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Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-1 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB170 by luminescence induction assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 by luminescence induction assay
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-1 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 by luminescence induction assay
Inhibition of His-tagged Vibrio cholerae recombinant MTAN expressed in Escherichia coli B21 by spectrophotometry
Assay data:3 Active, 3 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of Vibrio cholerae recombinant MARTX toxin (3391-3650) cysteine protease domain autoprocessing assessed as concentration of InsP6 required to activate half maximal cleavage of the enzyme at 10 uM by Coomassie staining based SDS-PAGE method
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Vibrio cholerae neuraminidase assessed as inhibition of 4-MU-NANA hydrolysis after 30 mins by spectrofluorimetry
Assay data:3 Active, 1 Activity ≤ 1 µM, 16 Tested
Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB170 at 1 uM by luminescence induction assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 at 1 uM by luminescence induction assay
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Vibrio cholera N16961 MTAN -mediated adenine production by reverse-phase HPLC
Assay data:3 Tested
Antimicrobial activity against Vibrio cholerae N16961 assessed as effect on cell growth up to 1 uM
Assay data:4 Tested
SummaryPubMed Citation
Inhibition of Vibrio cholerae N16961 MTAN-mediated autoinducer-1 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 at 1 uM by luminescence induction assay
Inhibition of MARTX toxin cysteine protease domain autoprocessing in Vibrio cholerae assessed as assessed as reduction in actin cross linking in HFF cells exposed to Vibrio cholerae supernatants pretreated at 50 uM for 15 mins by Western blot
SummaryCompounds, ActivePubMed Citation
Inhibition of MARTX toxin cysteine protease domain autoprocessing at Leu3099 residue in wild type Vibrio cholerae at >50 uM by Western blot
Inhibition of MARTX toxin cysteine protease domain autoprocessing at Leu3441 residue in wild type Vibrio cholerae at 100 uM by Western blot
Inhibition of MARTX toxin cysteine protease domain autoprocessing in wild type Vibrio cholerae by Western blot
Inhibition of Vibrio cholerae MARTX toxin cysteine protease domain autoprocessing assessed as assessed as reduction in actin cross linking in HFF cells at 50 uM pretreated for 15 before Vibrio cholerae supernatants addition by Western blot
Assay data:1 Active, 3 Tested
Inhibition of Vibrio cholerae recombinant MARTX toxin (3391-3650) cysteine protease domain autoprocessing assessed as reduction of GTPgamma-S-induced activation of protease activity at 100 uM after 15 mins by Coomassie staining based SDS-PAGE method
Assay data:10 Active, 10 Tested
Inhibition of Vibrio cholerae glycoside hydrolase NagZ
Antibacterial activity against Vibrio cholerae 16961 infected in human HeLa cells assessed as inhibition of bacterial adherence to host cell at 3 to 10 ug/ml pre-incubated for 1 hr before infection measured after 30 mins of infection by Giemsa staining
Assay data:1 Active, 1 Tested
Antibacterial activity against Vibrio cholerae 16961 at 3 to 10 ug/ml after 24 hrs
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