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Select item 107924311.

CCK2-receptor deficiency impairs immune balance by influencing CD4⁺ T cells development by inhibiting cortical-thymic-epithelial-cells

Dong Zhang, Miaomiao Jia, Chuan Wang, Yingmin Li, Chunling Ma, Guiyun Zhu, Rufei Ma, Di Wen, Xianxian Jia, Guangming Xu, Xiaojing Zhang, Bin Cong

Exp Biol Med (Maywood) 2023 Oct; 248(20): 1718–1731. Published online 2023 Oct 3. doi: 10.1177/15353702231198083

PMCID:: PMC10792431

Article PDF–2.6M

Select item 67588562.

Deletion of CCK₂ Receptor in Mice Results in an Upregulation of the Endogenous Opioid System

Blandine Pommier, Françoise Beslot, Axelle Simon, Matthieu Pophillat, Toshimitsu Matsui, Valérie Dauge, Bernard P. Roques, Florence Noble

J Neurosci. 2002 Mar 1; 22(5): 2005–2011. doi: 10.1523/JNEUROSCI.22-05-02005.2002

PMCID:: PMC6758856

Article PDF–169K

Select item 67219793.

Targeting CCK2R for pancreatic cancer chemoprevention

Altaf Mohammed, Naveena B Janakiram, Chen Suen, Nicole Stratton, Stanley Lightfoot, Anil Singh, Gopal Pathuri, Rebekah Ritchie, Venkateshwar Madka, Chinthalapally V Rao

Mol Carcinog. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Mol Carcinog. 2019 Oct; 58(10): 1908–1918. Published online 2019 Jul 16. doi: 10.1002/mc.23084

PMCID:: PMC6721979

Article PDF–1.4M

Select item 66052994.

VGluT3-Expressing CCK-Positive Basket Cells Construct Invaginating Synapses Enriched with Endocannabinoid Signaling Proteins in Particular Cortical and Cortex-Like Amygdaloid Regions of Mouse Brains

Yuki Omiya, Motokazu Uchigashima, Kohtarou Konno, Miwako Yamasaki, Taisuke Miyazaki, Takayuki Yoshida, Ichiro Kusumi, Masahiko Watanabe

J Neurosci. 2015 Mar 11; 35(10): 4215–4228. doi: 10.1523/JNEUROSCI.4681-14.2015

PMCID:: PMC6605299

Article PDF–7.9M

Select item 53521125.

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus

Yoomi Lee, Aleksandra M. Urbanska, Yoku Hayakawa, Hongshan Wang, Andrew S. Au, Aesis M. Luna, Wenju Chang, Guangchun Jin, Govind Bhagat, Julian A. Abrams, Richard A. Friedman, Andrea Varro, Kenneth K. Wang, Malcolm Boyce, Anil K. Rustgi, Antonia R. Sepulveda, Michael Quante, Timothy C. Wang

Oncotarget. 2017 Jan 3; 8(1): 203–214. Published online 2016 Jul 18. doi: 10.18632/oncotarget.10667

PMCID:: PMC5352112

Article PDF–7.7M

Select item 41256366.

Mechanism for Src activation by the CCK2 receptor: Patho-physiological functions of this receptor in pancreas

Audrey Ferrand, Sebastien Vatinel, Aline Kowalski-Chauvel, Claudine Bertrand, Chantal Escrieut, Daniel Fourmy, Marlene Dufresne, Catherine Seva

World J Gastroenterol. 2006 Jul 28; 12(28): 4498–4503. Published online 2006 Jul 28. doi: 10.3748/wjg.v12.i28.4498

PMCID:: PMC4125636

Article PDF–929K

Select item 38310547.

Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice

Pawel Lisowski, Grzegorz R Juszczak, Joanna Goscik, Adrian M Stankiewicz, Marek Wieczorek, Lech Zwierzchowski, Artur H Swiergiel

BMC Neurosci. 2013; 14: 144. Published online 2013 Nov 13. doi: 10.1186/1471-2202-14-144

PMCID:: PMC3831054

Article PDF–430K

Select item 38297148.

Progastrin Stimulates Colonic Cell Proliferation via CCK2R- and β-Arrestin–Dependent Suppression of BMP2

Guangchun Jin, C. Benedikt Westphalen, Yoku Hayakawa, Daniel L. Worthley, Samuel Asfaha, Xiangdong Yang, Xiaowei Chen, Yiling Si, Hongshan Wang, Yagnesh Tailor, Richard A. Friedman, Timothy C. Wang

Gastroenterology. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Gastroenterology. 2013 Oct; 145(4): 10.1053/j.gastro.2013.07.034. Published online 2013 Jul 25. doi: 10.1053/j.gastro.2013.07.034

PMCID:: PMC3829714

Article PDF–1.8M

Select item 36803199.

A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples

Verity F Oliver, Jun Wan, Saurabh Agarwal, Donald J Zack, Jiang Qian, Shannath L Merbs

Epigenetics Chromatin. 2013; 6: 17. Published online 2013 Jun 7. doi: 10.1186/1756-8935-6-17

PMCID:: PMC3680319

Article PDF–1.2M

Select item 363168510.

Temporal association of elevated cholecystokininergic tone and adolescent trauma is critical for posttraumatic stress disorder-like behavior in adult mice

Anu Joseph, Mingxi Tang, Takayoshi Mamiya, Qian Chen, Ling-Ling Yang, Jianwei Jiao, Na Yu, Ya-Ping Tang

Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16): 6589–6594. Published online 2013 Apr 1. doi: 10.1073/pnas.1219601110

PMCID:: PMC3631685

Article PDF–1.2M

Select item 326975311.

Candidate Genes in Ocular Dominance Plasticity

M. Liset Rietman, J.-P. Sommeijer, Neuro-Bsik Mouse Phenomics Consortium, Christiaan N. Levelt, J. Alexander Heimel

Front Neurosci. 2012; 6: 11. Published online 2012 Feb 1. doi: 10.3389/fnins.2012.00011

PMCID:: PMC3269753

Article PDF–602K

Select item 301273312.

Bi-Directional Effect of Cholecystokinin Receptor-2 Overexpression on Stress-Triggered Fear Memory and Anxiety in the Mouse

Qian Chen, Mingxi Tang, Takayoshi Mamiya, Heh-In Im, Xiaoli Xiong, Anu Joseph, Ya-Ping Tang

PLoS One. 2010; 5(12): e15999. Published online 2010 Dec 30. doi: 10.1371/journal.pone.0015999

PMCID:: PMC3012733

Article PDF–890K

Select item 273592713.

Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice

Guangchun Jin, Vigneshwaran Ramanathan, Michael Quante, Gwang Ho Baik, Xiangdong Yang, Sophie S.W. Wang, Shuiping Tu, Shanisha A.K. Gordon, David Mark Pritchard, Andrea Varro, Arthur Shulkes, Timothy C. Wang

J Clin Invest. 2009 Sep 1; 119(9): 2691–2701. Published online 2009 Aug 3. doi: 10.1172/JCI38918

PMCID:: PMC2735927

Article PDF–5.0M

Select item 189081414.

Interpretation of knockout experiments: the congenic footprint

L C Schalkwyk, C Fernandes, M W Nash, K Kurrikoff, E Vasar, S Kõks

Genes Brain Behav. 2007 Apr 1; 6(3): 299–303. doi: 10.1111/j.1601-183X.2007.00304.x

PMCID:: PMC1890814

Article PDF–289K

Select item 138365215.

Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse

Qian Chen, Akira Nakajima, Corbin Meacham, Ya-Ping Tang

Proc Natl Acad Sci U S A. 2006 Mar 7; 103(10): 3881–3886. Published online 2006 Feb 28. doi: 10.1073/pnas.0505407103

PMCID:: PMC1383652

Article PDF–826K

Select item 1071712316.

Gastric acid secretion in cholecystokinin-1 receptor, -2 receptor, and -1, -2 receptor gene knockout mice

Setsuko Kanai, Hiroko Hosoya, Saeko Akimoto, Minoru Ohta, Toshimitsu Matsui, Soichi Takiguchi, Akihiro Funakoshi, Kyoko Miyasaka

J Physiol Sci. 2009 Jan; 59(1): 23–29. Published online 2008 Nov 30. doi: 10.1007/s12576-008-0001-y

PMCID:: PMC10717123

Article PDF–288K

Select item 927871617.

Intestinal Gastrin/CCKBR (Cholecystokinin B Receptor) Ameliorates Salt-Sensitive Hypertension by Inhibiting Intestinal Na⁺/H⁺ Exchanger 3 Activity Through a PKC (Protein Kinase C)-Mediated NHERF1 and NHERF2 Pathway

Xiaoliang Jiang, Yunpeng Liu, Xin-Yang Zhang, Xue Liu, Xing Liu, Xianxian Wu, Pedro A. Jose, Shun Duan, Fu-Jian Xu, Zhiwei Yang

Hypertension. 2022 Aug; 79(8): 1668–1679. Published online 2022 Jun 8. doi: 10.1161/HYPERTENSIONAHA.121.18791

PMCID:: PMC9278716

Article PDF–2.0M

Select item 726000118.

Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin

Jonathan N. Flak, Paulette B. Goforth, James Dell’Orco, Paul V. Sabatini, Chien Li, Nadejda Bozadjieva, Matthew Sorensen, Alec Valenta, Alan Rupp, Alison H. Affinati, Corentin Cras-Méneur, Ahsan Ansari, Jamie Sacksner, Nandan Kodur, Darleen A. Sandoval, Robert T. Kennedy, David P. Olson, Martin G. Myers, Jr.

J Clin Invest. 2020 Jun 1; 130(6): 2943–2952. Published online 2020 May 4. doi: 10.1172/JCI134135