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Select item 82042521.

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity

Vanessa Aires, Claire Coulon-Bainier, Anto Pavlovic, Martin Ebeling, Roland Schmucki, Christophe Schweitzer, Erich Kueng, Simon Gutbier, Eva Harde

Front Immunol. 2021; 12: 684430. Published online 2021 Jun 1. doi: 10.3389/fimmu.2021.684430

PMCID:: PMC8204252

Article PDF–5.2M

Select item 71798362.

The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection

Vitor E. Fernandes, Giuseppe Ercoli, Alan Bénard, Carolin Brandl, Hannah Fahnenstiel, Jennifer Müller-Winkler, Georg F. Weber, Paul Denny, Lars Nitschke, Peter W. Andrew

PLoS Pathog. 2020 Apr; 16(4): e1008464. Published online 2020 Apr 23. doi: 10.1371/journal.ppat.1008464

PMCID:: PMC7179836

Article PDF–3.8M

Select item 65741193.

CD22 blockade restores homeostatic microglial phagocytosis in aging brains

John V. Pluvinage, Michael S. Haney, Benjamin A. H. Smith, Jerry Sun, Tal Iram, Liana Bonanno, Lulin Li, Davis P. Lee, David W. Morgens, Andrew C. Yang, Steven R. Shuken, David Gate, Madeleine Scott, Purvesh Khatri, Jian Luo, Carolyn R. Bertozzi, Michael C. Bassik, Tony Wyss-Coray

Nature. Author manuscript; available in PMC 2019 Oct 3.

Published in final edited form as: Nature. 2019 Apr; 568(7751): 187–192. Published online 2019 Apr 3. doi: 10.1038/s41586-019-1088-4

PMCID:: PMC6574119

Article PDF–5.3M

Select item 59170774.

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

Naoko Matsubara, Akihiro Imamura, Tatsuya Yonemizu, Chizuru Akatsu, Hongrui Yang, Akiharu Ueki, Natsuki Watanabe, Hajjaj Abdu-Allah, Nobutaka Numoto, Hiromu Takematsu, Shinobu Kitazume, Thomas F. Tedder, Jamey D. Marth, Nobutoshi Ito, Hiromune Ando, Hideharu Ishida, Makoto Kiso, Takeshi Tsubata

Front Immunol. 2018; 9: 820. Published online 2018 Apr 19. doi: 10.3389/fimmu.2018.00820

PMCID:: PMC5917077

Article PDF–6.2M

Select item 53678135.

CD22 is required for formation of memory B cell precursors within germinal centers

Craig P. Chappell, Kevin E. Draves, Edward A. Clark

PLoS One. 2017; 12(3): e0174661. Published online 2017 Mar 27. doi: 10.1371/journal.pone.0174661

PMCID:: PMC5367813

Article PDF–1.2M

Select item 37739346.

CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions

Hiroko Nakashima, Yasuhito Hamaguchi, Rei Watanabe, Nobuko Ishiura, Yoshihiro Kuwano, Hitoshi Okochi, Yoshimasa Takahashi, Kunihiko Tamaki, Shinichi Sato, Thomas F. Tedder, Manabu Fujimoto

J Immunol. Author manuscript; available in PMC 2013 Sep 16.

Published in final edited form as: J Immunol. 2010 May 1; 184(9): 4637–4645. Published online 2010 Mar 24. doi: 10.4049/jimmunol.0901719

PMCID:: PMC3773934

Article PDF–4.2M

Select item 37250547.

CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca²⁺ signaling

Jennifer Müller, Ingrid Obermeier, Miriam Wöhner, Carolin Brandl, Sarah Mrotzek, Sieglinde Angermüller, Palash C. Maity, Michael Reth, Lars Nitschke

Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30): 12402–12407. Published online 2013 Jul 8. doi: 10.1073/pnas.1304888110

PMCID:: PMC3725054

Article PDF–921K

Select item 32629618.

The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia

Ting Wen, Melissa K. Mingler, Carine Blanchard, Benjamin Wahl, Oliver Pabst, Marc E. Rothenberg

J Immunol. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: J Immunol. 2012 Feb 1; 188(3): 1075–1082. Published online 2011 Dec 21. doi: 10.4049/jimmunol.1102222

PMCID:: PMC3262961

Article PDF–1.6M

Select item 28598879.

Differential expression of CD22 (Lyb8) on murine B cells

Loren D. Erickson, Lorraine T. Tygrett, Sudershan K. Bhatia, Kenneth H. Grabstein, Thomas J. Waldschmidt

Int Immunol. Author manuscript; available in PMC 2010 Apr 26.

Published in final edited form as: Int Immunol. 1996 Jul; 8(7): 1121–1129. doi: 10.1093/intimm/8.7.1121

PMCID:: PMC2859887

Article PDF–1.7M

Select item 219370210.

Sialic Acid Binding Domains of CD22 Are Required For Negative Regulation of B Cell Receptor Signaling

Lei Jin, Paul A. McLean, Benjamin G. Neel, Henry H. Wortis

J Exp Med. 2002 May 6; 195(9): 1199–1205. doi: 10.1084/jem.20011796

PMCID:: PMC2193702

Article PDF–111K

Select item 219305911.

Identification of CD22 Ligands on Bone Marrow Sinusoidal Endothelium Implicated in CD22-dependent Homing of Recirculating B Cells

Lars Nitschke, Helen Floyd, David J.P. Ferguson, Paul R. Crocker

J Exp Med. 1999 May 3; 189(9): 1513–1518. doi: 10.1084/jem.189.9.1513

PMCID:: PMC2193059

Article PDF–208K

Select item 219303412.

Deficiency in CD22, a B Cell–specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies

Theresa L. O'Keefe, Gareth T. Williams, Facundo D. Batista, Michael S. Neuberger

J Exp Med. 1999 Apr 19; 189(8): 1307–1313. doi: 10.1084/jem.189.8.1307

PMCID:: PMC2193034

Article PDF–125K

Select item 211854713.

Thromboxane A₂ is a key regulator of pathogenesis during Trypanosoma cruzi infection

Anthony W. Ashton, Shankar Mukherjee, FNU Nagajyothi, Huan Huang, Vicki L. Braunstein, Mahalia S. Desruisseaux, Stephen M. Factor, Lillie Lopez, Joan W. Berman, Murray Wittner, Philipp E. Scherer, Valerie Capra, Thomas M. Coffman, Charles N. Serhan, Katherine Gotlinger, Kenneth K. Wu, Louis M. Weiss, Herbert B. Tanowitz

J Exp Med. 2007 Apr 16; 204(4): 929–940. doi: 10.1084/jem.20062432

PMCID:: PMC2118547

Article PDF–3.3M

Select item 211853414.

Enhancement and suppression of signaling by the conserved tail of IgG memory–type B cell antigen receptors

Keisuke Horikawa, Stephen W. Martin, Sarah L. Pogue, Karlee Silver, Kaiman Peng, Kiyoshi Takatsu, Christopher C. Goodnow

J Exp Med. 2007 Apr 16; 204(4): 759–769. doi: 10.1084/jem.20061923

PMCID:: PMC2118534

Article PDF–3.3M

Select item 39593015.

Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact

Brian E. Collins, Ola Blixt, Alexis R. DeSieno, Nicolai Bovin, Jamey D. Marth, James C. Paulson

Proc Natl Acad Sci U S A. 2004 Apr 20; 101(16): 6104–6109. Published online 2004 Apr 12. doi: 10.1073/pnas.0400851101

PMCID:: PMC395930

Article PDF–514K

Select item 711684216.

A CD22-Shp1 phosphatase axis controls integrin β₇ display and B cell function in mucosal immunity

Romain Ballet, Martin Brennan, Carolin Brandl, Ningguo Feng, Jeremy Berri, Julian Cheng, Borja Ocón, Amin Alborzian Deh Sheikh, Alex Marki, Yuhan Bi, Clare L. Abram, Clifford A. Lowell, Takeshi Tsubata, Harry B. Greenberg, Matthew S. Macauley, Klaus Ley, Lars Nitschke, Eugene C. Butcher

Nat Immunol. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Nat Immunol. 2021 Mar 1; 22(3): 381–390. Published online 2021 Feb 15. doi: 10.1038/s41590-021-00862-z

PMCID:: PMC7116842

Article PDF–4.7M

Select item 645830717.

N-Linked Glycosylation Regulates CD22 Organization and Function

Laabiah Wasim, Fathima Hifza Mohamed Buhari, Myuran Yoganathan, Taylor Sicard, June Ereño-Orbea, Jean-Philippe Julien, Bebhinn Treanor

Front Immunol. 2019; 10: 699. Published online 2019 Apr 4. doi: 10.3389/fimmu.2019.00699

PMCID:: PMC6458307

Article PDF–5.3M

Select item 617312918.

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

Edward A. Clark, Natalia V. Giltiay

Front Immunol. 2018; 9: 2235. Published online 2018 Sep 28. doi: 10.3389/fimmu.2018.02235

PMCID:: PMC6173129

Article PDF–1011K

Select item 582158419.

CD22 promotes B-1b cell responses to T cell-independent type 2 antigens

Karen M. Haas, Kristen L. Johnson, James P. Phipps, Cardinal Do

J Immunol. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: J Immunol. 2018 Mar 1; 200(5): 1671–1681. Published online 2018 Jan 26. doi: 10.4049/jimmunol.1701578

PMCID:: PMC5821584

Article PDF–767K

Select item 470597120.

Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man

Matthew S. Macauley, Norihito Kawasaki, Wenjie Peng, Shui-Hua Wang, Yuan He, Britni M. Arlian, Ryan McBride, Reiji Kannagi, Kay-Hooi Khoo, James C. Paulson

J Biol Chem. 2015 Dec 11; 290(50): 30066–30077. Published online 2015 Oct 27. doi: 10.1074/jbc.M115.691337

PMCID:: PMC4705971

Article PDF–3.5M

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