ling Xue, Yuefang Sun, Leslie Chiang, Bo He, Chulho Kang, Hector Nolla, Astar Winoto

J Biol Chem. 2010 Mar 5; 285(10): 7556–7565. Published online 2010 Jan 12. doi: 10.1074/jbc.M109.035535

PMCID:: PMC2844203

Article PDF–4.5M

Select item 247578913.

CDK2 Activation in Mouse Epidermis Induces Keratinocyte Proliferation but Does Not Affect Skin Tumor Development

Everardo Macias, Paula L. Miliani de Marval, Adriana De Siervi, Claudio J. Conti, Adrian M. Senderowicz, Marcelo L. Rodriguez-Puebla

Am J Pathol. 2008 Aug; 173(2): 526–535. doi: 10.2353/ajpath.2008.071124

PMCID:: PMC2475789

Article PDF–1.5M

Select item 222559614.

Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication

Anette Duensing, Ying Liu, Michelle Tseng, Marcos Malumbres, Mariano Barbacid, Stefan Duensing

Oncogene. Author manuscript; available in PMC 2008 Feb 4.

Published in final edited form as: Oncogene. 2006 May 11; 25(20): 2943–2949. doi: 10.1038/sj.onc.1209310

PMCID:: PMC2225596

Article PDF–689K

Select item 219304015.

The Cyclin-dependent Kinase Cdk2 Regulates Thymocyte Apoptosis

Anne Hakem, Takehiko Sasaki, Ivona Kozieradzki, Josef M. Penninger

J Exp Med. 1999 Mar 15; 189(6): 957–968. doi: 10.1084/jem.189.6.957

PMCID:: PMC2193040

Article PDF–343K

Select item 214004416.

Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zone

Beata Jablonska, Adan Aguirre, Renaud Vandenbosch, Shibeshih Belachew, Cyril Berthet, Philipp Kaldis, Vittorio Gallo

J Cell Biol. 2007 Dec 17; 179(6): 1231–1245. doi: 10.1083/jcb.200702031

PMCID:: PMC2140044

Article PDF–4.3M

Select item 195195217.

Hematopoiesis and Thymic Apoptosis Are Not Affected by the Loss of Cdk2

Cyril Berthet, Maria Cecilia Rodriguez-Galan, Deborah L. Hodge, John Gooya, Véronique Pascal, Howard A. Young, Jonathan Keller, Remy Bosselut, Philipp Kaldis

Mol Cell Biol. 2007 Jul; 27(14): 5079–5089. Published online 2007 May 7. doi: 10.1128/MCB.00029-07

PMCID:: PMC1951952

Article PDF–947K

Select item 1089730418.

Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy

Xue Chen, Ying Wang, Jia-Nan Wang, Yi-Chen Zhang, Ye-Ran Zhang, Ru-Xu Sun, Bing Qin, Yuan-Xin Dai, Hong-Jing Zhu, Jin-Xiang Zhao, Wei-Wei Zhang, Jiang-Dong Ji, Song-Tao Yuan, Qun-Dong Shen, Qing-Huai Liu

EMBO Mol Med. 2024 Feb; 16(2): 294–318. Published online 2024 Jan 31. doi: 10.1038/s44321-024-00025-1

PMCID:: PMC10897304

Article PDF–6.8M

Select item 1044980419.

Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice

Julia Otto, Anna Verwaayen, Christian Penners, Jana Hundertmark, Cheng Lin, Carina Kallen, Daniela Paffen, Tobias Otto, Hilmar Berger, Frank Tacke, Ralf Weiskirchen, Yulia A. Nevzorova, Matthias Bartneck, Christian Trautwein, Roland Sonntag, Christian Liedtke

Cell Death Dis. 2023 Aug; 14(8): 549. Published online 2023 Aug 24. doi: 10.1038/s41419-023-06077-4

PMCID:: PMC10449804

Article PDF–12M

Select item 858411220.

Regulation of p27 and Cdk2 Expression in Different Adipose Tissue Depots in Aging and Obesity

Ignacio Colón-Mesa, Marta Fernández-Galilea, Neira Sáinz, Marta Lopez-Yus, Jose M. Artigas, José Miguel Arbonés-Mainar, Elisa Félix-Soriano, Xavier Escoté, María Jesús Moreno-Aliaga

Int J Mol Sci. 2021 Nov; 22(21): 11745. Published online 2021 Oct 29. doi: 10.3390/ijms222111745