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Select item 107940671.

Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS

Daniel C Akuma, Kimberly A Wodzanowski, Ronit Schwartz Wertman, Patrick M Exconde, Víctor R Vázquez Marrero, Chukwuma E Odunze, Daniel Grubaugh, Sunny Shin, Cornelius Taabazuing, Igor E Brodsky

eLife. 2024; 13: e83725. Published online 2024 Jan 17. doi: 10.7554/eLife.83725

PMCID:: PMC10794067

Article PDF–5.4M

Select item 104128052.

Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme

Amy H Chan, Sabrina S Burgener, Kassandra Vezyrgiannis, Xiaohui Wang, Jadie Acklam, Jessica B Von Pein, Malvina Pizzuto, Larisa I Labzin, Dave Boucher, Kate Schroder

Life Sci Alliance. 2023 Oct; 6(10): e202301908. Published online 2023 Aug 9. doi: 10.26508/lsa.202301908

PMCID:: PMC10412805

Article PDF–1.8M

Select item 99093533.

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

Charles Drummer, IV, Fatma Saaoud, Nirag C. Jhala, Ramon Cueto, Yu Sun, Keman Xu, Ying Shao, Yifan Lu, Huimin Shen, Ling Yang, Yan Zhou, Jun Yu, Sheng Wu, Nathaniel W. Snyder, Wenhui Hu, Jia ‘Joe’ Zhuo, Yinghui Zhong, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

Front Immunol. 2023; 14: 1113883. Published online 2023 Jan 26. doi: 10.3389/fimmu.2023.1113883

PMCID:: PMC9909353

Article PDF–12M

Select item 83271784.

Mechanical Ventilation Exacerbates Poly (I:C) Induced Acute Lung Injury: Central Role for Caspase-11 and Gut-Lung Axis

Shuqing Jin, Xibing Ding, Chenxuan Yang, Wenbo Li, Meihong Deng, Hong Liao, Xin Lv, Bruce R. Pitt, Timothy R. Billiar, Li-Ming Zhang, Quan Li

Front Immunol. 2021; 12: 693874. Published online 2021 Jul 19. doi: 10.3389/fimmu.2021.693874

PMCID:: PMC8327178

Article PDF–4.0M

Select item 82610175.

Caspase-11–Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis

Yingwei Zhu, Han Zhao, Jian Lu, Kai Lin, Jingbin Ni, Gaojue Wu, Hong Tang

Cell Mol Gastroenterol Hepatol. 2021; 12(2): 653–664. Published online 2021 Apr 21. doi: 10.1016/j.jcmgh.2021.04.009

PMCID:: PMC8261017

Article PDF–3.6M

Select item 70441936.

Caspase-11 promotes allergic airway inflammation

Zbigniew Zasłona, Ewelina Flis, Mieszko M. Wilk, Richard G. Carroll, Eva M. Palsson-McDermott, Mark M. Hughes, Ciana Diskin, Kathy Banahan, Dylan G. Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Gunter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J. McElvaney, Kingston H. G. Mills, Ed C. Lavelle, Małgorzata Wygrecka, Emma M. Creagh, Luke A. J. O’Neill

Nat Commun. 2020; 11: 1055. Published online 2020 Feb 26. doi: 10.1038/s41467-020-14945-2

PMCID:: PMC7044193

Article PDF–2.1M

Select item 67412457.

Dissociation between Neurodegeneration and Caspase-11-Mediated Activation of Caspase-1 and Caspase-3 in a Mouse Model of Amyotrophic Lateral Sclerosis

Shin Jung Kang, Ivelisse Sanchez, Naisen Jing, Junying Yuan

J Neurosci. 2003 Jul 2; 23(13): 5455–5460. doi: 10.1523/JNEUROSCI.23-13-05455.2003

PMCID:: PMC6741245

Article PDF–308K

Select item 67304108.

Caspase-11 Mediates Inflammatory Dopaminergic Cell Death in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson's Disease

Tsuyoshi Furuya, Hideki Hayakawa, Masanori Yamada, Kenji Yoshimi, Shin Hisahara, Masayuki Miura, Yoshikuni Mizuno, Hideki Mochizuki

J Neurosci. 2004 Feb 25; 24(8): 1865–1872. doi: 10.1523/JNEUROSCI.3309-03.2004

PMCID:: PMC6730410

Article PDF–728K

Select item 66527779.

Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice

John Allen, IV, Clare E. Gyorke, Manoj K. Tripathy, Yugen Zhang, Angela Lovett, Stephanie A. Montgomery, Uma M. Nagarajan

Infect Immun. 2019 Aug; 87(8): e00262-19. Prepublished online 2019 Jun 3. Published online 2019 Jul 23. doi: 10.1128/IAI.00262-19

PMCID:: PMC6652777

Article PDF–937K

Select item 653100410.

cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

Ruochan Chen, Ling Zeng, Shan Zhu, Jiao Liu, Herbert J. Zeh, Guido Kroemer, Haichao Wang, Timothy R. Billiar, Jianxin Jiang, Daolin Tang, Rui Kang

Sci Adv. 2019 May; 5(5): eaav5562. Published online 2019 May 22. doi: 10.1126/sciadv.aav5562

PMCID:: PMC6531004

Article PDF–783K

Select item 615249511.

CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection

Kathrin Krause, Kyle Caution, Asmaa Badr, Kaitlin Hamilton, Abdulmuti Saleh, Khushbu Patel, Stephanie Seveau, Luanne Hall-Stoodley, Rana Hegazi, Xiaoli Zhang, Mikhail A. Gavrilin, Amal O. Amer

Autophagy. 2018; 14(11): 1928–1942. Published online 2018 Aug 31. doi: 10.1080/15548627.2018.1491494

PMCID:: PMC6152495

Article PDF–2.7M

Select item 612296812.

Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation

Bettina L. Lee, Irma B. Stowe, Aaron Gupta, Opher S. Kornfeld, Merone Roose-Girma, Keith Anderson, Søren Warming, Juan Zhang, Wyne P. Lee, Nobuhiko Kayagaki

J Exp Med. 2018 Sep 3; 215(9): 2279–2288. doi: 10.1084/jem.20180589

PMCID:: PMC6122968

Article PDF–1.5M

Select item 588261413.

Stearoyl lysophosphatidylcholine inhibits endotoxin-induced caspase-11 activation

Wenbo Li, Wei Zhang, Meihong Deng, Patricia Loughran, Yiting Tang, Hong Liao, Xianying Zhang, Jian Liu, Timothy R. Billiar, Ben Lu

Shock. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Shock. 2018 Sep; 50(3): 339–345. doi: 10.1097/SHK.0000000000001012

PMCID:: PMC5882614

Article PDF–1.3M

Select item 573359714.

The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages

Padmaja Jakka, Swapna Namani, Subathra Murugan, Nivedita Rai, Girish Radhakrishnan

J Biol Chem. 2017 Dec 15; 292(50): 20613–20627. Published online 2017 Oct 23. doi: 10.1074/jbc.M117.815878

PMCID:: PMC5733597

Article PDF–2.7M

Select item 560740815.

Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection

Wei Wang, Yue Shao, Shengjun Li, Na Xin, Tingxian Ma, Chenghai Zhao, Min Song

Infect Immun. 2017 Oct; 85(10): e00350-17. Prepublished online 2017 Jul 31. Published online 2017 Sep 20. doi: 10.1128/IAI.00350-17

PMCID:: PMC5607408

Article PDF–1.8M

Select item 487492216.

Bacterial outer membrane vesicles mediate cytosolic localization of LPS and caspase-11 activation

Sivapriya Kailasan Vanaja, Ashley J. Russo, Bharat Behl, Ishita Banerjee, Maya Yankova, Sachin D. Deshmukh, Vijay A.K. Rathinam

Cell. Author manuscript; available in PMC 2017 May 19.

Published in final edited form as: Cell. 2016 May 19; 165(5): 1106–1119. Published online 2016 May 5. doi: 10.1016/j.cell.2016.04.015

PMCID:: PMC4874922

Article PDF–2.6M

Select item 447566517.

Cutting Edge: Caspase-11 limits the response of CD8⁺ T cells to low abundance and low affinity antigens

Tessa Bergsbaken, Michael J. Bevan

J Immunol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Immunol. 2015 Jul 1; 195(1): 41–45. Published online 2015 May 15. doi: 10.4049/jimmunol.1500812

PMCID:: PMC4475665

Article PDF–976K

Select item 439907718.

Induction of Caspase-11 by Aspartyl Proteinases of Candida albicans and Implication in Promoting Inflammatory Response

Elena Gabrielli, Eva Pericolini, Eugenio Luciano, Samuele Sabbatini, Elena Roselletti, Stefano Perito, Lydia Kasper, Bernhard Hube, Anna Vecchiarelli

Infect Immun. 2015 May; 83(5): 1940–1948. Prepublished online 2015 Feb 23. Published online 2015 Apr 15. doi: 10.1128/IAI.02895-14

PMCID:: PMC4399077

Article PDF–1.6M

Select item 429812519.

Protective Role for Caspase-11 during Acute Experimental Murine Colitis

Katarzyna Oficjalska, Mathilde Raverdeau, Gabriella Aviello, Siobhan C. Wade, Ana Hickey, Katherine M. Sheehan, Sinead C. Corr, Elaine W. Kay, Luke A. O’Neill, Kingston H. G. Mills, Emma M. Creagh

J Immunol. 2015 Feb 1; 194(3): 1252–1260. Published online 2014 Dec 29. doi: 10.4049/jimmunol.1400501

PMCID:: PMC4298125

Article PDF–1.6M

Select item 429785520.

Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis

Tere M. Williams, Rachel A. Leeth, Daniel E. Rothschild, Dylan K. McDaniel, Sheryl L. Coutermarsh-Ott, Alysha E. Simmons, Kye H. Kable, Bettina Heid, Irving C. Allen

Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15; 308(2): G139–G150. Published online 2014 Nov 20. doi: 10.1152/ajpgi.00234.2014