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Select item 94860171.

Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome

Bin Ni, Shanshan Chen, Kathleen A. Ryan, Michael L. Maitland, Jared S. Farrar, Martin Witzenrath, Birgitt Gubier, Cindy Serdjebi, Karine Bertotti, Rui Wang, Fadi N. Salloum, Luigi Marino, Braxton D. Mitchell, Francesco S. Celi

Mol Metab. 2022 Nov; 65: 101588. Published online 2022 Aug 30. doi: 10.1016/j.molmet.2022.101588

PMCID:: PMC9486017

Article PDF–2.7M

Select item 82922902.

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

Fabiana Baganha, Rob C. M. de Jong, Erna A. Peters, Wietske Voorham, J. Wouter Jukema, Mirela Delibegovic, Margreet R. de Vries, Paul H. A. Quax

Angiogenesis. 2021; 24(3): 567–581. Published online 2021 Feb 7. doi: 10.1007/s10456-021-09767-9

PMCID:: PMC8292290

Article PDF–11M

Select item 68552783.

Role of Lymphatic Deficiency in the Pathogenesis and Progression of Inflammatory Bowel Disease to Colorectal Cancer in an Experimental Mouse Model

Sarah K Daley, Marlys H Witte, Jalicia Washington, Michael Bernas, Pawel Kiela, Jennifer Thorn, Nathan Tanoue, J Steven Alexander

Inflamm Bowel Dis. 2019 Dec; 25(12): 1919–1926. Published online 2019 Jun 7. doi: 10.1093/ibd/izz112

PMCID:: PMC6855278

Article PDF–6.9M

Select item 53912034.

Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

Yu A An, Kai Sun, Nolwenn Joffin, Fang Zhang, Yingfeng Deng, Olivier Donzé, Christine M Kusminski, Philipp E Scherer

eLife. 2017; 6: e24071. Published online 2017 Mar 29. doi: 10.7554/eLife.24071

PMCID:: PMC5391203

Article PDF–6.6M

Select item 50194435.

Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes

Payal Shah, Navina Lueschen, Amin Ardestani, Jose Oberholzer, Johan Olerud, Per-Ola Carlsson, Kathrin Maedler

PLoS One. 2016; 11(9): e0161834. Published online 2016 Sep 12. doi: 10.1371/journal.pone.0161834

Correction in:: PLoS One. 2023; 18(3): e0282771.

PMCID:: PMC5019443

Article PDF–2.5M

Select item 45493956.

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

Thomas L. Theelen, Jari P. Lappalainen, Judith C. Sluimer, Erika Gurzeler, Jack P. Cleutjens, Marion J. Gijbels, Erik A.L. Biessen, Mat J.A.P. Daemen, Kari Alitalo, Seppo Ylä-Herttuala

Atherosclerosis. 2015 Aug; 241(2): 297–304. doi: 10.1016/j.atherosclerosis.2015.05.018

PMCID:: PMC4549395

Article

Select item 43423287.

Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2

Doruk Keskin, Jiha Kim, Vesselina G. Cooke, Chia-Chin Wu, Hikaru Sugimoto, Chenghua Gu, Michele De Palma, Raghu Kalluri, Valerie S. LeBleu

Cell Rep. Author manuscript; available in PMC 2016 Feb 24.

Published in final edited form as: Cell Rep. 2015 Feb 24; 10(7): 1066–1081. Published online 2015 Feb 19. doi: 10.1016/j.celrep.2015.01.035

PMCID:: PMC4342328

Article PDF–4.7M

Select item 41027668.

Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions

Wei Zheng, Harri Nurmi, Sila Appak, Amélie Sabine, Esther Bovay, Emilia A. Korhonen, Fabrizio Orsenigo, Marja Lohela, Gabriela D’Amico, Tanja Holopainen, Ching Ching Leow, Elisabetta Dejana, Tatiana V. Petrova, Hellmut G. Augustin, Kari Alitalo

Genes Dev. 2014 Jul 15; 28(14): 1592–1603. doi: 10.1101/gad.237677.114

PMCID:: PMC4102766

Article PDF–2.5M

Select item 40393809.

Role of Angiopoietin-2 in Corneal Lymphangiogenesis

Don Yuen, Sammy Grimaldo, Roberto Sessa, Tatiana Ecoiffier, Tan Truong, Eric Huang, Michael Bernas, Sarah Daley, Marlys Witte, Lu Chen

Invest Ophthalmol Vis Sci. 2014 May; 55(5): 3320–3327. Published online 2014 May 29. doi: 10.1167/iovs.13-13779

PMCID:: PMC4039380

Article PDF–620K

Select item 373428310.

Angiopoietin-2 Is Critical for Cytokine-Induced Vascular Leakage

Andrew V. Benest, Karoline Kruse, Soniya Savant, Markus Thomas, Anna M. Laib, Elias K. Loos, Ulrike Fiedler, Hellmut G. Augustin

PLoS One. 2013; 8(8): e70459. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0070459

PMCID:: PMC3734283

Article PDF–816K

Select item 358780911.

Angiopoietin-2 is vasoprotective in the acute phase of cerebral ischemia

Léna Marteau, Samuel Valable, Didier Divoux, Simon A Roussel, Omar Touzani, Eric T MacKenzie, Myriam Bernaudin, Edwige Petit

J Cereb Blood Flow Metab. 2013 Mar; 33(3): 389–395. Published online 2012 Dec 5. doi: 10.1038/jcbfm.2012.178

PMCID:: PMC3587809

Article PDF–474K

Select item 354011612.

PTH Enhanced Structural Allograft Healing is Associated with Decreased Angiopoietin-2 Mediated Arteriogenesis, Mast Cell Accumulation and Fibrosis

Robinder S. Dhillon, Chao Xie, Wakenda Tyler, Laura M. Calvi, Hani A. Awad, Michael J. Zuscik, Regis J. O’Keefe, Edward M. Schwarz

J Bone Miner Res. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: J Bone Miner Res. 2013 Mar; 28(3): 586–597. doi: 10.1002/jbmr.1765

PMCID:: PMC3540116

Article PDF–2.9M

Select item 351447413.

Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth

Patrick Nasarre, Markus Thomas, Karoline Kruse, Iris Helfrich, Vivien Wolter, Carleen Deppermann, Dirk Schadendorf, Gavin Thurston, Ulrike Fiedler, Hellmut G. Augustin

Cancer Res. Author manuscript; available in PMC 2012 Dec 5.

Published in final edited form as: Cancer Res. 2009 Feb 15; 69(4): 1324–1333. Published online 2009 Feb 10. doi: 10.1158/0008-5472.CAN-08-3030

PMCID:: PMC3514474

Article PDF–1.7M

Select item 326014114.

Angiopoietin 2 Alters Pancreatic Vascularization in Diabetic Conditions

Sophie Calderari, Cécile Chougnet, Maud Clemessy, Hervé Kempf, Pierre Corvol, Etienne Larger

PLoS One. 2012; 7(1): e29438. Published online 2012 Jan 17. doi: 10.1371/journal.pone.0029438

PMCID:: PMC3260141

Article PDF–759K

Select item 288163215.

Angiopoietin-2 in experimental colitis

Vijay C. Ganta, Walter Cromer, Ginny L. Mills, James Traylor, Merilyn Jennings, Sarah Daley, Benjamin Clark, J. Michael Mathis, Michael Bernas, Paul Jordan, Marlys Witte, J. Steven Alexander

Inflamm Bowel Dis. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Inflamm Bowel Dis. 2010 Jun; 16(6): 1029–1039. doi: 10.1002/ibd.21150

PMCID:: PMC2881632

Article PDF–866K

Select item 261317716.

Angiopoietin-2 Stimulates Blood Flow Recovery After Femoral Artery Occlusion by Inducing Inflammation and Arteriogenesis

Sarah L. Tressel, Hyongbum Kim, Chih-Wen Ni, Kyunghwa Chang, Juan C. Velasquez-Castano, W. Robert Taylor, Young-sup Yoon, Hanjoong Jo

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2009 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Nov; 28(11): 1989–1995. Published online 2008 Sep 4. doi: 10.1161/ATVBAHA.108.175463

PMCID:: PMC2613177

Article PDF–1.8M

Select item 787137417.

Blood angiopoietin-2 predicts liver angiogenesis and fibrosis in hepatitis C patients

Yosuke Osawa, Sachiyo Yoshio, Yoshihiko Aoki, Masaaki Korenaga, Masatoshi Imamura, Takashi Oide, Miku Okawara, Hironari Kawai, Yuriko Tsutsui, Yuichi Yoshida, Shiori Yoshikawa, Taizo Mori, Taiji Yamazoe, Tatsuya Kanto

BMC Gastroenterol. 2021; 21: 55. Published online 2021 Feb 8. doi: 10.1186/s12876-021-01633-8

PMCID:: PMC7871374

Article PDF–1.9M

Select item 761117518.

Tumor cell-derived Angiopoietin-2 promotes metastasis in melanoma

Ashik Ahmed Abdul Pari, Mahak Singhal, Corinne Hübers, Carolin Mogler, Benjamin Schieb, Anja Gampp, Nicolas Gengenbacher, Louise E. Reynolds, Dorothee Terhardt, Cyrill Géraud, Jochen Utikal, Markus Thomas, Sergij Goerdt, Kairbaan Hodivala-Dilke, Dr. Hellmut G. Augustin, Dr. Moritz Felcht

Cancer Res. Author manuscript; available in PMC 2021 Jul 10.

Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2586–2598. Published online 2020 Apr 17. doi: 10.1158/0008-5472.CAN-19-2660

PMCID:: PMC7611175

Article PDF–2.7M

Select item 710892519.

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS

Zhilin Li, Emilia A. Korhonen, Arianna Merlini, Judith Strauss, Eleonoora Wihuri, Harri Nurmi, Salli Antila, Jennifer Paech, Urban Deutsch, Britta Engelhardt, Sudhakar Chintharlapalli, Gou Young Koh, Alexander Flügel, Kari Alitalo

J Clin Invest. 2020 Apr 1; 130(4): 1977–1990. Published online 2020 Mar 9. doi: 10.1172/JCI130308

PMCID:: PMC7108925

Article PDF–13M

Select item 706748620.

Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection

Brandon Trent, Yuejin Liang, Yan Xing, Marisol Esqueda, Yang Wei, Nam-Hyuk Cho, Hong-Il Kim, Yeon-Sook Kim, Thomas R. Shelite, Jiyang Cai, Jiaren Sun, Donald H. Bouyer, Jinjun Liu, Lynn Soong

PLoS Negl Trop Dis. 2020 Mar; 14(3): e0007675. Published online 2020 Mar 2. doi: 10.1371/journal.pntd.0007675