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Select item 89831411.

The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice

Aidan W. Porter, Diep N. Nguyen, Dennis R. Clayton, Wily G. Ruiz, Stephanie M. Mutchler, Evan C. Ray, Allison L. Marciszyn, Lubika J. Nkashama, Arohan R. Subramanya, Sebastien Gingras, Thomas R. Kleyman, Gerard Apodaca, Linda M. Hendershot, Jeffrey L. Brodsky, Teresa M. Buck

JCI Insight. 2022 Mar 8; 7(5): e151869. Published online 2022 Mar 8. doi: 10.1172/jci.insight.151869

PMCID:: PMC8983141

Article PDF–22M

Select item 78518672.

Coordination of Grp1 recruitment mechanisms by its phosphorylation

Jian Li, David G. Lambright, Victor W. Hsu

Mol Biol Cell. 2020 Dec 1; 31(25): 2816–2825. doi: 10.1091/mbc.E20-03-0173

PMCID:: PMC7851867

Article PDF–1.3M

Select item 33169073.

Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity

Daming Zuo, Xiaofei Yu, Chunqing Guo, Huanfa Yi, Xing Chen, Daniel H. Conrad, Tai L. Guo, Zhengliang Chen, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang

FASEB J. 2012 Apr; 26(4): 1493–1505. doi: 10.1096/fj.11-197707

PMCID:: PMC3316907

Article

Select item 30910264.

Tumor secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumor immune response in vivo

Hilal Arnouk, Evan R. Zynda, Xiang-Yang Wang, Bonnie L. Hylander, Masoud H. Manjili, Elizabeth A. Repasky, John R. Subjeck, A. Latif Kazim

Int J Hyperthermia. Author manuscript; available in PMC 2011 May 10.

Published in final edited form as: Int J Hyperthermia. 2010; 26(4): 366–375. doi: 10.3109/02656730903485910

PMCID:: PMC3091026

Article PDF–1.5M

Select item 27900825.

Secretion of stress protein grp170 promotes immune-mediated inhibition of murine prostate tumor

Ping Gao, Xiaolei Sun, Xing Chen, John Subjeck, Xiang-Yang Wang

Cancer Immunol Immunother. 2009 Aug; 58(8): 1319–1328. Published online 2009 Jan 14. doi: 10.1007/s00262-008-0647-6

PMCID:: PMC2790082

Article PDF–512K

Select item 2094176.

Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity

Yasuko Kitao, Kentaro Ozawa, Mayuki Miyazaki, Michio Tamatani, Tomohiro Kobayashi, Hideki Yanagi, Masaru Okabe, Masahito Ikawa, Tetsumori Yamashima, David M. Stern, Osamu Hori, Satoshi Ogawa

J Clin Invest. 2001 Nov 15; 108(10): 1439–1450. doi: 10.1172/JCI12978

PMCID:: PMC209417

Article PDF–7.2M

Select item 99232277.

FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response

Zhe Wang, Chen Tan, Caihan Duan, Junhao Wu, Dan Zhou, Lingzhi Hou, Wei Qian, Chaoqun Han, Xiaohua Hou

Redox Biol. 2023 Apr; 60: 102618. Published online 2023 Jan 28. doi: 10.1016/j.redox.2023.102618

PMCID:: PMC9923227

Article PDF–17M

Select item 67303258.

ORP150/HSP12A Regulates Purkinje Cell Survival: A Role for Endoplasmic Reticulum Stress in Cerebellar Development

Yasuko Kitao, Kouichi Hashimoto, Tomohiro Matsuyama, Hiroyuki Iso, Takeshi Tamatani, Osamu Hori, David M. Stern, Masanobu Kano, Kentaro Ozawa, Satoshi Ogawa

J Neurosci. 2004 Feb 11; 24(6): 1486–1496. doi: 10.1523/JNEUROSCI.4029-03.2004

PMCID:: PMC6730325

Article PDF–1.1M

Select item 39084229.

The Large Hsp70 Grp170 Binds to Unfolded Protein Substrates in Vivo with a Regulation Distinct from Conventional Hsp70s

Julia Behnke, Linda M. Hendershot

J Biol Chem. 2014 Jan 31; 289(5): 2899–2907. Published online 2013 Dec 10. doi: 10.1074/jbc.M113.507491

PMCID:: PMC3908422

Article PDF–3.9M

Select item 306416610.

Involvement of Oxygen-regulated Protein 150 in AMP-activated Protein Kinase-mediated Alleviation of Lipid-induced Endoplasmic Reticulum Stress

Yun Wang, Zeyu Wu, Dan Li, Duan Wang, Xiaoming Wang, Xiang Feng, Min Xia

J Biol Chem. 2011 Apr 1; 286(13): 11119–11131. Published online 2011 Feb 4. doi: 10.1074/jbc.M110.203323

PMCID:: PMC3064166

Article PDF–2.0M

Select item 302560211.

Secretable Chaperone Grp170 Enhances Therapeutic Activity of a Novel Tumor Suppressor Mda-7/IL-24

Ping Gao, Xiaolei Sun, Xing Chen, Yanping Wang, Barbara A. Foster, John Subjeck, Paul B. Fisher, Xiang-Yang Wang

Cancer Res. Author manuscript; available in PMC 2011 Jan 24.

Published in final edited form as: Cancer Res. 2008 May 15; 68(10): 3890–3898. doi: 10.1158/0008-5472.CAN-08-0156

PMCID:: PMC3025602

Article PDF–737K

Select item 279214712.

Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco–Sjögren syndrome

Lihong Zhao, Christine Rosales, Kevin Seburn, David Ron, Susan L. Ackerman

Hum Mol Genet. 2010 Jan 1; 19(1): 25–35. Published online 2009 Oct 3. doi: 10.1093/hmg/ddp464

PMCID:: PMC2792147

Article PDF–564K

Select item 385838513.

Enhanced ER entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination

Hongxia Wang, Xiaofei Yu, Chunqing Guo, Daming Zuo, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang

J Immunol. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: J Immunol. 2013 Dec 15; 191(12): 10.4049/jimmunol.1302312. Published online 2013 Nov 11. doi: 10.4049/jimmunol.1302312

PMCID:: PMC3858385

Article PDF–3.1M

Select item 12606814.

A novel type of co-chaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomes

Johanna Dudek, Jörg Volkmer, Christiane Bies, Silvia Guth, Anika Müller, Monika Lerner, Peter Feick, Karl-Herbert Schäfer, Eberhard Morgenstern, Fritha Hennessy, Gregory L. Blatch, Katja Janoscheck, Nicole Heim, Petra Scholtes, Michael Frien, Wolfgang Nastainczyk, Richard Zimmermann

EMBO J. 2002 Jun 17; 21(12): 2958–2967. doi: 10.1093/emboj/cdf315

PMCID:: PMC126068

Article PDF–405K

Select item 974691615.

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2

Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia

JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908

PMCID:: PMC9746916

Article PDF–7.1M

Select item 13864616.

A Subset of Chaperones and Folding Enzymes Form Multiprotein Complexes in Endoplasmic Reticulum to Bind Nascent Proteins

Laurent Meunier, Young-Kwang Usherwood, Kyung Tae Chung, Linda M. Hendershot

Mol Biol Cell. 2002 Dec; 13(12): 4456–4469. doi: 10.1091/mbc.E02-05-0311

PMCID:: PMC138646

Article PDF–437K

Select item 474776817.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Article PDF–1.0M

Select item 665555118.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Article PDF–1020K

Select item 260547919.

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives

Owen J Tamplin, Doris Kinzel, Brian J Cox, Christine E Bell, Janet Rossant, Heiko Lickert

BMC Genomics. 2008; 9: 511. Published online 2008 Oct 30. doi: 10.1186/1471-2164-9-511

PMCID:: PMC2605479

Article PDF–1.7M

Select item 624418320.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Article PDF–753K

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